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Ferrous Gluconate Dihydrate

    • Product Name Ferrous Gluconate Dihydrate
    • Alias ferrous_gluconate_dihydrate
    • Einecs 205-711-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    251748

    Chemical Name Ferrous Gluconate Dihydrate
    Molecular Formula C12H22FeO14·2H2O
    Molecular Weight 482.18 g/mol
    Appearance grayish-green to yellowish-gray powder
    Solubility freely soluble in water
    Cas Number 6047-92-1
    Iron Content approximately 11.6%
    Storage Conditions store in a cool, dry place
    Pharmaceutical Use iron supplement for anemia treatment

    As an accredited Ferrous Gluconate Dihydrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Packed in a 25 kg fiber drum with inner polyethylene liner, clearly labeled “Ferrous Gluconate Dihydrate,” batch number, and manufacturer details.
    Shipping **Shipping Description (Ferrous Gluconate Dihydrate):** Ferrous Gluconate Dihydrate should be shipped in well-sealed, moisture-proof containers, protected from light and incompatible materials. Store and transport at ambient temperature. Ensure labeling complies with local regulations. Generally not hazardous, but avoid rough handling and contact with strong oxidizers or acids during shipment. Suitable for air, sea, or land transport.
    Storage Ferrous gluconate dihydrate should be stored in a tightly closed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, away from incompatible substances such as acids and oxidizing agents. Avoid exposure to excessive heat. Store at room temperature, and prevent contamination to maintain its stability and efficacy.
    Application of Ferrous Gluconate Dihydrate

    Applications of Ferrous Gluconate Dihydrate in Industrial Manufacturing

    As an experienced chemical raw material producer, we supply Ferrous Gluconate Dihydrate to a select range of downstream sectors where its technical profile as a mild, bioavailable iron salt underpins critical formulation and process roles. Below, we detail the practical integration of our material across principal manufacturing channels, including precise regulatory, process, and formulation references for each industrial segment.

    1. Food & Beverage Fortification

    Food and beverage manufacturers incorporate this ingredient to address iron deficiency in mass-market and specialized nutrition products. This iron source exhibits high solubility and minimal metallic taste, supporting clear-label fortification in sensitive matrices such as drinks, dairy, fruit preserves, and premixes. Process engineers adjust dosage according to regional food additive laws and targeted nutritional claims, integrating the material at liquid blending or dry premix stages to ensure homogeneous distribution without sensory impact.

    Industry compliance standards

    • Codex Alimentarius General Standard for Food Additives (GSFA CXS 192-1995)
    • EU Regulation (EC) No 1333/2008 on food additives
    • US FDA 21 CFR §184.1301 (Direct food substances affirmed as generally recognized as safe)
    • China GB 14880-2012 for the use of nutritional fortification substances

    Typical usage ratio

    • 20–120 mg elemental iron/kg in fortified premixes
    • 2–10 mg elemental iron/100 g in ready-to-drink beverages, depending on local RNI and label claims
    • Adjustment depends on product matrix, declared serving size, and regulatory maximums

    Downstream process integration

    • Added to wet or dry-blended vitamin mineral premixes before main batch processing
    • Dispersed into beverage base or syrup during aqueous stage prior to pasteurization or UHT treatment
    • Incorporated into dough or batter for bakery via premix or direct dosing after flour hydration

    Final product types

    • Infant and pediatric nutrition powders
    • Iron-fortified bottled beverages (juices, isotonic drinks, flavored milk)
    • Breakfast cereals and health bars
    • Dietetics and functional confectionery

    2. Pharmaceutical Oral Iron Formulations

    Pharmaceutical producers utilize this material in solid and liquid oral dosage forms aimed at treating and preventing iron deficiency anemia. Selection as a preferred iron salt rests on its mild gastrointestinal profile, patient compliance, and clear monograph recognition. Production chemists and formulation teams manage its introduction at the granulation, blending, or suspension compounding stages, adapting concentrations and excipient compatibility for regulatory registration and bioavailability assurance.

