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Hexadecanedioic Acid

    • Product Name Hexadecanedioic Acid
    • Alias C16 diacid
    • Einecs 204-664-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    921456

    Chemical Name Hexadecanedioic Acid
    Molecular Formula C16H30O4
    Molar Mass 286.41 g/mol
    Cas Number 505-57-7
    Appearance White crystalline powder
    Melting Point 133-135°C
    Boiling Point N/A (decomposes)
    Solubility In Water Slightly soluble
    Density 1.19 g/cm³
    Odor Odorless
    Pka 4.89
    Synonyms Thapsic acid
    Structural Formula HOOC-(CH2)14-COOH
    Refractive Index N/A
    Logp 4.52

    As an accredited Hexadecanedioic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Hexadecanedioic Acid is supplied in a 500g amber glass bottle, labeled with safety information and storage instructions for laboratory use.
    Shipping Hexadecanedioic Acid is typically shipped in tightly sealed containers, protected from moisture and incompatible materials. It should be transported at ambient temperatures, following applicable regulations for non-hazardous chemicals. Proper labeling and documentation are required to ensure safe handling and compliance with all transportation guidelines. Avoid sources of ignition during transit.
    Storage Hexadecanedioic acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Keep it away from direct sunlight, heat, and sources of ignition. Store at room temperature and avoid excessive moisture. Proper labeling and secure location are essential to prevent accidental exposure or contamination.
    Application of Hexadecanedioic Acid

    Applications of Hexadecanedioic Acid in Industrial Manufacturing

    Hexadecanedioic Acid, known for its 16-carbon saturated dicarboxylic structure, plays a critical role in several targeted industrial applications. Our expertise as the direct manufacturer ensures strict batch-to-batch consistency, supporting precision use in polymer synthesis, specialty lubricants, high-performance coatings, pharmaceutical intermediates, and plasticizer formulations. Below, we detail typical downstream scenarios substantiated by industrial standards and real manufacturing workflows.

    1. Synthesis of High-Performance Polyamides

    Polyamide producers frequently incorporate this diacid as a key monomer to achieve enhanced thermal stability and flexibility in specialty nylon compounds. Industrial synthesis routes utilize it for manufacturing long-chain polyamides with improved melt processing characteristics, serving demanding sectors such as automotive and electronics where long-chain aliphatic nylons outperform shorter variants.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • IEC 61249-2-21 for halogen-free, high-temperature electronic laminates
    • Automotive OEM specifications (e.g., VW TL 52232)
    • REACH Annex XVII compliance

    Typical usage ratio

    • 25%–50% by mole in dicarboxylic component for copolymerization; dose adjusted based on chain length requirements and target glass transition temperature

    Downstream process integration

    • Charged directly as one of two main polycondensation monomers, melted and reacted with diamines (e.g., hexamethylenediamine) under nitrogen at elevated temperatures in autoclaves

    Final product types

    • Long-chain PA16 nylon resins
    • Co-polyamide granules for injection molding
    • Flexible circuit board base films
    • High-flexion automotive connectors

    2. Formulation of Synthetic Ester-Based Lubricants

    Performance lubricant blenders add this dicarboxylic acid to formulate synthetic diesters that deliver low volatility and superior hydrolytic stability in industrial and automotive lubricant base stocks. Its structure imparts extended drain intervals and improved viscosity indices in high-load or oxidation-prone environments, such as compressors or hydraulic systems.

    Industry compliance standards

    • DIN 51517-3 (lubricating oils - testing for industrial gear oils)
    • ASTM D445 (viscosity measurements)
    • API SN/CF (Engine Oil Performance Standards)
    • ISO 15380 (biodegradable lubricants for hydraulic fluids)

    Typical usage ratio

    • 35%–60% by total acid content for diester synthesis; varies with viscosity grade and desired pour point characteristics

    Downstream process integration

    • Esterified with C8–C10 alcohols in batch or continuous reactors using acid catalysis; neutralization and distillation yield pure diester base oils

    Final product types

    • Diester synthetic compressor lubricants
    • Biodegradable hydraulic fluids
    • Industrial gear oils for wind turbines
    • Automotive transmission fluids

    3. Curing Agent for High-Durability Powder Coatings

    Manufacturers of powder coatings specifically value the diacid for improving flexibility and weather resistance of polyester crosslinked coatings. The extended methylene sequence in its molecule aids in balancing hardness and impact resistance on coated metal parts, supporting architectural or outdoor applications exposed to thermal cycling and UV radiation.

