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HS Code |
345240 |
| Productname | Ethyl 4-Ethoxybenzoate |
| Casnumber | 619-78-7 |
| Molecularformula | C11H14O3 |
| Molecularweight | 194.23 g/mol |
| Appearance | White to off-white crystalline powder |
| Meltingpoint | 61-63°C |
| Boilingpoint | 298-300°C |
| Density | 1.08 g/cm3 |
| Solubility | Slightly soluble in water, soluble in organic solvents such as ethanol and ether |
| Purity | Typically ≥98% |
| Structuralformula | C6H4(CO2C2H5)(OC2H5) (para-ethoxy group) |
| Iupacname | Ethyl 4-ethoxybenzoate |
As an accredited Ethyl 4-Etoxybenzoate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Ethyl 4-Ethoxybenzoate is supplied in a 250g amber glass bottle with a tight-sealed cap and clear hazard labeling. |
| Shipping | Ethyl 4-Ethoxybenzoate is shipped in tightly sealed containers, protected from moisture and light. It should be handled as a stable organic compound, with recommended storage at room temperature in a well-ventilated area. Transportation complies with applicable regulations to prevent leaks or spills and ensures safety during transit. |
| Storage | Ethyl 4-ethoxybenzoate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as oxidizing agents. Protect from moisture, direct sunlight, and excessive heat. Ensure proper labeling and keep away from food and drink. Follow local regulations and good laboratory practices for safe storage. |
Applications of Ethyl 4-Ethoxybenzoate in Industrial ManufacturingEthyl 4-ethoxybenzoate serves as a specialty intermediate across tightly regulated processing chains in the chemical, pharmaceutical, and cosmetic industries. As a direct manufacturer, we observe how precise handling, formulation ratios, and compliance demands drive its industrial value. The following sections detail actual downstream application scenarios, addressing regulatory adherence, integration steps, and finished product pathways. 1. UV Filter Intermediate for Personal Care Sunscreen FormulationIn the personal care sector, downstream manufacturers use ethyl 4-ethoxybenzoate as an intermediate for synthesizing FDA-listed sunscreen actives, notably octocrylene and similar benzophenone derivatives. The compound enters multi-step synthesis trains where strict impurity profiles, low residual solvent content, and controlled reaction times are validated under cGMP. Production lines prioritize monitoring of raw material assay and traceability to meet the quality protocols of EU Cosmetic Regulation. Finished sunscreen products undergo photostability and skin irritation testing before release. Industry compliance standards
Typical usage ratio
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2. Pharmaceutical Intermediate for Local Anesthetic API SynthesisThe pharmaceutical industry utilizes ethyl 4-ethoxybenzoate for the synthesis of p-aminobenzoic acid esters, a core structural component in several local anesthetic agents like benzocaine and procaine hydrochloride. Process controls ensure batch consistency to USP and EP standards, maintaining impurity spectra required for successful downstream API registration. Documentation for traceability and residual solvent monitoring forms part of annual GMP audits. The compound is handled under dedicated area segregation to prevent cross-contamination in pharma intermediates production. Industry compliance standards
Typical usage ratio
Downstream process integration
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3. Plastic Additive Intermediate in Advanced Polymer EngineeringDownstream engineering plastics manufacturers rely on ethyl 4-ethoxybenzoate as a monomer modifier or functional group carrier for liquid crystal polymers (LCPs) and specialty polyesters. The compound provides rigidity and adjustable melting characteristics. Processing lines emphasize raw material pre-heating, moisture control, and compatibility checks with other diacid/diol constituents. Quality assurance teams monitor polymer melt flow, molecular weight distribution, and contamination risk, all of which link directly to performance specifications in automotive, electronics, and high-precision film sectors. Industry compliance standards
Typical usage ratio
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4. Flavor and Fragrance Ester Precursor in Food & Beverage Additive SynthesisWithin the flavor and fragrance sector, ethyl 4-ethoxybenzoate is processed as an intermediate for structure-specific esters used in food-safe aromatic compounds. Downstream blending operations enforce compliance to FEMA GRAS and IFRA standards, verifying residual solvents and byproduct limits. Plants incorporate batch tracking and allergen risk assessments per food safety HACCP plans. Finished flavor esters undergo organoleptic panel evaluation and stability storage trials before entering global distribution. Industry compliance standards
