Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Hydroxyecdysone

    • Product Name Hydroxyecdysone
    • Alias 20-Hydroxyecdysone
    • Einecs 217-747-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    846564

    Chemical Name 20-Hydroxyecdysone
    Molecular Formula C27H44O7
    Molar Mass 480.63 g/mol
    Cas Number 5289-74-7
    Appearance White to off-white crystalline powder
    Solubility Slightly soluble in water, soluble in ethanol and methanol
    Melting Point 242-244°C
    Applications Used as a supplement in bodybuilding, agriculture, and cosmetics
    Storage Conditions Store in a cool, dry place, protected from light
    Purity Typically available at 95% or higher
    Synonyms Ecdysterone, 20E, Beta-Ecdysone

    As an accredited Hydroxyecdysone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Hydroxyecdysone is packaged in a 25g amber glass bottle with a tamper-evident cap, labeled for scientific research use.
    Shipping Hydroxyecdysone is shipped in compliance with safety regulations, typically in sealed, chemically-resistant containers to prevent contamination and degradation. Packaging includes appropriate hazard labeling and documentation, ensuring safe transport. Temperature and light-sensitive, it may require cold packs and insulation. Shipping is coordinated via certified carriers following chemical handling protocols.
    Storage Hydroxyecdysone should be stored in a tightly sealed container, protected from light and moisture. It is recommended to keep it at a temperature of -20°C to ensure stability and prevent degradation. Avoid exposure to air and heat, and store in a dry, well-ventilated area designated for chemical storage, away from incompatible substances.
    Application of Hydroxyecdysone

    Applications of Hydroxyecdysone in Industrial Manufacturing

    Hydroxyecdysone, manufactured to consistent high-purity standards, delivers unique biochemical attributes that support targeted applications across several regulated downstream industries. This section details practical integration scenarios for Hydroxyecdysone based on its factual, established use cases, guiding professional users on compliance, formulation, and process adaptation for industrial-scale production.

    1. Pharmaceutical Active Ingredient in Nutraceutical Tablets and Capsules

    Hydroxyecdysone functions as a bioactive raw material for nutraceutical manufacturers developing oral solid dosage forms targeted at dietary supplement and sports nutrition markets. Our industrial-grade product undergoes rigorous analytical monitoring for identity and purity before blending with excipients during direct compression or granulation steps in tablet and capsule lines. Compliance with global supplement regulations restricts the addition rates and mandates traceability from batch sourcing through to finished packaging. Downstream customers require full process and material transparency for regulatory and marketing audits.

    Industry compliance standards

    • EU Novel Food Regulation (EU) 2015/2283 verification
    • US FDA Dietary Supplement Health and Education Act (DSHEA)
    • China GB 16740-2014 on health food
    • ISO 22000 and HACCP food safety management

    Typical usage ratio

    • 50 mg–250 mg per serving; standardized at 0.2%–2% by total tablet weight, varied by jurisdiction and intended claim

    Downstream process integration

    • Dry blending with direct compression or wet granulation base
    • Incorporation before blending with microcrystalline cellulose and flow aids
    • QC sampling pre-tableting and encapsulation stages

    Final product types

    • Oral dietary supplement tablets
    • Hard shell capsules
    • Chewable or effervescent supplement forms

    2. Cosmetic Active for Anti-Aging and Skin Firming Formulations

    In personal care manufacturing, Hydroxyecdysone offers scientifically recognized stimulation of collagen production and skin renewal properties, facilitating its targeted addition to face creams, serums, and eye lotions. Cosmetic formulators introduce the active during the cool-down or post-emulsification phase to preserve molecular stability. Batch records and packaging require INCI labeling and sensitivity documentation, especially in international private label and contract manufacturing scenarios aiming for cosmeceutical claims.