    Industry compliance standards

    • Qualicoat (International Quality Label for architectural powder coatings)
    • ISO 8130 (methods for testing powder coatings)
    • RoHS Directive (2011/65/EU) for hazardous substances
    • GB/T 5237.4 (China’s aluminum profile coating standard)

    Typical usage ratio

    • 10%–25% of total polyol-acid blend for polyester backbones; modulated according to gloss, flexibility, and curing performance requirements

    Downstream process integration

    • Polycondensed with glycols to form prepolymers, extruded with curing agents and additives; final application by electrostatic spraying and oven curing on metal substrates

    Final product types

    • Architectural exterior powder coatings
    • Outdoor furniture finishes
    • High-durability pipeline coatings
    • Appliance protective films

    4. Intermediate for Statin Pharmaceutical Synthesis

    In the pharmaceutical industry, hexadecanedioic acid serves as a selective precursor in multi-step synthesis for certain statin-class APIs. Its symmetrical dicarboxylic structure provides efficient chain extension or functionalization at late stages of statin molecule construction, where strict impurity profiles and traceability demand high-purity inputs and validated supply chain protocols.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • Current USP/NF monographs (United States Pharmacopeia/National Formulary)
    • EU GMP Part II for API manufacturing
    • Ph. Eur. monographs relevant to statin intermediates

    Typical usage ratio

    • Stoichiometric, as defined by the target synthesis route (e.g., full equivalent required per desired statin molecule step); process control maintains ±2% input to ensure yield and quality

    Downstream process integration

    • Introduced during side-chain elongation or dicarboxyl functional group installation, typically in condensation or amidation reactions under controlled temperature and pH conditions in GMP reactors

    Final product types

    • Lovastatin and related statin active pharmaceutical ingredients (APIs)
    • Intermediates for simvastatin, pravastatin, or atorvastatin synthesis
    • Statin precursor fine chemicals
    • High-purity specialty pharma intermediates

    5. Plasticizer Precursor for Flexible Polyvinyl Chloride

    Producers of flexible PVC utilize this diacid as a feedstock for high-molecular-weight linear diester plasticizer synthesis. These plasticizers boost migration resistance and maintain long-term flexibility in wire insulation, flooring, automotive sheeting, and medical-grade soft PVC, addressing concerns about phthalate alternatives in sensitive applications.

    Industry compliance standards

    • EN 71-3 (safety for toys regarding migration of certain elements)
    • FDA 21 CFR 177.2600 (elastomers for food contact)
    • REACH SVHC (Substances of Very High Concern) for non-phthalate plasticizers
    • ISO 10993 (biocompatibility for medical-grade materials)

    Typical usage ratio

    • 15%–35% of total plasticizer-blend mass; selected for target softness, migration, and anti-fog properties in the final formulation

    Downstream process integration

    • Esterified with C8–C10 alcohols under acid catalysis, followed by blending with PVC resin during compounding or calendaring; precise dosing controlled by dynamic plastograph testing

    Final product types

    • Phthalate-free medical tubing and blood bags
    • PVC flooring and wall coverings
    • Soft automotive interiors
    • Electrical wire and cable insulation
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    Certification & Compliance
    More Introduction

    Hexadecanedioic Acid: Real-World Perspective from a Chemical Manufacturer

    Stepping into the Realities of Hexadecanedioic Acid Production

    Over the years, producing specialty chemicals has required more than technical documents and marketing jargon. It takes daily troubleshooting, real product knowledge, and a straightforward approach to each batch and shipment. Hexadecanedioic Acid, also known as C16 Dicarboxylic Acid, has become a foundation block in our product line. We don’t assemble it as if it’s just another item on a catalog. This acid takes careful attention at every step: raw material choices, reaction controls, purification setups, even the packaging run for each customer’s needs.