Typical usage ratio
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5. Specialty Coating and Paint Additive SynthesisAdvanced coatings and ink producers incorporate ethyl 4-ethoxybenzoate as a molecular spacer in high-transparency, UV-resistant resins for industrial and automotive coatings. Its integration occurs under tightly regulated stoichiometry, emphasizing solvent compatibility and absence of impurities as per global environmental health laws. Continuous process monitoring ensures adherence to VOC targets and end-use weathering performance. End products face accelerated aging and adhesion testing, critical for global OEM supply chains. Industry compliance standards
Typical usage ratio
Downstream process integration
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Working in the field of chemical production brings a certain pride when introducing a molecule like Ethyl 4-Ethoxybenzoate. Every batch we produce reflects decades of refining, choosing the purest raw materials, and listening to what laboratories and industrial users say about what sets an effective intermediate apart. Ethyl 4-Ethoxybenzoate stands out because its performance in real environments offers more than just textbook numbers—it shows consistency where others might yield unpredictable results.
The product we make derives from benzoic acid chemistry, but the addition of an ethoxy group at the para position and an ethyl ester bond brings new capabilities. Our typical grade meets a strict minimum purity of 99.5% by GC, and we monitor common impurities that sometimes sneak past in less vigilant plants, such as related acids, unreacted alcohols, and trace water. Each step, from weighing raw aromatic acids to final distillation, happens under a closed system with rigorous in-process checks. Batch records and reference samples back up every certificate released, which gives our partners the confidence that tomorrow’s delivery matches yesterday’s promise.
We deliver this compound as a colorless to pale yellow liquid, clear without haze, and without perceptible odor—a point that matters to many who work in tightly controlled flavor, fragrance, or pharmaceutical suites. Every shipment leaves in clean, tested drums or custom IBCs, fitted with tamper-proof seals and batch coding, and we log every detail back into our system for full traceability.
Chemists ask us about the differences between straight ethyl benzoate, methyl paraben esters, and Ethyl 4-Ethoxybenzoate. While all these compounds share aromatic roots, the ethoxy substitution in our product changes solubility and enhances reactivity with certain substrates. In formulation work, subtle differences in volatility and solvency power affect process choices and end use. Where alternatives might cause cloudiness or incompatibility in a blend, our product remains clear, without separating over time.
One repeating story we hear involves customers switching from unmodified ethyl benzoate and finding that Ethyl 4-Ethoxybenzoate enables faster dissolution and reduced residue in their reactors. Over scale-up, this advantage transforms into precious hours saved, less wear on pumps and mixers, and fewer headaches about unreacted sludges fouling lines. It also enables more freedom choosing co-solvents, since the molecule’s extra ethoxy leg increases miscibility with both polar and nonpolar components in a way plain esters can't match.
Ethyl 4-Ethoxybenzoate finds use wherever precise aromatic esters are valued, especially in pharmaceutical intermediates, specialty resins, custom flavors, and advanced cosmetic systems. Transesterification, condensation, and alkylation reactions all benefit from the molecule’s balance between reactivity and mildness. Formulators who once dealt with variability or off-notes from less pure sources often report steady downstream quality after switching to our product.
In pharmaceutical research, its predictable ester hydrolysis, clean conversion rates, and gentle profile help develop prodrugs and masked biosynthetic intermediates. Drug synthesis often demands both speed and reproducibility, and here, our product’s clear chromatographic background and lack of residual byproducts matter. On the other hand, those developing flavor compounds find value in the mild aromatic boost this ester brings, without the overpowering incense notes other benzoates might leave behind.
