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Glyoxime

    • Product Name Glyoxime
    • Alias Dioximedione
    • Einecs 209-203-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    179558

    Chemicalname Glyoxime
    Molecularformula C2H4N2O2
    Molarmass 88.07 g/mol
    Appearance White to slightly yellow crystalline powder
    Meltingpoint 240-250 °C (decomposes)
    Solubilityinwater Slightly soluble
    Density 1.43 g/cm³
    Casnumber 140-51-4
    Boilingpoint Decomposes before boiling
    Iupacname N,N'-dihydroxyethanediamidine
    Pubchemcid 6881
    Ph Neutral to slightly basic in solution

    As an accredited Glyoxime factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Glyoxime is packaged in a sealed, amber glass bottle containing 25 grams, featuring hazard labeling and secure, chemical-resistant cap.
    Shipping Glyoxime should be shipped in tightly sealed containers, protected from moisture and incompatible substances. It must be labeled according to regulatory standards, transported in compliance with local and international hazardous material guidelines, and kept away from heat and ignition sources. Ensure secure packaging to prevent leaks or spills during transit.
    Storage Glyoxime should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of ignition. Keep it away from incompatible substances such as strong oxidizing agents. Protect the chemical from moisture and direct sunlight. Clearly label the storage container and ensure access is limited to trained personnel. Store following appropriate chemical safety guidelines.
    Application of Glyoxime

    Applications of Glyoxime in Industrial Manufacturing

    Glyoxime serves as a specialized chemical intermediate across multiple industrial sectors. Our production expertise ensures reliable supply, consistent quality, and full regulatory conformity for demanding downstream applications.

    1. Nickel Detection and Quantification in Analytical Chemistry

    Many industrial laboratories incorporate glyoxime as a key chelating reagent for colorimetric nickel analysis. Analysts combine glyoxime in ammoniacal solutions with sample matrices to form solid nickel dimethylglyoxime complexes. The intense red precipitate gives rapid, quantitative determination critical in mining, electroplating, and environmental compliance labs. Only reagent-grade glyoxime achieves reliable detection limits and accuracy required for regulatory monitoring and industrial QC procedures.

    Industry compliance standards

    • ISO 6353-1:1982 for laboratory use
    • EPA SW-846 Method 3500-Ni Determination
    • DIN 38406-13 for water and wastewater analysis
    • REACH chemical registration for reagent supply

    Typical usage ratio

    • 0.5–2.0 mg glyoxime per 1 mg Ni analyzed; dosage adjusts to matrix interference and calibration curve span

    Downstream process integration

    • Dissolve in ethanol or ammonia prior to sample addition
    • Introduce to digested or extracted sample solutions
    • Mix under alkaline conditions to promote selective nickel chelation
    • Filter and weigh colored complex for quantification

    Final product types

    • Nickel spectrometric assay kits
    • Pre-formulated analytical standards
    • Nickel test strip formulations
    • Custom laboratory test reagents

    2. Catalysts and Ligand Synthesis for Fine Chemicals

    Glyoxime molecules, due to their bidentate nature, provide essential ligand functionality in the synthesis of transition metal complexes. Manufacturers in the chemicals and pharma sector utilize these ligands to produce nickel(II) and cobalt(II) glyoxime complexes, vital for catalytic hydrogenation, hydrocyanation, and specialty synthetic transformations. Process control hinges on trace purity and controlled addition to guarantee stable, homogeneous catalysts and prevent unwanted by-products.

    Industry compliance standards

    • ISO 9001 quality management for catalyst materials
    • REACH Annex VII registration for chemical intermediates
    • Responsible Care solvent handling protocols

    Typical usage ratio

    • Generally 1:1.1 molar ratio with nickel or cobalt salts in catalyst ligand synthesis; ratio may vary up to 5% based on desired complex architecture

    Downstream process integration

    • Dissolution in compatible organic solvent systems such as ethanol or methanol
    • Co-precipitation or slow addition to transition metal ion solutions under pH-controlled conditions
    • Direct transfer to catalyst reactors or blending tanks
    • Isolation and drying of the metal glyoxime catalyst complex