    Industry compliance standards

    • EU Cosmetics Regulation (EC) No 1223/2009
    • US FDA Voluntary Cosmetic Registration Program (VCRP)
    • Cosmetic Ingredient Review (CIR) safety assessment
    • Halal and ISO 22716 GMP for cosmetics

    Typical usage ratio

    • 0.1%–0.5% by weight in finished emulsions; adjustment based on skin tolerance and stability testing

    Downstream process integration

    • Addition during cool-down phase below 40°C post-emulsification
    • Homogenization with active concentrates or solubilizers
    • In-process quality testing for consistency and irritation potential

    Final product types

    • Facial creams with anti-aging claims
    • Eye serums targeting skin firmness
    • Functional sheet masks and ampoules

    3. Veterinary Feed Premix Additive for Aquaculture and Livestock

    Hydroxyecdysone enters feed additive formulations as a functional ingredient to support growth and stress tolerance in farmed aquatic species and selected livestock, used primarily in regions where functional actives are supported by local animal nutrition science. Ingredient dosing requires precision blending with vitamin or trace mineral premixes to prevent degradation and ensure even distribution throughout compound feed, with adherence to regional animal feed regulations and export quality certification. Integration hinges on coordinated QA tracking from raw material reception through finished premix blending and packaging.

    Industry compliance standards

    • European Feed Additives Regulation (EC) 1831/2003
    • China GB/T 17824.3-2008 for aquatic feed additives
    • US FDA Center for Veterinary Medicine (CVM) animal feed guidelines
    • FAMI-QS certification for specialty feed ingredients

    Typical usage ratio

    • 5–20 mg/kg in compound feed; individualized dosing based on target species, growth stage, and justification in technical dossier

    Downstream process integration

    • Micro-dosing into vitamin/mineral premix batches
    • Thorough blending prior to pelletizing or extruding feed
    • Retention testing post-processing to verify stability through heating steps

    Final product types

    • High-value aquaculture feeds (shrimp, fish)
    • Livestock nutritional supplements integrated in finished feed

    4. Botanical Extract Component for TCM/Herbal Preparations

    As a recognized monomeric constituent derived from natural plant sources, Hydroxyecdysone supports the development of Traditional Chinese Medicine (TCM) extracts and herbal granules, where controlled concentration of marker compounds is essential for batch standardization. Extract manufacturers utilize laboratory-verified raw material early in the ethanol extraction process, overseeing chromatographic fingerprinting and final quantification in standardized finished products. GMP compliance and pharmacopoeial reference remain mandatory for both export and domestic herbal markets.

    Industry compliance standards

    • Chinese Pharmacopoeia (2020 Edition), monograph standards for Cyanotis arachnoidea and Achyranthes bidentata extracts
    • Good Manufacturing Practice (GMP) for TCM production, CFDA
    • ISO 19609 for traditional Chinese medicine raw materials

    Typical usage ratio

    • Standardized to 0.5%–5% hydroxyecdysone content in final extract powder or granule, adjusted according to monograph requirements and plant source variation

    Downstream process integration

    • Addition to plant material pre-maceration or as a spike post-filtration to adjust active content
    • Defined in-process control samples and HPLC marker testing
    • Integration with carrier excipients for flow and dispersibility

    Final product types

    • Standardized herbal powders and granules
    • Herbal capsules and dispersible TCM beverages

    5. Agricultural Plant Growth Promoter for Crop Biostimulants

    Hydroxyecdysone supplies crop protection and plant enhancement formulators with a biologically active agent that stimulates seedling vigor, drought resistance, and yield in select horticultural and field crops. Formulation chemists apply the raw material in liquid biostimulant concentrates at tightly regulated levels, tracking residual concentration post-blending and before field packaging. Compliance systems for agri-inputs demand transparent traceability and strict limits on application to protect both crops and human health according to global agri-chemical standards.

