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HS Code |
747324 |
| Chemical Name | Lithium Citrate Tetrahydrate |
| Chemical Formula | Li3C6H5O7·4H2O |
| Molecular Weight | 237.97 g/mol |
| Appearance | White crystalline powder |
| Solubility In Water | Freely soluble |
| Melting Point | Decomposes before melting |
| Cas Number | 6080-58-6 |
| Storage Conditions | Store in a cool, dry place |
| Ph Value | Approximately neutral in aqueous solution |
| Uses | Pharmaceuticals, mood stabilization research |
| Density | 1.46 g/cm³ |
| Stability | Stable under recommended storage conditions |
As an accredited Lithium Citrate Tetrahydrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 100g Lithium Citrate Tetrahydrate is securely packed in a sealed, labeled HDPE bottle with safety data and handling instructions. |
| Shipping | Lithium Citrate Tetrahydrate should be shipped in tightly sealed containers to prevent moisture absorption and contamination. Store and transport in a cool, dry place, away from incompatible substances. Package according to local regulations and ensure proper labeling. This chemical is not classified as hazardous for transport but handle with standard precautions. |
| Storage | **Lithium Citrate Tetrahydrate** should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from moisture and incompatible substances such as strong acids and oxidizers. Keep it away from direct sunlight and sources of ignition. Ensure the container is clearly labeled, and store at room temperature to maintain chemical stability. |
Applications of Lithium Citrate Tetrahydrate in Industrial ManufacturingAs a direct manufacturer of Lithium Citrate Tetrahydrate, we serve industrial customers across multiple downstream sectors, supporting specialized formulations and production requirements. The following sections provide detailed application insights for primary usage scenarios based on real industrial practice, regulatory frameworks, and our long-term supply experience. 1. Psychiatric Pharmaceutical Salt ProductionLeading pharmaceutical producers use lithium citrate tetrahydrate to synthesize oral and parenteral lithium formulations for mood stabilization. This ingredient is preferred within lithium therapy due to its solubility profile, compliance with pharmacopoeial requirements, and suitable citrate counter-ion for biocompatible applications. In psychiatric drug manufacturing, controlled addition during wet granulation or solution compounding ensures API purity and proper lithium dosing per GMP protocols while maintaining consistent quality throughout batch production. Industry compliance standards
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2. Food Fortification Additive (Trace Lithium Enrichment)Specialty food supplement processors adopt lithium citrate tetrahydrate as a source of trace lithium for fortifying functional foods or dietary supplements. Compliance with local food additive registries and permitted levels is mandatory, with dosing carefully controlled to provide safe micro-quantities. The raw material is dissolved in aqueous carriers or pre-mixes, ensuring homogenous dispersion before blending into finished powders, bars, or beverages, with continuous batch QC to verify exact lithium delivery within legal limits. Industry compliance standards
Typical usage ratio
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3. Ceramics and Glass Industrial FluxesGlass and ceramics manufacturers utilize lithium citrate tetrahydrate as a specialized fluxing agent, taking advantage of the lithium ion’s ability to lower melting points and improve thermal expansion properties. The material dissolves quickly during the batch mix stage, aiding silica and alumina network modification in technical glasses and ceramic frits. Consistent composition and low trace metal impurities support high transparency and color stability in glass batches, along with energy savings in kilns and reduced bubble formation during firing. Industry compliance standards
Typical usage ratio
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4. Lithium Reference Reagent for Analytical LaboratoriesAccredited laboratories use high-purity lithium citrate tetrahydrate as a standard reference material for lithium analyses by atomic absorption, ICP-OES, or ion chromatography methods. Certified batch traceability, defined water of crystallization, and stable lithium yield are essential for preparing calibration standards and matrix-matched controls. Laboratories rely on precise weighing and quantitative dissolution to ensure data validity throughout quality assurance and instrument calibration cycles. Industry compliance standards
Typical usage ratio
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5. Specialty Electrolyte Component for High-Temperature BatteriesCertain producers of high-temperature and specialized lithium battery systems incorporate lithium citrate tetrahydrate into experimental electrolyte formulations. The citrate function enhances the structural stability of polymer or organic matrix electrolytes, assisting ion mobility and thermal stability. Only a few application segments have developed proprietary methods for integrating citrate-based lithium sources, especially in prototype energy storage modules. Strict moisture control and batch consistency support the reproducibility required in battery pilot lines. Industry compliance standards
Typical usage ratio
Downstream process integration
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The journey of lithium compounds has moved far from the days of raw extraction. Our Lithium Citrate Tetrahydrate stands as a direct result of what we’ve learned on the production floor, in research labs, and through day-to-day feedback from partners who put our product in real-world applications. Lithium Citrate Tetrahydrate is not a commodity pulled from a warehouse shelf; it’s the outcome of hands-on tuning and persistent quality checks at every stage of manufacture. Knowing what goes in and what comes out has allowed us to shape a predictable, useful, and safe compound.