    Final product types

    • Nickel(II) glyoxime catalysts
    • Cobalt(II) glyoxime complexes
    • Custom bidentate ligand packages for OEM catalyst suppliers
    • Specialty chemical reagents for pharmaceutical synthesis

    3. Metal Finishing and Plating Wastewater Treatment

    Effluent streams from metal plating and surface finishing facilities frequently require removal of dissolved nickel ions before discharge. Plant operators dose glyoxime into neutralized, filtered process water tanks to precipitate nickel as an insoluble complex. Due to its high selectivity and minimal interference by other metals, glyoxime enables plants to achieve permitted heavy metal limits without overuse of general chelating agents and reduces overall sludge volumes.

    Industry compliance standards

    • EU Water Framework Directive 2000/60/EC
    • Local effluent discharge limits (e.g., US EPA 40 CFR Part 433)
    • ISO 14001:2015 for environmental management

    Typical usage ratio

    • Stoichiometric addition: 1.05–1.15 mol glyoxime per 1 mol Ni detected in wastewater; ratio optimized per onsite pilot jar tests

    Downstream process integration

    • Continuous or batch dosing after equalization and neutralization towers
    • Rapid mixing to maximize precipitation and settling
    • Sludge dewatering and safe disposal according to hazardous waste guidelines

    Final product types

    • N/A (treated and compliant discharge water)
    • Nickel-rich filter cake for hazardous waste management

    4. Organic Synthesis Intermediate in Agrochemical Production

    Formulation chemists select glyoxime as a precise precursor for producing certain pesticide and herbicide active ingredients. Its controlled reactivity enables selective oxime and imine transformations in multi-step syntheses. High consistency in melting point and minimal trace metal content remain vital to minimize batch variability for crop protection actives where glyoxime conversion yield impacts final potency and recovery rates.

    Industry compliance standards

    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • ISO 17025 accredited process control
    • EU Regulation (EC) No 1107/2009 authorizations for plant protection products

    Typical usage ratio

    • 5–15% by weight in multi-step pesticide intermediate runs; recipe design adapts based on the target molecule structure and yield optimization

    Downstream process integration

    • Charge into reaction vessels during heterocyclic core assembly
    • Stepwise addition to control intermediate formation rates
    • Integration into synthetic flowsheets with inline process analytics

    Final product types

    • Technical grade pesticide active intermediates
    • Herbicide raw crystals
    • Custom fine chemical precursors for agrochemical OEMs

    5. Specialty Chemical Photographic Developers

    Photographic material producers use glyoxime’s chelating characteristics in precision developer formulations for specialty imaging. In silver-based photographic systems, glyoxime controls background fog and enhances image resolution by selective silver scavenging during processing. Standards require batch traceability and rigorous moisture/purity checks to prevent unwanted side reactions affecting image quality or archival stability.

    Industry compliance standards

    • ISO 18911 for photographic processing chemistry
    • ANSI IT9.2-1998 guidelines for photographic image permanence
    • ROHS compliance for restricted substances in developer chemicals

    Typical usage ratio

    • 0.05–0.2% by weight in developer concentrates; formulation depends on desired silver retention and processing time parameters

    Downstream process integration

    • Homogeneous blending into concentrated or ready-to-use developer fluids
    • Direct tank addition during film or print processing
    • Batch QC for silver ion binding efficiency and residue profiles

    Final product types

    • Industrial photographic developer fluids
    • Archival photographic processing kits
    • Custom imaging reagents for film manufacturing
    Free Quote

    Competitive Glyoxime prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

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    Certification & Compliance
    More Introduction

    Glyoxime: Value and Reliability from the Source

    Direct from the Manufacturer: Proven Integrity, Proven Results

    Glyoxime continues to prove indispensable for many chemical processes, and its reputation for reliability comes from a production process honed by generations of chemical engineering on our site. We manufacture glyoxime with clear intent: providing users with material whose identity and performance never leave room for doubts. This is not a commodity shuffled through anonymous intermediaries or changed hands so many times that its traceability runs thin. Here on-site, the process stays close and tightly supervised, from raw material to packaged product. For those working with glyoxime in demanding applications—analytical testing, organic synthesis, specialty reagent production—every bottle represents an assurance from the source. Traceability spans years, batches, and every logbook on our production line.

