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Isopropyl Palmitate

    • Product Name Isopropyl Palmitate
    • Alias IPPA
    • Einecs 203-751-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    658847

    Chemical Name Isopropyl Palmitate
    Cas Number 142-91-6
    Molecular Formula C19H38O2
    Molecular Weight 298.5 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Characteristic, faint odor
    Boiling Point 220°C (428°F) at 760 mmHg
    Melting Point -4°C (24.8°F)
    Solubility In Water Insoluble
    Density 0.852 g/cm³ at 20°C
    Refractive Index 1.434 - 1.438 at 20°C
    Flash Point 148°C (298°F)
    Logp 8.3
    Viscosity 11 mPa·s at 20°C
    Use Emollient in cosmetics and topical pharmaceuticals

    As an accredited Isopropyl Palmitate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Isopropyl Palmitate is supplied in a 1-liter amber plastic bottle with a tight screw cap, labeled with product and safety details.
    Shipping Isopropyl Palmitate is shipped in tightly sealed containers, typically drums or bottles, to prevent leakage and contamination. It should be stored in a cool, dry, well-ventilated area away from heat, sparks, or open flames. Proper labeling and handling in accordance with regulations ensure safe transport and storage of this chemical.
    Storage Isopropyl Palmitate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from direct sunlight, heat, and sources of ignition. Protect from moisture, oxidizing agents, and extreme temperatures. Keep the storage area clean and follow all relevant safety guidelines to prevent contamination and ensure chemical stability.
    Application of Isopropyl Palmitate

    Applications of Isopropyl Palmitate in Industrial Manufacturing

    Isopropyl Palmitate finds use as an essential emollient and processing aid across several regulated industrial sectors. As the original manufacturer, we support strict raw material traceability, continuous lot quality verification, and partnership in customer-specific qualification processes.

    1. Personal Care Formulations: Creams, Lotions, and Sunscreens

    Personal care manufacturers incorporate this raw material as a skin conditioning agent to impart a non-greasy texture with fast absorption in high-volume outputs such as moisturizing creams, body lotions, and sunscreen emulsions. Large-scale factories dose the ingredient at controlled stages to ensure consistent rheology, skin feel, and spreadability aligned with region-specific consumer demands. Compliance teams verify documentation and specification alignment based on targeted geographic markets before releasing finished batches.

    Industry compliance standards

    • EU Cosmetic Regulation (EC) No. 1223/2009
    • U.S. FDA Title 21 CFR 700.3 & 701.3
    • China National Cosmetic Safety Technical Standard (GB 7916/2015)
    • ASEAN Cosmetic Directive

    Typical usage ratio

    • 3–10% w/w in facial and body lotions, adjusted for desired emollience and formulation stability
    • 1–5% w/w in lightweight gel creams
    • 2–6% w/w in sunscreen emulsions to enhance spreadability without excessive occlusion

    Downstream process integration

    • Added during oil phase heating in vacuum emulsification lines
    • In-line blending after main oil-soluble actives for homogeneous texture development
    • Incorporation after phase inversion in continuous batch reactors for lotions and creams

    Final product types

    • Face and body creams for daily moisturizing
    • SPF-rated sunscreen emulsions
    • After-sun lotions and milks
    • Hand and foot repair balms

    2. Pharmaceutical Semisolid Preparations: Ointments and Topical Gels

    Pharmaceutical producers apply the raw material for its excipient role in dermal delivery systems. Its well-documented safety profile, mildness, and ability to modulate solvent properties allows high API dispersion, improved dermal penetration, and stability of semisolid bases. Extensive in-house QC ensures batch-to-batch consistency matching submitted CTD dossiers for global regulated markets. Pharmacopoeial controls cover identity, purity, and impurity profiles.

