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L(-)-Carvone

    • Product Name L(-)-Carvone
    • Alias carvone-l
    • Einecs 225-034-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    405503

    Cas Number 6485-40-1
    Molecular Formula C10H14O
    Molecular Weight 150.22 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Spearmint-like
    Purity ≥98%
    Melting Point -16 °C
    Boiling Point 231-233 °C
    Density 0.96 g/cm³ at 25 °C
    Optical Rotation [α]D20 -61° to -65°
    Solubility Insoluble in water, soluble in organic solvents
    Flash Point 93 °C
    Refractive Index 1.495 - 1.497 at 20 °C
    Storage Temperature Store at 2-8 °C
    Synonyms L-Carvone, (S)-Carvone

    As an accredited L(-)-Carvone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100 mL amber glass bottle, tightly sealed, labeled "L(-)-Carvone, ≥98%, CAS 6485-40-1", with hazard pictograms and handling instructions.
    Shipping L(-)-Carvone is shipped in tightly sealed containers, protected from light and moisture, and kept at room temperature. Packages comply with regulations for safe transport of chemicals, including proper labeling and hazard documentation. During shipping, the chemical is handled as a flammable liquid and kept away from incompatible substances and ignition sources.
    Storage L(-)-Carvone should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from direct sunlight, sources of ignition, and incompatible materials such as strong oxidizers. The storage area should be clearly labeled and protected from moisture. Keep the container upright and avoid excessive heat to maintain chemical stability and prevent degradation.
    Application of L(-)-Carvone

    Applications of L(-)-Carvone in Industrial Manufacturing

    L(-)-Carvone serves as a multifunctional chemical intermediate and additive in multiple industrial sectors. As a dedicated chemical raw material manufacturer, we ensure every batch meets stringent production and regulatory standards. Real-world application feedback from downstream users informs the following industry segmentation and usage guidance.

    1. Flavour and Fragrance Compounding for Food Products

    Industrial flavour houses use L(-)-Carvone as a core component when developing mint-type flavour systems, particularly for the confectionery, chewing gum, and oral care segments. The compound provides authentic spearmint notes. Formulators rely on precise blending, integrating L(-)-Carvone post-distillation into concentrated flavour bases for further downstream incorporation into consumable products. All ingredient additions follow strict allergen and migration limits, verified through batch-to-batch quality audits and regulatory checks.

    Industry compliance standards

    • Food Chemicals Codex (FCC)
    • European Union Regulation (EC) No 1334/2008 (flavourings)
    • US FDA 21 CFR 172.515 (synthetic flavouring substances and adjuvants)
    • Global Standards for Food Contact Materials (e.g., China GB 2760, Japan FSL)

    Typical usage ratio

    • 0.05%–1.2% of total flavour oil concentrate, adjusted based on desired intensity and product matrix
    • Final food application usually below 50 ppm

    Downstream process integration

    • Final blended into flavour bases at the compounding stage
    • Delivered to food and confectionery plants for dosing into syrups, doughs, or coatings during batch mixing
    • Subject to in-line QA release before packaging

    Final product types

    • Chewing gum and bubble gum
    • Mint candies
    • Toothpaste and mouthwash
    • Bakery fillings and flavoured syrups

    2. Aroma Ingredients for Fine Fragrance and Cosmetic Formulations

    Leading perfumery and personal care companies utilize L(-)-Carvone as a natural minty top note in both alcoholic fragrance compositions and functional cosmetic products. In-house blending teams handle the material using closed-system dosing and specific olfactive accuracy protocols. Stability testing is performed across solvent bases and emulsion matrices. Only suppliers with validated IFRA and regional cosmetic ingredient documentation can access this supply chain.

    Industry compliance standards

    • International Fragrance Association (IFRA) Guidelines
    • EU Cosmetics Regulation (EC) No 1223/2009
    • REACH Registration (EC 1907/2006)
    • US CTFA INCI listing

    Typical usage ratio

    • 0.02%–0.7% in fine fragrance concentrates
    • Up to 0.3% in rinse-off and leave-on personal care items depending on formula requirements

    Downstream process integration

    • Added during bulk compound blending or directly into alcohol/solvent phases
    • Compatibility tested with other aroma chemicals before scaling up
    • Quality control includes GC-MS verification of batch purity and profile consistency

    Final product types

    • Toilet waters and perfumed sprays
    • Shower gels and shampoos
    • Handwashing liquids with mint scents
    • Lotions and creams with refreshing notes

    3. Agrochemical Formulation—Bio-based Insect Repellent Synthesis

    Formulators in the crop protection and household pest control sector leverage L(-)-Carvone’s natural repellency profile. Manufacturers integrate this molecule into bio-based repellent premixes designed for direct field or domestic application. Processing facilities blend L(-)-Carvone with carrier oils or encapsulate it in polymer matrices for controlled release, using precise metering to comply with local and international pesticide regulations.