Personal care manufacturers look for molecules that won’t cause color drift or interact negatively with sensitive actives. We’ve worked closely with formulators facing challenges with earlier benzoate derivatives, where extraction into oil or alcohol phases proved inconsistent. Reports of haze, loss of clarity over storage, and fading scent profiles led several labs to opt for our consistently transparent variety. The improvement stood out after stability tests: color and clarity pass industry thresholds, and complex emulsions keep their uniform appearance longer.
Compared to options on the market, Ethyl 4-Ethoxybenzoate asks more from a manufacturer. Precise temperature control, inert atmosphere management, and advanced filtration steps separate high-value production runs from basic commodity output. Many producers use open-air batch processes, with batch variability appearing as haze or off-odor when the product leaves the factory. Our method employs continuous monitoring, stainless reactors adapted for aromatic ester synthesis, and specialty-grade solvents to keep fineness from the earliest reaction through to the final drum.
Some customers have pointed out that while lesser grades sometimes underperform, the real toll shows only after months in storage. Yellowing, separating, or uncertain fragrance notes translate into product recalls, extra purification, and lost time. By following tighter process controls and never shortening our purification sequence for speed or cost, we watch over each lot through both accelerated aging and real-time storage before release. At our scale, small process misses can affect metric tons—so diligence in the small things saves both trouble and reputation.
A manufacturer’s experience does not stop at the plant gate. Over the years, partners in diverse industries—drug companies, flavor houses, polymer labs, and research institutions—have shared their struggles with low-solubility additives, harsh odor, or premature breakdown products. Generic aromatic esters can behave unpredictably in new formulations, causing inconsistent performance in downstream products. Replacing problem raw materials involves trial, error, and sometimes rebuilding whole production lines.
By engineering Ethyl 4-Ethoxybenzoate to high consistency and purity, we provide users with a real improvement. For instance, food technologists call for aromatic esters that survive pasteurization, avoid off-tastes, and withstand UV exposure in packaging. In several collaborative projects, switching to our compound improved flavor stability, while reducing the risk of polymer migration or pigment fading in the final packaging. Sometimes this means working directly with formulation scientists, exchanging process data, and running pilot batches until issues resolve.
Pharmaceutical customers run into similar sticking points: too much variability in raw materials affects everything from tablet compressibility to finished product shelf-life. In projects where bioavailability of actives depends on controlled release, even slight alteration in ester hydrolysis kinetics can tip regulatory approval timelines. By supplying a product backed not just by numbers, but by real-world stress testing and field reports, our team has helped advance several projects past scale-up and into commercial launch.
Every molecule we send into the world begins with the same questions: is this product consistently safe and reliable, not just once, but through every delivery? Does our production set a benchmark for others? Responding to stricter regulations and customer demand for transparency, we have adopted process changes without waiting for external pressure. Those steps include using reclaimed energy from heat integration, advanced scrubbers for waste management, and full ingredient traceability in digital logs readable by auditors.
We don’t consider compliance a finish line, but part of the culture. Many customers check supplier credentials against global standards, but we encourage more serious dialogue: talking about in-process controls, environmental handling, and customer feedback loopbacks. Through consistent calibration against authorized reference standards, our QC team screens every batch for outlier peaks or inconsistencies in fingerprint spectra. These processes are shaped by real experience, not just literature, and tailored by feedback from specialists who demand not only functional purity but predictable handling during scale-up.
Price pressure and market competition mean that low-cost products from unrelated sources keep appearing. Some customers, driven by budget or procurement cycles, try a cheap alternative, but soon circle back after quality or process troubles emerge. Our longstanding relationships have often been built from situations where switching suppliers led to batch failures, regulatory delays, or downstream quality audits.
We have seen how direct investment in better reactors, cleaner packaging, and thorough document support makes a difference where shortcuts cause harm. This is not just about ticking boxes for audits. Every time a production line stops due to a contaminated raw material, or a shipment fails at port inspection, real costs and reputation are at stake. Decisions drawn from experience—interviewing line operators, listening to analytical chemists, and reviewing maintenance logs—mean every upgrade in our facility stems from real needs our customers voice.
