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L(-)-2-Octanol

    • Product Name L(-)-2-Octanol
    • Alias l-2-octanol
    • Einecs 242-130-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    423101

    Name L(-)-2-Octanol
    Cas Number 4265-23-6
    Molecular Formula C8H18O
    Molecular Weight 130.23
    Appearance Colorless liquid
    Odor Characteristic odor
    Boiling Point 179-181°C
    Density 0.824 g/mL at 25°C
    Refractive Index 1.4290-1.4310
    Optical Rotation [α]D20 -16° to -20° (c=2, ethanol)
    Flash Point 70°C
    Solubility Insoluble in water, soluble in organic solvents

    As an accredited L(-)-2-Octanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100 mL amber glass bottle with a secure cap, labeled "L(-)-2-Octanol," chemical details, hazard symbols, and safety instructions.
    Shipping L(-)-2-Octanol is shipped in tightly sealed containers, protected from light and moisture, and stored in a cool, well-ventilated area. Packages must comply with local, national, and international regulations for transporting flammable liquids. Proper labeling for hazardous chemicals is essential to ensure safe and secure transit. Handle with care to avoid leaks or spills.
    Storage L(-)-2-Octanol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of ignition, heat, and incompatible materials such as strong oxidizers. Keep the container away from direct sunlight and moisture. Proper labeling and secondary containment are recommended to prevent leakage and accidental exposure. Store in accordance with local regulations.
    Application of L(-)-2-Octanol

    Applications of L(-)-2-Octanol in Industrial Manufacturing

    L(-)-2-Octanol is a chiral secondary alcohol used primarily as a select intermediate in various industrial processes. Its high enantiomeric purity and physical properties allow precise performance in chemical synthesis, fragrance formulation, pharmaceutical intermediates, and agrochemical production. The sections below detail core application paths in manufacturing environments.

    1. Synthesis of Chiral Pharmaceutical Intermediates

    Manufacturers in the pharmaceutical sector use this alcohol as a key building block for assembling APIs where enantioselectivity influences activity and regulatory compliance. Its applications center on introducing specific stereochemistry during aldehyde and ketone reductions or as a resolving agent for racemic drug intermediates. This precise control is essential in the synthesis of antihypertensive, antiviral, and central nervous system medicines. Our facility guarantees lot-by-lot traceability to meet customer formulation and QMS checks.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 211: U.S. cGMP for Finished Pharmaceuticals
    • EU GMP Part II for APIs
    • Pharmaceutical grade specification (USP, EP, JP as required)

    Typical usage ratio

    • 0.8–1.2 equivalents relative to the target intermediate, adjusted for stoichiometry in reaction step and yield optimization

    Downstream process integration

    • Added during chiral synthesis or resolution stages; typically reacts with ketones or acids in batch or continuous reactor systems prior to crystallization and purification

    Final product types

    • Chiral drug intermediates (e.g., beta-blockers, antiretrovirals)
    • Finished APIs after further derivatization

    2. Fragrance and Flavors Ingredient Synthesis

    Producers in the aroma chemical industry employ this alcohol to synthesize specialty esters and fragrance components where mild floral and green notes are desirable. Esteemed flavor houses use it as a precursor for octyl esters present in perfume blends and high-stability flavorings. A high purity grade minimizes noise in the final flavor profile and avoids contamination issues during compounding or distillation.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association) for permitted usage in fragrances
    • Food Chemical Codex (FCC) for food-use grades
    • REACH registration for safe handling in EU
    • ISO 9001:2015 for ingredient manufacturing quality management

    Typical usage ratio

    • 0.5–2.5% by weight in fragrance concentrates
    • Up to 0.1% in finished food flavors, subject to organoleptic panel and regulatory limits

    Downstream process integration

    • Introduced in esterification reactors to produce octyl esters; dosed into blending tanks during compounding of fragrance oils or flavors

    Final product types

    • Fine fragrances and perfumes
    • Flavoring agents (octyl acetate, octyl formate, etc.)
    • Personal care product fragrances (lotions, toiletries)

    3. Agrochemical Active Ingredient Manufacturing

    Mainstream crop protection chemical producers select L(-)-2-Octanol for its role as a synthetic intermediate in the formation of chiral agrochemical actives, such as pyrethroids. The raw material’s stereochemistry directly impacts biological activity and regulatory acceptance. Chemical engineers incorporate it into the esterification or etherification routes to generate isomer-specific insecticides with increased selectivity and reduced environmental impact. Batch processes mandate inline GC-QC to control enantiomeric purity.

