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Ethyl Tetrahydro-2-Furoate

    • Product Name Ethyl Tetrahydro-2-Furoate
    • Alias 2-Furancarboxylic acid, tetrahydro-, ethyl ester
    • Einecs EINECS 220-817-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    441357

    Cas Number 4368-60-1
    Molecular Formula C7H12O3
    Molar Mass 144.17 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 194-196°C
    Density 1.06 g/cm³ (at 20°C)
    Refractive Index 1.439-1.441
    Flash Point 84°C
    Solubility In Water Slightly soluble
    Odor Mild, fruity

    As an accredited Ethyl Tetrahydro-2-Furoate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500 ml of Ethyl Tetrahydro-2-Furoate is supplied in a sealed amber glass bottle with a tamper-evident screw cap.
    Shipping Ethyl Tetrahydro-2-Furoate is shipped in tightly sealed containers, protected from light, moisture, and heat. It should be handled in accordance with hazardous chemical regulations, including appropriate labeling and documentation. Ensure upright, stable transport and avoid incompatible substances. Follow all local, national, and international transport guidelines for safe delivery.
    Storage Ethyl Tetrahydro-2-Furoate should be stored in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames. Keep the container tightly closed and protected from direct sunlight. Store separately from oxidizing agents and strong acids or bases. Use corrosion-resistant containers and ensure proper chemical labeling to prevent accidental misuse or spillage.
    Application of Ethyl Tetrahydro-2-Furoate

    Applications of Ethyl Tetrahydro-2-Furoate in Industrial Manufacturing

    As an experienced manufacturer, we deliver Ethyl Tetrahydro-2-Furoate with consistent quality to enable reliable production processes across specialized industrial segments. The following application scenarios illustrate where this product directly supports manufacturing operations, regulatory compliance, and final product performance in established downstream value chains.

    1. Flavor and Fragrance Compounding

    Flavor and fragrance houses rely on Ethyl Tetrahydro-2-Furoate as a key ingredient in the formulation of high-impact fruity and caramel notes for food and beverage flavoring, as well as fine fragrances. Its organoleptic profile provides characteristic warmth and roundness favored in apple, melon, honey, and sweet brown-type accords, and its high purity ensures batch-to-batch performance required for regulatory and sensory quality. Manufacturers incorporate it delicately to avoid flavoring imbalances, with application varying by region and finished product form.

    Industry compliance standards

    • FAO/WHO Codex Alimentarius Food Additive Standards
    • US FDA CFR 21 §172.515 (Synthetic flavoring substances and adjuvants)
    • European Regulation (EC) No 1334/2008 (Flavorings and certain food ingredients with flavoring properties)
    • IFRA Standards for Fragrance Substances

    Typical usage ratio

    • 0.01–0.1% w/w in compound flavors and fine fragrances; level tailored according to desired intensity and regulatory maximum limits per end market (e.g., maximum inclusion level as per EU flavoring regulations)

    Downstream process integration

    • Dosed at the flavor/fragrance compounding stage after main solvent blending, followed by pre-mixing with other esters and aldehydes prior to top-note adjustment and QC organoleptic validation

    Final product types

    • Beverage and confectionery flavors
    • Ready-to-use food ingredient blends
    • High-end fine fragrances
    • Toiletry and personal care fragrances

    2. Pharmaceutical Synthesis Intermediate

    API manufacturers use Ethyl Tetrahydro-2-Furoate as a building block in the synthesis of advanced furan- and lactone-based intermediates, which subsequently enter production routes for select active pharmaceutical ingredients. Its high purity and low impurity profile help limit byproduct formation, supporting cGMP-compliant manufacturing pathways for small molecule APIs. The molecule’s reactivity in esterification and hydrogenation steps is especially valued in multi-step pharmaceutical chemistry under tightly controlled process conditions.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • EU GMP Directive 2003/94/EC
    • US FDA 21 CFR Parts 210/211 (cGMP for finished pharmaceuticals)
    • USP <795> for pharmaceutical compounding (when applicable)

    Typical usage ratio

    • Employed in molar equivalent amounts required by route of synthesis; typical range: 0.5–2 equivalents per API unit depending on structure; stoichiometry defined by process route and yield optimization studies

    Downstream process integration

    • Charged in initial synthesis reactors for heterocyclic ring formation or intermediate esterification; followed by purification and onward conversion to target intermediates; integrated into batch records and validated cleaning protocols

    Final product types

    • API intermediates for furanone and lactone-containing drug molecules
    • Final APIs for use in regulated human and veterinary pharmaceuticals
    • Bulk pharmaceutical chemicals for further custom synthesis

    3. High-Performance Polymer Feedstock

    Producers of high-performance engineering plastics and specialty polyesters utilize Ethyl Tetrahydro-2-Furoate as a sustainable monomer precursor. Its unique furan-based structure allows for integration into polyesterification processes, contributing improved flexibility, barrier properties, and partial renewability compared to petrochemical-based monomers. This raw material is especially relevant in the manufacture of bio-derived packaging films and certain copolymer systems for niche engineering plastics.

