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Ethyl 3-Methylthiopropionate

    • Product Name Ethyl 3-Methylthiopropionate
    • Alias ethyl 3-methylsulfanylpropanoate
    • Einecs 246-413-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    940125

    Productname Ethyl 3-Methylthiopropionate
    Casnumber 13333-84-7
    Molecularformula C6H12O2S
    Molecularweight 148.22
    Appearance Colorless to pale yellow liquid
    Odor Fruity, sulfurous
    Boilingpoint 178-180°C
    Density 1.032 g/cm3 (20°C)
    Refractiveindex 1.4390 (20°C)
    Solubility Insoluble in water; soluble in ethanol and ether
    Flashpoint 71°C
    Purity Typically ≥ 98%
    Storagetemperature Store at 2-8°C
    Smiles CCOC(=O)CCSC
    Uses Flavor and fragrance intermediate

    As an accredited Ethyl 3-Methylthiopropionate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Ethyl 3-Methylthiopropionate, 500 mL, is supplied in a sealed amber glass bottle with a secure screw cap for safe storage.
    Shipping **Shipping Description for Ethyl 3-Methylthiopropionate:** Ethyl 3-Methylthiopropionate is typically shipped in sealed, chemical-resistant containers to prevent leaks and exposure. It should be stored and transported in a cool, dry, well-ventilated area, away from direct sunlight, heat, and incompatible substances. Handle according to local regulations for flammable liquids and chemicals.
    Storage **Ethyl 3-methylthiopropionate** should be stored in a cool, dry, well-ventilated area, away from heat and sources of ignition. Keep the container tightly closed and out of direct sunlight. Store separately from strong oxidizing agents, acids, and bases. Ensure proper labeling and secure storage to prevent spills or unauthorized access. Use only approved, chemical-resistant containers for storage.
    Application of Ethyl 3-Methylthiopropionate

    Applications of Ethyl 3-Methylthiopropionate in Industrial Manufacturing

    Ethyl 3-Methylthiopropionate finds focused utilization across select industrial fields where its distinct chemical properties support targeted downstream formulations and processes. As an experienced manufacturer, we ensure consistently pure supply meeting specific technical criteria for each of these sectors.

    1. Food Flavorings and Additives

    Food ingredients manufacturers utilize this material chiefly in the development of savory and fruit-type flavor formulations due to its stable thioester profile and natural odor nuances. Incorporated during the flavor creation or compounding stage, it lends authentic onion, tropical fruit, and vegetable notes essential to processed foods and snacks. Formulators fine-tune inclusion rates to comply with global regulatory limits while maintaining desired sensory output, and rigorous QC measures verify batch conformity ahead of release for edible applications.

    Industry compliance standards

    • FAO/WHO JECFA Food Additive Specifications (Flavouring Group Evaluation)
    • European Commission Regulation (EC) No 1334/2008 (EU Flavouring Regulation)
    • US FDA 21 CFR Part 172.515 (Synthetic Flavoring Substances and Adjuvants)
    • China GB 2760–2014 (National Standards for Food Additives)

    Typical usage ratio

    • 0.01%–0.05% in finished flavor compounds. Final dosage in food products rarely exceeds 5 ppm (subject to food matrix and target market regulation).

    Downstream process integration

    • Added at the compounding/mixing stage of liquid or encapsulated flavor preparations.
    • Dispersed in solvent systems or oil-based carriers before homogenous blend with other aromatics or carriers.

    Final product types

    • Seasoned snack coatings
    • Processed cheese and dairy flavorings
    • Canned soup bases
    • Prepared meat analogues and instant meal kits

    2. Fragrance Compound Manufacturing

    Perfumery houses and aroma chemical blenders leverage the sulfur note and fruity undertones for use as an impact modifier in fragrance accords, particularly those designed for green, tropical, and savory olfactory families. Batch-specific titration ensures that the material’s unique volatiles integrate harmoniously, and vapor phase GC monitoring prevents off-odor development at elevated concentrations. Procedural adjustments align with IFRA restrictions and region-specific labeling mandates, making supply chain record-keeping critical.

    Industry compliance standards

    • IFRA Standards and Restriction Tables for fragrance materials
    • EU Cosmetics Regulation (EC) No 1223/2009
    • Cosmetic Ingredient Review (CIR) Safety Status (United States)
    • REACH Registration (where applicable within the European Economic Area)

    Typical usage ratio

    • 0.002%–0.015% in finished fragrance concentrates; actual load varies based on desired note strength and formulation base (alcohol, wax, oil).

    Downstream process integration

    • Dosed during the aromachemical compounding phase; weighed to the milligram level for micro-batch signature formulae.
    • Integrated with fixatives and other volatiles in cold or warm blending tanks to prevent volatilization losses during high-shear mixing.

    Final product types

    • Fine fragrance bases (eau de toilette, parfum sprays)
    • Home fragrance mists
    • Industrial air freshener cartridges
    • Laundry and cleaning product scents

    3. Animal Feed and Attractant Formulations

    Specialty feed and fishing lure manufacturers rely on the distinctive volatile sulfur compound profile to enhance palatability or baiting efficacy in animal nutrition and angling segments. Added in micro-quantities during trace additive blending of feed pellets or coated onto artificial baits, it generates a strong hedonic cue that triggers the feeding response in target species. Formulators recalibrate dosage according to species’ tolerance and local residue guidelines, while process monitoring ensures uniform distribution without exceeding maximum residual limits.

    Industry compliance standards

    • EU Regulation (EC) No 767/2009 (Placing on the Market and Use of Feed)
    • US FDA Feed Additive Petitions and GRAS Notifications
    • Association of American Feed Control Officials (AAFCO)
    • China GB/T 13078–2017 (Feed Hygiene Standards)

    Typical usage ratio

    • 0.001%–0.02% in complete feed or lure premix; adjusted lower for sensitive or juvenile life stages.

