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HS Code |
536426 |
| Chemicalname | Ethyl 4-Aminocinnamate |
| Casnumber | 2206-28-0 |
| Molecularformula | C11H13NO2 |
| Molecularweight | 191.23 g/mol |
| Appearance | Light yellow to beige solid |
| Meltingpoint | 104-107°C |
| Boilingpoint | 383.4°C at 760 mmHg |
| Purity | Typically ≥98% |
| Solubility | Soluble in organic solvents (e.g., ethanol, methanol, DMSO) |
| Density | 1.14 g/cm³ (approximate) |
| Smiles | CCOC(=O)/C=C/C1=CC=C(C=C1)N |
| Inchi | InChI=1S/C11H13NO2/c1-2-14-11(13)7-6-9-4-3-8-10(12)5-9/h3-8H,2,12H2,1H3/b7-6+ |
As an accredited Ethyl 4-Aminocinnamate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Ethyl 4-Aminocinnamate, 25 grams, is packaged in a sealed amber glass bottle with a tamper-evident cap and detailed labeling. |
| Shipping | **Shipping Description for Ethyl 4-Aminocinnamate:** Ethyl 4-Aminocinnamate should be shipped in tightly sealed containers, protected from direct sunlight, moisture, and incompatible substances. Transport under cool, dry conditions, following regulations for organic chemicals. Ensure proper labeling and safety documentation are included to comply with local, national, and international shipping requirements. |
| Storage | Ethyl 4-Aminocinnamate should be stored in a tightly sealed container, protected from light and moisture, and kept in a cool, dry, and well-ventilated area. Avoid exposure to strong oxidizing agents and incompatible substances. Store at room temperature, away from direct heat sources. Properly label the container and follow standard laboratory safety protocols for the storage of organic compounds. |
Applications of Ethyl 4-Aminocinnamate in Industrial ManufacturingEthyl 4-Aminocinnamate serves as a pivotal specialty intermediate for multiple sectors, functioning primarily in pharmaceutical synthesis, cosmetic active ingredient production, UV-absorbent resin compounding, and advanced dye manufacturing. As an original producer, we ensure traceable process control and consistent specification matching for each real-world application scenario outlined below, supporting precise B2B requirements on a global scale. 1. Pharmaceutical Intermediates for Non-Steroidal Anti-Inflammatory Drug (NSAID) SynthesisOur Ethyl 4-Aminocinnamate is widely utilized as a key building block in the synthesis of newer classes of NSAIDs and anti-rheumatic agents, particularly within the context of laboratory-to-commercial GMP route optimization. Given its aromatic amine functionality and cinnamate scaffold, formulators rely on it to introduce bioactive moieties during multi-step synthesis of target APIs. Batch consistency and impurity control are monitored via in-process QC analytics tailored to pharma sector requirements. Industry compliance standards
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2. Cosmetic Active Ingredient Precursors (Whitening and Anti-Aging Agents)Within the skin care and personal care ingredient sector, formulators deploy our Ethyl 4-Aminocinnamate as a synthetic intermediate for targeted actives with photoprotective and melanin-inhibition profiles. The material participates in the construction of UV-absorbing complexes and is subsequently functionalized to create stabilized whitening additives. Batch documentation and regulatory traceability are supplied for downstream integration with established cosmetic safety frameworks. Industry compliance standards
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3. UV-Absorbing Polymeric Materials for Coatings and PlasticsCompounders in high-performance coatings and specialty plastics manufacturing rely on Ethyl 4-Aminocinnamate for its cinnamate core, which is transformed during polymer modification to introduce UV-absorbing moieties. The compound enables precise customization of UV-blocking polymeric resins used in outdoor-durable coatings and transparent protective films. Custom quality assurance protocols confirm residual monomer and migration limits across the supply chain. Industry compliance standards
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4. High-Performance Dye and Sublimation Ink IntermediateIn synthetic dye and specialty ink manufacture, the material acts as a differentiated intermediate for producing aminocinnamate-derived chromophores utilized in high-value colorant families. Dye formulators select this compound for introducing amino-substituted aromatic units, essential for tunable wavelength absorption in textile or graphic printing applications. Quality control is structured to guarantee batch reproducibility, crucial for multistep dye finishing processes. Industry compliance standards
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Competitive Ethyl 4-Aminocinnamate prices that fit your budget—flexible terms and customized quotes for every order.
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Working in chemical manufacturing for years, I’ve seen formulas come and go, but Ethyl 4-Aminocinnamate has proven its place in labs and production lines. Its chemical structure—a cinnamic acid derivative—sets it apart from the crowd. Customers regularly approach us asking for dependable raw materials, and this compound shows up on requisition sheets from clients working in dyes, pharmaceuticals, and specialty chemicals. We roll these batches from our own reactors, keeping a close eye on each critical step.