    Industry compliance standards

    • US FDA 21 CFR §177.1630 (Polyethylene phthalate polymers for food contact)
    • REACH Regulation (EC) No. 1907/2006 for polymer registration and SVHC compliance
    • EN 1186 & EN 13130 for overall and specific migration in food-contact plastics (EU)
    • ISO 9001-certified quality management systems for polymer manufacturing

    Typical usage ratio

    • 1–5 mol% as partial co-monomer substitution in polyester and copolyester synthesis; precise level determined by polymer performance targets and melt processing capabilities

    Downstream process integration

    • Directly introduced in melt-phase transesterification or polycondensation reactors; reacts alongside dimethyl terephthalate or other diesters and glycols; monitored for conversion efficiency and incorporated into resin QC fingerprint analysis

    Final product types

    • Flexible food-grade packaging films
    • Specialty bio-polyesters and copolyesters
    • Barrier materials for PET bottle and multilayer structures
    • Technical plastics for electrical and automotive components

    4. Agrochemical Formulation Intermediate

    Agrochemical producers utilize Ethyl Tetrahydro-2-Furoate in the synthesis of selected pesticide, fungicide, and herbicide intermediates. Its functional ester group enables targeted molecular transformations necessary for the development of high-activity crop protection agents. Regulatory traceability and analytical purity are tightly managed within the context of plant protection product development and large-scale technical grade synthesis.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • EU Regulation (EC) No 1107/2009 (Authorization of plant protection products)
    • US EPA PRN 98-10 (Data requirements for chemical intermediates in pesticide synthesis)
    • ISO 17025-accredited analytical methods for QC

    Typical usage ratio

    • 0.2–1.0 molar equivalents relative to active ingredient precursor, adjusted by the synthetic sequence; selection guided by yield and downstream purification needs

    Downstream process integration

    • Dosed at the controlled intermediate formation stage in multi-step synthesis; involved in key esterification or reduction reactions before isolation and further conversion to technical grade agrochemicals

    Final product types

    • Pesticide active ingredient intermediates
    • Formulated technical concentrates for crop protection
    • Specialty fungicides and herbicides

    5. Specialty Solvent for Analytical and Fine Chemical Use

    Fine chemical laboratories and analytical standards producers employ Ethyl Tetrahydro-2-Furoate as a specialty solvent or sample diluent due to its low volatility, chemical stability, and minimal background interference in chromatographic applications. Strict attention to trace impurity profiles and batch consistency underpins its utility as a carrier in the preparation of calibration standards and certified reference materials for regulated and research environments.

    Industry compliance standards

    • ISO Guide 34 / ISO 17034 (General requirements for the competence of reference material producers)
    • USP <621> (Chromatography)
    • GLP (Good Laboratory Practice) compliance for certified reference material preparation
    • ISO/IEC 17025 for laboratory quality systems

    Typical usage ratio

    • Used as received (100%) in reference standard preparations; as sample diluent, 1–10% v/v relative to analyte concentration, depending on method and instrument sensitivity

    Downstream process integration

    • Weighing and dispensing under cleanroom or controlled laboratory conditions; used during sample preparation and as a mobile phase additive or matrix in chromatographic and spectrometric analyses

    Final product types

    • Certified analytical reference materials (CRM)
    • Laboratory calibration standards
    • Fine chemical mixtures for method validation
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    Certification & Compliance
    More Introduction

    Ethyl Tetrahydro-2-Furoate: Our Approach from the Production Line

    Hands-On Manufacturing: Why Consistency Matters

    In our facility, days start early and end with a strict review of the last drum. With Ethyl Tetrahydro-2-Furoate, every batch represents more than just chemical synthesis—the final product shows the value of human precision, clean handling, and years of process improvement. We keep a close eye on crystallization, distillation, and purity benchmarks for every shipment. If a small bit of water or side product appears where it does not belong, we search for root causes immediately, whether that means recalibrating a condenser or tightening down process steps.

    This approach keeps our product where it should be: pale, clear, and stable from the first fill to the last drop. Our laboratory does not rest with automated readouts; skilled technicians cross-check instrument readings by smell, touch, and focused eyes on every change. Subtle differences, such as shifts in color or aroma, can mean someone upstream missed a filter change or underestimated the pressure during reaction. By sticking with hands-on checks at every stage, we make sure Ethyl Tetrahydro-2-Furoate arrives at customer sites ready for immediate use, without surprises in solubility, odor, or color.

