Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Flumequine

    • Product Name Flumequine
    • Alias Flumiquine
    • Einecs 254-484-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    819601

    Name Flumequine
    Cas Number 42835-25-6
    Molecular Formula C14H12FN3O3
    Molar Mass 289.26 g/mol
    Drug Class Quinolone antibiotic
    Appearance White to pale yellow crystalline powder
    Mechanism Of Action Inhibits DNA gyrase
    Usage Primarily in veterinary medicine
    Route Of Administration Oral
    Solubility In Water Slightly soluble
    Melting Point 199-202°C
    Storage Conditions Store at room temperature, away from light and moisture

    As an accredited Flumequine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for Flumequine features a white plastic container labeled "Flumequine 500g," with safety instructions and hazard symbols clearly displayed.
    Shipping Flumequine is shipped in tightly sealed containers, protected from light and moisture. It should be transported at room temperature and handled with care to prevent contamination or spillage. Proper labeling and compliance with local regulations are essential to ensure safe and secure delivery of this veterinary antibacterial agent.
    Storage Flumequine should be stored in a tightly closed container, protected from light and moisture. Keep it at room temperature, ideally between 15°C and 25°C (59°F–77°F), in a dry, well-ventilated area away from incompatible substances such as strong oxidizing agents. Ensure proper labeling and restrict access to authorized personnel. Avoid exposure to excessive heat or direct sunlight.
    Application of Flumequine

    Applications of Flumequine in Industrial Manufacturing

    Flumequine, a synthetic quinolone compound, plays a specialized role in veterinary and aquaculture applications. As an original manufacturer, we understand customer demand for reliable sourcing, regulatory conformity, and support across complex formulation and production processes. Below, we detail several established downstream sectors where our material contributes to final product value, with transparent reference to compliance, formulation guidance, manufacturing stages, and the resulting commercial goods.

    1. Veterinary Injectable Solutions for Food Animals

    Veterinary pharmaceuticals routinely use flumequine as an active antibacterial ingredient in formulations for injectable solutions treating systemic infections in food-producing livestock, particularly bovines and swine. Leading animal health producers align manufacturing to regional residue limits and veterinary drug monographs, carefully dosing flumequine for therapeutic levels matched to specific animal weight and infection patterns.

    Industry compliance standards

    • EU Regulation (EC) No 470/2009 for veterinary medicinal product MRLs
    • Chinese Veterinary Pharmacopoeia (current edition)
    • European Pharmacopoeia (Flumequine monograph 01/2017:1766)
    • WHO Guidelines on Veterinary Drug Residues in Foods
    • Good Manufacturing Practice (GMP) for veterinary products

    Typical usage ratio

    • 2% to 10% w/v as the active substance within the injectable solution, adjusted per species and clinical protocol

    Downstream process integration

    • Dissolved into sterile, buffered solvent systems under aseptic conditions following micronization and quality control; solution sterilized and aseptically filled into multidose or single-use vials

    Final product types

    • Veterinary injectable solutions for swine, cattle, and poultry leaving certified finished dosage form facilities

    2. Aquaculture Medicated Feed Additives

    Producers of medicated fish feeds leverage flumequine’s activity against Gram-negative pathogens affecting farmed species. Integration into pelleted or extruded feed matrices requires careful adherence to residue legislation, with precise dosing protocols for target aquatic species and withdrawal timelines set for commercial seafood safety.

    Industry compliance standards

    • US FDA 21 CFR Part 558 (New Animal Drugs for Use in Animal Feeds)
    • Japanese Positive List System for Agricultural Chemical Residues in Foods
    • Codex Alimentarius: MRLs for aquaculture drugs
    • EU Decision 2003/181/EC (Maximum Residue Limits in aquaculture)

    Typical usage ratio

    • 30 mg to 50 mg active per kg finished feed (0.003%–0.005%), titrated to species, biomass, and prescribed treatment period

    Downstream process integration

    • Premix with carriers prior to homogeneous distribution within steam-conditioned mash; ensures uniform dose in final pellets or extrudates, followed by moisture removal and cooling

    Final product types

    • Medicated feed pellets for salmonidae, tilapia, and shrimp for commercial aquaculture

    3. Oral Veterinary Suspension Preparations

    Suspension preparations for veterinary use utilize flumequine as an oral antibacterial agent for treating enteric and systemic infections, particularly in calves and piglets. Formulators must ensure particle size and suspendability for accurate oral dosing, maintaining stability in multi-dose bottles for livestock producers.