    Model and Specifications: Manufacturing Practicality Over Theory

    Our Hexadecanedioic Acid, with the model designation matching the IUPAC name, is produced as a white crystalline powder. Most of our batches come with a purity specification above 99%. We’ve done this through iterative process control, using feedstocks with reliably consistent chain lengths and experienced operators monitoring crystallization phases. The melting point anchors around 132°C to 136°C, without drifting. We maintain moisture and ash content low—measured and recorded daily, not because of a regulatory checkbox, but to ensure our customers don’t run into processing headaches later. Impurities and lower homologs get screened out at the isolation stage, and we keep an eagle eye for even minor color shifts, since even faint discoloration can hint at unwanted by-products.

    From a bulk handling viewpoint, we offer packaging that holds up in transit, whether customers want fiber drums or lined kraft bags. We learned early that moisture ingress ruins entire lots, so we seal up each batch tightly before it leaves the final inspection line. Most requests come in for 25 kilogram units, but we’ve packed everything from smaller drums for specialty users to multi-ton super sacks or ISO containers for large-scale runs.

    Understanding Industry Demand for Hexadecanedioic Acid

    Market interest has picked up alongside the wider push for nylon and polyester innovation. Our clients range from synthetic lubricant producers to R&D teams working on thermoplastic elastomers. Hexadecanedioic Acid takes a special role because, as a C16 diacid, it sits at the longer chain end of dicarboxylic acids used to build specialty polyamides. For PA-6,16 and PA-4,16, the acid introduces a flexibility absent from shorter analogs like sebacic acid. It’s not just book knowledge. Feedback from polymer plants highlights its purpose: when they aim for higher performance, greater elongation at break, or better hydrolytic stability, the extra methylene units in C16 dicarboxylic acid pay off in the final product’s feel and durability.

    On the lubricant additives side, our customers talk less about polymer structures and more about end results. Hexadecanedioic Acid acts as a strong corrosion inhibitor and provides oxidative stability to greases and specialty lubricants. It extends machinery lifetime and minimizes maintenance calls. Chemical plants often want cleaner-running machinery, so they search for acid components that won’t break down, even under extreme temperature swings or long-term load. Our product’s longer chain structure, compared to azelaic or adipic acid, fits these niche requirements.

    We’ve supplied active pharmaceutical ingredient manufacturers, as certain drug synthesis schemes demand long-chain dicarboxylic building blocks with exacting requirements for purity, inertness, and low metal content. If the process needs tough oxidative stability during drug crystallization, Hexadecanedioic Acid avoids introducing side products that could compromise a batch. These industries may only need kilograms at a time, but their standards for trace metal impurities and color quality keep us on our toes.

    How Hexadecanedioic Acid Compares with Other Dicarboxylic Acids

    Over years of direct manufacturing experience, we’ve seen first-hand where C16 dicarboxylic acid diverges from shorter or branched alternatives. Adipic acid and sebacic acid remain go-tos for standard nylon production, yet when end-users ask for materials with higher resistance to heat and solvents, Hexadecanedioic Acid stands out. Its extended hydrocarbon chain delivers flexibility to polyamides while maintaining crystallinity—a unique blend that couldn’t be achieved with lower homologs.

    Another distinction appears in industrial lubricants. Shorter-chain acids might dissolve or break down when exposed to sustained high-temperature cycles. Our product’s thermal stability lets it stand up to tests that shorter diacids can’t pass, whether in automotive lubricants or specialty grease for aviation and heavy machinery. Real stories come in from customers who tried to save on costs with less expensive acids, only to face product failures under stress. Those hard lessons reinforce the need for the C16 backbone our process supplies.