    Industry compliance standards

    • US EPA FIFRA (when used as a biopesticide active ingredient)
    • EU Regulation (EC) No 1107/2009 (Plant Protection Products)
    • OECD Test Guidelines for Biopesticide Efficacy
    • ISO 9001:2015 for formulation plants

    Typical usage ratio

    • 1%–5% as a technical active in concentrate
    • Final use dilution at 0.1%–1% depending on target pest and geography

    Downstream process integration

    • Blended with natural carriers or surfactants near end-stage formulation
    • Emulsified into water-based sprays or incorporated into slow-release granules
    • QC sampling for residue and stability tests before batch release

    Final product types

    • Ready-to-use insect repellent sprays
    • Garden and crop field barrier products
    • Pest deterrent granules for public health programs
    • Aromatherapeutic room pest repellent devices

    4. Chiral Intermediate in Pharmaceutical Synthesis

    Custom synthesis facilities and pharmaceutical ingredient manufacturers specify L(-)-Carvone as a chiral building block for several active pharmaceutical ingredient (API) syntheses. This monoterpene supplies the stereochemical foundation for enantioselective pathways, particularly in drugs targeting the central nervous system or antibacterials. Material qualification adheres to multi-level GMP, requiring detailed traceability, impurity profiling, and consistency in chiral purity.

    Industry compliance standards

    • ICH Q7A GMP for Active Pharmaceutical Ingredients
    • US Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.) monographs (where applicable)
    • ISO 9001:2015 for documentation systems
    • Regulatory filings with US FDA/EMA for new drug submissions

    Typical usage ratio

    • 5%–25% in total chiral pool for target intermediate stage in semi-synthetic route
    • Adjusted based on downstream yield and enantiomeric excess requirements

    Downstream process integration

    • Reacted at intermediate synthesis stages under controlled temperature and atmosphere
    • Integrated as a starting material in multi-step chiral amine and lactone synthesis
    • Full analytical documentation accompanies each lot for regulatory submission

    Final product types

    • Active Pharmaceutical Ingredients for CNS and anti-infective medications
    • Intermediates for further chemical modification (e.g., carboxylates, alkaloids)
    • Research-grade reference materials for medicinal chemistry labs
    • Screening libraries for pharmaceutical discovery

    5. Polymer and Resin Industry—Monomer Modifier and Odor Masking Agent

    Producers of specialty polymers and industrial resins use L(-)-Carvone to fine-tune the olfactory profile of reactive monomer mixes and as a functional modifier. The compound is introduced during the pre-polymerization or compounding stage to neutralize undesirable base odors and to impart slight minty notes aligned with customer specifications in automotive, building materials, or consumer goods. All batches undergo in-process monitoring to assess reaction compatibility and end-use odor metrics.

    Industry compliance standards

    • ISO 9001:2015 for manufacturing and quality assurance
    • EU Regulation (EC) No 1907/2006 (REACH) for polymer additives
    • RoHS Directive 2011/65/EU for electronic/housing applications
    • REACH SVHC (Substances of Very High Concern) notifications

    Typical usage ratio

    • 0.1%–2% in monomer or resin compound, based on odor suppression needs and compatibility
    • Adjusted after odor evaluation panels for final approval

    Downstream process integration

    • Blended with liquid monomers prior to polymerization initiation
    • Fed directly into resin kettle or batch reactor under controlled agitation
    • Subjected to post-reaction GC-MS and organoleptic testing

    Final product types

    • Automotive interior plastics
    • Consumer electronics housings
    • Architectural adhesives and sealants
    • Coated fabrics and flooring components

    6. Analytical Standards and Quality Control for Industry Laboratories

    QC and R&D laboratories across food, fragrance, pharma, and agricultural sectors use L(-)-Carvone as a certified reference standard. Laboratories implement this compound for system suitability, instrument calibration, and method validation in GC, GC-MS, and olfactometry. Reference-grade L(-)-Carvone requires exact purity declarations, traceability documentation, and stability records, ensuring all routine and regulatory analyses deliver accurate quantitative and qualitative results.

