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Hippuric Acid Sodium Salt

    • Product Name Hippuric Acid Sodium Salt
    • Alias Benzoylglycine sodium salt
    • Einecs 242-420-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    855201

    Product Name Hippuric Acid Sodium Salt
    Chemical Formula C9H8NNaO3
    Molecular Weight 201.16 g/mol
    Cas Number 2835-99-6
    Appearance White to off-white powder
    Solubility In Water Soluble
    Storage Temperature 2-8°C
    Purity >98%
    Ph Value 6.5-7.5 (1% solution)
    Synonyms N-Benzoylglycine sodium salt
    Ec Number 220-624-1

    As an accredited Hippuric Acid Sodium Salt factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Hippuric Acid Sodium Salt, 100g, is packaged in a sealed, amber glass bottle with a secure screw cap and clear labeling.
    Shipping Hippuric Acid Sodium Salt should be shipped in tightly sealed containers, protected from moisture, light, and incompatible substances. Store at room temperature or as specified by the supplier. Follow all regulatory and safety guidelines for chemical transport, including appropriate labeling and documentation to ensure safe and compliant delivery.
    Storage Hippuric Acid Sodium Salt should be stored in a tightly sealed container, protected from moisture and light. Keep it in a cool, dry, well-ventilated area at room temperature (15–25°C). Avoid exposure to incompatible substances, especially strong acids and oxidizers. Ensure proper labeling and safety precautions are followed to prevent contamination or accidental ingestion. Store away from food and drinking water.
    Application of Hippuric Acid Sodium Salt

    Applications of Hippuric Acid Sodium Salt in Industrial Manufacturing

    As the direct manufacturer, we specifically supply Hippuric Acid Sodium Salt to sectors that structurally rely on its unique biochemical and physicochemical properties. By focusing on well-established downstream applications, we help customers align their processes with current international standards, optimize formula design, and achieve consistently high final product quality.

    1. Pharmaceutical Quality Control Reference Standards

    Pharmaceutical analytical laboratories use Hippuric Acid Sodium Salt as a reference material for calibration and validation of HPLC assays, particularly in amino acid metabolism studies and quality testing for renal diagnostics. Our product supports precise quantification in bioanalytical laboratories to maintain batch consistency and regulatory traceability.

    Industry compliance standards

    • United States Pharmacopeia (USP)
    • European Pharmacopoeia (Ph. Eur.)
    • Good Manufacturing Practice (GMP, ICH Q7)
    • FDA 21 CFR Part 211 (Laboratory Controls)

    Typical usage ratio

    • 0.1–1.0 mg per assay as a calibration standard; lab dosing varies with method sensitivity and instrument validation requirements

    Downstream process integration

    • Operators dissolve the salt in precise buffer solution for analytical standard preparation, then verified by QC chemists at each analytical cycle

    Final product types

    • Analytical reference standards
    • Quality control kits for clinical biochemistry
    • Pharmaceutical validation packages

    2. Diagnostic Test Kit Manufacturing (Kidney Function Biomarkers)

    Producers of in vitro diagnostic kits employ Hippuric Acid Sodium Salt for the standardization and calibration of assays measuring urinary and plasma hippuric acid. It helps clinical device makers achieve traceable, accurate detection of renal clearance and metabolic disorders, ensuring consistent patient diagnostics across batches and markets.

    Industry compliance standards

    • ISO 13485:2016 (Medical Devices—Quality Management)
    • ISO 15189:2022 (Medical Laboratories)
    • CLSI EP17-A2 (Evaluation of Detection Capability)
    • CE-IVD (EU In Vitro Diagnostic Regulation)

    Typical usage ratio

    • 1–10 mg/L in reagent formulation; varies based on desired assay calibration curve and detection threshold

    Downstream process integration

    • Formulation teams dissolve a pre-measured amount into test reagents during bulk kit compounding before lyophilization or liquid filling

    Final product types

    • Clinical kidney function test kits
    • Point-of-care diagnostic cassettes
    • Standardized laboratory controls for metabolic profiling

    3. Research Reagent and Metabolic Pathway Studies in Life Sciences

    Academic and industrial laboratories apply Hippuric Acid Sodium Salt as a primary substrate for enzyme activity assays and as a metabolic intermediate for in vitro studies of xenobiotic conjugation in hepatic systems. Research-grade batches provide traceability and purity required for protocol reproducibility in publications and contract research services.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management)
    • GLP (OECD Principles of Good Laboratory Practice)
    • Material Safety Data Sheet (MSDS) documentation
    • REACH compliance (Europe, where applicable)

    Typical usage ratio

    • 10–150 µM in enzyme kinetics buffer; experimentally adjusted per specific metabolic assay parameters

