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Iodotrifluoroethylene

    • Product Name Iodotrifluoroethylene
    • Alias Trifluoroiodoethylene
    • Einecs 206-982-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    225137

    Chemicalname Iodotrifluoroethylene
    Molecularformula C2F3I
    Molarmass 207.92 g/mol
    Casnumber 359-11-5
    Appearance Colorless gas
    Boilingpoint 0.5 °C
    Density 2.34 g/cm³ (at 20 °C)
    Solubilityinwater Slightly soluble
    Refractiveindex 1.328 (at 20 °C)
    Meltingpoint -110 °C
    Vaporpressure 740 mmHg (at 20 °C)

    As an accredited Iodotrifluoroethylene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Iodotrifluoroethylene is packaged in a 100g dark amber glass bottle with a secure cap, labeled with hazard warnings and details.
    Shipping Iodotrifluoroethylene should be shipped in tightly sealed containers under an inert atmosphere, such as nitrogen, to prevent decomposition. It must be stored and transported as a hazardous material, following all relevant local and international regulations, including proper labeling and documentation. Handle with care to avoid exposure, heat, sparks, or open flames.
    Storage Iodotrifluoroethylene should be stored in a cool, dry, well-ventilated area, away from heat, sparks, and open flames. The container must be tightly sealed and kept in a secure location to prevent leakage. Store away from incompatible substances such as strong oxidizers and bases. Proper chemical labeling and secondary containment are recommended to minimize risk in case of accidental spillage or leakage.
    Application of Iodotrifluoroethylene

    Applications of Iodotrifluoroethylene in Industrial Manufacturing

    Iodotrifluoroethylene serves as a high-value intermediate for a range of industrial synthesis routes, driven by its unique halogenated structure and reactivity profile. As the direct manufacturer, we support advanced process integration in several specialized markets, enabling downstream producers to meet stringent compliance and deliver functional end products.

    1. Fluorinated Elastomer Precursor for Chemical Process Equipment

    Major fluoropolymer producers use iodotrifluoroethylene as a building block for specialty fluoroelastomers. Its three fluorine atoms and reactive iodine site offer controlled incorporation during copolymerization, resulting in elastomeric chains with precise fluorine content, enhanced chemical resistance, and mechanical flexibility. This balanced performance is critical for seals, gaskets, and linings exposed to acids and aggressive solvents in high-purity chemical processing environments.

    Industry compliance standards

    • ASTM D1418 (Rubber and Copolymer Classification)
    • ISO 9001:2015 (Quality Management in Production)
    • UL 157 (Elastomeric Compounds for Industrial Equipment)
    • REACH Regulation (EC) No 1907/2006

    Typical usage ratio

    • 5–20% by monomer ratio, typically adjusted for targeted polymer backbone properties and process requirements.

    Downstream process integration

    • Introduction during emulsion or solution copolymerization alongside TFE or vinylidene fluoride, with staged addition to control molecular weight and block structure.

    Final product types

    • Chemical-resistant O-rings
    • Valve seat materials
    • Flexible pump diaphragms
    • Specialty chemical plant hose liners

    2. Pharmaceutical Intermediate Synthesis for Active Fluorinated Molecules

    Iodotrifluoroethylene is a key starting material for the construction of advanced fluorinated motifs in pharmaceutical actives. Its halogenated vinyl structure enables selective coupling, cross-coupling, and addition reactions, especially in the synthesis of trifluorovinyl-containing active pharmaceutical ingredients (APIs). These fluorinated fragments contribute to drug molecule bioavailability, metabolic stability, and improved receptor binding. Our material undergoes rigorous quality control, supporting downstream manufacturers demanding high-purity standards for regulated pharma synthesis.

    Industry compliance standards

    • ICH Q7 (GMP for Active Pharmaceutical Ingredients)
    • USP-NF (United States Pharmacopeia—National Formulary) monographs on fluorinated intermediates
    • 21 CFR Part 210/211 (Current Good Manufacturing Practice)
    • European Pharmacopoeia 11.0

    Typical usage ratio

    • 0.1–2.5 molar equivalents in key coupling steps, with adjustment based on targeted API structure and downstream reaction efficiency.

    Downstream process integration

    • Direct introduction in stepwise synthesis for cross-coupling (e.g., Suzuki or Sonogashira reactions) or nucleophilic addition, under inert atmosphere and controlled temperature to minimize side reactions.