    Industry compliance standards

    • ISO 17034:2016 for reference material producers
    • ISO/IEC 17025:2017 accredited analytical laboratories
    • USP, Ph. Eur., and JP requirements for reference standards
    • GLP and GMP analytical protocols

    Typical usage ratio

    • Preparation of standard solutions at 1–1000 ppm depending on instrument specification
    • Concentration adjusted to establish calibration curves for method validation

    Downstream process integration

    • Prepared as internal or external calibration standards for instrument set-up
    • Aliquoted into sample vials for sequence runs and peak identification
    • Included in analytical QC documentation for robust audit traceability

    Final product types

    • Analytical standard grade vials for laboratory distribution
    • System suitability solutions for instrument performance qualification
    • Quality control kits for production environments
    • Reference mixtures for proficiency testing
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    Certification & Compliance
    More Introduction

    L(-)-Carvone: Authenticity and Quality from a Dedicated Manufacturer

    L(-)-Carvone—A Close Look at a Time-Tested Ingredient

    In every distillation run we process in our facility, we remember the long tradition behind essential oils and their role in flavor, fragrance, and fine chemistry. L(-)-Carvone, a monocyclic monoterpene ketone with a distinctive, slightly sweet spearmint aroma, stands as one of the most recognizable natural isolates in the world. Our operations focus on amplifying what nature already offers—drawing out the purity and identity of L(-)-Carvone through careful selection and processing of botanical sources such as caraway and dill seeds.

    Model and Specifications—What Manufacturers Look For

    Throughout years of refining our methodologies, we have learned the details that matter to customers. Our L(-)-Carvone is available in industrial grades with a high degree of optical purity (greater than 99% as L(-) isomer), as controlled by gas chromatography with chiral columns. Most lots meet strict requirements for physical appearance: clear, colorless to pale yellow liquid, with a relative density typically ranging between 0.960 and 0.980 at 20°C, and a refractive index in the range 1.495–1.510.

    Our measurement techniques extend beyond just purity; we regularly check for trace impurities such as limonene or dihydrocarvone, as well as residual solvents and water content. The result is a product tailored for applications where trace contamination can ruin a formulation, whether for a sensitive food application, fine fragrance creation, or specialized chemical synthesis.

    Unlike a bulk trader or reseller, we keep tight control of the full production process, from raw material selection to the final lot. That way, end users don't face surprises during scale-up or product changeover.

    Why Usage and Source Matter

    L(-)-Carvone’s presence in the marketplace traces back to its broad use in both flavor and fragrance applications. Decades ago, flavors for chewing gum and oral hygiene products became possible only because reliable isolation and purification made quality L(-)-Carvone accessible at scale. Our facility is able to support large batch requirements for multinational flavor houses, as well as custom volumes for craft perfumers and research laboratories.

    We have seen customers modify their processes to adapt to variations in raw material quality—or even the method of isolation—when switching to lower cost or less traceable products from brokers. Common feedback to us centers on batch consistency: one lot may suppress off-notes in a chewing gum formula, but another triggers flavor changes or unexpected background aromas. Having experienced this firsthand during tech support queries, we understand why purity and process control are not just box-ticking attributes but central to successful product launch and ongoing production.

    Another major customer application lies in the synthesis of chiral intermediates. L(-)-Carvone provides a well-defined chiral building block for the preparation of enantiomerically pure pharmaceuticals, agrochemicals, and advanced materials. The selectivity in downstream reactions depends heavily on the optical purity, and even low levels of D(+)-Carvone or other stereochemical impurities introduce challenges in separation and characterization. As a technical team, we have worked directly with R&D departments to optimize process schemes, sometimes redesigning purification steps after finding inconsistent optical rotation readings from outside suppliers’ material.

    Direct Manufacturing: No Shortcuts Between Plant and Customer

    One key takeaway after years in the industry: manufacturing is not merely about producing a product at a specification but about delivering dependability at each stage. We own and operate the extraction and rectification equipment, choose raw material sources based on seasonal and regional fluctuations, and keep meticulous batch records.