    Industry compliance standards

    • European Union Regulation (EC) 2019/1009 on plant biostimulants
    • Chinese Ministry of Agriculture NY/T 1977-2010 compliance for biostimulants
    • US EPA 40 CFR 152.6 for plant regulators

    Typical usage ratio

    • 1–10 ppm in foliar sprays or seed treatments; adjusted by crop species and regional approval for integrated pest management (IPM) compatibility

    Downstream process integration

    • High-shear mixing with water and adjuvants in liquid concentrate production
    • Quality sampling pre-bottling to confirm dilution strength
    • Final field container filling with serialized batch ID for traceability

    Final product types

    • Commercial biostimulant liquid products
    • Seed treatment agents and foliar application blends
    Free Quote

    Competitive Hydroxyecdysone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Hydroxyecdysone: Quality and Consistency from Our Production Line

    What Sets Our Hydroxyecdysone Apart in a Competitive Industry

    In the field of plant-derived actives, hydroxyecdysone always draws attention. Years on the production floor have taught us that not all extracts deliver real reliability, especially as customers seek purity for research, dietary supplements, and cosmetics. From a manufacturing standpoint, every batch's journey begins with raw plant material—Ajuga turkestanica or Cyanotis arachnoidea remain the sources we trust after extensive trials and supplier relationships honed by repeated audits and hands-on vetting. Relying on standardized raw input, we target a hydroxyecdysone purity above 98% HPLC, knowing that actual lab confirmation prevents the headaches caused by unwanted plant byproducts or inconsistent color and stability.

    There’s a myth that extraction is a straightforward job. Actual practice demands careful control from plant harvesting, drying, and pulverization right down to pH balancing and cold filtration. Being hands-on with the process reveals subtleties—seasonal differences in plant batches that could change alkaloid profiles, water content, or extraction yield. We address these with real-time adjustments in solvent volumes and stepwise fractionation. It takes the right team: skilled technicians, not just automated systems, to spot the small signals that matter—a shift in absorbance values, a residue color just outside the norm, or an odor change hinting at volatility loss.

    Hydroxyecdysone in Use: Applications Shaped by Real-World Experience

    Our clients arrive with questions about hydroxyecdysone’s benefits in finished formulations, especially where activity and traceability matter. Sports nutrition brands expect clarity on marker compounds for label claims. Cosmetic formulators test batch samples for stability in emulsions. Research teams focus on batch-to-batch repeatability, which is only possible if the upstream manufacturer keeps to strict in-process controls and third-party verified analytics.

    Production experience shows that hydroxyecdysone fits best in formulations when offered as a fine, free-flowing powder. We keep moisture levels below 2% and sieve the powder consistently to a 60–80 mesh granularity—these choices cut caking and make dosing accurate on automated filling lines, saving customers labor and reducing waste. Open discussions with supplement and skincare partners taught us that standardizing this texture and flow behavior gives them fewer excuses for batch errors downstream.

    Often, customers compare hydroxyecdysone with other plant sterols or saponins. Those with roots in chemistry see that, while structures look similar, practical effects and regulations differ. Hydroxyecdysone’s closest functional competitor in supplements may be beta-ecdysone, but subtle differences in hydroxyl group positions show up in how each works in cell culture or in-vivo assays. Over time, we've built a data library by testing these variants head-to-head, helping customers make decisions driven by both molecular testing and real-world feedback from their own applications.

    Process Choices Shaped by Trust and Traceability

    We run a vertically integrated operation. Choosing our own growing partners and keeping extraction, purification, and drying under one roof means accountability lands squarely on our shoulders. By avoiding the patchwork approach that typifies traders or bulk dealers, we trace each batch from seed origin to package labeling. QR codes and in-house tracking systems aren’t decorative—they’re responses to audits and real incidents, like the time a South American lot threw a curveball by showing trace pesticide residues. Solving this called for head-on communication and a hard decision to replace that year’s crop source before any shipments left our site.