    Industry compliance standards

    • European Pharmacopoeia (Ph. Eur.) monograph 0962
    • United States Pharmacopeia (USP-NF) monograph
    • Good Manufacturing Practices (GMP) per ICH Q7/Q9 guidelines
    • World Health Organization (WHO) International Pharmacopoeia

    Typical usage ratio

    • Equivalent to 35–100 mg elemental iron per tablet, capsule, or sachet
    • 5–20 mg elemental iron per 5 mL dose in syrups and suspensions
    • Formulation complies with monograph-defined iron content and release specifications

    Downstream process integration

    • Blending with direct compression excipients for tablets or capsules
    • Dispersion into syrup vehicles with stabilizers and preservatives under controlled pH
    • Wet granulation with binders in multi-step solid dose production

    Final product types

    • Oral iron tablets and film-coated tablets
    • Chewable iron supplements for children and elderly
    • Liquid syrups, drops, and suspensions for pediatric and adult use
    • Powder-filled capsules and oral sachets

    3. Colorant for Table Olive Processing

    Industrial vegetable processors deploy ferrous gluconate in black olive treatment lines for pitting-resistant, color-stabilized end products. Its iron ion binds effectively with natural polyphenols under carefully controlled brining conditions, producing the characteristic uniform black hue preferred in retail and foodservice markets. Application proceeds according to regional residue limits, factoring in saline concentration, pH control, and contact time to ensure consistent, regulation-compliant results.

    Industry compliance standards

    • EU Regulation (EC) No 231/2012 (E579: Iron(II) Gluconate as food colorant)
    • Codex Alimentarius Standard for Table Olives (CXS 66-1981)
    • US FDA GRAS notice for colorants in pickled/processed foods
    • China GB 2760 as permitted food additive for olive coloration

    Typical usage ratio

    • 150–350 mg/kg brine solution
    • Exact dose benchmarks local residue allowances and intended blackening intensity
    • Adjustment based on olive variety, fruit size, and process duration

    Downstream process integration

    • Introduced during blackening bath treatment after initial alkaline de-bittering
    • Controlled mixing with brine under mechanical agitation to ensure ion saturation
    • Integrated at pre-packing or post-fermentation, followed by rinsing and preservation steps

    Final product types

    • Canned black olives for retail and catering
    • Brined and vacuum-packed sliced olives
    • Ready-to-eat olive snacks
    • Bulk-processed table olives for further food manufacturing

    4. Veterinary and Livestock Supplementation

    Producers of veterinary premixes and feed supplements use this material to formulate bioavailable iron sources for livestock, particularly swine, poultry, and companion animals. Its high absorption profile and stable blendability with macro-minerals allow precision fortification in multi-nutrient dosing programs. Processing teams add it to vitamin-mineral premix and feed supplement lines, calibrating content for breed, age, and regulatory requirements.

    Industry compliance standards

    • European Union Regulation (EC) No 1831/2003 (Additives for use in animal nutrition)
    • US FDA 21 CFR Part 582/584 (Feed additive safety and usage)
    • China Agricultural Industry Standard NY/T 370
    • Association of American Feed Control Officials (AAFCO) guidelines

    Typical usage ratio

    • 40–120 mg elemental iron/kg diet in premix or total mixed ration
    • 4–20 mg elemental iron/kg body weight daily in veterinary intervention products
    • Adaption reflects species, developmental stage, and total dietary intake

    Downstream process integration

    • Dry mixing with other trace mineral and vitamin inputs for homogeneous premix
    • Direct inclusion during pelleting or granulation of compound feed
    • Added in wet mash for specialty livestock feeds before final drying and bagging

    Final product types

    • Multi-nutrient veterinary oral powders, tablets, and pastes
    • Feed premixes for pigs, cattle, chickens, and aquaculture
    • Companion animal dietary supplements
    • Iron-fortified livestock feeds

    5. Hemodialysis and Parenteral Nutrition Solutions (Bulk API Supply)

    Medical solution compounding plants utilize this compound as a regulated API in electrolyte and parenteral nutrition blends formulated for hospital and clinical use. API-grade batches must meet strict pharmacopeial purity and heavy metal thresholds, with traceability through validated QC systems. Industrial pharmacists dissolve this iron source at solubilization tanks under aseptic conditions, dosing it as per individualized medical protocols and stability data before filtration and sterile packaging.

