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L-Canavanine Sulfate

    • Product Name L-Canavanine Sulfate
    • Alias L-2-Amino-4-(guanidinooxy)butanoic acid monosulfate salt
    • Einecs 242-016-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    385050

    Product Name L-Canavanine Sulfate
    Chemical Formula C5H12N4O3·H2SO4
    Molecular Weight 276.25 g/mol
    Appearance White to off-white powder
    Solubility Soluble in water
    Storage Temperature 2-8°C
    Purity Typically ≥98%
    Cas Number 24530-65-2
    Synonyms L-Canavanine hemisulfate salt
    Usage Selective agent in microbiology
    Ph Approximately 4.0-6.0 (1% solution in water)
    Stability Stable under recommended storage conditions

    As an accredited L-Canavanine Sulfate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing L-Canavanine Sulfate is packaged in a 10g amber glass bottle with a tamper-evident cap and detailed safety labeling.
    Shipping L-Canavanine Sulfate is shipped in tightly sealed containers to prevent moisture absorption and contamination. It is packaged according to regulatory guidelines for chemicals, typically labeled with hazard and safety information. The shipment is handled under controlled conditions to maintain stability, and documentation accompanies each delivery for traceability and compliance.
    Storage L-Canavanine Sulfate should be stored tightly sealed in a cool, dry, and well-ventilated area, away from incompatible substances. Protect the container from light and moisture. Ideally, store at 2-8°C (refrigerator temperature). Ensure the storage area is clearly labeled and accessible only to authorized personnel trained in handling laboratory chemicals. Dispose of according to institutional and regulatory guidelines.
    Application of L-Canavanine Sulfate

    Applications of L-Canavanine Sulfate in Industrial Manufacturing

    L-Canavanine Sulfate is a functional amino acid derivative with defined roles in several high-value industrial segments. As the original manufacturer, we continuously align formulation and quality management with sector-specific requirements to support mission-critical processes across these downsteam industries.

    1. Pharmaceutical Intermediate in Antineoplastic Research

    L-Canavanine Sulfate enters advanced manufacturing pipelines as a building block for small-molecule research and experimental drugs targeting certain cancer pathways. R&D teams utilize it for its documented role in arginine antagonism and related cellular studies, incorporating strict batch traceability and contamination control prior to downstream reaction assembly. Laboratory and GMP-compliant synthesis operations calibrate inclusion levels based on preclinical protocol, focusing on purity and impurity control when converting to active pharmaceutical intermediates.

    Industry compliance standards

    • USP General Chapter <1045> Biotechnology-Derived Articles
    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • EU Pharmacopoeia Monograph 5.10 for Raw Materials of Biological Origin
    • FDA 21 CFR Part 210-211 for finished pharmaceuticals

    Typical usage ratio

    • 0.5%–2.5% w/w in small-molecule precursor loads; final ratio adjusted after yield/purity testing in preclinical stages

    Downstream process integration

    • Charged into controlled-reactor systems as precursor
    • Subjected to purification and crystallization pre-final synthesis
    • Monitored for residual levels via HPLC in API process validation

    Final product types

    • Investigational antitumor drug intermediates
    • Reference standards for cancer biology studies
    • Clinical trial-grade research APIs
    • Preclinical diagnostic agents

    2. Specialized Additive in Animal Nutrition Trials

    In the animal health sector, L-Canavanine Sulfate is directly utilized for controlled nutrition studies, especially in non-ruminant feed formulations to study metabolic or toxicological effects. Technicians control the dose strictly according to experimental protocol, following GMP and GLP for feed manufacturing pilot plants. High precision blending occurs in micro-ingredient premix lines and compliance with target amino acid levels is confirmed through finished feed QC. Segregated storage and traceable batching ensure sample integrity for research data validity.

