Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Fluorexon

    • Product Name Fluorexon
    • Alias Dibromofluorescein
    • Einecs 221-573-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    520126

    Chemical Name Fluorexon
    Cas Number 62669-70-9
    Molecular Formula C37H34N2Na2O9S2
    Molar Mass 792.79 g/mol
    Appearance Orange powder
    Solubility Soluble in water
    Excitation Maximum 495 nm
    Emission Maximum 520 nm
    Storage Temperature 2-8°C
    Synonyms Fluorescein brown, Fluorexon sodium salt
    Application Biological staining, indicator for calcium determination

    As an accredited Fluorexon factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Fluorexon is supplied in an amber glass vial containing 5 grams of orange powder, labeled with chemical details and safety precautions.
    Shipping Fluorexon should be shipped in tightly sealed containers, protected from light and moisture. It must be packed according to standard chemical shipping regulations, with proper labeling and safety data sheets included. Avoid extreme temperatures and physical shock during transit to maintain product integrity and ensure safe delivery.
    Storage Fluorexon should be stored in a tightly sealed container, away from light and moisture, in a cool, dry, and well-ventilated area. Avoid exposure to incompatible substances such as strong oxidizers and acids. Ensure the storage area is clearly labeled and restricted to trained personnel. Proper precautions should be taken to prevent inhalation, ingestion, or skin contact during handling and storage.
    Application of Fluorexon

    Applications of Fluorexon in Industrial Manufacturing

    Fluorexon, as a specialized fluorescent dye, demonstrates consistent performance in select industrial segments due to its unique spectral properties and chemical stability. We supply Fluorexon directly to manufacturing partners that require stringent process compliance and reproducibility in critical downstream workflows. Below, we provide an application-focused overview of deployment in authentic industrial channels.

    1. In Vitro Diagnostic (IVD) Reagent Manufacturing

    Medical diagnostics manufacturers utilize Fluorexon for the preparation of clinical IVD reagents, enabling precise fluorescent detection in laboratory analyzers. The dye’s stable emission in the visible range allows clear discrimination between test analytes during automated immunofluorescence and coagulometry assays. Our clients prioritize batch consistency for traceability within regulated production environments, integrating the dye during reagent blending based on specific kit requirements.

    Industry compliance standards

    • ISO 13485:2016 (Medical devices – Quality management systems)
    • Ce marking requirements for IVDs (EU Regulation 2017/746)
    • FDA 21 CFR Part 820 (USA, cGMP for Medical Devices)
    • China National Medical Products Administration (NMPA) IVD regulations

    Typical usage ratio

    • 0.05–0.2 mg/mL in working reagent solutions, adjusted per desired detection sensitivity and background interference; formulation titration validated during kit QC.

    Downstream process integration

    • Added during buffer solution compounding before antibody or protein conjugation steps; filtration and aseptic filling ensure dye stability throughout kit shelf life.

    Final product types

    • Clinical diagnostic kits for hematology, immunoassays, urinalysis, and infectious disease detection
    • Automated analyzer cartridge reagents
    • Quality control reference materials for laboratory proficiency testing

    2. Biomedical Research Reagents

    Research reagent suppliers apply our material for cell labeling, flow cytometry staining, and protein tracking in advanced biomedical protocols. Its broad applicability in fluorescence microscopy and multi-color flow cytometry depends on stable dye-protein conjugates, facilitating reliable quantitative analysis for life sciences R&D. We closely cooperate with partners to align purity and lot release criteria with assay validation protocols.

    Industry compliance standards

    • ISO 9001:2015 (Quality management system for manufacturing)
    • REACH Regulation (EC) No 1907/2006 for chemical safety in the EU
    • Good Laboratory Practice (GLP) relevant to research consumables
    • Material Safety Data Sheet (MSDS) compliance in global jurisdictions

    Typical usage ratio

    • 1–25 μg/mL in staining protocols; labs determine exact concentration by target cell density and required fluorescence intensity.

    Downstream process integration

    • Mixed with antibody or protein conjugates during late-stage labeling; subsequent buffer exchange and QC purification are standard prior to shipment as pre-formulated research reagents.

    Final product types

    • Flow cytometry antibody-fluorophore conjugates
    • Cell tracking and viability assay kits
    • Multi-well plate screening reagents for high-content imaging

    3. Ophthalmic Diagnostic Solutions

    Ophthalmic formulators incorporate Fluorexon as a diagnostic coloring agent in products supporting corneal and contact lens evaluations. Its distinct green fluorescence under cobalt blue light enables practitioners to visualize lens fitting, tear film behavior, and ocular surface irregularities. We control trace contaminant profiles to meet pharmacopeial grade and ensure the dye’s compatibility in aqueous eye solutions with appropriate osmolality and pH control.