    Downstream process integration

    • Research staff reconstitute the salt in physiological media, introduce it early in biochemical assay setup, and quantify resultant metabolites by HPLC or LC-MS

    Final product types

    • Metabolic research assay kits
    • Enzyme kinetics study reagents
    • Scientific testing protocols for pharmacokinetics

    4. Food Contact Material Migration Testing

    Independent and manufacturer-owned analytical labs add Hippuric Acid Sodium Salt to food simulants for migration testing of packaging materials, particularly when validating compliance for plasticizers, resins, and coatings that may interact with foodstuffs. The salt acts as a conservative marker to ensure food contact articles meet international migration limits, especially for flavor and metabolite leaching simulations.

    Industry compliance standards

    • EU Regulation No 10/2011 (Plastics Regulation)
    • FDA 21 CFR 177 (Indirect Food Additives)
    • ISO 17025:2017 (Testing and Calibration Laboratories)
    • China GB 4806.1-2016 (General Safety Requirements for Food Contact Materials)

    Typical usage ratio

    • 20–100 mg/L in food simulant solutions; tailored to substrate surface area and extraction conditions specified in protocols

    Downstream process integration

    • Lab analysts incorporate the salt when preparing reference simulant solutions for migration cell tests; measured by chromatography post-migration

    Final product types

    • Standard migration test reports
    • Food contact safety certification dossiers
    • QC control samples for inter-laboratory comparison

    5. Fine Chemical Intermediate Synthesis

    Specialty chemical manufacturers integrate Hippuric Acid Sodium Salt as a protected glycine source or as a selective acyl group donor in the synthesis of custom amide derivatives, including crop protection research compounds and performance materials. Reaction engineers benefit from the salt’s solution stability during controlled addition in batch or continuous production lines.

    Industry compliance standards

    • ISO 9001:2015 (Process Quality Management)
    • Responsible Care® Management System
    • Custom synthesis quality protocols
    • Internal QC based on NMR and purity HPLC

    Typical usage ratio

    • Equivalent to 0.5–5 mol% of desired product in reaction feed, with adjustments based on target conversion and selectivity

    Downstream process integration

    • Technicians charge weighed salt into reaction vessels after initial solvent and catalyst loading; monitored via in-process sampling and titration

    Final product types

    • Custom amide and peptide intermediates
    • Agrochemical research candidates
    • High-purity specialty derivatives for material science
    Free Quote

    Competitive Hippuric Acid Sodium Salt prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    Hippuric Acid Sodium Salt: Precision from an Experienced Manufacturer

    Our Hands-on Approach to Hippuric Acid Sodium Salt

    Anyone who’s spent time on a production floor knows that not all raw materials are alike. The same name on a drum tells only part of the story. Producing Hippuric Acid Sodium Salt requires more than careful batch chemistry—it demands vigilance at every step, from sourcing benzoic acid of stellar purity to verifying crystallization consistency, to making sure each lot meets the real needs of laboratories or industrial facilities counting on reliable results. Deliveries leave our plant only after we’ve done every test we’d expect a customer’s QC lab to run for themselves.

    What Sets Our Hippuric Acid Sodium Salt Apart

    We produce Hippuric Acid Sodium Salt with attention to repeatability, batch after batch. Chemical identity matters, but it’s the small details—moisture control, particle sizing, freedom from unreacted byproducts—that keep users confident. Years spent troubleshooting formulations have taught us that residue from other sodium salts, or marginal solvents, leads to erratic reactions, messy separations, or detector-skewing baseline noise in chromatography. By controlling the final recrystallization, we've reduced these issues. Our operations keep metals and process contaminants well below thresholds mandated in analytical work.

    Some users watch sodium ion content; others monitor chloride background. We’ve narrowed both. Some need assurance on solubility at pH extremes or in mixed aqueous/organic buffers. Our QA team finds out the limits, pushing solubility and stability in the actual stock solutions our customers use. This practical knowledge often matters more than the numbers found on a commodity spec sheet.

    Our Product Model, Grades, and Microstructure

    We supply Hippuric Acid Sodium Salt under our proprietary model designation developed for traceability. Model identifiers reflect batch genealogy, deviations in process, reagent source, and year. Structures have evolved; we shifted drying protocols away from high-heat approaches that risked forming unwanted sodium benzoate, and invested in filtration hardware to prevent fiber and dust.

    Particle size isn’t just an afterthought for us. In quantitative analysis, too coarse a powder risks poor dissolution, while extra-fine grades clump or float on mixing. Guided by actual feedback from our long-term pharmaceutical clients, we settle granulation within a narrow range for easy dispersion instead of simply meeting a mesh-size minimum. As a manufacturer, we saw firsthand how this difference reduces headaches during daily weighing and solution prep.