    Industry compliance standards

    • United States Pharmacopeia (USP-NF monographs for pharmaceutical excipients)
    • European Pharmacopoeia (Ph. Eur.) 9.0
    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • WHO GMP guidelines for pharmaceutical production

    Typical usage ratio

    • 5–15% w/w in semisolid ointment bases
    • 3–8% w/w in topical medicated gels, adjusted for viscosity and release profile as per project requirements

    Downstream process integration

    • Included in initial lipid phase melting before API or actives addition
    • Blended with other penetration enhancers to fine-tune drug delivery characteristics
    • Premixed with auxiliary excipients (e.g., surfactants) prior to emulsification for uniformity

    Final product types

    • Topical corticosteroid ointments
    • Antifungal and antibiotic creams
    • Hormonal transdermal gels
    • Dermatological emollient bases

    3. Industrial Lubricants and Release Agents: Plastics and Rubber Processing

    Major plastics and elastomer processors use Isopropyl Palmitate as an internal and external lubricating agent to reduce friction, aid demolding, and improve flow characteristics of polymer melts during injection molding and extrusion. Its chemical stability and compatibility with a range of thermoplastics and elastomers support its adoption in settings requiring compliance with technical grade specifications and controlled residual profiles in final molded goods. QC teams routinely test lot homogeneity and compatibility in pilot-scale compounding prior to main cycle runs.

    Industry compliance standards

    • ASTM D1238 Melt Flow Rate specifications for polymers
    • ISO 9001:2015 QMS requirements for industrial lubricant suppliers
    • Internal automotive OEM material approval protocols
    • REACH (EC) No. 1907/2006 SVHC disclosure for additives

    Typical usage ratio

    • 0.5–2.0% w/w in plastics extrusion and injection molding batches
    • 0.2–1.5% w/w in rubber compounding as a process aid
    • Adjusted based on matrix viscosity, die design, and required surface finish

    Downstream process integration

    • Direct addition to polymer or elastomer blends during melt blending
    • Metered feeding into the barrel zone of extruders or injection molding equipment
    • Co-blending with other internal and external release agents based on product geometry

    Final product types

    • Automotive and appliance plastic housings
    • Thermoplastic elastomer gaskets and seals
    • Injection molded consumer goods
    • High-performance cable and wire insulation coatings

    4. Food Packaging Films: Anti-Sticking and Slip Additives

    Food-grade flexible packaging manufacturers deploy Isopropyl Palmitate as a slip and anti-blocking additive in polyolefin and biopolymer film extrusion. This application reduces tackiness, eases film unwinding, minimizes blockage during high-speed roll-to-roll conversions, and enables sandwich lamination. Adherence to food contact purity requirements, traceability documentation, and migration limit testing form an integral part of downstream process controls.

    Industry compliance standards

    • EU Regulation No. 10/2011 on plastics for food contact
    • US FDA 21 CFR 177.1520 (olefin polymers for food contact)
    • Japan Food Sanitation Act for food packaging additives
    • EN 1186 migration and extractables testing protocols

    Typical usage ratio

    • 0.1–1.0% w/w in polyethylene and polypropylene film masterbatches
    • 0.2–0.8% w/w for direct blending in cast and blown film extrusion
    • Adjusted according to gauge thickness and downstream printability requirements

    Downstream process integration

    • Masterbatch compounding under nitrogen to prevent oxidative degradation
    • Pre-mixing with polymer pellets before extrusion intake for homogeneous distribution
    • Added inline before film cooling and take-up stages in high-throughput extrusion lines

    Final product types

    • Primary flexible food wraps
    • Resealable bag and pouch films
    • Laminated bakery packaging films
    • Deli and produce tray liners

    5. Parenteral Medical Devices: Hydrophobic Coatings and Encapsulants

    Producers of disposable medical devices utilize this excipient in component coating and encapsulation to modulate surface lubricity and water resistance without compromising device integrity. Device engineers tweak the material content in line with biocompatibility assessments and device shelf-life targets. Cross-departmental validation covers process residuals, extractables, leachables, and physiochemical interaction screening per Class I and II medical device requirements.

    Industry compliance standards

    • ISO 10993-1 evaluation for biocompatibility of medical devices
    • USP Class VI biological reactivity tests
    • 21 CFR 820 Quality System Regulation for device manufacturers
    • IEC 60601-1 safety standard for medical electrical equipment coatings

    Typical usage ratio

    • 0.5–3% w/w in hydrophobic surface formulations
    • 1–4% w/w for encapsulant blends, adjusted in pre-production trials for coating uniformity

    Downstream process integration

    • Roll-coating of device housings and insert molds
    • Dip-coating of reservoir and tubing components before sterilization
    • Incorporation in pre-polymer mixes for overmolded device panels