    From a handling perspective, Hexadecanedioic Acid resists caking and lumping more than acids like dodecanedioic or suberic acid. We’ve fine-tuned our drying process to maintain flowability, especially essential for customers running automated dispensing or blending systems. In tropical climates or damp storage environments, this moisture resistance can make or break a production schedule; that’s feedback we hear directly from operations staff rather than the purchasing department.

    Applications in Polymer Manufacturing: More Than Just a Feedstock

    Chemical manufacturing isn’t about pushing a product out the door; it's about understanding why polymer plants request Hexadecanedioic Acid and anticipating what quality means in their context. Nylon producers rely on its long-chain structure for adjusting melting points and crystallinity in their high-tenacity fibers and engineering resins. We’ve worked alongside these teams, troubleshooting issues ranging from solvent compatibility to reaction yield. Success hinges on tight control of acid value, color, and residual solvent—areas where shortcuts lead straight to blocked extruders or off-grade resin.

    In the composites sector, research teams often approach us for consultations on compatibility with non-traditional co-monomers. Blending C16 diacid with specialized diamines sometimes pushes crystallization behaviors outside textbook trends. We gather batch samples, run them in our in-house pilot extruder, and review the mechanical properties with their team—not because it’s contractually required but because those iterations build trust and repeated orders. Our willingness to run smaller pilot batches and adjust product grain size or thermal profile distinguishes our approach from those who treat chemical manufacturing as bulk throughput.

    Performance in Lubricant and Grease Formulation

    Lubricant blenders and grease formulators knock on our door when they need ingredients that will handle real-world conditions—heat, metal wear, shear over months, or even years. Hexadecanedioic Acid goes into producing calcium and lithium soaps favored for their high-dropping points and water resistance. The C16 chain resists saponification-defects, keeping water insolubility high and oil bleed low. On the marine and automotive side, those differences are worth more than any line item savings, as every equipment breakdown means lost hours and rising costs.

    We’ve worked on site with additive formulators as they chased a specific target level for copper corrosion or wear-scarring in bench tests. Our involvement didn’t end at shipment—our technical staff joined the QA team in reviewing post-blending stability studies. When a customer faced inconsistent batch behavior using commodity chain acids, we adjusted our process to deliver even lower residual aldehyde levels, helping them restore confidence with their OEM customers. It’s these nuances, shaped by feedback and real field data, that keep Hexadecanedioic Acid a staple in formulators’ lineups.

    Meeting the Quality Challenge: Traceability and Process Control

    Supplying specialty chemicals is about consistency, not just purity numbers on a data sheet. We keep samples from every lot and maintain detailed batch records. Customers often call in with technical questions and expect more than a transactional answer. If an unexpected test result arises, we trace back every stage—from raw material receipt to reactor temperature logs and even storage warehouse humidity data. This level of traceability isn’t just a best practice. It’s a response to real supply chain pressures our customers face when serving regulated industries.

    Every reactor cycle produces unique challenges: catalyst inhibition, impurity spikes, filtration hold-ups. We never hold back from discussing production setbacks with long-term partners. Whether it’s tweaking conditioning beds for finer crystallization or revisiting drying curves to prevent clumping in humid months, we treat those solutions as shared investments in long-term trust.

    Responding to Regulatory and Sustainability Trends

    End users and brand owners increasingly measure sustainability records, regulatory compliance, and even carbon footprint on all chemical inputs. We’ve adapted, not because of outside pressure, but from understanding where downstream industries are heading. Our process engineers worked with external laboratories to validate that every batch falls below European REACH thresholds for hazardous impurities. We pay strict attention to residual heavy metals, phthalate content, and persistent organic pollutants.

    On carbon impact, we’ve backed up improvements with real numbers. We installed heat-exchange systems to capture process heat and reduce gas consumption. These steps cut directly into running energy usage and let us price our Hexadecanedioic Acid competitively without skimping on quality. Internally, we task production managers with continuous cycle time monitoring, and we don’t shy away from reporting variances to customers who need full life-cycle data for their own audits.