    Final product types

    • Fluorinated anticancer drug intermediates
    • Fluorine-rich antivirals and CNS actives
    • Fluorinated diagnostic probes (PET tracers)
    • API fragments for structure-activity optimization

    3. Agrochemical Intermediate in Selective Herbicide and Insecticide Synthesis

    Manufacturers in the crop protection sector select iodotrifluoroethylene for its reactivity in crafting highly selective fluorinated agrochemicals. Its unique iodine and trifluoromethyl functionalities allow for rapid, efficient incorporation into active moieties that demonstrate high activity and low environmental persistence. Proper handling and integration into multistep synthesis streams ensure residues are minimized and compliance with agrochemical registration is maintained.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals (Synthesis Purity and Residuals)
    • ISO 17025 (Testing and Calibration in Agrochemical Labs)
    • EU Regulation (EC) No 1107/2009 (Authorization of Plant Protection Products)
    • EPA FIFRA Compliance (40 CFR Part 158)

    Typical usage ratio

    • 0.5–5% by mass of stepwise intermediates, optimized based on desired selectivity index and synthetic route constraints.

    Downstream process integration

    • Applied during key halogenation or trifluoromethylation stages, with process control measures for safe handling and minimization of byproduct formation in batch reactors.

    Final product types

    • Trifluorovinyl-substituted herbicide actives
    • Selective insect control agents
    • Low-residue agrochemical formulations
    • Seed-treatment ingredients with enhanced uptake

    4. Specialty Surface Modification for Electronic Materials

    Iodotrifluoroethylene is used in the electronics industry for introducing fluorinated vinyl groups onto polymer substrates or silane coupling agents, granting high dielectric strength and reduced surface energy. This application targets high-frequency insulators, printed circuit board coatings, and specialty encapsulation resins, where stable C–F bonding ensures insulation reliability under varying environmental and operational stress. Manufacturers achieve functionalization through controlled addition reactions and surface grafting techniques.

    Industry compliance standards

    • IPC-4101 (Base Materials Standard for Rigid and Multilayer PCBs)
    • IEC 60216 (Electrical Insulating Materials—Thermal Endurance)
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances)
    • ISO 14001 (Environmental Management for Electronic Material Suppliers)

    Typical usage ratio

    • 1–8% by weight in surface-functionalization steps; ratio adjusted by the required dielectric properties and thickness of applied fluorinated layers.

    Downstream process integration

    • Graft copolymerization onto polymer backbones, or vapor-phase addition on dielectric films near the finishing stage to impart hydrophobicity and electrical resistance.

    Final product types

    • PCB protective coatings
    • Dielectric encapsulation compounds
    • Hydrophobic wire insulation films
    • Flexible electronic packaging

    5. Fluorinated Monomer Source for High-Performance Coatings

    Downstream coating formulators use iodotrifluoroethylene as a monomer for synthesizing fluorinated acrylics and specialty copolymers. The resulting coatings display high UV resistance, low surface tension, and substantial anti-fouling properties required for outdoor and marine substrates. Its reactivity ensures efficient grafting and short reaction times in pilot and large-scale reactors, producing coatings compliant with environmental and performance benchmarks.

    Industry compliance standards

    • ASTM D5402 (Solvent Rub Resistance of Organic Coatings)
    • ISO 12944-6 (Paints and Varnishes—Protective coatings systems for structures)
    • EPA 40 CFR Part 63 (NESHAP for Surface Coating Operations)
    • VOC Emissions Control Regulations (regional/local)

    Typical usage ratio

    • 2–10% by monomer feed; levels controlled according to weather resistance and film-forming requirements.

    Downstream process integration

    • Fed into reactor with base acrylate or methacrylate monomers at initiation, followed by copolymerization under thermal or photoinitiated conditions to ensure even fluorine distribution.

    Final product types

    • Marine anti-fouling paints
    • Architectural UV-resistant coatings
    • Self-cleaning exterior surface finishes
    • Heavy-duty industrial flooring topcoats
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    Certification & Compliance
    More Introduction

    Iodotrifluoroethylene: A Manufacturer’s Perspective on Its Transformative Role in Advanced Chemistry

    Pushing the Boundaries of Halogenated Olefin Chemistry

    Chemical manufacturing often demands more than just raw output. Day in and day out, we meet research teams searching for specialties—compounds that go beyond basics and provide the springboard for their next process. Among the fluorinated building blocks we manufacture, Iodotrifluoroethylene (C2F3I) has become a standout for both academic and industrial innovation. Our daily operations have kept us close to the technical backbone and shifting application trends of this material, and in that time, our appreciation for its unique profile has only grown.