    Final product types

    • Pre-filled injection device housings
    • Disposable IV catheter tubes
    • Test strip casings and diagnostic device covers
    • Protective encapsulants for sensor electronics
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    Certification & Compliance
    More Introduction

    Isopropyl Palmitate: A Manufacturer’s Perspective on Quality, Purpose, and Difference

    Understanding Isopropyl Palmitate in Industry Practice

    Isopropyl palmitate, known throughout the world of ingredient manufacturing as a trusted emollient and skin conditioning agent, has built its reputation based on reliability and performance. As a manufacturer with years of hands-on experience, we have worked directly with the raw materials, witnessed production runs from start to finish, and observed firsthand how process variables affect purity and functional characteristics. We understand the nuances behind each batch and the impact of specification choices on finished product behavior.

    The substance itself combines isopropyl alcohol and palmitic acid derived from palm oil. Its chemical structure, C19H38O2, gives it an ideal balance of mildness and spreadability. We have refined manufacturing conditions over time to ensure minimal impurities, consistent color, a low acid value, and an odor profile that meets cosmetic benchmarks. Through hundreds of batches, we have seen how purity—or lack of it—shows itself not only in lab analysis but also in downstream formulations. Real-world feedback from customers shapes the improvements we continue to make at the factory floor.

    Physical Properties: Defining What Matters

    The distinction of our isopropyl palmitate comes not from vague claims but from measurable details. This ester appears as a clear to pale yellow, oily liquid at room temperature. Viscosity tends toward the thinner side of the emollient spectrum, supporting rapid absorption and a non-greasy feel. There is no cloudiness when stored and handled at standard conditions; the absence of haze matters for formulating transparent lotions and serums.

    In our plant, control over the acid value and saponification value sets the standard for stability and compatibility. Years of data confirm an acid value under 0.5 mg KOH/g, and a saponification value typically falls within the range of 205-220 mg KOH/g. These parameters, monitored every shift, are part of our routine quality checks because minor deviations can shift the odor, change reactivity with other cosmetic actives, or even affect shelf-life.

    Why Producers Choose Isopropyl Palmitate

    Isopropyl palmitate finds its way into an impressive range of products, old and new. As an ingredient manufacturer, our primary buyers include large-scale skin care formulators, personal care brands, and pharmaceutical developers. Its longstanding appeal boils down to its sensory profile: this ingredient provides a lubricious feel, easy ‘slip’ on the skin, and enhances spreadability whether in lotions, creams, or makeup removers.

    We’ve watched trends come and go, but demand for consistency never fades. Customers in the cosmetics industry rely on isopropyl palmitate because it supports light textures without the heavy residue associated with some emollients. We’ve tested it in-house across sunscreen, baby oil, and face moisturizer prototypes and seen repeatable improvement in the tactile finish. Since it is non-polar, it readily dissolves many types of sunscreen actives and pigments—an advantage for laboratory-scale innovation and high-speed manufacturing alike.

    Another feature, often overlooked until something goes wrong, is compatibility. Our routine collaboration with customers has reinforced the value of an ester that neither disrupts emulsions nor reacts unfavorably with actives. This holds especially true for anhydrous balms or clear formulations. There are very few reports of allergic response, which appeals to producers aiming for hypoallergenic products.

    Comparing Isopropyl Palmitate with Other Emollients

    Manufacturers do not make ingredient decisions in a vacuum. We have run side-by-side tests with other fatty esters such as isopropyl myristate, caprylic/capric triglyceride, and mineral oil, each presenting its benefits and drawbacks. Isopropyl palmitate distinguishes itself through its medium molecular weight, lending it a lighter feel than myristate but richer consistency than short-chain esters.

    In practice, isopropyl myristate often gives a slightly faster absorption but sometimes causes a drying sensation over time. In contrast, isopropyl palmitate offers a cushiony after-feel that formulators frequently tie to user satisfaction. Compared to mineral oil, isopropyl palmitate avoids the petrochemical origin and greasy texture. Caprylic/capric triglyceride, another plant-based emollient, works well for the fast-absorbing segment but can ‘thin out’ certain products more than desired. Through all these comparisons, customers tend to come back to isopropyl palmitate when seeking balance: softness without residual stickiness, solvency without risk to stability, and sensory attributes that please a broad range of end-users.