    Industry compliance standards

    • Ph. Eur. 11.0 (European Pharmacopoeia – Ophthalmic Preparations)
    • USP Chapter <771> (Ophthalmic Products – Quality Tests, United States)
    • ISO 8599:2014 (Ophthalmic instruments — Slit-lamp microscopes)
    • ICH Q7 GMP for active pharmaceutical ingredients used in medical devices

    Typical usage ratio

    • 0.1–0.2% (w/v) in diagnostic ophthalmic solutions, titrated to balance visibility and patient comfort for each brand’s lens fitting methodology.

    Downstream process integration

    • Introduced during blending of saline-based formulations before sterile filtration and unit-dose filling; supported by stability and sterility assurance through final release testing.

    Final product types

    • Contact lens fitting solutions for optometrists
    • Corneal integrity diagnostic drops
    • Pre-filled ophthalmic applicator vials

    4. Plasma Separation Membrane Manufacturing

    Manufacturers of diagnostic test strips for blood analysis implement Fluorexon as a membrane marker to control and evaluate plasma separation efficiency. Its vivid color under specific reading windows supports quality inspection steps, confirming successful capillary flow and separation in rapid test cassettes. We offer technical support for integrating the dye into diverse polymer matrices used in disposable strip assembly lines, ensuring stability without migration or interference in downstream immunochemical reactions.

    Industry compliance standards

    • ISO 13485:2016 and ISO 14971:2019 (Risk management for medical devices)
    • EN 13612 (Performance evaluation of in vitro diagnostic medical devices)
    • China YY/T 0466.1-2016 (Medical device labeling and traceability)
    • Good Manufacturing Practice (GMP) for medical device components

    Typical usage ratio

    • 10–80 ppm in membrane coating formulations; adjusted according to membrane thickness, capillary dimensions, and visual inspection requirements.

    Downstream process integration

    • Applied during impregnation of separation membranes prior to strip lamination; UV-curing or solvent-drying secures marker retention and allows in-line QC validation during roll-to-roll manufacturing.

    Final product types

    • Disposable blood diagnostic strips
    • Capillary flow-based POCT (Point-of-Care Testing) cassettes
    • Membrane cards for serum/plasma separation in laboratory automation

    5. Textile Anti-Counterfeiting Markers

    Textile processing plants leverage Fluorexon as an authentication tracer, embedding invisible fluorescent signatures into specialty fibers or finishes. The dye activates under dedicated wavelength detectors, creating a verifiable identity for branded apparel, security uniforms, and industrial wear. This integration occurs during controlled dyeing or coating stages, guided by customer-specific traceability contracts. We offer tailored particle size distributions and dispersibility to suit high-throughput continuous machinery, meeting required regulations for non-toxic and skin-safe contact.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (Textile safety)
    • EU REACH Regulation Annex XVII (Restriction on hazardous substances)
    • GB 18401-2010 (Chinese National Textile Safety Standard)
    • ISO 17025 for analytical verification of marker authenticity

    Typical usage ratio

    • 5–50 ppm in fiber or surface treatment baths; dosage optimized per fabric weight and detectability targets, with routine checks for uniformity and invisibility.

    Downstream process integration

    • Dispersed in dyeing liquor or applied during finishing line treatments; fixation via heat-setting or UV exposure creates lasting security without affecting fabric hand-feel.

    Final product types

    • Brand authentication textiles (garments, uniforms, security labels)
    • Industrial technical fabrics with covert markers
    • License-protected merchandise and ad specialty textiles
    Free Quote

    Competitive Fluorexon prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing Fluorexon: Fluorescent Dye Crafted With Precision

    Our Commitment To Quality Shines With Fluorexon

    In the chemical industry, every product is a direct reflection of the people and processes behind it. With Fluorexon, our team set out to create a fluorescent dye that delivers reliability and purity to scientists and engineers who need more than another off-the-shelf colorant. We have watched the challenges faced by biological researchers, clinical diagnosticians, and industrial labs that require highly dependable markers—especially for high-sensitivity applications like trace protein staining or ophthalmic surgery.

    Fluorexon, often recognized by its index number CI 45350, stands out for its bright yellow-green emission in aqueous media. We manufacture it under strict adherence to consistency standards: our batches undergo validation via spectroscopic analysis and chemical testing before release. Each run is documented, so traceability and reproducibility are never left to chance. We believe transparency matters as much as technical quality.

    Fluorexon’s Chemical Structure and Its Impact

    Fluorexon’s chemical nature comes from its xanthene dye backbone, a structure that supports a strong absorbance around 490 nm with fluorescence emission close to 520 nm. This pattern gives it a clear advantage over weaker, less stable dyes like conventional fluorescein sodium. Since any impurity or batch deviation may impact fluorescence performance or biocompatibility, our synthesis routes exclude heavy-metal catalysts. In our experience, even trace metal contamination alters sensitivity in downstream immunoassays. We use instrumental methods—such as ICP-MS and HPLC—to confirm the absence of such impurities.