    Product Profile: Our Ethyl Tetrahydro-2-Furoate

    We have honed the steps needed to produce Ethyl Tetrahydro-2-Furoate at a high purity meeting the needs of downstream customers in flavors, industrial fragrances, and specialty solvent production. Our batches carry the model ET2F-190, which stands for the specific temperature, pressure, and hydrogenation cycle we perfected over many years. We use locally sourced feedstocks with traceable origins to maintain tight control over raw material streams. In our team’s experience, this approach brings better batch-to-batch reproducibility than generic sources.

    Small details make large differences. Our standard purity for Ethyl Tetrahydro-2-Furoate sits above 99.5%, with moisture under 0.1% and a sharply limited furan odor profile. Each lot comes off the line clear and free-flowing, checked not just by gas chromatography but by senior team members who have seen both good and bad years. Physical characteristics—including melting point, refractive index, and specific gravity—show much tighter tolerance bands than what we have seen in market averages.

    How Ethyl Tetrahydro-2-Furoate Stands Apart

    Comparison against traditional esters like ethyl 2-furoate or methyl tetrahydrofuran-3-carboxylate reveals a key difference: Ethyl Tetrahydro-2-Furoate retains the core benefits of the furan ring while minimizing reactivity during downstream blending. Because we minimize by-products from the hydrogenation step, the resulting ester resists darkening under light or mild heat, and maintains stability when mixed with aldehydes or acids in fragrance bases. Many customers tried switching from older furan esters because they noticed breakdown products that gummed up lines or changed flavors with time; we see Ethyl Tetrahydro-2-Furoate as a solution based on direct customer feedback.

    Another technical difference becomes apparent for those working in solvents and coatings. Our Ethyl Tetrahydro-2-Furoate, once introduced into formulations, shows lower evaporation losses than less saturated furyl esters. Formulators looking for balance between volatility and lingering aroma have confirmed that. This gives end products a smoother performance during application and keeps final scents true, especially in humid environments where ingredient interactions can swing outcome by more than anticipated.

    Production Insights from an Operator’s Perspective

    Every operator here knows the pressure of a tight production window and the vigilance needed to maintain a reliable product. Most industrial literature covers the formal chemistry, but less often do people discuss the practical issues—like filter clogging or temperature runaways—faced in the plant. Our shop-floor adjustments, such as keeping jacketed reactor surfaces clean and rotating catalyst charges timely, matter more than any single database number. This not only guards the product quality but also builds trust up and down the supply chain.

    In seasons when humidity spikes, or raw feedstock shows a minute impurity, we have learned to adapt batch times and hydrogen flow rates quickly. These real-world factors shape whether the final ester ends up meeting our standards or serves only as intermediate material. Colleagues sometimes visit our line and express surprise at our strict limits on acid value and peroxide content; we do this not for show, but because it eliminates headaches months later. The more attention given at synthesis and refinement, the lower the odds of bad surprises during customer use.

    Minimizing Hazards and Waste in Real Manufacturing

    From the start, we targeted low-residue hydrogenation methods to bring the risk of hazardous byproducts down. Traditional processes often leave traces of unsaturated compounds or furanic residues that degrade downstream machinery or demand extra purification. Our workflow keeps closed-system containment during reaction and cooling, which protects both the workers and the finished chemical from air and moisture. By recovering nearly all solvents and recycling washing solutions through our in-house system, we keep production lean and environmentally responsible.

    We also channel feedback from our customer technical teams. Years ago, a major user raised concerns about batch-to-batch color drift. With their input, we rebuilt our polish filtration and improved post-reaction dry-down, sparing employees from extra manual scrubbing and end-users from lengthy clarification stages. These close exchanges have helped us meet rising expectations around product sustainability and lot documentation, which can make a difference if a brand faces an audit.

    End Uses: Guidance from Years in the Field

    Ethyl Tetrahydro-2-Furoate does not sit idle on shelves. Our clients, ranging from specialty aroma houses to chemical blenders, take advantage of its subtle vanilla-bread note and mild, non-aggressive profile for food flavors and fragrance development. Over time, formulators have migrated from more reactive furans, preferring the stability and neutral sweetness present in our material. In the bakery and dairy flavor sectors, the ester profile supports cream and butter notes without the harshness of some higher furanics.

    In non-food sectors, such as textile auxiliaries and cleaning aides, Ethyl Tetrahydro-2-Furoate has gained ground against standard esters, largely due to its low odor retention and better wash-out rates. Regulatory reviews confirm its benign breakdown in water processing plants—one feature our environmental compliance manager has been adamant to protect. Paint and coating developers appreciate its smooth-tack finish and improved adhesion when added to acrylic and latex formulations. These aren’t just claims from advertisements; every characteristic mentioned here comes from direct application and customer QA feedback.