    Specifying Quality: From Raw Material to Shipment

    Our facility begins with rigorous checks on raw materials. Not all palm-derived palmitic acid sources behave identically. Through direct sourcing relationships, we request full traceability and require suppliers to demonstrate pesticide and contaminant control. We test for residual isopropanol, as any left can alter odor and safety, and we commit to levels below recognized industry thresholds.

    Our standard batches of isopropyl palmitate follow specifications tailored through close consultation with R&D partners and production teams. Most parameters do not shift appreciably yield after yield, as steady process temperature and reaction time are crucial. Typically, water content remains under 0.1%, and the product’s reactivity stays controlled for at least two years after manufacture. Documentation supports every drum, and we store under inert conditions until shipment to rule out oxidation.

    Some buyers request products conforming to more tailored specifications—color grade, acid value, or a certification for natural origin. We accommodate those requests as our equipment allows, balancing flexibility with cost efficiency. Experience reminds us that if characteristics wander from agreed specs, minor issues turn into expensive recalls and downstream instability. Every drum that leaves our warehouse carries a batch record; every batch shows the work of teams trained to spot and resolve deviations before they reach customers.

    Sustainability and Traceability: Changing Demands

    Markets for isopropyl palmitate have changed. Sustainability in sourcing and processing no longer exists just as an optional add-on. Many customers, especially in Europe and North America, seek certification that raw palm sources do not contribute to deforestation or violate fair labor standards. Years ago, these questions rarely reached the manufacturing desk; today, most contract discussions include documented proof of supply chain sustainability.

    We have integrated traceability practices on the raw material side, from close monitoring of Certificates of Analysis to periodic supplier audits. We support certified sources when possible, though supply chain challenges create periodic shortages. We advise our buyers to plan orders ahead to ensure traceable, responsibly produced product can be delivered even during periods of surging demand or logistical disruption.

    Many synthetic alternatives may offer price or performance edges for certain uses, but bio-based solutions—of which isopropyl palmitate stands as one—carry consumer trust in sectors focused on green labeling. As a supplier, we continue to push for clarity at all stages, from field to reactor vessel, believing that transparent traceability supports lasting business partnerships.

    Regulatory Compliance and Consumer Expectations

    Tighter regulation and higher consumer awareness have defined the modern landscape for isopropyl palmitate. Ingredient transparency, INCI listing accuracy, and allergen labeling often form key parts of our customers’ audits. Our documentation system tracks every input, every operator, and every adjustment; this level of detail supports rapid answers to technical queries and regulatory inspections alike.

    European REACH registration defines our benchmark for safe handling and downstream use. We ensure compliance with current cosmetic regulation (such as Regulation EC 1223/2009), and provide standardized Safety Data Sheets so our partners can incorporate isopropyl palmitate with confidence. In North America, the substance carries GRAS status for indirect food contact; every declaration aligns with U.S. FDA and Health Canada recommendations. Over the years, we have found that full traceability and up-to-date compliance documents mean fewer questions at customs and fewer delays in customers’ own submissions.

    Practical Use: Working With Isopropyl Palmitate on the Manufacturing Floor

    From a technical perspective, formulating with isopropyl palmitate offers straightforward handling. Its liquid form eliminates the need for heating beyond ambient temperature for most applications, simplifying process design and reducing batch turnaround time. We have observed that this ester dissolves common cosmetic actives, such as UV filters and retinoids, more readily than heavier oils. This quality speeds up dissolve times in production, trims batch variability, and supports rapid product scale-up.

    Cleaning equipment after isopropyl palmitate runs requires less detergent than after using mineral oil or heavy esters. We do not see stubborn residues or color carryover. The neutral odor profile, always confirmed with batch release, lets fragrance houses craft signature scents without masking or distortion. From our own pilot-scale work, we have learned that unexpected incompatibilities occur less frequently with isopropyl palmitate than with shorter or more reactive esters.

    Performance Feedback: What Customers Report

    Feedback shapes what we make and how we improve. Over the years, customers have reported faster absorption and a smoother glide in finished lotions compared to other esters. In wipe-off cleansers, isopropyl palmitate helps dissolve stubborn makeup without heavy film left behind. Manufacturers of anti-aging lines often highlight the ‘cushion effect’—an enduring softening sensation reported by testers even after several hours.