    Purity that Matches Industry Demands

    Many customers expect reproducibility batch after batch. Our team never leaves purity to chance. Typical specifications for glyoxime lie in the range above 99%. Our QC team reviews every lot with a battery of tests: melting point, elemental analysis, and NMR. Years ago, some producers cut corners, treating high purity standards as negotiable. We learned early that quantitative and qualitative feedback from our industrial and laboratory users built the backbone of our process improvement. Feedback does not always come with a congratulatory note; sometimes, a customer flagging an unknown impurity or trace residue alerts us to an upstream variable. We keep those channels open, examining every concern closely and closing any gaps quickly. Our quality track record reflects evidence, not promises.

    Comparing Glyoxime to Related Chelating Agents

    Lots of companies float competing chelating agents, especially for the separation of nickel and palladium. In the field, the most common comparison crops up between glyoxime and its cousin, dimethylglyoxime (DMG). Some academics argue that DMG suits aqueous extractions a little better due to its solubility profile. Through years of customer trials and case studies, we notice a more nuanced reality: our glyoxime can deliver superior selectivity in alcoholic and mixed-phase environments, especially where users want to modulate reaction kinetics or optimize for minimal side product formation. Not every laboratory cares about these details. Specialized industries—battery component makers, metal refiners, research organizations—come to the direct manufacturer because they expect these minor differences to cascade into meaningful technical benefit.

    Other manufacturers often group glyoxime with generic oxime mixtures, but that misses the unique stability profile of our material. Consistency in chelation performance hinges on small but measurable distinctions in the glyoxime structure and residual solvent content. We support assays in multiple countries, recognizing every market may apply its own analytical priorities. If a minor excipient or stabilizing impurity creeps in, we spot it with our own methods and share the data openly. Few re-packagers control their glyoxime at this level. We understand the laboratory headaches caused by an unexpected peak in HPLC readouts, so we keep the glyoxime stream pure and the feedback honest.

    Applications: More Than Just the Sum of Reactions

    Specialist users in metallurgy look for glyoxime because of its strong nickel affinity. Our customers run metal analysis on site, sometimes in harsh field environments far from city laboratories. They count on our product to react efficiently without contaminating traces—whether their day involves testing mine samples, verifying plating baths, or identifying recycling stream impurities. Glyoxime’s precise metal complexation makes it a valued reagent in environmental monitoring programs. The demand from such programs led us to refine our drying and packaging steps: reducing water content, protecting against atmospheric contamination, and maintaining an unbroken chain of storage stability. Not every producer invests in these refinements. That is why regulatory agencies and accredited laboratories often insist on glyoxime sourced from a factory with this record.

    A smaller but growing application comes from organic synthesis. Glyoxime sometimes gets used in the creation of ligand frameworks and specialty catalysts. Over time, requests arrived at our door from universities and process chemistry teams needing not just bulk powders but solution-phase forms tailored for direct dosing. We responded by building modular reaction suites and integrating packing automation, minimizing cross-batch contamination and meeting small-lot purity demands. Ask anyone synthesizing technical intermediates—they prefer to talk to the people who really make the compound, not a voice reading a price list. Direct feedback led us to broaden our variant portfolio. While we keep our primary glyoxime line laser-focused on purity and stability, we now offer special particle-size cuts and custom blending as one-offs for researchers with challenging targets.

    Model and Specification: Born On-Site

    Our main glyoxime product uses a model code derived from internal batch records—this isn’t a generic or foreign import relabeled for a quick sale. Each batch number and model code reflects not just an internal reference but a record of exact parameters: pH endpoints, residual moisture, crystallization temperature, even details about which reactor line produced it. We train our technical staff to keep these logs complete. Customers who request a certificate of analysis see direct printouts from our production records, not summaries rewritten for sales gloss. Any deviation, anomaly, or special processing gets logged, even if the batch passes all outgoing checks. Model traceability helps users match historic performance to current deliveries; this level of recordkeeping sets us apart from anonymous trading houses or general-purpose distributors.