We take note of subtleties between Ethyl 4-Aminocinnamate and the broader field of related cinnamate esters. Familiar analogues, such as the methyl or butyl variants, may endure similar core synthetic steps, but they don’t offer the same molecular interactions for certain applications. Ethyl 4-Aminocinnamate stands out primarily thanks to the amino group, which adds masked basicity and unique reactivity. This subtle difference opens doors. Our customers tap into this feature for pharmaceutical intermediates, leveraging the para-position amino for more tailored reactions—acylations or couplings that support extended chemical syntheses.
For specialty dyes, our partners in pigment formulation find this compound brings depth or subtle undertones that other cinnamates can’t match. Some ester analogues don’t anchor or perform as well when exposed to sunlight or solvents. Users point out that our Ethyl 4-Aminocinnamate holds fast in expected and some surprising ways, which helps cut downstream batch failures.
Every batch we deliver stems from a process honed over years. From the earliest stage, purity matters. We source raw 4-aminocinnamic acid grades only from vetted upstream manufacturers, tracing every shipment and running it through a series of internal pre-tests before it heads to our line. By choosing only high-spec acids, we’re not left troubleshooting issues that can trail in when shortcuts are taken upstream.
Ethyl 4-Aminocinnamate isn’t one of those chemicals where a few tenths of a percent impurity can pass unnoticed. Both the color and odor give away problems quickly. A faint yellow tinge or off-note on the nose signals a need for process adjustment. Our team runs thin-layer chromatography and other spot checks multiple times each lot. Batches not clearing standards never reach packaging.
Solvents we use for esterification—often ethanol—must also meet benchmarks beyond the commodity-grade varieties. If there’s minor water or organic contaminant content in the solvent, the reaction will yield unwanted side products or—worse—unreacted starting material. Over time, careful process control has cut rework and waste. The result: reproducible purity and color our customers count on.
Think of this as a robust, reproducible product, not a lab novelty. Our standard batches go out as a white to faintly off-white powder. Typical melting point sits above 140°C, reflecting solid packing, while NMR and HPLC readings show identity and trace contaminants at or below 0.5%. Most lots hold up to accelerated stability assays, providing reassurance for customers who need long-term stock.
Granule size, moisture content, and flow matter for production-handling machinery. We ship this in container weights and cuts designed for ease of use in chemical reactors, so customers rarely deal with annoying static or bridging in hoppers. Incoming QA teams often probe with their own methods, and we regularly host them through inspections or audits.
Once the aminocinnamate skeleton is incorporated into a reaction, that para amino group often becomes a keystone for further chemistry. For example, pharmaceutical R&D teams synthesize amide or carbamate derivatives for small-molecule drugs. Our compound supports those multi-step sequences efficiently, since the amino group tolerates moderate conditions but still jumps into specific coupling reactions on demand.
The structure also caters well to UV-absorbing polymer work. Customers say that ethyl substitution confers particular solubility in organic phases, making it easier to blend, cast, or extrude. The amino’s electron-donating nature shifts spectral properties, which explains requests we receive from firms focused on sunscreen ingredients or light-stabilizing additives.
Our colleagues in pigments or dyes adjust production using small tweaks to this building block. By offering a consistent ethyl group instead of bulkier or smaller esters, they can tune shades that hold over repetitive processing. They know that batch-to-batch color drift can arise from minute shifts in molecular structure, and trust our QC to maintain tight tolerances.
Ethyl 4-Aminocinnamate earns its spot on production lines that require more than a generic ester. For firms evaluating cinnamate options, questions often revolve around reactivity and downstream compatibility. We find, through direct feedback, that butyl or methyl analogues fumble where precision is needed, especially in advanced pharmaceuticals or fine chemical synthesis.
The specificity of amino functionalization adds a flexibility few other cinnamates can match. Substituting the ethyl group for something larger or smaller reshapes both melting point and solubility. Those changes complicate crystallization and purification, making the chemical harder to manage outside ideal lab conditions. We adapt our process to guarantee uniform granule distribution and low dust, displacing problems customers have faced when dealing with alternative materials from bulk resellers.
Post-production, Ethyl 4-Aminocinnamate doesn’t just get bottled and moved out the door. Our technical staff assist users in troubleshooting solubility and mixing concerns unique to their site or process. Certain industries operate under strict regulatory or purity requirements, so we host open communications and share analytical documentation and batch data. Over time, that transparency cements extra confidence—especially for buyers who need lot-to-lot reproducibility.
Shipping across borders involves more than labeling drums. Many clients need documentation showing compliance with REACH or other chemical directives. We work with them at the pre-shipment stage to secure declarations, SDS verifications, and any extra technical paperwork. Avoiding customs surprises or wasted time reflects the level of support manufacturers should offer.
Inside our own walls, missteps tend to happen whenever process tightness is overlooked. A few years back, an overlooked solvent impurity resulted in a run where yield and purity fell flat. Only after matching HPLC traces to raw material audit reports was the root cause clear. This long process sharpened our incoming QC—now, every solvent drum is checked inline with our production schedule, not after problems start.