    The Model: Molecular Structure and What Sets It Apart

    Iodotrifluoroethylene, with a molecular structure of CF2=CFI, springs from the crossroads of iodine and strong carbon-fluorine bonds. This hybridization opens up transformation routes other ethers or perfluoroalkenes can’t touch. Our consistently produced batches meet rigorous purity standards and batch reproducibility, supporting research goals and downstream chemical synthesis. Manufacturing in controlled environments helps contain its reactive nature but also leverages its potential for rapid addition and substitution reactions. In real-life batches, the colorless, volatile liquid presents with recognizable physiochemical signatures—traits our QC chemists never lose sight of during batch release.

    Navigating Challenges: Storage, Stability, and Handling Know-How

    Every plant operator handling Iodotrifluoroethylene learns early that stability isn’t to be taken for granted. This molecule’s electron richness makes it a target for nucleophiles and a candidate for radical-initiated reactions. Older storage protocols fumbled with UV light degradation. Today, we store every drum and cylinder under nitrogen, in well-sealed, amber-coated vessels. Years of product feedback have taught us how small environmental spills and trace moisture catalyze unwanted side reactions. Not everyone understands the balance of physical conditions this compound likes, but we respond to those lessons daily—tuning our logistics for just-in-time supply and maximum integrity.

    Direct Use Cases: Why Synthetic Chemists Keep Coming Back

    Research chemists and process developers see Iodotrifluoroethylene as a strategic puzzle piece—not a generic feedstock. Thanks to the iodine leaving group, it plays a starring role in synthesis of fluorinated materials, custom pharmaceuticals, and functional polymers. A large share of our orders go to laboratories working on active ingredients, but scale-up customers count on our production for pilot and process development. In telomerization and cross-coupling processes, the compound delivers clean fluorinated frameworks. The specificity of iodine as a handle means substitution occurs predictably, saving time in optimization runs and analytical work. Across years, we’ve noticed a surge in interest from groups working in agrochemical and specialty elastomer applications, where the trifluorovinyl moiety creates both hydrophobic and thermally stable segments in finished products.

    Comparing to Other Halogenated Ethenes: What Experience Teaches

    Fluoroalkene chemistry holds a crowded field, and many researchers might reach first for tetrafluoroethylene or vinylidene fluoride. Our experience—and the growing body of industrial literature—shows Iodotrifluoroethylene stands apart in reactivity and chemo-selectivity. Tetrafluoroethylene tends toward more drastic polymerization and narrower compatibility in certain metal-catalyzed transformations. Chlorotrifluoroethylene brings its own batch of corrosion-handling concerns and byproduct complexity. Iodotrifluoroethylene allows for more measured, controlled addition to nucleophiles, including stepwise functionalization for complex molecules.

    We field routine questions about differences in reaction times, yields, and downstream purification. Iodotrifluoroethylene often shortens synthetic pathways since the substituent iodine atom makes it easier for chemists to build new carbon-carbon or carbon-heteroatom bonds. Fluorination is always a double-edged sword—while fluorine atoms boost chemical and thermal performance in the finished product, adding them in a way that’s useful for further work often bumps up cost and separation challenges. Our day-to-day production experience demonstrates that, despite a more involved setup for safe storage and packaging, our customers see value in minimizing steps and isolating cleaner intermediates.

    Our Manufacturing Insights: Scale-Up and Customer Support in Practice

    Scaling from gram to kilogram to multi-ton orders, repeatability matters more than any marketing description. We’ve invested in containment approaches for Iodotrifluoroethylene to prevent leaks and cross-contamination, as even trace vapor exposure can challenge indoor air systems. Years on the plant floor sharpened our approach to cylinder filling, vapor management, and product tracking. We never cut corners—every tank, every batch, tracked and tested.