    Industry compliance standards

    • FAO/WHO JMPR Guidelines on pesticide specification
    • EU Regulation (EC) No 1107/2009 for Plant Protection Products
    • ISO 17025 for pesticide lab analysis
    • Local Environmental and Safety Management Systems (OHSAS 18001, ISO 14001)

    Typical usage ratio

    • 0.9–1.5 molar equivalents depending on synthesis route and required isomeric outcome

    Downstream process integration

    • Dosed into esterification reactions for active ingredient assembly; enters before the chlorination or cyclopropanation steps in batch reactors with continuous temperature control

    Final product types

    • Chiral pyrethroid insecticides
    • Intermediate agri-formulations for further processing

    4. Plasticizer and Polymer Additive Production

    Chemical plants formulating specialty plasticizers and flexible polymers utilize L(-)-2-Octanol in producing octyl esters such as dioctyl phthalate and adipate. The unique branching and chirality enhance compatibility in flexible PVC and TPO compounds and limit migration in sensitive films. Adherence to stringent material and migration standards throughout esterification and compounding protects against regulatory recalls and performance drift during end-use.

    Industry compliance standards

    • REACH Annex XVII for plasticizer substances
    • US FDA CFR 21 177.2600 – Polymers for food contact
    • ISO 9001:2015 for continuous production QC
    • DIN EN 71-3 for toy and childcare articles

    Typical usage ratio

    • 1–1.1 molar equivalents in octyl ester formation
    • Plasticizer level 10–30 phr (parts per hundred resin) in PVC blending, adjusted based on flexibility specification

    Downstream process integration

    • Introduced into high-shear reactors for plasticizer synthesis; products then blended into PVC or co-polymer melt-in extrusion and film calendaring lines

    Final product types

    • PVC films and sheets for packaging
    • Flexible cable compounds
    • Automotive interior trim polymers

    5. Fine Chemical Synthesis for Electronic Chemicals

    Electronics manufacturers and fine chemical integrators employ this alcohol in preparing chiral ligands and intermediates for liquid crystal formulations. Its key role involves forming esters and other derivatized products where chirality impacts optical purity and device performance, such as in high-resolution LCDs or OLED displays. Controlled process environments and high-purity input are essential for reducing defects in downstream patterning or deposition.

    Industry compliance standards

    • IEC 62474 for declarable substances in electrical/electronic products
    • RoHS Directive 2011/65/EU – Restriction on hazardous substances
    • IATF 16949 for electronic materials traceability
    • Customer-specific contaminant < 10 ppm limits

    Typical usage ratio

    • 1 molar equivalent in ligand or ester synthesis; final additive dosage set by optical property tuning (typically 0.05–0.15% in LC material mixes)

    Downstream process integration

    • Charged into esterification or ligand synthesis reactors; downstream purification and blending with nematic or smectic base materials before injection or cell assembly

    Final product types

    • Liquid crystal panel formulation additives
    • OLED display precursors
    • High-purity chiral fine chemicals
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    Certification & Compliance
    More Introduction

    L(-)-2-Octanol: Quality Direct from the Manufacturer

    Relying on Our Own Experience

    Producing L(-)-2-Octanol in our own facility gives us an inside view on what customers expect and what real consistency means for industries relying on this specific alcohol. For those who use chiral alcohols in synthesis, the margin for deviation is razor-thin. L(-)-2-Octanol, also known as (S)-2-Octanol, has specific value because enantiopurity matters.

    Every step from sourcing raw materials to packing the finished bottles draws on lessons we've learned batch after batch. Years back, initial production required constant yield-verification runs—yield fluctuations forced us to fine-tune our catalytic hydrogenation process. By focusing on both chemical yield and optical purity, we found how trace metals, humidity, and even drum storage length affected quality. Each lot we ship now comes with years of iterative improvement tied to it, and nobody learns those lessons faster than those of us on the factory floor.

    Specifications and Physical Properties

    Our L(-)-2-Octanol generally exceeds 98% enantiomeric excess. The colorless, transparent liquid features a boiling point around 179-181 °C and a faint characteristic odor that signals its freshness. Storage in stainless steel or HDPE drums helps us keep impurities below 0.5%. Consistent purity turns out to be non-negotiable for our pharmaceutical and fragrance partners—just a trace of the racemic or R-isomer can mean unpredictable outcomes downstream.