    Industry compliance standards

    • FAMI-QS Code of Practice (Feed Additive and Premixture Quality System)
    • OECD Guidelines for the Testing of Chemicals, Section 4
    • EU Regulation (EC) No 1831/2003 on feed additives
    • ISO 22000 Food Safety Management Systems

    Typical usage ratio

    • 0.025–0.1% total diet weight in animal trials; variable per species and trial aim

    Downstream process integration

    • Blended into vitamin and amino acid premixtures
    • Granulated with carrier materials for uniformity
    • Automated batch coding for trial protocol traceability

    Final product types

    • Research livestock feed blends
    • Metabolic study rations for laboratory animals
    • Pilot lots for toxicology reporting
    • Specialty micro-ingredient premixes

    3. Reference Compound in Analytical Standards Production

    L-Canavanine Sulfate serves as a key reference material in the production of certified analytical standards for testing laboratories. Quality control chemists utilize it for calibration curve generation, method validation, and instrument qualification, with batches conforming to ISO and pharmacopoeial standards. Material traceability, precise weighing, and chemical identity certification are strictly enforced throughout blending and bottling operations, supporting reproducible chromatographic and spectroscopic analysis in academic or commercial settings.

    Industry compliance standards

    • ISO 17034 General Requirements for the Competence of Reference Material Producers
    • ISO/IEC 17025 General requirements for testing and calibration laboratories
    • USP General Chapter <11>: Reference Standards
    • EURACHEM/CITAC Guide for Quality Assurance for Reference Materials

    Typical usage ratio

    • Reference solutions prepared at 10–1000 μg/mL depending on analytic method

    Downstream process integration

    • Accurate dissolution into designated solvents
    • Aliquoting into vials under inert atmosphere
    • Lot-specific COA and stability documentation

    Final product types

    • Certified reference standards for HPLC or LC/MS
    • Calibration kits for amino acid analyzers
    • Inter-laboratory proficiency testing samples
    • Stable isotope-labeled derivative standards

    4. Analytical Control in Plant Physiology and Crop Science

    Crop science laboratories employ L-Canavanine Sulfate in assays designed to investigate amino acid profiles or plant defense mechanisms. Research institutions mix it into culture media, hydroponic systems, or tissue extracts, tracking uptake, metabolism, and toxicity in model species. Quality control focuses on batch homogeneity, trace contaminants, and identity confirmation to maintain experimental reproducibility. Protocols reflect compliance with international plant research standards, and blending technicians adjust levels based on pre-defined study endpoints.

    Industry compliance standards

    • GLP (OECD Principles of Good Laboratory Practice)
    • GMP for laboratory reagents (where applicable)
    • ISO 9001 Quality Management for Research Facilities
    • FAO/WHO Codex Alimentarius procedures for analytical reagents

    Typical usage ratio

    • 0.005%–0.05% in nutrient solutions, adjusted for plant species and trial type

    Downstream process integration

    • Dissolved directly into tissue culture media
    • Metered into hydroponic reservoirs for uptake studies
    • Spiked into soil microcosms for controlled experiments

    Final product types

    • Experimental plant growth media
    • Culture kits for academic plant physiology research
    • Reference solutions for crop amino acid profiling
    • Bioassay kits for agronomy laboratories

    5. Tool Compound in Biochemical Screening Libraries

    Biotech firms and contract research organizations integrate high-purity L-Canavanine Sulfate into biochemical compound libraries for high-throughput screening protocols. Screening chemists dispense precise amounts via automated robotic platforms, supporting throughput requirements for drug target interaction and metabolic enzyme profiling. Compliance with reference compound documentation, controlled storage, and batch quality is verified prior to distribution in screening panel lots.