    Customers in pilot-scale and up rely on direct-from-plant shipments—confidence comes from batch-to-batch consistency, supported by frequent engagement between our technical staff and their formulation chemists. The relationship isn’t transactional: it’s built on a shared pursuit of reaction reliability, quick turnaround, and continuous process troubleshooting. We get implementation feedback from multinational giants and university-based innovators alike, and every note shapes our adjustments to process or packaging for future lots.

    Industry Insights: Regulatory, Safety, and Sustainability Considerations

    Fluorochemical production carries weighty ESG duties. Iodotrifluoroethylene sits right in that crosshairs. Regulations have moved quickly in the past decade, setting benchmarks for permitted emissions and acceptable handling practices. In our operations, each kilogram comes with a legacy of environmental tracking, certified hazardous material handling, and upstream traceability. We ensure all plant operators cycle through extensive hazard control training, refreshed with every regulatory update, and we reinforce a culture where reporting even small deviations leads to plant-wide learning.

    We share environmental reporting with our stakeholders, measuring progress against lower waste generation per output ton and improved solvent recovery. The push for cleaner manufacturing is not a buzzword—it’s born from years of effluent monitoring, incident review, and process retooling at the hands of skilled operators. Customers frequently ask where we source our raw materials, how we recover byproducts, and what steps we pursue for closed-loop waste management. Every answer forms part of the trust we continuously earn with end users and regulatory bodies alike.

    Meeting R&D Demands: Supporting the Next Generation of Functional Materials

    Every year, discussions with synthetic chemists lead us to new frontiers for Iodotrifluoroethylene. Material science teams pursue innovative uses in fluorinated surface coatings, membrane science, and advanced bioactive molecules. As these fields chase better performance—higher thermal resistance, chemical inertness, precise electronic properties—Iodotrifluoroethylene opens pathways conventional unsaturated compounds can’t match.

    Our technical team works with researchers to optimize protocols, scale-up pilot batches, and troubleshoot incompatibilities. Close collaboration can shave years off the timeline for getting new fluorinated compounds from bench to operational scale. For example, developers working with perfluorinated polymers use our tailored advice on handling, storage, and process conditions, so pilot work translates to steady commercial output, without hiccups.

    Supply Chain Complexity: Lessons from Direct Experience

    Managing specialty fluorochemical supply is not a mail-order business. We’ve weathered raw material pricing swings, transportation disruptions, and tightening export controls. All that experience underscores the importance of robust in-house sourcing, logistics dedicated to temperature and moisture-sensitive cargo, and careful coordination with trusted freight partners. Each shipment draws on a network built over years, never on the fly.

    Chemical plants don’t run in isolation. Our team works regularly with regulatory partners, local environmental teams, and direct customer liaisons to prepare for audits, respond to evolving standards, and avoid bottlenecks. Without these coordinated efforts, the steady, responsive supply customers expect would break down fast.

    Beyond Commodity Chemistry: What Sets Iodotrifluoroethylene Manufacturing Apart

    Some chemical intermediates experience commodity treatment, but halogenated ethenes with high functionality skirt far from bulk trade. Each batch of Iodotrifluoroethylene reflects cumulative know-how in reaction optimization, containment, and market feedback response. The product's relatively short shelf-life, coupled with its reactivity, means every plant run is its own operation—not a mindless repetition. Our operations teams blend time-tested procedures with continuous learning, keeping us sharp and responsive. Regular plant upgrades—from improved condensation systems to real-time gas-phase monitoring—ensure safety and quality are never theoretical.

    Customers see the difference in the way their orders arrive: stable, well-packaged, labeled with relevant batch analytics, and reinforced by immediate access to our technical bench. Reluctance to hand off key steps to third parties pays dividends in customer loyalty—our relationships bear out in repeat orders and a steady trickle of technical requests that help us refine every aspect of our operation. Each feedback loop finds a way back into plant SOPs.

    Adapting to the Future: Digitalization and Advanced Analytics

    Process innovation—once driven only by bench-scale experiments—now draws on digital process control, data analytics, and real-time monitoring. Our process engineers have implemented distributed control systems that track every reactor, every fill cycle, and every outflow. Historical data lets us chart reaction yields, energy use, and even minor impurity profiles. This lets us catch quality drifts months before they become issues downstream. By sharing this information with our clients, we empower them to optimize their own use of Iodotrifluoroethylene.