    Industry compliance standards

    • USP, Ph. Eur., and JP monographs for bulk pharmaceutical ingredients
    • Good Manufacturing Practices (GMP) for sterile/aseptic manufacturing (e.g., EU GMP Annex 1)
    • US FDA 21 CFR Parts 210/211 (drug substances and finished pharmaceuticals)
    • WHO prequalification for parenteral nutrition components

    Typical usage ratio

    • As per compounding formula: often 7–14 mg/L elemental iron in hemodialysis concentrates
    • 0.1–0.5 mg/mL in parenteral solution bases, depending on clinical protocol
    • Precise levels set by the hospital's clinical nutrition or nephrology department

    Downstream process integration

    • Dissolution in compounding vessel with other electrolytes and amino acids
    • Final sterile filtration and filling into unit dose vials or flexible IV bags
    • Lot traceability from input QC to hospital batch documentation

    Final product types

    • Hemodialysis iron supplementation solutions
    • IV parenteral nutrition admixtures
    • Bulk sterile solution APIs for hospital pharmacy use
    • Customized medical nutrition blends
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    Certification & Compliance
    More Introduction

    Ferrous Gluconate Dihydrate: Our Real-World Experience as a Chemical Manufacturer

    Understanding Ferrous Gluconate Dihydrate

    Over years of producing mineral salts, we've found that Ferrous Gluconate Dihydrate continues to be one of the most dependable iron sources across different industries. This compound stands out for more than just its role as an iron supplement. We have witnessed its performance day in, day out, where shelf stability, controlled iron release, and consistent reactivity make direct contributions to finished product quality. The typical model we produce aligns with the empirical formula C12H22FeO14·2H2O. Ferrous Gluconate Dihydrate appears in light yellow to greenish-gray powder form, meeting commonly accepted quality standards for iron content and purity.

    Why Direct Manufacturing Matters

    As a manufacturer, we pay attention to the small things that buyers might miss. Production variables affect iron stability and solubility. Daily batch checks, on-site raw material quality control, and consistent drying protocols make the real difference that shows up in your lab tests. We work with food, nutraceutical, and pharmaceutical partners facing tough regulatory scrutiny. Any deviation gets caught before a product leaves our factory door. By producing our own Ferrous Gluconate Dihydrate, without relying on bulk traders or blending brokers, we avoid unpredictable results. End users get the full-strength, traceable product that regulatory agencies expect.

    Model and Specifications: What Sets Us Apart

    Our standard model of Ferrous Gluconate Dihydrate falls within established pharmacopeia guidelines, supporting both food and pharmaceutical applications. We offer iron assay levels meeting domestic and export requirements. Moisture, heavy metals, and total ash remain tightly monitored, and we never allow product to ship out of spec. Customers typically ask about color, solubility, and odor, since these characteristics affect consumer perception. Our batches produce a consistently mild flavor profile with no metallic aftertaste when used in food fortification. We maintain a carefully controlled water activity bracket to prevent clumping, which logistics teams appreciate.

    How Experience Shows in Our Product

    Producing Ferrous Gluconate Dihydrate is more than following checklists. We've learned that storage temperature, pH of solutions, and even minor process changes shift the oxidation state of iron. Each production run relies on robust analytical checks. We stick with food-grade stainless steel and lined reaction vessels to limit contamination risk. Filtration methods, validated for iron retention and particle-size distribution, keep slurry under control. Over the years, we have strengthened our microbial control protocols because food and supplement markets demand absolute safety. Success means that a bakery, beverage company, or tablet producer can take a shipment and find no surprises—only the expected, reliable iron supplement their process demands.

    Differences from Other Iron Salts

    Having manufactured both Ferrous Gluconate Dihydrate and alternatives such as Ferrous Sulfate, Ferrous Fumarate, and Ferric Ammonium Citrate, we see where this product outperforms or fills unique needs. Ferrous Gluconate Dihydrate’s gentle reactivity and higher palatability make it the material of choice in products where taste and mouthfeel matter. As an iron fortifier in canned foods like black olives, it preserves the desired dark color better than other salts. In beverages and liquid supplements, it provides iron without causing haze or sediment, which is a constant headache with some crystalline iron sources. Where iron discoloration or off-flavors are at stake, formulators trust this material over harsher salts.