    For our L(-)-Carvone, this means characterizing every received seed lot for oil yield, marker terpenes, and pesticide residues. Multiple extraction runs often show that climatic shifts—droughts, harvest timing, or even changed storage conditions—introduce noticeable differences into the fractionation curves. Our operators learn to adjust cut points so the final L(-)-Carvone always matches agreed spectroscopic reference profiles.

    There’s no layer of reselling or relabeling. Every drum comes stamped with direct manufacturing data and a certificate of analysis backed by validated test methods. Should an issue arise, a customer can trace the full chain from finished product back to local farm lots. This has become increasingly important in audited supply chains, where legacy players may mix different origins or unlabeled process aids for simple resale.

    Differences from Other L(-)-Carvone Products

    Too often the market views materials like L(-)-Carvone as commodities. In daily practice, the differences often emerge in cost-per-formulation, predictability, and trouble-free product scale-up. Nearly every year, we receive samples of so-called L(-)-Carvone that show D/L isomer mixtures or carry over high levels of limonene, especially from synthetic or poorly rectified sources. Even minor off-spec fractions spoil the distinct spearmint aroma or introduce citrus-like notes when blended into finished products.

    Some manufacturers cut corners by blending in synthetic material produced from turpentine or citrus waste, leading to unexpected performance in chiral catalysis or flavor stability. We keep our portfolio based on direct botanical extraction to maintain reliability in both analytical and sensory properties. There’s a reason global brands enforce origin and purity standards—product recalls and consumer complaints cost far more than sourcing from a primary manufacturer committed to transparency.

    We also distinguish our L(-)-Carvone through consistent annual investment in analytic capabilities. Regular use of chiral HPLC, advanced mass spectrometry, and sensory analysis allows us to identify and exclude fractions that may technically pass simple GC purity tests but differ in flavor or odor behavior. Partners in fast-moving consumer goods have shown that minor impurities present at less than one percent will leach out in storage, spoiling shelf-life stability.

    Some users seek D(+)-Carvone, which bears a caraway-like odor—very different in both sensory character and application. We take care to avoid cross-contamination, knowing that optical purity mistakes at the kilogram scale sabotage downstream reactions and can invalidate a QC batch for a pharmaceutical user. In one case, we worked with a team reformulating toothpaste flavor where the earlier product sourced from a trader introduced slight background bitterness through oxidation byproducts. Pure L(-)-Carvone, stabilized with food-grade antioxidants and quality-checked for peroxides, eliminated the off-taste while improving shelf stability. Such nuanced differences drive customer retention and highlight the gap between direct manufacturing and reselling.

    The Human and Environmental Side

    L(-)-Carvone begins as a product of agriculture, and we have developed relationships with farmers over many years to preserve both product quality and environmental outcomes. Seed selection affects not just oil yield but also the input of fertilizer, irrigation, and insect controls. Working directly with growers, our team conducts soil tests and helps manage harvest timing to capture peak oil composition without overspraying or unnecessary interventions.

    Processing efficiency means more than yield per kilogram. Waste minimization, by-product channeling, and solvent recovery all affect the sustainability profile. Our process lines recover residual terpenes for other markets, and by-products return for agricultural use. On-site energy recovery and use of closed-loop systems help bring our L(-)-Carvone production closer to a circular model. That only happens when manufacturing is owned, not separated from the growing fields by layers of brokers chasing quick gains.

    By investing in traceable, direct operations, we support not just safer, more consistent materials, but rural economies and land stewardship. Increasingly, downstream customers ask for full transparency—not just specification sheets, but environmental impact and farming practices. As a manufacturer, we stand behind every container, knowing the value lies not only in chemical structure but in ethical supply and stewardship.

    L(-)-Carvone in Formulation—What Customers Can Rely On

    It’s easy to overlook just how sensitive flavors and fragrances react to subtle changes in input chemicals. Across many years of formulation support, our R&D staff have collected case studies from customers ranging from oral hygiene brands to major beverage players. Some customers reformulate for regulatory reasons or to localize taste; others push the edge in new product development. In every scenario, supply fluctuations—caused by mixing lots or suppliers—have led to flavor drift, shortened shelf life, or even batch rejections.

    Product developers value L(-)-Carvone for its well-characterized sensory profile. In a toothpaste, it brings clean sweetness without the harshness sometimes seen in menthol. In beverages or confectionery, it accentuates green notes without muting other flavors. Bleed-through from D(+)-Carvone or unresolved impurities, as documented by our in-house panel, triggers a shift in perception not captured by automated instruments alone.