Over the years, partners have shared data after replacing a generic benzoate with our Ethyl 4-Ethoxybenzoate, reporting fewer off-spec incidents, reduced need for costly in-line filtration, and better downstream blending. In one example, a flavor compounder noted a halt in customer complaints about fading aroma, directly tied to the improved solubility profile and greater batch consistency. Another team of formulation chemists working in sunscreen product development found that their new SPF blend resisted UV-induced changes longer, which they traced to our tightly controlled synthesis and absence of trace metals.
Making a molecule in the plant is only half the story. Users encounter practical issues at every stage: unloading, storage, transfer, dosing, and incorporation into complex matrices. Feedback collected from long-term partners has informed both our palletizing methods and small improvements in drum design. One customer reported easier handling from our new dual-cap containers, which keep the product free from atmospheric moisture yet allow for rapid venting and addition during high-speed processing. Packaging matters, especially for compounds like Ethyl 4-Ethoxybenzoate that must avoid contamination from dust, light, or residual humidity.
Temperature control during transport and storage preserves chemical stability—no one values a high-purity molecule that yellows or forms haze under warehouse lights. We suggest storage temperatures based on real-world trials, not just literature, and keep every batch tracked through our logistics team for location and time-in-transit. On request, we share data from controlled tests, showing the stability window even after multiple cycles of opening and resealing drums. This continuous investment in monitoring and response stems from a manufacturing culture used to speaking directly with the teams using the compound, not just brokers or traders.
While alternatives like methyl and propyl esters, or classical benzoates, fill many roles in factories and laboratories, Ethyl 4-Ethoxybenzoate bridges a unique middle ground. Compared with methyl esters, this molecule gives gentler solubility for sensitive actives, and dissipates less harshly in blends. Against straight ethyl benzoate, its extra ether group avoids some of the separation and stickiness reported in dense formulations. It slots well into current Good Manufacturing Practice protocols, since it leaves behind minimal extractables or leachables, and works in both glass-lined and stainless-steel vessels over a wide range.
Seasoned buyers pay attention to reproducibility and ease of qualification. With every process adjustment and lot validation, our team updates its procedures and documentation to close the gap between laboratory intent and real plant capability. This isn’t about chasing trends, but covering the basics: pure product, clear handling guidance, and open communication about potential incompatibilities or secondary reactions. We don’t just send a product sheet and walk away. For multi-tonne annual contracts, regular site visits, sample sharing, and technical calls ensure expectations stay aligned.
No chemistry operates in isolation. Regulatory changes, new applications, and customer innovation all feed back to how we manufacture Ethyl 4-Ethoxybenzoate. As use expands beyond flavors and pharma into specialty polymers and advanced coatings, we invest in new analytical tools—better HPLC methods for trace residuals, automated retention time checks, and extra screening for low-level odor contaminants. Where past producers might ignore lot-to-lot anomaly reports, we act early, even running simulations or extra pilot batches to investigate.
Our philosophy places customer and user experience at the center of improvement. Not every issue shows up in standard tests; sometimes a change in stirring time, drum headspace, or even site water supply creates an issue undetectable in small lab runs. By encouraging reports, no matter how minor, we have avoided bigger production mishaps, and tuned each new process. In the competitive landscape for advanced aromatics, direct manufacturing experience shows up in unanticipated places—from the comfort of an operator handling drums, to the lack of complaints from end-users down the chain.
Ethyl 4-Ethoxybenzoate tells a story about experience in manufacturing, honest partnerships, and continuous attention to detail. Across pharmaceuticals, food technology, personal care, and industrial chemistry, its value depends on real purity, predictable behavior, and responsive support. By focusing on the concrete issues that real users face, and shaping production and delivery around those, we keep our standard high. The feedback loop remains open, and every new application or hurdle drives further improvements not just in product, but in the way we work.