    Major Uses Across Industries

    From the early days, nutritionists have recognized the safety and effectiveness of Ferrous Gluconate Dihydrate for food and supplement fortification. In our experience, food manufacturers appreciate the way it dissolves smoothly into liquid premixes, especially in drinks or processed foods where even dispersion and minimal impact on flavor take top priority. Tablet producers rely on its mild profile for pleasant-tasting multivitamins. Often, companies working with infants, children, and pregnant women request detailed impurity testing reports, and the samples regularly exceed national and global thresholds for safety.

    On the industrial side, several process chemists have switched to Ferrous Gluconate Dihydrate for color preservation—especially in canned vegetables and olives. They need reliable, shelf-stable iron, and any shift in batch quality shows up as color drift in the finished product. Consistent solubility allows for quick reaction and cleanup, sparing excess downstream filtering. Product developers pull us into new projects when other iron forms irritate taste panels or cause technical frustration farther down the line.

    Food Fortification and Supplements: Putting Iron Where It Matters

    Iron deficiency causes untold health burdens, so getting the chemistry and process right is critical. We have seen firsthand the difference that tightly manufactured iron salts make in solving anemia challenges in public health. When schools or government entities fortify dairy, grains, or infant formulas, they come to us for batch certificates and traceability data. Many of our clients want product that not only complies with country standards but also meets tough private certification schemes. Years of serving these customers have prompted us to develop internal test protocols with lower impurity allowance than the broadest regional mandates.

    Tablets and capsules—especially where brands market toward children, prenatal care, or sports nutrition—often require masked flavor or gentle iron release. Feedback from contract supplement packagers keeps us informed about any issues with excipient compatibility or tablet compression. We regularly trouble-shoot alongside our customers, and this collaboration shapes both our product and process improvements. Even in effervescent supplement blends, our batches keep reactivity under control, avoiding oxidation or destabilization of other actives.

    Production Process: Consistency Drives Confidence

    Routine is key in our plant. Each batch of Ferrous Gluconate Dihydrate begins with pharmaceutical-grade gluconic acid and high-purity iron salts, tracked in our manufacturing software before blending. Real-time iron titration and solution clarity checks guide reaction parameters. Through hands-on oversight, our plant supervisors adjust blending rates, monitor temperature, and validate filtrate to ensure no iron losses or unwanted byproducts enter the final cake.

    After drying and granulation, we use laser particle-size analysis to guarantee proper powder flow for food and supplement applications. Lot samples move to both in-house and third-party labs for elemental iron, impurity metals (including arsenic, lead, and cadmium), and pathogen testing. Only clear-compliance powder reaches the bagging room. Batch retention and tight traceability records ensure we address any inquiries from auditors, clients, or regulators without delay.

    Safety and Regulatory Compliance: A Daily Commitment

    Every kilogram that leaves our plant must hold up to customer and regulator scrutiny. We have invested in employee training, HACCP system documentation, and GMP audits. Regulatory changes across borders—whether new labeling laws or contaminant limits—translate into updated test panels and more frequent quality verification. In our own experience, regional demand varies, but safety never takes a back seat. This vigilance means our Ferrous Gluconate Dihydrate is trusted by well-known food and supplement brands in densely regulated markets.

    Third-party audits sometimes bring surprises. We welcome these, since they push us to prove our cleaning regimes, foreign material controls, and lot traceability. Customer visits often turn into open-book sessions, with teams reviewing test records, walking floor lines, and even spot checking environmental monitoring logs. These protocols reinforce the importance of built-in safety in everything we ship.

    How Consistency and Service Retain Customers

    Partnerships last because we back up our promises with measurable performance. Long-running customers return because they recognize that some risks get resolved only by going straight to source. We have worked with product formulators who once blamed their downstream clumping or color shifts on other ingredients. Through open batch testing and process adjustments, they found that the difference actually lay in the choice of ferrous salt and manufacturing method. In those situations, our technical service teams step in to diagnose problems using real samples—not just theoretical advice—helping partners cut waste, improve flow rates, or boost finished product shelf life.

    Even after delivery, our role continues. If a client launches a new beverage, fortified snack, or supplement, we share insights on pH, storage, and interaction with stabilizers that we've collected after years supporting similar launches. Seasonal humidity, container handling, and new blending lines all influence performance, and our feedback helps prevent issues before they reach consumers. This hands-on approach produces a strong sense of trust in our material's reliability.