    Industry compliance standards

    • GLP (Good Laboratory Practice, OECD)
    • ISO 9001 Quality Management
    • NIH Assay Guidance Manual best practices
    • GMP for material supplied as research-use only

    Typical usage ratio

    • 2–20 μM in screening assays; set per assay design and target pathway

    Downstream process integration

    • Dilution into microplate wells using automated dispensers
    • Inclusion in reference wells for assay calibration
    • Stability and purity checks prior to panel assembly

    Final product types

    • Biochemical screening compound libraries
    • Validated assay kits for metabolic research
    • Reference panels for academic drug discovery
    • Standardized inhibitor libraries used in CRO screening
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    Certification & Compliance
    More Introduction

    L-Canavanine Sulfate: The Precision Amino Acid Derivative for Modern Research

    Our Approach to Manufacturing L-Canavanine Sulfate

    We’ve spent years developing and refining our process for L-Canavanine Sulfate. Our facility runs with strict adherence to quality controls that catch even subtle deviations in purity or consistency well before product leaves the line. The chemists overseeing production draw on deep experience in both scale-up and analytical testing. There’s real pride in keeping a close watch on every stage – from choice of raw materials through to the final batch check.

    L-Canavanine Sulfate, as we make it, stands out with its clarity, reliability and predictable performance. We don’t just test against standard specifications—we devise batch-specific analytics with regular cross-lab validation. Every shipment carries a traceable lot number, full documentation and our lab’s analytical summary. This approach comes out of encounters with too many stories from our clients about variability with generic suppliers: fluctuating activity, cloudiness, off-odor or foreign particulate. Our priority stays fixed on eliminating these risks.

    What Sets Our L-Canavanine Sulfate Apart

    L-Canavanine Sulfate isn’t just another amino acid analog. We synthesize L-Canavanine Sulfate to a purity above 98% (on anhydrous basis), checked with both HPLC and NMR. The sulfate salt form delivers a product that preserves chemical stability through extended storage and transport. Our process avoids misleading “blending” techniques that can mask off-spec material by pushing marginal product to fill up weight quotas.

    Much of the commercial L-Canavanine on the market today arrives as a base form. That route can make for easier scale-up but invites storage instability, moisture pick-up and pH swings in solution. By committing to the sulfate form and rigorous drying protocols, we protect physical and chemical integrity until you’re ready to weigh out a sample.

    Why L-Canavanine Sulfate Really Matters

    This analog of L-arginine rarely gets the spotlight outside of specialized research domains, yet its activity profile makes it invaluable for certain biochemical and biomedical investigations. Our own R&D team has employed it in selective inhibition assays targeting arginine-utilizing enzymes. Beyond inhibition kinetics, it shows distinctive properties in cell signaling research, plant biochemistry and metabolic studies focused on urea cycle alterations or nitrogen metabolism disruptions.

    We recognize precise consistency in L-Canavanine Sulfate translates directly to data reliability. Clients working with animal cell culture or plant systems repeatedly tell us “batch drift” with off-the-shelf substitutes causes run-to-run variation. Details like minor impurity byproducts, sulfate counterion content or hygroscopicity may sound trivial until they skew an experiment’s baseline or raise unexplained toxicity profiles in cultures. Maintaining the sulfate form’s integrity enables dose titration, extended sample handling and predictable solubility for single or repeated use protocols.

    Rigorous Characterization and Quality Controls

    Our production line never sees shortcuts: Each synthesis run passes through crystallization and multi-stage purification. Every lot undergoes mass spectrometry, 1H and 13C NMR, infrared spectroscopy and two HPLC modes—one focusing on chiral purity, one on residual solvent and degradation markers. Water content falls consistently below 1%, controlled with continuous moisture monitoring after packaging.

    Microbial control, although chemically simple with L-Canavanine Sulfate, never gets neglected. Routine sterility testing tracks viable bioburden even on packaging and closures. Our clean rooms are managed to pharmaceutical-grade standards; all process water for cleaning or crystal washing is validated USP grade. Environmental monitoring reports are always available for review.