    Purity, Trace Impurities, and Analytical Control

    Years of refining our processes means we now hit purity levels beyond 99%. In many labs, trace impurities spark unwanted signals or interfere in biological assays. Our experience troubleshooting samples taught us to avoid cross-reactions: raw materials show zero detectable benzyl derivatives, phthalates, or process stabilizers that commonly plague commodity materials grinded out for bulk. Manufacturing with closed-loop solvent recovery reduces unknowns, so lot-to-lot variance stays low.

    Some clients require hippuric acid sodium salt for use as standard material in chromatographic calibration. For them, we include additional analytical runs: HPLC purity, full water content logged by Karl Fischer titration, and detailed reporting on UV-absorption characteristics. All these checks help our clients avoid failed runs and last-minute source re-qualification.

    Uses and Applications: Lessons from Real-World Practice

    Not every batch of Hippuric Acid Sodium Salt finds the same use once it leaves our facility. Some shipments head to biochemical research labs tracing aromatic compound metabolism. Others support industrial hygiene tests for toluene exposure, where hippuric acid shows up as a metabolic marker in urine samples. One of our oldest clients, a veterinary pharmaceutical producer, relies on it for intermediate synthesis of diagnostic reagents. Each application brings its own technical complications.

    Through frequent technical back-and-forth with users, we’ve learned to anticipate the stumbling blocks. Fast solubility in pH-shifted buffer solutions keeps workflow moving in medical analysis. Pharmaceutical-grade stability ensures bioassay controls stay valid until the last vial has been checked. Some customers in analytical toxicology need very low background levels for sensitive mass spectrometry; our low metal and chloride signature arises from validated equipment cleaning and filtered water inputs.

    We’ve also fielded requests for custom packaging, whether for gram-scale precise laboratory use or larger, bulk containers for process-scale needs. Packaging has evolved: moisture-barrier liners and tamper-evident seals matter when a fraction of a percent water uptake can throw off a critical calibration.

    Comparison with Other Sodium Salts and Hippuric Acid Forms

    Many customers ask how Hippuric Acid Sodium Salt stands apart from its cousins—such as hippuric acid’s pure acid form, other sodium carboxylates, or simpler benzoic derivatives. The sodium salt’s unique properties make handling easier. Unlike pure hippuric acid, the sodium salt form dissolves swiftly in neutral buffers and stays in solution over a broader pH range. That is crucial for metabolic research, allowing clean and reproducible sample preparation. We found that acid forms often require longer dissolution times and repeated mixing, wasting both solvent and technician labor in high-throughput labs.

    Compared to more common sodium carboxylates, like sodium benzoate or sodium acetate, hippuric acid sodium salt contains the additional glycine moiety, which can interfere less with certain enzyme or receptor assays. Differences in zwitterionic character affect the salt’s behavior in chromatographic separations and can help avoid co-elution with background substances, a point that came up more than once during pilot projects with pesticide residue screens.

    We never treat our sodium salt as an interchangeable substitute for every sodium carboxylate or hippuric acid. Cross-contamination even at low levels changes stability profiles, alters endpoint detection wavelength, or pushes a system out of calibration. It’s these lessons—drawn from real customers running real assays, and not from standard catalogs—that drive our ongoing in-house process review.

    Quality Assurance: History and Philosophy

    There’s no shortcut to building a reputation as a reliable source in the laboratory reagents market. Over the years, we’ve moved beyond spot-check analysis. Daily instrument calibration is standard for us—spectrometers, moisture analyzers, and balancers see regular third-party inspection. Documentation matters. When we started, we tracked batches on paper forms; now, all batch histories, test records, and operator logs live in a secure digital archive accessible for audits.

    Mistakes happen in every plant. In the early days, a single incomplete wash cycle produced a run with slight yellow tint—a sign of residual benzoic acid or other chromophores. From that lesson came stricter cleaning validation and colorimetric endpoints for every finished lot. No shipment leaves for a client’s lab before clearing these checks. Sustainability isn’t a buzzword here: every process update, from solvent reclamation to utility metering, has proven itself in lowered waste or consistent product.

    Regulatory Compliance and Transparency

    Navigating the complex requirements of various regulatory bodies has shaped our documentation standards. Throughout the manufacturing process, we follow strict audit trails—ensuring traceability back to the source of every ingredient, and verifying cleaning procedures on all equipment, as required under modern good manufacturing standards. Transparency means we openly communicate about any nonconformity or process deviation. If conditions change that affect downstream application, customers hear from us first.