    Responding to the Toughest Troubles

    Real-world use presents challenges every lab test can't predict. Years ago, a customer faced spotty browning in canned olives—traceable back to inconsistent ferrous salt suppliers. Our teams visited the facility, reviewed their blending, and traced root causes to quality variations in their raw Ferrous Gluconate Dihydrate. After a process redesign and steady shipments from our plant, the client recovered market share and had fewer product recalls. Similar stories repeat in food and supplement manufacturing: taste drift, color loss, and delayed iron release often stem from batch inconsistency or overlooked process variables.

    We view each line halt, complaint, or rejected lot as a signal to reexamine old habits. Solutions usually require experience—tweaking filtration flow, reviewing drying temperature profiles, or retesting for minute contaminants. Over time, this commitment produces a steady, predictable product line, keeping our downstream partners competitive and confident.

    Comparing Ferrous Gluconate Dihydrate with Other Iron Salts

    Not all iron salts solve the same problems. Some, like Ferrous Sulfate, have higher elemental iron content per weight and come at a lower material cost. Inexpensive, straightforward, but gums up processing lines with sulfate odors or leads to complaints about taste and after-effects when used in oral supplements. Ferrous Fumarate offers concentrated dosing but suffers the same metallic notes and can form gritty suspensions in food. Ferric Ammonium Citrate works for beverage stabilization but often falls short in less acidic or non-aqueous systems.

    In our daily experience, Ferrous Gluconate Dihydrate stays stable across a broader range of food formulations. Even at higher iron loads, it evades metallic taste or chemical aftertaste—an advantage for producers of juice, cereal, or infant nutrition. As a result, brands focused on gentle flavor, easy digestion, and good customer feedback tend to standardize on this iron source. Production lines run smoother, process water stays clear, and analytical tests return in spec batch after batch.

    Looking Forward: Ongoing Improvements in Our Manufacturing

    Demands for traceability and sustainability push us to constantly upgrade how we produce Ferrous Gluconate Dihydrate. Suppliers want to know their raw materials come from clean, verified sources. We have built more rigorous supplier audits, improved closed-system analytics, and installed better filtration for environmental protection. Our wastewater treatment system receives routine investment, ensuring we operate with respect for both product quality and our surroundings.

    On the technical side, our research teams invest time in refining granularity, improving powder storage life, and deepening our understanding of interactions within finished food and supplements. We meet regularly with downstream partners, learning exactly how product behaves in real processing conditions—heat, pressure, agitation, prolonged storage. What we learn gets fed back into process improvements and inspires new analytical methods to set tighter batch targets.

    Global Application and Export Realities

    Serving customers around the world means every shipment of Ferrous Gluconate Dihydrate has to meet or exceed different regulatory and consumer expectations. Logistics partners monitor temperature and humidity control on the way to distant destinations. Regulatory teams verify that each batch carries the right certifications and documentation. Our experience with international shipments has formed strict routines—no cutting corners, no rushing late orders, and transparent communication with clients on every step from production to delivery.

    This level of care assures importers and overseas brands that they aren't taking unnecessary risk by sourcing direct from us. Where clients require adherence to food safety schemes such as FSSC or ISO standards, we supply evidence and allow for onsite or virtual inspections. Every region brings its own quirks, from paperwork to labeling, and we keep a close dialogue with buyers so they can avoid costly setbacks.

    Our Long-Term View

    Ferrous Gluconate Dihydrate sits among the most crucial materials we offer—appreciated by processors, supplement makers, and food fortification programs for its reliability, neutral flavor, and proven safety profile. As consumer trends shift toward cleaner labeling, traceable sourcing, and science-backed fortification, we keep investing in skills, clean facilities, and analytical controls.

    For us, producing Ferrous Gluconate Dihydrate isn't about batch numbers or volume records. It represents years of learning from the people and processes that count on this material to solve real nutritional, technical, and production challenges. Our daily focus stays fixed on consistency and partnership, backing up every shipment with the experience and attention to detail that come only from hands-on manufacturing. This way, end users know they are getting a product that performs every time, with full transparency and accountability from source to finished application.