    Some manufacturers sell glyoxime as a side product of unrelated operations, creating variable quality. Our approach centers on dedicated lines producing only glyoxime and related oximes. The team oversees every phase: solvent purchases, filtration stages, particle collection, drying, and packing. Insights from previous batches steer real-time adjustments—tightening drying times in high humidity, tuning crystallization rates when ambient temperatures push the process toward less uniform crystals. Reproducibility improves with focus. We make our batches for demanding use, whether the end site is a certified testing lab or industrial-scale process unit. Technical documentation, spectra, and compliance profiles remain updated per batch and easily accessible—not lost in a sea of undifferentiated data.

    Differentiation: The Difference a Manufacturer Knows

    One aspect often missed by new customers comes from the nature of supply chain integrity. Trading houses typically label chemical drums and kegs with basic compliance codes and a few generic identifiers. As the manufacturer, we’re expected to know exactly how our glyoxime was made, handled, tested, and stored—no gentle assumptions, no fragmented handovers. This close relationship with the product gives our technical service team a unique position: we answer questions about thermal stability, crystal habit, or even byproduct trace levels with reference to decades of real cases.

    Product consistency goes beyond specification sheets. At our site, we fine-tune the crystallization step to tune granularity for different user preferences. Some metal labs want a powder that disperses instantly in alcohol. For those teams, we set up a separate isolation tank and dedicated grinding stage. Subtle shifts in the polymorphic form influence solubility, and our steady process control lets users trust that no variation will derail their workflow. Feedback cycles with key clients prompted us to revisit everything from desiccant selection to the fine points of moisture-protected packaging. Half of reliability boils down to small things—like finding less clumping on a humid day because we adjusted drying curves, or skipping an unwanted co-solvent spike due to a small tweak in purification.

    Real-World Impact and Customer-Driven Change

    Discussion rarely stops at purity or grade. Most users value communication with the source above all. Last year, a leading environmental firm flagged an issue in a new lot—a borderline off-spec water content, only apparent when their sensor suite pushed past normal humidity readings. Our in-house team backtracked every process stage, isolated the cause in the drying section, and shared the fix with all client partners. This doesn’t happen at a reseller’s office. Awareness of process history, flexibility to adjust in real time, and sharing detailed root cause analysis all create reliability users notice in daily operation.

    Many customers in mining, electroplating, or environmental monitoring stick with a supplier for one reason: consistency during process upsets or changing regulatory demands. Our chemists work side by side with users updating method parameters, not hiding behind generic disclaimers. During supply chain disruptions, our on-site raw material reserves matter. We don’t chase lowest global prices at the expense of authentic batch records or identity. Years of direct supply have built trust through transparency and open data. New users join our list because they want more than a number on a catalogue—they want proof of origin and assurance the next shipment matches the last, whatever the market scenario.

    Meeting Market Regulations and Industry Evolutions

    Regulatory landscapes keep moving. National standards for analytical reagents evolve faster than many producers can update software or quality practices. We keep our staff up-to-date with compliance training and direct interaction with regulatory bodies. When a new test method for nickel analysis appeared, we retooled internal QC to reflect the tighter tolerances. Regulatory bodies value stability not just of product but of documentation, so we aligned traceability systems for full backward review—the kind demanded when audits go deeper than basic paperwork. Buyers in critical applications expect more than a generic certificate: they want real certificates, traceable signatures, batch maps, and unredacted process histories.

    We continually audit every supplier, check every raw input, and recalibrate internal standards at a frequency that exceeds statutory minimums. This uncompromising stance has occasionally forced delays, but our partners appreciate that a slow, correct batch beats a fast, problematic one. Few middlemen respect this lesson, chasing speed at every opportunity and treating the inevitable recall or contamination as a cost of doing business. We live with the product long after it leaves our gates—which is why full compliance isn’t a marketing claim but a daily reality.