    Industry compliance standards

    • European Pharmacopoeia (Flumequine substance standard)
    • Veterinary Drug Administration Regulation (China)
    • OIE (World Organisation for Animal Health) guidelines for antimicrobial use in animals
    • GMP for Finished Veterinary Products

    Typical usage ratio

    • 5% to 20% w/v in the final suspension, determined by veterinary prescription and species-specific requirements

    Downstream process integration

    • Suspended in aqueous vehicle with appropriate viscosity modifiers and preservatives; rigorous testing for sedimentation rate and dosing accuracy precedes batch filling into dosing bottles

    Final product types

    • Oral suspensions for ruminant and swine veterinary healthcare markets

    4. Tablet and Bolus Manufacturing for Livestock

    Animal health manufacturers employ flumequine as the API in compressed tablet and bolus forms intended for large-scale livestock dosing. The process demands stringent validation for uniform API distribution and dissolution, meeting residue standards enacted for meat and milk safety in major export markets.

    Industry compliance standards

    • Current Good Manufacturing Practices (cGMP) for medicated feed and drug manufacturers (FDA, EU)
    • VICH GL36 (Veterinary International Cooperation on Harmonization of Technical Requirements for Registration of Veterinary Medicinal Products)
    • Relevant limits in Codex Alimentarius and local residue monitoring schemes
    • National/Regional Pharmacopoeias (e.g., BPV, EP)

    Typical usage ratio

    • 10% to 25% w/w in single bolus formulations, customized to animal category, weight, and designed release profile

    Downstream process integration

    • Granulated with proper excipients for flow and compaction, followed by high-pressure compression into tablets or boluses; in-process QC for weight variation and uniformity of content

    Final product types

    • Dose-adjusted tablets and boluses for cattle, sheep, and large livestock, supplied for veterinary intervention on-farm and via vet clinics
    Free Quote

    Competitive Flumequine prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing Flumequine: Insights from the Production Floor

    The Story Behind Flumequine Manufacturing

    In our industry, precision stays at the core of everything we do, especially with a compound like Flumequine. With decades of hands-on manufacturing experience, my team and I have seen Flumequine evolve alongside changing veterinary needs, regulatory frameworks, and customer expectations. Every batch we produce leaves our facility only after passing standards that stem not just from external regulations, but from a commitment that comes from understanding what livestock farmers, aquatic medicine users, and veterinarians genuinely need.

    Flumequine belongs to the quinolone class, recognized for its reliable antibacterial capabilities. We produce it as a crystalline powder, most often supplied as an off-white to pale yellow substance. Moisture content and particle size distribution come under tight scrutiny. This is not about chasing perfection for perfection's sake; it’s a response to real-world feedback from field practitioners who have faced the frustrating consequences of inconsistent mixing or unreliable dissolution rates in their applications.

    Producers and end-users in the veterinary world often echo the same sentiment: predictability makes all the difference. Our Flumequine batches typically show assay values above 98.5% and carry minimal impurities, a factor that gives veterinarians confidence to dose accurately. Controlling for heavy metals, residue solvents, and other trace contaminants is not just about ticking boxes—many aquaculture operations protect valuable stock that can be instantly affected by minor quality variations.

    Where Flumequine Delivers Results

    Over the years, we have fielded questions and advice requests from all corners—poultry farms concerned about E. coli control, fish farmers responding to outbreaks of Aeromonas hydrophila, and swine integrators facing Salmonella challenges after transport stress. Make no mistake, selecting the right antibacterial often shapes the outlook of an entire operation, both in health outcomes and in staying on the right side of regulatory guidelines.

    Flumequine routinely serves in oral dosage forms, such as medicated feed premixes or drinking water solutions. During manufacturing, we focus not just on the high purity of the active, but also on achieving proper flow and dispersibility. Early batches in our history sometimes generated customer complaints about clumping or slow dissolution, especially in cold water on fish farms during winter cycles. We learned to fine-tune micronization to yield a free-flowing powder that disperses evenly, minimizing waste and ensuring the full intended dose reaches the animals. You’re not paying for a label; the expectation is a finished product that does precisely what the literature claims.