    Handling Experience: Insights from Bulk Clients and Lab Routines

    Bulk research clients, especially in biotechnology and agricultural screening, have shared their pain points with impure or inconsistent L-Canavanine. Some batches obtained from trading companies, relabeled through intermediary warehouses, came with clumping, inconsistent particle size or visible oxidation. One group encountered unexplained inhibition in a plant tissue assay—not from the intended arginine antagonism, but from decomposed byproducts even after filtration.

    That’s why our in-house approach insists on non-agglomerated crystals and immediate vacuum-sealing after drying. Product flows clean from the bottle—measured, transferred, dissolved without caking. No off-notes—either in solution or dry powder. The analytical paperwork accompanies every drum, vial or bottle. Our batch records include not just purity, but also full trace of solvents, environmental events during synthesis, and internal calibration curves for activity.

    Specifications and Model Details

    Our primary model consistently meets or exceeds the following profile: L-Canavanine Sulfate dihydrate, CAS number 59-00-7, with confirmed analysis for sulfate ion content and water of crystallization. Purity sits above 98%, and our stated assay reflects an anhydrous basis—never inflated by water weight as some bulk exporters count. Each label reflects net mass, actual water content, and batch-specific sulfate:base ratio.

    From the beginning, we’ve refused to substitute related canavanine salts or bases to save cost. Our process only outputs the sulfate dihydrate, offering predictable solubility in neutral water and robust shelf stability even with fluctuating temperature and humidity in transit.

    Product Handling: From Small-Scale to Bulk

    Ease of use matters. Some amino acid salts go hygroscopic or lumpy almost the minute you crack a seal. Our packaging team works directly with lab users to keep the interior atmosphere below 20% relative humidity during bottling. Each container uses a validated closure system that blocks moisture ingress for at least twelve months unopened, longer than most competitors’ timelines. Even in requests for larger packaging, we insist on subdivided liner-bags inside each drum—no bulk “scooping” from open bins.

    Our technical staff collaborate with client R&D teams on scaling protocols from microgram tests up to kilogram pilot studies. Recent examples include collaborative projects in agbiotech, where frequent sub-sampling played havoc with poorly packed or oxidized canavanine stocks from generic vendors. By providing sub-packed, vacuum-sealed aliquots, we helped eliminate lot-to-lot variation and protected research timelines.

    Differences from Other Suppliers’ Offerings

    Clients frequently approach us after previously dealing with traders or distributors. Material coming through those channels sometimes arrives with vague paperwork, ambiguous salt forms, or lack of full traceability. We’ve also seen supposed “L-Canavanine Sulfate” with unexplained off-white hues, incorrect crystalline appearance, or evidence of partial decomposition. Some resellers don’t clarify whether their sulfate is mono-, di-, or even semi-hydrated, leaving labs to guess at actual molarity.

    As the manufacturer, our chain of custody covers every step—no speculative reporting or white-labeled materials handled by third parties. Our L-Canavanine Sulfate carries single-lot documentation, real-time analytics and zero blending. Every client, from single-vial academic researchers to bulk ag-industry buyers, can audit our workflow and access long-term stability data we’ve built up over years.

    Supporting Research with Reliable Supply

    Many academic teams find themselves recalibrating experiments after switching vendors due to backorders or product recall. We tackled these issues by establishing multi-plant redundancy and over-producing at forecasted peak demand cycles. Our standing agreements with raw material suppliers lock in quality controls from the very start—especially important for specialty amino acids where agricultural raw inputs fluctuate season-to-season.

    By engaging directly with universities and OEM partners, we’ve helped develop sourcing strategies that keep key experiments on schedule. Several multi-year agricultural studies rely on us to supply L-Canavanine Sulfate consistently every season. We treat these commitments as partnerships, integrating custom documentation, batch reservation and direct shipment to each project site.

    Using L-Canavanine Sulfate: Technical Insights

    Labs working with L-Canavanine Sulfate typically focus on enzyme inhibition, anti-metabolite profiling, or cellular uptake mechanisms. We’ve noticed many protocols abandon generic canavanine for our sulfate form due to solubility predictability and the near-total absence of counterion “noise” in controls. One university lab saw their enzyme inhibition curves smooth out immediately after moving from mixed-hydrate canavanine to our product.