    Many applications—especially in environmental or clinical settings—call for rigorous quality documentation. We maintain comprehensive batch records and support all shipments with certificates of analysis that reflect our real in-process controls, not just boilerplate numbers. Stocking our own analytical reference materials, we can confirm traceability to international standards for those customers who require it.

    Working with Clients: Challenges and Collaborations

    Clients sometimes underestimate the impact a small change in ingredient profile can have on their own workflows. We recall a project with a European clinical lab, where trace methanol in a shipment threw off their GC-MS readings. Solving the problem meant more than cleaning up our process. We established a channel for rapid feedback, and started offering pre-ship sample runs for all sensitive end-users. By treating customer feedback as valuable process input, our batches have gotten incrementally better.

    Over years of partnership with pharmaceutical and biochemical research groups, we’ve tailored small but real improvements that only firsthand use highlights. Our product development team visits client sites to see how our products are used in daily lab and plant protocols. These site visits help our R&D stay grounded in the daily realities, prompting tweaks in pH adjustment or filtration that bulk suppliers rarely notice.

    Supporting Researchers and Process Engineers

    Applied science doesn’t always play out as planned on a whiteboard. Early-stage researchers and commercial process engineers alike benefit from our willingness to talk through exactly what each batch will do in the lab or plant—not just what it was designed for. Solutions sometimes involve simple changes, like recalibrating pH in our final product to match process needs, or packaging in low-static bottles for micro-weight accuracy.

    Technical challenges arise. Clients call us for advice on scale-up from grams to kilograms. Questions range from buffer compatibility to solubility limits in unique solvents. Because we do our own application-focused validation, we’re ready to advise with real numbers, test results, and case studies reflecting actual materials shipped—not theoretical expectations borrowed from suppliers upstream.

    Environmental Responsibility and Sustainability in Chemical Manufacturing

    Years of operation have shown how critical environmental stewardship is both for community trust and long-term business stability. Early on, inefficient solvent handling resulted in unnecessary waste and off-gassing from open batch reactors. Gradually upgrading to closed-cycle solvent recovery, optimizing water use, and minimizing byproduct streams now yields cleaner output, less operational downtime, and less risk.

    Sourcing plays its part. We prioritize input materials from producers who share our environmental values and whose processes align with internationally recognized environmental standards. Each step, from improving storage and transfer procedures to enhancing waste capture and recycling technology, means fewer disruptions for us and for our customers, whose own sustainability projects often depend on reliable, certifiable sources.

    The Value of Direct Manufacturer Relationships

    As a direct manufacturer, we can respond flexibly to requests that large distribution chains aren’t built to handle. Custom specification? Adjustment in assay documentation? Deviation in secondary ions or background compounds? All of these are real conversations we’ve had, and real solutions we’ve developed for individual partners. By maintaining control over every aspect of production and testing, we guarantee more than a label—we build confidence batch by batch.

    Clients who work with us don’t have to worry about upstream unknowns or mixed-batch bottling by brokers. Our logs reflect what happens in our own facility, traceable from raw input to finished container. That direct link shortens response time, enables root-cause analysis for any concern, and makes it straightforward to implement requested process changes or accommodate one-off research requests.

    Continuous Improvement Driven by User Experience

    Chemistry is always moving forward, and so does our process. Feedback from the field—whether it’s a solubility oddity, baseline drift in forensics, or unexpected absorption in bioassays—pushes us to revisit and refine both production and QA protocols. Everything we change, we validate first, and we invite our partners to evaluate those changes directly.

    Our technical and quality staff meet regularly, reviewing both internal and customer feedback, running tests, and keeping detailed change control records. Every season brings something new—a process tweak, equipment update, or analytical method upgrade fueled by real-world user input. Maintaining this kind of transparency and continuous learning isn’t a marketing stance; it’s how we keep earning our clients’ trust.

    Reflections as an Experienced Producer

    Decades in chemical manufacturing teach lessons that can’t be found in textbooks or data sheets. Consistency means more than meeting a standard once—it means responding to every variable, every subtle shift in input or process, in a way that minimizes impact for the end user. Customers have come to rely on our Hippuric Acid Sodium Salt not just because of the stated purity, but because behind each drum stands a culture of responsibility, hands-on troubleshooting, and careful follow-through at every stage.

    As end uses for this compound develop, we stay ready to adapt. Whether supporting cutting-edge research, scaling up for industrial diagnostics, or ensuring long-term product shelf life, our commitment remains to deliver chemicals that fit the real-world work our clients do every day. This kind of partnership and responsiveness, built on decades of direct production experience, keeps our Hippuric Acid Sodium Salt a trusted resource for both established and emerging needs.