    Cleanroom facilities and in-line particle filtration reduce the risk of cross-contamination. No casual equipment swapping. Between hydroxyecdysone and other extracts, our team schedules deep cleaning cycles verified by color trace testing. We documented early on that both visible and HPLC-detectable contaminants sometimes lurk, so vigilance pays off in product stability and reputation. We back every lot with a documented Certificate of Analysis tied to both batch and process controls, not generic library data. This database tracks actual test results for identity (using NMR and HPLC fingerprinting), active content, microbiology, and heavy metals.

    Specifications that Matter: Not Just Purity Numbers

    Hydroxyecdysone’s claimed purity dominates many advertising pitches, but clients with technical backgrounds probe deeper. Our powder meets heavy metal thresholds required for European, US, and Asian food and supplement uses. Lead, cadmium, mercury, and arsenic values rest well below 1 ppm, reflecting not just compliance, but a decade of investment in water purification and exclusion of suspect supply chains. Microbial content checks matter—especially since cosmetic and oral supplement uses require low total aerobic counts, and every test cycle weeds out spore-formers and heat-resistant yeasts.

    We focus on bulk packaging as well. Standard options run in fiber drums lined with double polyethylene bags—for strength and barrier properties—though larger buyers often discuss custom vacuum packing or nitrogen flushing. Each packaging choice reflects input from the folks actually opening containers on plant floors: shelf-life, stack safety, and tear resistance matter as much as cost. Product details printed on every drum include not only lot number and date of manufacture, but also source plant species, making recall or traceability action direct and swift.

    Batch Realities and Customer Feedback

    The real lessons about hydroxyecdysone come from long-term partnerships, not just certificate specs. In one instance, a European sports supplement firm reported a slight off-taste in their protein blend. Collaborative batch review and retention sample testing pointed to a temporary switch in carrier solvent during winter months, which left trace volatiles. Open records and willingness to rework the batch built their trust—and paid off later when a regulatory update called for tighter dioxin controls, which we addressed by reengineering a filtration step and sharing cost transparency.

    Research clients tend to run parallel tests comparing our hydroxyecdysone to competing extracts labeled with similar purities. Results commonly show that genuine high-content material delivers more consistent cell proliferation stimulation or muscle protein synthesis response. Feedback sessions refine our process: a lab reported unexpected high viscosity in solution, prompting us to review and fine-tune drying protocols and milling screens, landing on a powder with improved dispersibility for aqueous applications.

    How Hydroxyecdysone Stands Out from Other Actives

    Most commodity extract dealers talk of “biological activity” in vague terms. We take direct observations and turn them into clear checks: stability under light exposure, water solubility, and response to varied pH and temperature over actual storage periods. Our hydroxyecdysone delivers higher solubility in cold water than saponin-rich extracts, verified by customer blending trials and our own repeated solubility cycling. This matters in ready-to-mix powders and topical formulations where clarity or appearance impacts consumer satisfaction.

    Unlike bulk saponin extracts—which often present as sticky, hygroscopic masses—our hydroxyecdysone resists clumping, stores well under ambient conditions, and holds color, as confirmed by accelerated shelf-life testing. Cosmetic brands praise the consistent, light tan shade of our powder, avoiding reformulation or unexpected tint in finished creams or gels. These small practical benefits aren’t listed in chemical abstracts, but make the difference on busy production lines or in research settings hungry for real reproducibility.

    Sourcing, Testing, and Ongoing Improvements

    Raising the bar for hydroxyecdysone quality requires relentless review of both upstream growing practices and our own downstream verification. Over the past decade, we’ve encouraged growers to switch to integrated pest management and to move away from synthetic growth boosters, after tracing batch impurities back to field use. Yearly onsite visits keep that promise honest, supplementing chemical residue screening that remains part of our intake QC.

    Our in-house lab, equipped with both classic wet chemistry and modern mass spectrometric techniques, keeps us responsive to changing technical requirements. New customer demands—such as higher-resolution impurity profiling for pharmaceutical projects—push us to fine-tune both extraction and purification. For example, we invested in additional ion-exchange steps after feedback revealed certain trace compounds influencing taste and stability. Each upgrade relies on data sharing, not just regulatory shifts, because manufacturers who rely solely on compliance checklists rarely lead on consistent quality.