    For researchers working below milligram scale, our fine crystalline grade prevents dosing errors and supports reliable titration. Bulk clients in biotech, screening hundreds of compounds per run, highlight our lot-to-lot reproducibility and lack of storage degradation. In our hands, L-Canavanine Sulfate remains colorless, odorless and physically stable for multiple years under standard lab storage.

    Environmental and Safety Considerations

    Our team adheres to industry-leading safety protocols at every stage. Canavanine itself requires careful handling; we maintain segregated workspaces, dedicated air handling, and training programs for anyone on the production line. Wastewater from synthesis routes never leaves our facility without passing through multiple treatment steps to neutralize reactive residues. We test discharge for organonitrogen species and report these metrics to both regulatory and client auditors annually.

    For client labs, we share guidance on handling—glove use, dust control, and secure waste management—to help ensure both product and personnel safety. Our regular training goes beyond compliance, focusing on real mishaps and practical controls. By integrating user feedback into packaging and shipping design, we minimize risk throughout the supply chain.

    Community Contributions and Collaborative Research

    Long-term relationships with researchers give us a front-row view of emerging needs in metabolite analogs. Insights collected from plant pathologists, cancer research groups, and microbial metabolism researchers inform every update to our manufacturing procedures. We invest a fixed portion of our annual margin into collaborative method development—opening our analytical equipment to visiting partners and pilot-testing new detection assays together.

    Recent projects examined canavanine’s selective uptake in nitrogen-fixation mutants, developed faster colorimetric assays for rapid field testing, and worked through the complexities of in vivo delivery for translational medical research. Each collaboration brings unexpected challenges—from scaling up synthesis for classroom demonstrations to purifying specialized isotopomers for advanced spectroscopic studies. These hands-on partnerships keep our processes nimble, our staff vigilant, and our product quality grounded in actual research impact.

    Global Supply, Local Support

    Many of our clients operate at global scale, but need real-time local support. To serve these needs, we’ve set up distributed warehouse points and direct client forums for troubleshooting. Deliveries include not just product, but targeted technical bulletins—covering optimal reconstitution, storage cues, and troubleshooting for persistent experimental anomalies. We commit a real human for every client, not just an anonymous helpdesk email.

    Having spent years untangling supply chain headaches for everything from protein standards to rare metabolite analogs, we understand the tension between price, quality, and assured availability. What sets our L-Canavanine Sulfate program apart comes down to skilled people, carefully managed processes, and an openness with data. Clients report back not just on successful experiments—but also on avoided batch failures, saved weeks of troubleshooting, and reassured funding partners.

    Future Developments and Ongoing Innovation

    Demand for L-Canavanine Sulfate tracks the evolving needs of multidisciplinary research. As studies expand into synthetic biology, metabolic engineering and more complex organism models, our R&D priorities focus on new salt forms, isotopic labeling, and even cost-effective green synthesis routes. We’re piloting solvent-free purification stages and working closely with reagent companies to enable kit-friendly packaging.

    No two projects use L-Canavanine precisely the same way, so our offerings evolve with ongoing input from bench scientists and industry innovators alike. Feedback loops between production, quality assurance, and end-users drive real improvements. By open-sourcing some of our non-proprietary techniques, we’re helping raise the bar across research chemicals—not just for our clients, but for the entire field.

    Conclusion: Reliability Through Manufacture, Not Marketing

    As actual manufacturers, we see the day-to-day realities of chemical supply—both the mundane logistics and the make-or-break details that matter to researchers. L-Canavanine Sulfate, done right, builds trust across a decade of repeated orders and close technical cooperation. We welcome dialogue, scrutiny and challenge, knowing every batch we ship represents not just our reputation, but the foundation of tomorrow’s discoveries in biology, medicine and agriculture.