We never treat Lithium Citrate Tetrahydrate as just another compound. Each batch starts with technical-grade lithium carbonate, which we refine and react under controlled parameters to reach a tetrahydrate form. The tetrahydrate state brings a significant advantage in handling and solubility—these aren’t just buzzwords tossed around by marketers. From the raw lithium salts to the crystalline structure in the final drum, our staff sees it all, adjusting conditions as needed, measuring batch yields, tracking minor impurities, and recording observations that only come from years in the plant. This attention to detail in crystallization means our product dissolves reliably and consistently during downstream processing.
Purity levels remain a prime concern. While no chemical plant deals in wishful thinking, we’ve driven down sodium and potassium contaminants through real process tweaks, not shortcuts. Realistically, trace metals, moisture, and unwanted ions matter even at parts-per-million levels for our clients—whether the compound is headed to pharmaceutical QA offices or to specialty ceramics labs. Our technicians run regular checks with ICP-OES and loss-on-drying methods, and we use actual calibration curves, not hoped-for values, to minimize out-of-spec batches. Granule size might not come up at conferences, but anyone who’s tried to feed a dusty, uneven powder in an automated mixer knows why we focus on consistent particle formation without caking agents. These qualities aren’t marketing flourishes; they’re the outcome of decades standing next to steam lines, not behind PowerPoint slides.
Chemists—practical, lab-worn chemists—often debate why the tetrahydrate form matters over anhydrous or lower-hydrate lithium citrate salts. We listen, and we’ve seen how the water of crystallization in the tetrahydrate brings measurable benefits. It dissolves easily and completely in water, which simplifies solution preparation for clinicians, researchers, or manufacturing engineers. Consistent hydration means predictable concentrations batch after batch, which keeps test results and formulations on target. We have heard, over the years, the headache stories when suppliers mix up hydrates. We’ve built labeling, traceability, and batch tracking that spot those issues before drums leave the gate. Being the original manufacturer gives us the responsibility to prevent these simple, costly mistakes.
Experience on the floor has also shown us why pharmaceutical applications care about hydrate content and purity. Whether Lithium Citrate Tetrahydrate goes into a blood-buffering formulation or acts as a precursor for organolithium compounds, stray ions and wrong hydration numbers spell trouble. We maintain and document steady, repeatable loss-on-drying and XRD results, not just for regulatory reasons but to spare our customers downstream rework and rejected batches. Unlike traders focused on inventory spreadsheets, we have to live with the practical outcomes of our chemistry—that means fewer callbacks, fewer emergency shipments, and more trust in the supply chain.
For us, every ton shipped marks the end of months of hands-on effort. Pharmaceutical makers use Lithium Citrate Tetrahydrate because it handles easily and fits established monograph requirements without fuss. Its reliable solubility helps in oral therapeutic agents where batch-to-batch inconsistency isn’t an option. We’ve spent tense phone calls with production leads troubleshooting why a batch set up too slow, only to trace it to a different hydrate variant from another source. Choosing the right tetrahydrate from the start prevents days lost and costs ballooning needlessly. Our staff follows up with end users, and their feedback has driven improvements in filtration, drying, and packaging processes over the years.
Veterinary medicine, chemical synthesis, and ceramics each demand their own spec sheets, but the fundamental user requirement never changes: the material must work exactly as the specification says. In veterinary and psychopharmacological applications, there’s little margin for error—residual metals, pH drift, or unexpected caking during storage can set back progress or risk compliance. Over the decades, we’ve learned how crucial open documentation and hands-on sample verification are for keeping trust. Our quality assurance team tracks samples as far as a year after delivery, checking if real-world storage matches lab projections. These lessons—earned through both failures and successes—remind us that our job does not end at the loading dock.
In this industry, numbers matter. The formula for Lithium Citrate Tetrahydrate is Li3C6H5O7·4H2O, with a molecular mass calculated—down to the fractional digit—so customers know what they have in each shipment. Our process keeps moisture levels controlled within strict, internally verified ranges. Particle size distribution often lands between 50 and 300 microns, never going too fine or too coarse, based on feedback from blenders and formulation teams. Solubility in deionized water at standard temperatures consistently matches reference monographs; we run real-time QA, not just after-the-fact batch certificates.