    Digital systems go hand-in-hand with accountability—each audit trail, trend log, and process variable can be reviewed both internally and in regulatory review. Precision manufacturing, transparency, and reliability are not aspirational concepts—they’re lived realities enforced by both technology and culture.

    Synthesis Strategies: Practical Tips From the Plant Floor

    Not every synthetic approach works in every lab, and we’ve learned to guide users on how the reactivity of Iodotrifluoroethylene changes with batch size, pressure, and co-reactants. Where academic protocols sometimes call for small-scale glassware work, customers in scale-up settings seek our input on managing exothermic profiles, pressure equipment compatibility, and methods to manage vent gases.

    Years of customer service taught us the questions that matter most: What grade suits preparative work? What purity level eases downstream separation? Do you need pre-diluted material for safety or improved reaction control? Each answer depends on real-world demand, not a catalog spec sheet. We routinely recommend controls like remote monitoring, appropriate exclusion of atmosphere, and fast sample turnarounds for quality confirmation. This saves both material and time—resources every plant or lab needs to watch closely.

    Learning from Customer Outcomes: Lessons Returned

    Connecting with users post-purchase enriches our own technical learning. Customers working on new cross-coupling methods, next-generation fluorinated drugs, or advanced polymer composites often share performance data, which in turn sharpens our understanding of real-world challenges. The most successful partnerships are collaborative, transparent, and based on shared problem-solving. That dynamic thrives when we listen as much as we inform.

    We’ve altered plant scheduling to meet short-run experimental batches for customers trialing new synthetic series, then scaled up based on their feedback. In a landscape where innovation cycles grow shorter, agility becomes a key differentiator. We don’t just supply material—we adapt delivery, documentation, and even the fine-tuning of physical parameters to match customer needs, batch by batch.

    Global Impact and the Growing Need for High-Purity Halofluoro Compounds

    Demand for tailored fluorinated chemicals climbs steadily, not only for new drugs and catalysts, but for electronics, coatings, membranes, and specialty materials that must perform in ever-harsher environments. Iodotrifluoroethylene meets calls for greater selectivity, less process waste, and reliable functionality in applications where broader-spectrum ethenes falter. Our global customer base ranges from small biotech start-ups to established material science conglomerates, each facing its own technical hurdles. A fine balance of large-scale logistics and individualized attention sets our product apart.

    Globalization intensifies every challenge: supply chains stretch, shipping regulations change, end uses evolve. Years of direct export experience taught us to anticipate customs delays, secure appropriate filing for transport of reactive goods, and advise customers on regional handling standards. Delays and regulatory scrutiny don’t cause panic in a plant that stays up to date and keeps open communication with each relevant party.

    Staying Customer-Focused: More Than Just a Supplier

    Providing Iodotrifluoroethylene doesn’t mean pushing molecules out the door—it demands preparedness for hands-on troubleshooting and a dedication to continuous improvement. We support application development, troubleshoot analytical confusion, and advise on the entire chain from storage to use to waste. This support touches every area: shipping, documentation, customer education, technical backup, and regulatory follow-through.

    We learn just as much from customer queries as they do from our product team. That cycle of shared knowledge, practical feedback, and iterative process learning keeps us light on our feet and tuned in to shifting needs. Each request becomes an opportunity to refine both our chemistry and our service delivery. As markets mature and regulations expand, our mission stays the same: to supply a reliable, high-quality, and technologically relevant product, underpinned by direct operational experience and a willingness to share knowledge openly.

    Continuing the Journey: Serving an Evolving Chemical Landscape

    Iodotrifluoroethylene has transformed from a specialist’s curiosity to a mainstream tool for advanced synthesis, specialty polymer chains, and precise molecular engineering. Our role as the manufacturer goes far beyond traditional supply; we drive, support, and shape the entire lifecycle, from process innovation through safe and sustainable delivery to customer outcomes. Every innovation by our clients, every regulatory hurdle cleared, and every new process modeled in our pilot plant, broadens the impact of this one compound.

    Real-world chemical manufacturing demands flexibility and integrity. Each batch is an opportunity to support pioneering work in science and industry, while staying grounded in experience and responsibility. We’re proud to contribute Iodotrifluoroethylene to the continued progress of materials science, pharmaceuticals, and advanced chemical engineering worldwide. Our doors remain open for technical discussion, rapid supply, and the relentless pursuit of better results—for our customers and for the field as a whole.