    Production managers value fewer line stoppages, less ingredient separation, and reduced waste during tank transfer. In larger operations where margin pressures increase scrutiny, the ability to work with a product that remains stable for months after processing stands out. Based on routine customer visits, it’s clear that formulation teams spend less time troubleshooting separation or graininess compared to working with more volatile or low-purity emollients.

    Addressing Typical Challenges

    No ingredient answers all needs. We have observed that isopropyl palmitate does not provide strong film formation or occlusivity, so it does not work as a direct substitute for petrolatum or heavier natural butters in barrier creams. Customers pursuing pronounced ‘lock-in’ effects sometimes pair it with waxes or occlusive esters to build a layered formula. The molecule’s modest polarity means it dissolves most lipophilic actives, but can lag with highly polar or ionic components.

    Storage stability rates as good when managed correctly. Under prolonged exposure to air or light, some batches may oxidize and develop off-odors. Our updated packaging design—drums lined with protective coatings and filled under nitrogen—addresses most of these concerns. End-users storing product for more than a year, especially outside temperature-controlled spaces, should draw from recent batches to avoid shifts in color or odor. These issues rarely occur with proper inventory rotation, and good planning between manufacturer and buyer mitigates almost all risk.

    Safety, Handling, and Worker Confidence

    Production teams benefit from confidence in safety routines. Isopropyl palmitate rates as non-irritating to skin under normal working concentrations, and does not require special respiratory protection beyond standard factory PPE. We instruct workers to avoid contact with eyes and open wounds, and we emphasize proper storage alongside other non-aqueous, flammable liquids. Flash point, well above room temperature, supports safe storage and shipping without elaborate precautions. We invest in routine hazard training, but rarely encounter safety incidents related to this material.

    In case of major spill, clean-up requires little more than absorbent materials and standard waste handling—significantly simpler than with many solvents or strong acids used in industry. We encourage customers to review their handling protocols with us, as site-level safety often varies with batch size, geography, and cross-contamination risk. With straightforward labeling and minimal hazard pictograms, workers show confidence in handling, and factory audits pass without corrective action on this front.

    Future of Isopropyl Palmitate Manufacturing

    The market for isopropyl palmitate continues to evolve. Emerging trends toward vegan, palm-free, or biodegradable formulations push us to explore new routes for palmitic acid sourcing, including options from upcycled and alternative plant oils. The technical challenge remains to deliver the same functional properties with new raw material streams. Early pilot trials suggest that with careful process adjustments, alternative sourcing can match classic palm-based material nearly one-for-one for texture and purity.

    Regulations around palm sustainability and traceability will grow tighter. Our experience reinforces the need for clear documentation, adaptable procurement, and regular engagement with suppliers. Forward-looking brands now want ingredients that not only perform but support stories of responsible sourcing and reduced ecological footprint. We expect more direct collaboration with brands on ingredient transparency, helping them differentiate their products without compromising quality.

    Product innovation does not rest only with the end-users. In recent years, we have partnered with clients looking to build combinations—such as blends of isopropyl palmitate with volatile silicones, natural waxes, or other light esters—to construct unique textures or improve performance in challenging climates. On the technical side, our R&D staff keeps improving process controls and product consistency, driven by both regulation and the relentless competition in global manufacturing.

    Our Ongoing Commitment

    Each year, we examine both customer requests and technical process data to identify areas for continued improvement. We focus on reproducibility, traceability, and tailored support for new formulations. As customer trends shift toward specialty applications—OTC topical drugs, wipes, waterless formulations, and slow-release actives—we adapt our own models for quality checks and product sample testing.

    We invest in lab-scale and pilot-run capabilities so customers can try before committing to large orders. Batch history, process certification, and a technical support team come as part of every shipment. Our business partners count on fast resolution of questions and customized logistics planning, especially for sensitive uses or niche market launches.

    Isopropyl palmitate continues to stand out for its ease of use, balanced sensory impact, and compatibility with modern trends in cosmetics and personal care production. Our perspective as direct manufacturers gives us a clear view of what makes this ingredient a staple, where customers benefit most, and how we can improve support in the years ahead.