    Moisture control stays on our checklist—drying the alcohol reduces risk for hydrolysis during Grignard or coupling reactions. We measure water content using Karl Fischer titration onsite and target below 0.1%. Alkali or other residues never leave our reactors; we use both manual and in-line monitoring because even invisible amounts show up later in Fourier-transform infrared spectroscopy. We only ship after chromatograms confirm both chemical and optical purity.

    Applications Shaped by End-User Needs

    Manufacturers of active pharmaceutical ingredients demand L(-)-2-Octanol that's free of color-bodies and side-products. Many use this alcohol to introduce chirality in intermediates or to build complex molecules for drug research. This is where our vertical integration provides manufacturers a safety net—when a partner’s chemist calls about an unscheduled pilot run, our inventory and lab support cut turnaround time. Batch traceability isn’t optional here—clients track raw material source, intermediate handling, and transportation.

    Our technical team has worked side by side with process developers scaling up from gram to multi-ton volumes. In one case, a partner’s unexpected surge in demand meant overnight lab analysis and tanker delivery. No amount of digital paperwork substitutes for picking up the phone, checking the drums yourself, and listening to what a line operator says about an unusual odor. The fragrance sector also values our consistency, especially when L(-)-2-Octanol forms part of a key perfumery note. Quality lapses translate directly to finished product recalls.

    What Differentiates L(-)-2-Octanol from Other Products

    One key distinction lies in stereochemistry. Racemic 2-octanol blends both L(-) and D(+) forms, but for asymmetric synthesis, only one enantiomer fits. We learned early that controlling chirality isn’t about switching out a catalyst and walking away—it takes a dedicated reactor line and vigilant staff who catch the smallest deviations. Even now, occasional requests come in for the D(+) isomer or racemate, but most research and production targets the pure L(-) form due to its selectivity in downstream synthesis.

    Comparing to 1-octanol or other secondary alcohols brings out the differences in boiling point, polarity, and reactivity. L(-)-2-Octanol balances hydrophobic and hydrophilic traits, which helps solvency profiles. Storage and handling vary too—2-octanol’s lower freezing point keeps it liquid in colder environments, minimizing solidification issues seen with longer-chain alcohols.

    Pricing structures reflect the difficulty of enantiopure production. We take no shortcuts in preparation or separation; column resolution, optically active precursors, and in-process controls all compound to make L(-)-2-Octanol a premium item. Yet, that premium prevents lost batches, saves clean-up costs, and ensures a predictable downstream process. Clients with generic processes can sometimes substitute racemic or mixed alcohols. Innovators don’t risk it.

    Process Reliability Gained Over Time

    We run dedicated production lines for our chiral alcohols. Over the years, valve upgrades and sensor additions caught quality problems before they caused any downstream failures. Maintenance teams set up regular checks that go beyond paperwork audits. At one point, feedback from an overseas batch flagged a minor off-odor. Running the GC/MS in-house brought out a trace impurity—tweaks to vapor-phase drying, plus cleaning of an underused tank, solved it for future runs.

    Container integrity counts as much as process stability. Shifting from metal to HDPE drums for export business gave us longer shelf lives and no corrosion. Each barrel ships with a batch certificate; we store backup samples at controlled temperatures to confirm shelf integrity if any issues are reported. In markets where goods sit at port for days, this reliability stops loss claims before they start.

    Practical Handling and Storage

    End-users often ask about best practices with L(-)-2-Octanol. We recommend storing at 15-25 °C, ideally in dry, well-ventilated areas. Metal containers can pick up trace ions that impact reactions, so we switched to food-grade HDPE drums for sensitive sectors. Workers appreciate having a clear loading protocol—partial drums get resealed, not just covered. Our site’s climate-control systems mean every drum leaves with minimal water content, a detail that labs notice when running moisture-sensitive syntheses.

    Operators performing drum transfers and line cleaning stick to protocols developed after more than a decade of feedback. We provide actual filling weights, not just volume estimates, because specific gravity shifts with each batch and temperature controls. This transparency means fewer questions at point of use, and no surprise density adjustments for automated feed systems.

    Regulatory Standards and Documentation

    Compliance with global standards does more than clear customs—it stops avoidable delays and keeps product claims reliable. L(-)-2-Octanol production aligns with the relevant pharmacopoeia monographs when requested, and our in-house documentation gives regulators, partners, and auditors what they need. Certificates of analysis include chiral purity, batch number, and spectroscopic data, not just basic ID and content. Some clients have asked for impurity profiling on top of our main reports; we’ve developed procedures that stretch our in-house analytics, sourcing external labs when specialist methods are needed.