    Applications That Depend On Precision

    Fluorexon sits at the core of two worlds: clinical diagnostics and molecular biology. In hospitals, ophthalmologists use Fluorexon in slit lamp examinations to visualize corneal abrasions, contact lens fits, or tear film breakup without the excessive staining of standard fluorescein. We supply the same Fluorexon trusted by clinics for these real-world challenges, never compromising purity or solubility.

    In the research sector, Fluorexon marks proteins, nucleic acids, and even live cells for visualization by fluorescence microscopy or flow cytometry. Its stability in alkaline buffers and resistance to photobleaching allow extended imaging, which is crucial for time-lapse studies or automated plate readers. We engineered our product for minimal batch-to-batch drift, keeping emission intensity steady, so results remain comparable between experiments.

    What Sets Fluorexon Apart From Other Fluorophores

    Lab professionals talk about “signal-to-noise ratio” and “background interference” because not all fluorescent dyes behave equally under real conditions. Some dyes leach contaminants or degrade under repeated illumination, creating signal loss, false positives, or high background. With Fluorexon, we handle these issues at the manufacturing level. From raw material selection to final package sealing, we monitor every step. This vigilance means researchers and clinicians avoid time-consuming troubleshooting, whether they use our product for diagnostic test development, water tracer studies, or education.

    Competitor dyes may substitute quality for cost, but our customers tell us that predictable performance and bio-compatibility matter most. In diagnostic kit production, for example, minor impurities can create erratic calibration curves. We use analytical reference solutions and test our dyes directly in end-use matrices, going beyond in-house QC. Our focus stays on end-user results, not only internal benchmarks.

    We avoid broad spectrum preservatives or excipients that interfere with common biological workflows—this is based on direct feedback from our partners running sensitive ELISAs and protein arrays. We maintain a consultative relationship with lab managers who’ve shared their experiences with sample carryover, precipitation, or filter clogging caused by inferior dye formulations in the past. Our technical support reflects years of practical lab troubleshooting, not just theoretical expertise.

    Handling And Shelf-Life Built For Real-World Demands

    Shelf stability should never become a guessing game. Our Fluorexon powder and solution forms hold their fluorescence for tough shipping and variable storage, surviving temperature excursions that challenge weaker products. Each lot leaves with a real expiration date, confirmed by accelerated and long-term aging studies. We log batch performance in clinical and environmental labs, updating protocols as data comes in.

    Static clumping and moisture exposure can cripple even the best production runs if packaging is handled carelessly. That’s why we invest in moisture-impermeable, tamper-evident vials and multi-layered pouches. Powder remains free-flowing, with no surprises at the bench. Solution users benefit from aliquot-appropriate volumes that minimize airspace, guarding against photodegradation. We also supply dark-glass containers, maintaining photostability until the last use.

    Safety And Compliance: Lessons From Experience

    Fluorexon’s safety profile drives our shipping and handling protocols. We know from extensive, long-term studies and market surveillance that allergic reactions are rare, but possible—especially in direct ophthalmic applications. So we print clear ingredient listings and include relevant hazard and precautionary statements, working with customers to answer safety questions based on real exposures, not just theoretical risks.

    In regulated markets, traceability and documentation accompany each order. We comply with REACH, local chemical notification, and applicable IVD standards. We provide certificates of analysis and material safety data, not as part of generic compliance, but because we value informed use. It’s a two-way process: feedback from clinician-users and industrial hygiene officers shapes our updates. This continual improvement goes beyond what any trader or distributor can promise.

    Supporting Science In Practice—Not Just On Paper

    Too often, products look the same on technical sheets but diverge in the lab. We work with reference laboratories, public health authorities, and university teaching labs. Our technical staff regularly perform hands-on demonstrations and method validations on site, connecting product chemistry to real application needs.

    Take the case of a high-throughput screening lab running automated fluorescence plate assays. After problems with evaporative drift and inconsistent signals, the team switched to our Fluorexon. Our technical engineers visited the lab, reviewed pipetting protocols, and established stability under local temperature and humidity. End-use feedback led to a packaging update that reduced waste and lowered per-experiment costs—evidence that practical partnerships improve scientific outcomes.

    Innovation That Respects End-User Needs

    Progress in the dye chemistry field demands more than new molecules; it needs better listening. Each improvement in Fluorexon’s formulation grows from sustained dialogue with customers grappling with real-world bottlenecks: instrument compatibility, interference from buffer components, or changing regulatory limits on preservatives. From sourcing through synthesis and finishing, our chemists and engineers stay responsive, balancing innovation with field-proven reliability.