    Continuous Improvement: Listening and Adapting with Stakeholders

    True improvement comes from feedback. Every year, technical staff visit the largest users of glyoxime, sharing process updates and listening to field realities. Adjustments in crystal size, changes in water content, or packaging modifications often originate from these discussions. Problems rarely present clearly in laboratory tests; only those who manufacture the product and examine how it gets used in the field connect the dots. This is the backbone of continuous improvement.

    We stay ready to adjust synthesis conditions based on evolving user needs. When a customer in Latin America required ultra-low dust powders for their automated feed lines, our team built a new pneumatic handling station. For a European research group seeking an alternative packing size, we adapted our process bottling to ensure shorter storage and minimal transfer risk. These practical changes seldom make it to glossy catalogues, but anyone who uses chemical products day in, day out, knows their value. Small irritations—such as static charge in a dry room or caking from humidity—get solved fastest when solutions come direct from those who handle every stage.

    Environmental Responsibility and Production Integrity

    Manufacturers stand responsible for not just what leaves the factory, but what doesn’t show up in emissions and waste. Our synthesis process now features closed-cycle solvent recovery, sharply reduced wastewater output, and a measured reduction in atmospheric venting over the last five years. These investments matter to all involved. More regulatory authorities scrutinize both process carbon footprint and final waste profile; glyoxime leaves our site with clear documentation and full environmental logs. Third-party audits reinforce that our procedures actually match the commitments we publicize. We’ve invested in automated emissions monitoring precisely because users, communities, and authorities want real evidence, not generic assurances.

    Responsibility extends beyond compliance to stewardship in sourcing precursors and managing byproducts. Reclaimed solvents go back into the process loop. Solid residues undergo full compositional analysis before responsible disposal or recovery. Some glyoxime producers export the waste and let downstream handlers worry about impact; we keep our end-to-end lifecycle on-site as far as technically feasible. Our staff receive hands-on environmental monitoring training and participate directly in community liaison groups. Internal reviews happen not because regulations demand them, but because real-world neighbors and customers expect more than minimum standards.

    Technical Support that Understands the Product

    Whether the question arises from a field technician in remote mining operations, a university research fellow, or a process chemist at a large plant, our technical support never runs short on detail. Years of direct process improvements and on-site troubleshooting taught us that an answer rooted in hands-on reality beats theory alone. Our engineers know how each glyoxime batch came to be, what differences arise from drying variance, and which steps most influence metal complexation rates. When users push our glyoxime to its technical boundaries, we listen and adapt. Case logs inform future batch tweaks, and even the smallest lessons get added to our internal library for all staff to access.

    Support continues beyond initial sale. Repeat customers rely on technical visits for on-site advice—whether re-engineering extraction set-ups, fine-tuning analytical routines, or problem-solving novel reagent interactions. Industry trust grows by evidence: clear record-keeping, honest post-delivery follow-up, and a habit of integrating customer experience into manufacturing changes. Our ongoing commitment is to provide more than just a product; we deliver the backing and knowledge that only the originator can offer.

    Forward-Looking Approaches to Glyoxime Production

    Market pressures shift all the time. New extraction techniques, more sensitive analytical instruments, and changing end-user requirements keep pushing standards upward. Our manufacturing philosophy recognizes this by investing year after year in incremental upgrades—automated monitoring, in-line QC, process analytics to keep every gram of glyoxime within tighter tolerances. While some supply chains chase temporary price drops, dedicated manufacturing means keeping a steady hand on quality, batch after batch.

    We rarely chase trends for their own sake. Instead, improvements focus on points where user outcomes improve: fewer incidents of field failure, smoother integration into automated systems, longer shelf stability, and tighter control over trace contaminants. The best innovations stick when they’re rooted in direct production experience, not speculation. Direct user visits and transparent process walkthroughs give us the clearest path for continuous upgrade.

    In the end, the difference between a product sourced from a true manufacturer and one picked off a reseller’s shelf shows up in the details. Every adjustment in process yield, every improvement in purity, every extra test run, builds reliability. Glyoxime remains a mainstay for technical applications where confidence is not negotiable. We stand by each batch because our name and experience go out the door with it—reason enough for those who value certainty to turn to the original source.