We don’t chase superficial “purity” numbers just for marketing. Instead, we work from experienced plant know-how, always asking what matters most to the end process. Trace sodium, potassium, and calcium are kept to single-digit ppm—again, not just for appearances, but because we’ve seen firsthand the headaches when these creep higher. While sometimes industry talk drifts into “minimum compliance,” on our end, it’s about minimizing hassle for the next person using the product. Documentation comes concise, clear, and free from recycled jargon because our own plant crews demand it. If a batch misses an internal spec, we rework it or scrap it. That costs money and time, but it also saves relationships we’ve spent years building with those who rely on us.
Every manufacturer likes to claim their batch runs at the highest quality, but the field proves otherwise. Batches straight from trading channels often come with surprises—batch-to-batch inconsistency, wrong hydrate level, off-spec pH, or invisible cross-contamination. By owning our production vessels, traceable inputs, and maintenance schedules, we spot problems before they hit the drums. We don’t need elaborate marketing to know why purity matters; we’ve seen how cross-contamination can cause regulatory knocks on the door, customer audits, and workflow shutdowns at the point of use. Reliable hydrate content, low residual metals, and production transparency let customers plug our material into critical routes with fewer recalculations or extra filtration steps.
Our product’s key feature isn’t just the tetrahydrate label—it’s everything behind it: calibrated moisture, reliable solubility, documented impurity levels, and a supply chain we can explain from mine to final drum. We keep sample retains from every lot so any question about past batches gets a real answer, not a generic apology. We have also built our operations to withstand hiccups in upstream supply by forecasting and pre-qualifying lithium carbonate from more than one approved partner, which cuts the risk of disruption. A forced switch in grade or vendor can upend whole R&D timelines and regulatory filings, so our customers rely on us to keep things steady.
Decisions in pharmaceutical and fine-chemical spheres now hinge on supplier transparency—not from regulatory pressure alone but from lived experience of costly surprises. We routinely invite customers to plant walk-throughs and encourage them to audit our production records. Nothing brings more clarity about a material than watching the processes live—how we manage mother liquors, how we wash and dry crystals, and why we halt a batch if a reading looks off. Many in-house improvements, like adding real humidity-controlled drying or revamping packaging, happened after direct feedback from such visits.
Traceability lets us respond faster to any field issue. We keep control samples at two separate locations with digitally backed batch records connected to input trace numbers. Our team learned this discipline from past incidents where missing a record turned a small query into a week-long investigation. Today, we resolve almost every customer question with retrieved samples and production records from the relevant date. These systems exist not because regulation forced them, but because customer experience says shortcutting documentation never works in the long run.
Specmanship only gets you so far. Field feedback reveals the real test. We have direct relationships with formulation chemists who report how our Lithium Citrate Tetrahydrate performs in actual production, not just on paper. This conversation shapes our plant operations—one week’s feedback from a large-scale formulator prompted us to overhaul our sifting screens for better flow. Another incident, where a drum failed a customer’s peroxide demand test, led us to dig into tank-cleaning protocols until we closed the root cause. Our commitment isn't to printing gold-standard specs, but to keeping that closed loop of practical user input and technical staff experience going. This approach has cut customer complaints year on year and contributes directly to our reliability reputation.
We also welcome returns of off-sample product for our own failure analysis. Drums that get returned don't end up shelved—they go straight for investigation, where real staff look for root causes and trends. Sometimes it's a handling issue; sometimes we catch a small equipment drift before it blossoms into a bigger manufacturing problem. These repairs and learnings feed back into our process instructions and staff training—closing the loop between plant floor realities and customer experience.
Comparing Lithium Citrate Tetrahydrate with other lithium citrate forms—like the monohydrate or anhydrous salt—means more than ticking moisture boxes. In this compound, the presence of four waters not only shifts the calculation of delivered lithium but calms static charge, reduces dusting on transfer, and keeps caking at bay in ambient storage for months on end. We’ve worked with customers who switched, expecting seamless integration with their automated stations, yet found their blenders clogged or their reactors developed unexpected pH drift. The batch-specific nuances, often omitted from generic datasheets, show up in real process runs. Our teams maintain open notes on these lessons so that future customers walk in with clear guidance, reducing their qualification times and minimizing downtime shocks.