    Some manufacturers try shortcuts, blending lower grade material or failing to invest in robust in-process controls. All too often, this results in uneven distribution when mixing with feed or water, and it becomes spotty uptake. Our process ensures batch-to-batch consistency, not just to match an analysis certificate but to reflect the practical reality faced by the end user every day.

    Specifications and Practical Details

    Our Flumequine model is defined by quality standards shaped through long-term collaboration with industry experts, veterinarians, and feed integrators. Flumequine in our lineup is manufactured under GMP guidelines, with rigorous in-house testing at every critical stage. Loss on drying remains below 1%. We ensure very low levels of related substances, staying well within international norms as defined in most pharmacopeias. Most users do not care about minor differences in appearance, but we have learned that the feel and texture of the powder actually matters in bulk handling—slight granulation or poor powder flow can slow a production line or, worse, create non-uniform animal dosing.

    We have devoted significant R&D to studying how Flumequine interacts with common feed ingredients and drinking water treatment protocols across different livestock species. In field trials, our standard model performed well both as direct feed medication and as a premix additive. It shows optimal stability in typical feed pelleting environments and retains efficacy even when exposed to the higher temperatures of commercial feed manufacture. This difference matters to large operations distributing medicated feed over several days; active loss during preparation means a risk of therapeutic gaps and incomplete bacterial control.

    Our packaging accommodates operational realities. We typically supply Flumequine in fiber drums with double PE liners or high-barrier plastic packs, depending on region and customer requirements. We don't take shortcuts with packaging quality because oxygen and moisture intrusion can cut shelf life and degrade surface appearance. Customers operating in humid climates have shared horror stories of other brands arriving caked together; we synthesize and pack with those challenges top-of-mind.

    How Flumequine Compares: Key Differences from Other Choices

    Veterinary professionals have choices among the quinolone family. Enrofloxacin and oxolinic acid, for instance, surface in the same operational spaces. Yet Flumequine usually stands apart in clinical specificity and safety profile. It shows strong activity against a range of gram-negative bacteria—including Pasteurella and even some atypical infections—while demonstrating a predictably low incidence of side effects in target animals when veterinarians follow dosing guidance.

    Compared to fluoroquinolones like enrofloxacin, Flumequine tends to reach effective concentrations in plasma and tissue more consistently in certain fish and avian species, based on our customer reported feedback and published pharmacokinetic studies. Some countries now restrict the use of newer fluoroquinolones due to rising antimicrobial resistance concerns, but maintain regulatory pathways for Flumequine in specific applications. Responsible use remains key. Our technical consultants often join clients during audits or compliance checks, so we know firsthand what regulatory officers seek when they review sourcing and paper trails.

    Direct comparisons with oxolinic acid reveal further differences. Flumequine displays a broader spectrum of activity and a different metabolic pathway that influences residue depletion times. In chickens, for example, Flumequine shows favorable withdrawal intervals, making it an attractive choice for operations that must regularly rotate flocks without long layovers.

    As far as user handling goes, Flumequine demonstrates lower dustiness than some other quinolone powders—our process minimizes respirable particles, drawing from practical lessons learned after feedback from farm hands and mixing room operators. User safety depends on product properties. The powder form we offer needs only standard protective gear, and our on-site safety team conducts regular inhalation and skin sensitivity risk assessments.

    Troubleshooting and Real-World Challenges

    Anyone running a commercial operation knows that not every problem can be solved with over-the-phone troubleshooting alone. With Flumequine, common pitfalls surface from improper storage, cross-contamination in transport, or substandard mixing practices. Early in our manufacturing journey, we fielded reports of reduced batch potency linked to high-heat shipments. We responded by revising our logistics chain, adding temperature data loggers, and upgrading storage spaces in partner warehouses. Fewer complaints reach us now, but we encourage all users to inspect incoming shipments for signs of moisture or discoloration before accepting delivery.