Clients come to us, sometimes frustrated by batch-to-batch inconsistency from previous suppliers. We have seen cases in which pigment formulators spent weeks tracing a fading issue in a specialty color latex. The culprit turned out to be an impure source of a similar ester. After switching over, their failure rate dropped, and our product’s spectral stability kicked in. Such direct feedback serves as both endorsement and challenge—we must stay diligent, since so many downstream operations hinge on details others might dismiss.
Some sectors want custom modifications for their own processes. Rather than offering a take-it-or-leave-it approach, we collaborate—altering particle size, moisture profiles, or even minor impurity spectrum. For instance, one client developing a new class of photoactive materials requested a specific sieve cut and asked that we revalidate trace byproducts below a tighter than usual spec. After discussions and lab-scale runs, we scaled their needs up without compromising our standard quality protocols.
Another example: Pharmaceutical firms sometimes need documentation trails extending back multiple years for regulatory review. Our archiving system—kept both digitally and with physical chromatography records—supports this. We welcome auditor visits and make our staff available to discuss fine points of synthesis and control. Experience has shown that proactive transparency makes problem-solving smoother for all parties.
Stepping outside of technical specs, the role of Ethyl 4-Aminocinnamate boils down to reliable performance under real working conditions. Customers turn to us for more than a chemical; they want assurance that their next batch, run, or reaction won’t fail because of unseen shifts. Some chemicals in this industry ride the commodity price rollercoaster or suffer from seasonal shortages, but by managing both upstream and in-house supply chains, we can weather those swings and shield clients from unexpected gaps.
Long-term relationships with users come from more than just delivering a chemical that meets a list of numbers. Over years, we’ve learned how different sectors want their own modifications or assurances—be it in ratios of isomers, volatility limits, or even the way the product flows from a drum to a reactor. Each application teaches us more about what gets the best results out of Ethyl 4-Aminocinnamate, and we fold that knowledge back into our production routines.
The chemical marketplace keeps growing. Synthetic chemists and materials scientists continually push for derivatives that boost efficiency or unlock new end products. Our willingness to gather and act on customer feedback helps us stay adaptable. We invest in lab time chasing incremental improvements, like refining filter media for better clarity or reassessing drying curves for more uniform moisture.
Clients also turn to us for support well beyond shipping. Sometimes they need help troubleshooting scale-up issues after moving from R&D up to pilot or commercial runs. We lend our own plant technicians or share detailed process notes to head off avoidable missteps. If a batch underperforms at customer facilities, we retrace records together, sharing raw trace data and offering to retest split samples—no call to a remote service desk, just direct team-to-team solutions.
Ethyl 4-Aminocinnamate, like most aromatic esters, needs careful handling protocols. Our teams follow strict health and safety measures at every production stage—ventilated reaction vessels, active fume recovery, and full PPE training. Over time, we’ve upgraded plant ventilation and installed real-time emission monitors, cutting the risk of exposure for both staff and the environment. Local regulators review our records on scheduled visits, and these reviews spark ongoing improvements.
Safe handling and efficient waste treatment ensure incidents remain rare. By investing in solvent recovery and dispatching spent materials for licensed incineration or reclamation, we limit both footprint and regulatory risk. Customers benefit from this care by receiving documentation tracing all raw and processed materials, which simplifies their own audits.
Manufacturing this fine chemical requires attention to every link in the chain. By keeping the process in-house—from raw acid selection, through controlled esterification, to quality packaging—we know exactly what leaves our gates. Our operators understand every reaction nuance, spotting stickiness in a filter or minor color shifts in pre-product stages.
Long-term service goes beyond good intentions. Recurring training for technicians and yearly review of process logs enable steady improvement. We don’t rest on old recipes but keep pushing for incremental gains, since industry standards and customer requirements never stay still. Honest conversations about quality and problem-solving set us apart from faceless bulk operations or impersonal resellers.
With regulations tightening and end-users seeking greener, more consistent materials, Ethyl 4-Aminocinnamate must earn its place each year. We adapt our processes to meet new benchmarks—purity thresholds, traceability, and sustainable practices. Research partnerships with university teams let us anticipate where regulations may drive future production, so we remain a step ahead and ready for whatever shifts the field presents.
Manufacturers who commit to genuine quality—from small batch to bulk order—ultimately fuel end-users’ success. We listen as customers share new project ideas or outline struggles with other suppliers. That communication leads us to refine our approach, test new production tweaks, or introduce expanded documentation. For every kilogram or ton shipped, we know a real project or business objective depends on that consistency.
Ethyl 4-Aminocinnamate, in our experience, sits among the more demanding—but rewarding—chemicals to produce and supply. Each order represents risks managed, details checked, and collaborative support for users working across industries. We stand by our process and product, always looking to improve and meet the real-world needs that arise in dynamic, demanding sectors.