    Supply disruption, especially in years of unpredictable weather or shipping bottlenecks, remains a challenge. We mitigate this risk by contracting with multiple growers across different regions and maintaining safety stocks. Real experience with disrupted harvests makes clear that keeping a live register of raw material quality, not just third-party certificates, helps avoid last-minute production emergencies.

    Environmental Responsibility in Practice

    Visitors to our factory often ask how production impacts the environment. Being accountable for the entire supply chain presses us to cut waste and energy usage at every step. Solvent recovery loops allow us to reclaim and reuse ethanol and water, cutting down hazardous waste volumes. Post-extraction plant residue, once a disposal issue, now feeds bio-composting projects with local agricultural partners.

    Energy efficiency steps extend to lighting, insulation, and equipment maintenance, cutting overhead and lessening our carbon footprint. We achieve real reduction in per-kilogram production energy use by regular system audits, not slogans on a brochure. These operational changes cost real money up front but return both in regulatory harmony and improved product perception, especially as end users grow more interested in responsible sourcing.

    Long-Term Industry Trends and Forward-Looking Changes

    Markets for hydroxyecdysone continue to evolve, with growing recognition in sports nutrition, anti-aging skincare, and experimental medicine. Regulatory scrutiny is stepping up; more governments require detailed documentation and clearer proof of claims. We've invested early in compliance with evolving regulatory demands—such as ingredient traceability and clearer contaminant limits. Being ahead of regulations, not merely in compliance, means testing for emerging contaminants, verifying plant DNA in sourcing, and documenting every step for both commercial and research customers.

    Customer expectations for transparency shape how we share information. Batch records, test results, and process adjustment logs are open for review, and our technical support teams remain accessible to troubleshoot unique applications. Some clients participate in pilot runs or co-develop protocols for their intended uses, leaning on our tools while sharing their own in-house data back with us. This two-way knowledge exchange has brought about improvements such as batch-specific antioxidant assessments for cosmetic customers and customized micronization for those with novel delivery formats in mind.

    Improving Reliability Through Technology and Team Experience

    Every successful batch of hydroxyecdysone reflects a blend of process automation and human skill. Equipment upgrades make high-volume production realistic, but trained eyes and hands remain essential. Misplaced trust in pure automation once led to unnoticed yield drops until a veteran operator’s daily log picking up a subtle mistake in extraction timing pointed us in the right direction. Staff retention pays dividends, as experienced plant managers anticipate seasonal plant differences and quickly correct course, supported by digital records but grounded in real-world observations.

    Quality isn’t just a slogan for us. Repeated method validation, proficiency tests with outside labs, and continuous improvement feedback bring early warnings of any drift. Regular training and certification for line workers keep knowledge current. This investment builds trust with repeat buyers, who rely on our professionalism to keep their products safe, effective, and regulatory-ready.

    Equipment and methods can always advance. Recent years saw us increase throughput by updating extraction reactor designs and optimizing solvent recycling efficiency. Smaller footprints mean faster cleanouts and lower potential for contamination—a real gain for multi-extract lines. At the same time, we retain flexibility for scale-up projects, allowing custom batches for specialty research and development.

    Hydroxyecdysone in a Crowded Marketplace

    Standing out in the hydroxyecdysone space doesn’t hinge on marketing lingo or generic promises. Reliable suppliers invest years into refining every step of the process, tracking real outcomes rather than just ticking boxes. Customer questions and constant technical challenges push us to keep improving, to document with facts, and to respond when something falls short.

    From sourcing to shipment, every stage brings its own hurdles—unexpected crop failures, supply chain snags, or changes in regulatory outlook. Open lines with customers and continuous dialogue make swift resolution possible, anchoring long-term relationships. Over decades, that approach has proven to be the best foundation for building quality, safety, and practical value into every kilo of hydroxyecdysone we deliver.