We also stake our production reputation on avoiding gray-market or relabeled materials. Anhydrous or impure lithium citrate sometimes enters the distribution chain as the tetrahydrate; these variants will cut corners on yield and risk consistency in formulations intended for pharmaceuticals or precise ceramic batches. Our own origin documentation—direct from starting salt to packed drum—ensures users avoid these pitfalls. This history of transparency isn’t a sales ploy; it’s built from field faults and customer requests for backup data during audits. Our door remains open to new and repeat customers who want not just a nameplate but confidence in every shipment arriving.
Over years of shipping Lithium Citrate Tetrahydrate to markets ranging from regional compounding pharmacies to global R&D labs, we realized packaging and transit often become make-or-break factors. High-visibility drums with integrity seals, anti-static liners, and humidity-absorbing barrier bags have come to define our current packaging. These aren’t value-add gimmicks. Instead, every innovation answers a real shipping issue encountered in the past—from a damp warehouse that swelled drums to a customs delay that exposed material to seasonal weather for weeks. Night and weekend deliveries, sample splitting, and rush batch certifications aren’t extras, but direct responses to client needs, shaped through long-term partnerships and after-action reviews conducted in our own loading bays.
Logistics has grown into a specialty all its own. With Lithium Citrate Tetrahydrate, we’ve seen customs and regulatory challenges spike in certain trade regions. We prepare documentation based on countries’ evolving rules, supply original certificates, and keep a staff member focused on aftermarket support and query resolution. The feedback loop closes with every delivery receipt, every temperature logger we get back, and every packaging design we rebuild after field comments. This dynamic approach has cut delays, reduced loss on delivery, and improved overall customer satisfaction. We put the same grit into these improvements as into process chemistry, knowing any weak link can undo days of precise manufacturing.
Training sits at the core of our operation. The hands that weigh, react, and dry each batch of Lithium Citrate Tetrahydrate have years of plant experience and undergo routine upskilling in both GxP standards and new chemical handling procedures. Our team understands why a small misstep—such as allowing an unfamiliar hydrate variant to slip through—could cause weeks of hardship downstream. We host regular review sessions that gather input from all parts of the operation, from packaging crew right up to plant managers, because no improvement sticks unless it’s learned by those actually moving the material and maintaining the gear.
Our safety approach has evolved with time. Lithium compounds come with inherent health and handling risks; our protocols derive not from checkbox compliance, but from repeated in-plant drills, review of near-miss incidents, and shared industry learnings. Teams use measured PPE based on area use, not generic guidance, and we keep incident logs open for third-party review. Internal emergency drills, regular warehouse climate audits, and active disposal/recycling records close the loop on responsible manufacturing. Every safety tweak responds directly to a previous incident or field report and reflects a long-term goal of maintaining both staff health and customer satisfaction. We draw on generations of staff experience to anticipate, adapt, and refine protocols so that every drum of Lithium Citrate Tetrahydrate ships, stores, and handles smoothly and safely.
The lithium market has felt global shifts—resource pressure, rising regulatory oversight, and increasing expectations for green chemistry. Producing high-quality Lithium Citrate Tetrahydrate means constantly balancing purity with efficiency, cost with sustainability, and batch consistency with scale-up needs. We are running active pilot projects to recapture and reuse process waters, lower overall energy input per kilogram, and further reduce cross-contamination risks during changeovers. Even a minor equipment upgrade, like closed-loop conveyors or improved drying ovens, started as a result of real plant review and feedback from those using the final product.
We’re also watching regulatory changes—such as evolving monograph and REACH standards—because our commitment means preparing for tomorrow’s compliance before it becomes urgent. Meeting future specs calls for embedded expertise, both on the production side and out in the market, sharing knowledge and pooling resources. By working hand in hand with our customers, we hope to anticipate needs rather than chase problems. These efforts don’t spring from external pressure, but from a genuine belief that quality built at the source shields end users from unexpected disruptions, recalls, or costly lab reworking. The more dialog we sustain with our customers, the better positioned we are to answer the next tough quality or regulatory challenge.
What makes our Lithium Citrate Tetrahydrate valuable doesn’t show up with a badge or single test result. The difference starts in our approach to manufacturing, field feedback, user experience, and an unwavering focus on batch consistency. Feedback from customers, years of process improvement, and genuine accountability at every level have shaped a compound that partners can trust for sensitive or large-scale applications. Each shipment rests on the experience of real people who know why every number, every method, and every sample backup matters. Those counting on us aren’t asking for slogans—they expect consistency, safety, and transparency grounded in experience, and that’s exactly what we keep delivering, run after run, drum after drum.