    Our approach rejects the idea of “one size fits all.” Whether for cytometry, tissue marking, or microfluidics, we tailor specifications to customer protocols. We do not simply sell a chemical; we join the workflow. We engage with instrument manufacturers and diagnostic kit builders to clarify how Fluorexon interacts in multiplex systems or with signal amplification steps. This means customers get more than a product—they gain a manufacturing partner who solves lab challenges proactively.

    Fluorexon in Water Tracing and Environmental Science

    Outside clinical and laboratory use, Fluorexon proves valuable in water tracing. Environmental engineers, hydrologists, and municipal operators use its strong fluorescence to study water flow, infiltration, and pollutant dispersion. Our manufacturing expertise enables scale-up of large-batch deliveries, essential for field trials in riverine systems or municipal infrastructures. We provide supporting documentation and technical advice based on experience supplying public works departments, consulting engineers, and environmental monitoring agencies.

    Dosing accuracy in water tracing is critical, and poor solubility or inconsistent dye lots compromise results. We tune our production to avoid undissolved colorant clumps and unwanted by-products, which can confound spectrometer readings. Our experience with water treatment plants has shown that early-stage consultation prevents data losses, especially when working in complex matrices laden with organic and inorganic contaminants.

    Educational Partners And Inheritance Of Knowledge

    Fluorexon’s use in teaching institutions illustrates another side of our approach. Undergraduate chemistry and biology classes need reliable, visually impactful reagents that introduce students to hands-on laboratory science. Our product arrives with documentation written for educators—not just technical managers—reducing barriers for new instructors entering the field. Feedback from schools and educational suppliers frequently guides our packaging and lesson plan resources.

    We supply Fluorexon in quantities suitable for classroom demos and undergraduate labs, maintaining the same standards as in medical or research-grade stock. Our efforts reinforce a culture of reproducibility and attention to chemical hygiene, helping raise the next generation of scientists who respect both technique and safety.

    Addressing Supply Chain Pressures And Contingency Planning

    Supply chain reliability determines the pace of innovation in research and diagnostics. Chemical shortages from disruptions or overreliance on vulnerable upstream processes have hit our sector more than once in recent years. As the original manufacturer, we invest in redundancy—not just in raw material sources, but also in process validation and finished goods inventory.

    The agility to scale production has allowed our partners to expand their diagnostic or research offerings without fear of critical shortages. During the past decade, we’ve faced massive surges in medical demand and adapted with increased production shifts and local warehousing. Communication with our users kept lead times and quality in check; these experiences reinforce the value of manufacturer-direct partnerships during times of stress.

    Practical Solutions To Industry Challenges

    Real-world applications rarely unfold as expected, and trouble-shooting rarely follows a script. Our support network includes veteran chemists and technical specialists, many of whom have worked in academic, clinical, and industrial settings before joining our team. This practical background informs our technical guidance—whether for dye solubility, spectral compatibility, or buffer interactions. Beyond documents, our staff offer advice on optimizing protocols and resolving unexpected troubleshooting issues.

    From personal experience, batch variability and contaminant profile leave lasting impacts in protein detection, environmental monitoring, or assay kit manufacturing. Too many off-brand products sacrifice these subtleties for price or volume. By focusing on in-process control, careful analytical verification, and end-user collaboration, we ensure that each batch of Fluorexon stands up to real critical scrutiny. We back our claims with open analytical data and are ready to walk through challenges side-by-side with our customers.

    Looking Forward: Responsibility and Collaboration

    Fluorexon is the work of decades of chemical expertise, continuous improvement, and respect for user feedback. Our quality benchmarks grow from hard lessons in manufacturing, research, and user support—not from theory or marketing alone. In every sector—medical, research, environmental, educational—we build long-term relationships, treating our customers as partners in progress.

    As demands for brighter, more reliable, and safer dyes increase, we continue to invest in both technology and people. Instead of pursuing every possible market, we draw lessons from real users, consult on applications before and after purchase, and refine our approach. Our reputation comes from consistency, technical partnership, and the belief that real manufacturing expertise—in the plant and at the bench—remains the hidden infrastructure of science.

    The Manufacturer’s Promise

    Fluorexon benefits from the attention to detail and practical knowledge that only a direct manufacturer can provide. From raw ingredient sourcing and process validation to technical support and after-sales problem-solving, our focus never shifts from the needs of those who build, discover, diagnose, and teach with our products. We invite feedback, share data, and stand prepared to address emerging requirements in a world of changing science. This hands-on, iterative process gives us confidence that Fluorexon remains the trusted choice for fluorescence-driven applications.