    Responding to Market Demands, Not Market Myths

    Outside marketing circles, real feedback drives our process. Some sources exaggerate rare use-cases or promise performance outside the bounds of chemistry. We filter these reports by testing each claim in our technical center before even mentioning it to technical buyers. If an application—such as reactive ink additives—looks promising, our team runs repeated tests under simulated plant conditions before presenting a white paper or updated guidance. This approach has saved both us and our clients headaches with failed pilot batches or unsalable product.

    The lessons learned through real manufacturing experience shape product conversations. For example, one time a partner’s fragrance blend started clouding. We backtracked, sent sample batches for side-by-side testing, and pinpointed a trace impurity from an upstream alcohol—solved with a minor process tweak at our facility. These stories show the difference between pushing a reagent based on spec sheets and building a supply partnership rooted in technical transparency.

    Why Reliable Supply Makes a Difference

    Unplanned shortages and delays cause real pain for production planners and end users. We make room in our annual schedule to carry buffer stock and pre-approved alternate raw suppliers, reducing risks from logistics hiccups or feedstock quality changes. This extra margin costs us in working capital, but experience has shown the value many times over. During major storms, when road and sea routes get disrupted, our warehouse and finished goods silo have filled critical gaps for contract customers.

    In global supply chains, trust is fragile. Our customers in the EU, Asia, and the Americas expect shipment schedules to match what’s on the contract—not best-case estimates. We don’t outsource our core production or cut corners on cleaning and line prep, because we have seen how slight mistakes get magnified at scale. Our own distribution team handles every drum, churn, and shipment, so that we can identify where a problem started if anything does go wrong.

    Documentation and Traceability Practices

    With increasing international compliance, we maintain a thorough record from lot inception to final drum. Each batch runs with a traceable audit trail, tying each raw batch, catalyst lot, and downstream filtration step. Electronic records run parallel with physical barcodes throughout our processing facility. If a customer audit or regulatory review needs proof of compliance, we are ready to supply the required documentation.

    We also store retains of each shipment, enabling retrospective analysis if anything changes during the shelf life at the customer’s site. Our standard offering includes COA data and, for many industries, supplementary documentation on extractables, residual solvents, and food-grade status. Unlike one-size-fits-all datasheets, we actively update our records based on customer-unique requirements and new analytical findings.

    Feedback Drives Improvement

    Change does not come from theory alone. The most valuable development comes from open lines with technical users who find a challenge in their process. We have adjusted our distillation sequence after one customer in beverage flavors picked up a faint background note that did not fit their brand. Another paint manufacturer requested drought-resistant packaging after seeing repeated swelling or minor drips when stored under fluctuating temperatures. We respond not just by offering an apology, but by building new testing protocols and, where possible, adjusting core process equipment.

    Beyond the lab floor, we promote technician training, so every employee understands the difference a five-minute pressure drop or two-degree deviation can make. Our improvement cycle relies on operator input, not outside consultants pushing generalized process models.

    Continued Vigilance in Production and Use

    Every chemical has unique needs regarding storage and handling. Ethyl Tetrahydro-2-Furoate keeps a low hazard profile, but our team keeps a sharp eye for cross-contamination, temperature creep, or early signs of bottle discoloration in long-term storage. We have built safeguards such as nitrogen purges in the tank farm and quick-access extra filtering units. Tanks go through regular detergent and steam cycles, even if process controls find no faults.

    We discuss with logistics partners how to keep the product from prolonged heat exposure in transit, especially during summer months. Nothing replaces close communication with end-users when delivery times, storage conditions, or local regulations start to change. If a drum shows up at the customer’s door with cloudiness or off-odor, our door stays open to quick evaluation and remedy. That’s how confidence in each batch stays strong and real-world use remains seamless.

    Looking Forward: Meeting Tomorrow’s Standards Today

    New regulations, customer segments, and application fields keep raising the bar. We run pilot trials in emerging applications and continue adjusting to new analytical detection limits, especially as food and fragrance sector guidelines shift. Our research team rejects shortcuts; we are slow to add new synthetic steps or raw materials until they are vetted by long-term test runs and team review. Internal standards for our Ethyl Tetrahydro-2-Furoate often stay higher than current regulatory lines, both because it keeps us ahead of the curve and because it protects our customers from unnecessary production stops.

    From listening to user feedback to refining our in-house methods, we remain committed to building value for technical partners—not just chemical sales. Decades on the shop floor and years adapting to new requirements have taught us that the real measure of a product lies in what it delivers in practice, not just what a spec sheet promises.