    Our safety and handling guidance draws from incident analysis, practical operator reviews, and updated chemical hazard communication. Training programs focus on transfer, spill response, and waste handling. Safety data sheets undergo annual reviews to reflect both regulatory and real-world handling changes; updates go out with shipments and by email so nobody misses an update. New employees shadow experienced workers to understand why we stress personal protective equipment and immediate cleanup for even small spills.

    Learning from Industrial Collaborations

    Some of our knowledge doesn’t fit into flowcharts or compliance forms. Over coffee breaks with plant engineers and site visits with process chemists, we see shared issues surface—reaction bottlenecks, scale-up snags, or market shortages. By being the source, our role includes troubleshooting alongside partners. In one collaboration, an unexpected side reaction during esterification led to days of back-and-forth analysis. Our technical team duplicated the client’s process at pilot scale, found the impurity source, and provided an adjusted purity spec tailored to the downstream need.

    We do not just run off-the-shelf batches. Custom requests sometimes require us to hold intermediate stocks, delay shipments to match a project timeline, or even experiment with new packaging styles. Having control over production supplies lets us adjust lot sizes and delivery schedules. Distributors rarely see this kind of flexibility—being the manufacturer means we manage risk end to end. Our philosophy values these direct conversations more than bulk metrics or anonymous survey feedback.

    Environmental Responsibility and Waste Management

    Producing specialty alcohols with real care builds up a waste stream with its own management demands. Early in our operation, overhead costs came down when we optimized distillation residues and solvent recovery. No waste water heads out untreated; our treatment plant’s ammonia and hydrocarbon monitoring helps us show, not just claim, safe disposal. Any off-spec batches recycle into internal fuels or get repurposed for R&D, not dumped on the open market.

    We participate in local waste exchanges and encourage users to bring back empty drums for reprocessing. Energy usage stays under a continual improvement lens. Even slight improvements in heat recovery or insulation—identified during winter downtime—add up, reducing both environmental and cost impact. Our environmental records are open to audit for any business partner who asks.

    Opportunities in Research and Synthesis

    Research labs keep reaching for chiral building blocks like L(-)-2-Octanol because they open so many synthetic doors. Making fine chemicals, intermediates for APIs, or new agrochemicals often gets held up on stereochemistry—one wrong isomer adds weeks to a project. By holding true to a single-enantiomer pathway, we speed up not just our plant but innovation in other sectors.

    Being an active partner in research procurement means fielding last-minute spec changes or handling samples for early-stage projects. We provide small pack sizes alongside ton quantities, bridging the lab-to-pilot gap. Researchers appreciate quick feedback and the ability to ask technical questions directly; they trust us to know not just how L(-)-2-Octanol behaves but how variations affect their own reactions.

    Challenges and Developing New Solutions

    No specialty chemical line runs trouble-free for long. Raw material price swings, regulatory changes, and evolving downstream needs force us to adjust. During supply disruptions for key precursors, we tapped backup sourcing networks and accelerated raw material testing. Staff experience let us adapt plant schedules and keep customers supplied.

    We work closely with analytical chemists to predict (and prevent) common off-spec issues. The freedom to adjust purification steps and add on-the-fly quality controls gives us a buffer against unplanned disruptions. We maintain open communication with all internal staff—operators, engineers, and logistics—so critical feedback gets acted on quickly, not lost in a reporting system.

    For customers, this means steadier supply, fewer stockouts, and transparency on both intermittent hiccups and long-term plans. By sharing our own pain points and involving partners in improvement cycles, we build trust and lasting business.

    Future Outlook and Ongoing Innovation

    We invest in continuous process upgrade—better catalysts, greener solvents, and smarter control systems. As global standards shift towards sustainable production, we are already ahead by sourcing renewable feedstocks and enhancing solvent recovery systems. Newer reactor setups minimize energy use and boost enantiopurity without sacrificing throughput.

    Our technical and commercial teams invite input from customers and researchers on new application areas. Recent requests highlighted the potential for optically pure 2-octanol in novel material synthesis and advanced coatings. Pharmaceutical advances drive new specifications; our ability to tweak processes and test in-house has led to several new product grades in just the past year.

    By keeping our commitment to process and product improvement, we offer not just L(-)-2-Octanol, but a partnership built on experience and openness. Every order and every inquiry brings a chance to improve. That’s as close to a guarantee as this business gets—for us and for those depending on our product every day.