    How We Handle Changing Market Needs

    The market for long-chain dicarboxylic acids isn’t static. We see clear cycles where textile, automotive, or electronics companies shift their requirements. During periods of high PA-6,16 demand, our tanks run at capacity. When bioplastics and green polymers attract attention, our R&D group pivots to custom blends, developing hybrid grades or even bio-based raw material sources. In scenarios where customers face unpredictable shifts in their own supply chains, they ask for tighter supply windows or smaller batch sizes; we run the plant with these real-world pressures in mind.

    Sometimes, it’s about the unexpected: transport bottlenecks, port strikes, or energy price surges. Flexibility in production scheduling has become one of our most valued attributes. We keep reserve capacity for priority customers and stay in touch daily with logistics partners. When a key user reported an unplanned spike in need for additional Hexadecanedioic Acid, our response wasn’t a stock answer but a shift in our daily blend schedule to get them covered.

    Addressing Common Issues with the Product’s Use

    Even the best-made Hexadecanedioic Acid causes issues if not handled properly. We hear stories of clumping, flow reduction, or delayed dissolution. Each report pushes us to refine our drying and stabilization stages. We also provide practical advice: store packaging sealed, out of direct sunlight, above freezing—details grounded in our own warehouse mistakes from earlier years. Not every distributor or competitor will admit to those chapters, but we adapt based on what actually works, not what’s supposed to work in theory.

    Whenever a customer’s blending line jams or a batch analysis reveals out-of-spec values, we open our own product notebooks. A recent example saw a customer’s processing window narrow due to ambient moisture pulling into open drums. We examined their site storage, suggested desiccant-packed containment, and ran mock-up tests in our own shipping shed to show how product handling affects final use. Real-world solutions win repeat business—it’s that simple.

    Forward Thinking: Hexadecanedioic Acid in Emerging Technologies

    The next wave of industry innovation draws heavily on specialty building blocks like Hexadecanedioic Acid. As electric vehicle demand rises, new generations of polyamide insulation require chain extenders that won’t degrade under high voltage stress or extreme cycling. Our engagement isn’t just as a supplier but as a technical counterpart, reviewing stability results or proposing tweaks to grade particle size for fine powder electrospinning lines.

    On the sustainability front, the search for next-generation biopolymers puts unique pressure on acid suppliers. While some companies focus only on feedstock certification, we track actual resin performance, collaborating in cross-industry working groups to ensure new compostable materials don’t sacrifice shelf life or processability. These demands keep our site engineers in continual dialogue with lab researchers and pilot-plant development teams for customers around the world.

    Why Manufacturing Perspective Matters

    Many chemical suppliers rely on third-party sourcing and re-labeling, recycling the same technical bullet points. We’ve taken a different path by actually running the reactors, logging quality on the shop floor, and opening our records to partners who care about long-term supply. It’s an approach built on transparency: we don’t withhold when an issue crops up, nor do we promise what a process can’t deliver within realistic tolerances.

    Our team fields calls from production, maintenance, and even R&D staff at customer sites, not only purchasing agents. Whether they request updated specs, want input on a processing trial, or look for emergency deliveries after a shipper’s truck broke down, they know they’re not talking to a middleman but to real people with direct accountability for every drum and every shipment. This willingness to stay close to the product, rather than treating Hexadecanedioic Acid as just another commodity, defines the way we do business every day.

    Direct Industry Experience Pays Off

    Each feedback loop—blending, R&D, troubleshooting—feeds back into how we run production, conduct lab analysis, and schedule plant downtime. Our commitment begins at feedstock selection and ends only after product runs smoothly in the customer's process. By actively sharing both wins and problems, we’ve built relationships that have weathered years of technological change, market swings, and even global supply chain disruptions.

    Hexadecanedioic Acid may look similar to other dicarboxylic acids on paper, but running a chemical plant soon reveals every unique behavior—thermal, chemical, or handling. The differences show up in longer part lifespans, reduced lubricant breakdown, and more reliable composite parts, proving that detail and reliability matter from sourcing to final shipment. We welcome customers to tap into our hands-on perspective, so their own operations stay competitive, consistent, and a step ahead of whatever changes tomorrow may bring.