    Our process eliminates these sources of error by maintaining continuity in extraction, purification, and storage—supported by regular organoleptic testing. Food safety considerations certainly play a role; customers regularly request documentation on allergens, solvent residues, and pesticide absence, especially for export to high-regulatory countries. Being a primary manufacturer, we can guarantee more reliable compliance and resolution than a reseller who must defer to a distant processor for answers or changes.

    Beyond the Lab—Service and Flexibility Matter

    Manufacturing brings direct feedback. Every time customers confront an issue—a background note that won't go away, a reactivity change in synthesis, a regulatory question—our technical service team receives a call, and often, a sample for joint analysis. This closes the loop between production and application. Over time, we’ve documented hundreds of scenarios where a “clean” COA from a distributor ended in unreliable sensory or reactivity outcomes.

    To address these challenges, we keep open facilities for on-site customer audits and sampling. Product development teams have the chance to see the process from raw seed intake through finished L(-)-Carvone, evaluating both analytic and sensory properties with our in-house staff. We provide guidance on optimal storage, handling, and formulation, adjusting batch sizes to suit both pilot and commercial production.

    Price stability also plays into the value of direct relationships. Feedstock price swings, trade restrictions, and weather events impact availability and cost. We buffer these shocks by holding inventory and locking in supply contracts, a protection not available from speculative brokers who focus on spot arbitrage.

    Innovation—From Carvone to New Chiral Synthetics

    L(-)-Carvone provides more than a pleasant aroma or simple flavoring note. Its chiral structure opens doors for asymmetric synthesis in pharmaceuticals and fine chemicals. Over the years, our technical teams have supplied academic and industrial R&D labs with batches tailor-fit to new catalytic trials. Whether exploring cyclization, reduction, or oxidation, the starting purity and trace element profile matter profoundly for repeatability.

    Competitive manufacturers sometimes cut with D(+)-Carvone or low-purity limonene byproducts, introducing noise into catalytic pathways. We regularly partner with research teams to analyze upstream fractions and guarantee not just isomeric purity but absence of catalytic poisons. Custom batch processing is possible with enough lead time; our process flexibility comes from handling every production step within our own technical environment.

    We have invested in pilot plant lines able to customize input grades—from crude natural extracts to refined isolates meeting narrow pharmaceutical standards. In each case, we bring not just product but deep process understanding—helping accelerate both research timelines and commercial launches. Knowledge gained from this ongoing collaboration feeds back into continuous improvement in routine production.

    Answering to Real-World Demands

    Synthetic alternatives and flavor analogues have grown in the years since we began production, but the natural L(-)-Carvone supply chain remains in demand for reasons both technical and reputational. Global brands insist on authenticated supply, and food safety protocols require QA records traceable to original manufacture. Laboratories seeking new chiral synthons demand a known pedigree for regulatory submission.

    Brokers and intermediaries may provide price advantages on paper, but process breakdowns, recalls, product reformulation, or lost customer trust cost much more in the long run. We see our role as more than a supplier: we serve as a partner through the research, development, and commercialization process, carrying responsibility for every lot.

    That commitment means keeping up with evolving regulatory and sustainability demands, from REACH and GRAS listings to ingredient traceability. As sustainability standards rise, direct manufacturers maintain an edge by controlling every link in the chain, investing in environmental stewardship, and passing those assurances along to customers.

    The Long-Term Perspective

    Decades in this business have proven that trust, transparency, and technical competence outweigh any short-lived supply advantage a broker can promise. Manufacturing from farm to drum allows us to offer L(-)-Carvone with real confidence—meeting both the letter and spirit of quality and supply expectations. At every turn, we value open dialogue with customers, knowing that challenges in application or compliance reflect shared risks and rewards.

    Putting substance behind specification means more than filling an order. In the world of fine chemicals and natural isolates, the smallest details—an untracked impurity, a missed analytical parameter, a skipped farm inspection—can have outsized impacts downstream. We address these through close partnership and direct involvement, investing in both facilities and relationships, and building value step by step.

    L(-)-Carvone, as produced by manufacturers who know the territory, delivers not just a molecular structure but peace of mind—an assurance earned batch after batch. Our record in this field stands as proof that an honest approach, grounded in technical ability and ethical sourcing, benefits everyone from the grower to formulators and end users.