    Use abuses sometimes come to light—cases where higher-than-labelled doses were given, either because of miscalculations or lack of staff training. Flumequine’s margin of animal safety, referenced in peer-reviewed studies, sets it apart from more toxic alternatives; still, we consider it critical to emphasize proper dosing each time we work with new buyers or conduct on-farm seminars. Overuse risks fostering resistance—a concern that looms larger with each passing year, especially as monitoring regulations grow tighter in nearly every export market. In partnership with veterinarians, we routinely sponsor seminars on prudent antimicrobial stewardship, not just to protect market share but to help underpin long-term viability for veterinary products as a whole.

    Another persistent challenge resides in adapting formulations to changing feedstuff trends—fish feed composition has shifted toward higher plant protein content, altering how medicated powders interact during mixing. We continuously re-evaluate fine-tuning requirements for dispersibility and solubility. Some clients have requested demonstration tests at their own mills, insisting on side-by-side comparisons against competitor products. To date, our Flumequine batches have consistently shown superior blend consistency and retention of label claim potency throughout storage, provided standard environmental controls are maintained.

    Supporting Facts and Compliance Realities

    No manufacturer functions in isolation from the regulatory environment. In our facilities, quality assurance teams track every lot of Flumequine from raw material check-in through to finished product release. Robust documentation and regular third-party audits underpin our processes. We don’t stop there—annual participation in proficiency testing schemes keeps our in-house analytics calibrated and transparent. Our internal monitoring includes not only final product, but also line cleaning and air quality controls, reducing the risk of contamination by other veterinary actives sometimes run in parallel production. A few years back, one customer flagged a suspected cross-contamination issue; after thorough investigation and independent laboratory retesting, we implemented even tighter line-clearance protocols and invested in additional dedicated equipment for Flumequine.

    International regulatory frameworks influence both formulation and labeling. Our headquarters tracks annual updates for residue tolerances, authorized uses in aquaculture and food-producing animals, and acceptable daily intake values. We often modify production runs to supply region-specific material, so the Flumequine used in Europe might differ slightly from lots destined for East Asia, reflecting the patchwork of local requirements. Global harmonization initiatives continue to benefit large-scale producers, but every market still has its quirks.

    All product literature includes definitive, field-validated withdrawal periods and clear instructions for use, distilled from trials carried out both in-house and at third-party academic facilities. We remain straightforward about the scientific basis behind every claim—no fancy marketing jargon, just plain reporting of what Flumequine does under actual farm conditions. Our practical orientation comes from years of open feedback loops with customers who measure success in flock health and yield, not in packaging graphics or broad adjectives.

    Industry Trends, Environmental Responsibility, and the Future

    Recently, the conversation across the veterinary pharmaceutical sector shifted more toward sustainability and careful stewardship. As raw material sources came under scrutiny, we assessed our own supply chain for traceability and environmental risk. Flumequine production involves several synthesis steps, some of which require managing solvent waste and minimizing effluent loads. Our site invested in enhanced solvent recycling and air filtration systems, well beyond what is required by local law, simply because our neighborhood is not just an industrial park, but a community with families who rely on safe air and water.

    By engaging directly with university researchers, we also seek to understand the longer-term implications of antibiotic use—not just at the end of the production chain, but through entire ecosystem models. The backdrop of emerging antimicrobial resistance demands a steady hand and a commitment to transparency. As debates heat up regarding antibiotic-free production in some markets, we advise clients honestly about withdrawal times, compatible alternatives, and the role Flumequine can still play in an integrated animal health program.

    We field growing numbers of inquiries about residue testing, not only at the point of production, but also at end-user facilities. Our analytical support team often visits feed mills and aquaculture sites to assist in implementing practical residue monitoring procedures. The trend toward more rigorous on-site testing aligns with global consumer demand for reassurance about food safety. We view these requests not as a burden, but as an important extension of what it means to stand behind a product from beginning to end.

    Continuous improvement drives our efforts. Old manufacturing processes, while robust, rarely anticipate every new challenge. By listening to customer stories—both successes and frustrations—we have changed not only how we make Flumequine, but how we package, document, and follow up after delivery. In a market where reliability, predictability, and safety are more than just slogans, every improvement counts.

    Flumequine remains one of the key compounds in our manufacturing calendar, not because of tradition, but because decades of animal healthcare professionals keep returning to it when they need results that align with tough operational realities. Our mission stays rooted in daily practice, scientific rigor, and the kind of deep listening that comes only from years of working within this hard, complicated field.