    Downstream process integration

    • Introduced at the micro-additive premixing station, followed by blending into bulk feed granulate or direct spray-application onto baits post-extrusion.
    • Homogenized via ribbon blenders or rotary drum coaters to achieve consistent batch distribution.

    Final product types

    • Fish and shrimp feed pellets
    • Mammalian livestock supplemental feed
    • Artificial aquatic lures (soft baits, dough baits)
    • Poultry attractant/fodder premixes

    4. Solvent-Based Chemical Synthesis Intermediates

    Many specialty chemical producers include Ethyl 3-Methylthiopropionate as a building block or reactive intermediate for the construction of fine chemicals, pesticides, or pharmaceutical side chains. It enters reaction sequences via controlled esterification, transesterification, or thio-alkylation steps, often under inert atmosphere to maintain thioester purity. Dosage responds to stoichiometric requirements, and integration at critical reaction points minimizes process impurities and ensures reproducibility for downstream isolation or purification operations.

    Industry compliance standards

    • Good Manufacturing Practice (GMP) for Intermediates (ICH Q7, WHO, China GB/T 29490–2013)
    • EPA TSCA Inventory Requirements (United States)
    • REACH Registration and Intermediate CoRAP (Europe)
    • ISO 9001:2015 Quality Systems for chemical manufacturing

    Typical usage ratio

    • Varies according to product synthesis; generally used as a limiting reagent at 1.0–1.5 equivalents per mole of target intermediate.

    Downstream process integration

    • Charged into reaction vessel after initial charge of solvent or base/acid catalyst; maintained under controlled temperature for selective reaction.
    • Can be purified from the reaction matrix for subsequent functionalization in multi-step synthesis chains.

    Final product types

    • Custom thioester-based fine chemicals
    • Agrochemical intermediates
    • Pharmaceutical side-chain precursors
    • Specialty solvent blends for industrial use
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    Certification & Compliance
    More Introduction

    Ethyl 3-Methylthiopropionate: A Closer Look from the Factory Floor

    Introduction to Ethyl 3-Methylthiopropionate

    In our experience producing high-value aroma chemicals for the flavor and fragrance industries, Ethyl 3-Methylthiopropionate has carved out its own distinct place. In the plant, every batch comes with its own subtle aroma, mixing crisp fruit notes with a rounded, slightly savory hint—a scent technicians usually recognize as soon as the reactor is opened. This molecule doesn’t just stand out on paper; it brings real sensory depth to product formulations and consistently demonstrates robust performance in manufacturing environments.

    Known in laboratories and on technical sheets as Ethyl 3-Methylthiopropionate, this compound—model number EMTP-23 here at our facility—offers both character and reliability. From the view of a chemical manufacturer, we focus less on technical generalities and more on how such products actually work in production and how our partners in flavor and fragrance houses use them.

    Specifications Experienced in Daily Production

    Each lot produced at the plant follows rigorous control steps from raw materials to final packing. Fresh EMTP-23 comes as a clear, colorless to faintly yellow liquid. Its molecular formula, C6H12O2S, yields a stable boiling profile and a predictable, easily managed handling threshold in industrial settings. Specific gravity hovers consistently in a narrow range, and batches show a reliable refractive index, confirming solid purity. Our internal GC analysis aims for an assay of at least 98%, which aligns with what we find effective for downstream users—both for compounding and scale-up runs.

    Lab staff recognize this product’s low water solubility but practical miscibility in key fragrance solvents and food-safe carriers. Because we monitor sulfur content and trace impurities at every step, the final output avoids unwanted off-notes, which matters when it’s added to delicate fruit flavors or precise perfumery bases. Workers value the product’s predictable flow and lack of tendency for unpredictable solidification under normal warehouse conditions.

    Making and Handling in the Manufacturing Environment

    EMTP-23 gets produced through a well-controlled esterification reaction, marrying 3-methylthiopropionic acid with ethanol under catalysis. The process turns on reliability—reactor pressure, clean separation, and minimized side-products guarantee consistent lots. Operators at the plant spend a good deal of time fine-tuning distillation columns and monitoring overhead condensate, since even minor deviations in process temp or ethanol feed rates can nudge the aromatic profile off-spec. Purging the lines prevents cross-contamination with unrelated batches, often for other thioesters or esters, so that flavors in the drum match what formulators want in their labs.

    Material transfer—including loading, dilution, and filtration—demands care. The pungency of the raw intermediates means operators and QC analysts use selective air handling and work with fitted filtration gear. It comes down to respecting both the chemistry and workplace safety; such practical details get little mention outside the plant but decide a batch’s final character.

    Why Flavorists and Perfumers Request Ethyl 3-Methylthiopropionate

    From experience supplying to flavor and fragrance companies, we notice EMTP-23 gets picked out for its unique way of amplifying ripe fruit, tropical, and pineapple top-notes. Formulators will often describe the aroma as running a line between ethereal pineapple and the richness of stone fruit. In practice, adding even low concentrations to base matrices can punch up the perception of juiciness and add depth missing from other esters. The thio- (sulfur) group, when balanced at high purity, lends an unmistakable lift that basic ethyl esters or methyl esters can’t reproduce.

    Professional blenders value EMTP-23’s ability to perform in both water-soluble and fat-soluble systems. Its volatility brings lively top-notes, but with enough persistence to avoid a fleeting effect. Fine fragrance houses regularly include it to imitate or approximate natural pineapple or guava notes in high-impact accords; in food applications, it’s a standard in artificial pineapple, combined tropical, and some strawberry flavors. Staff on the compounding floor prefer it to similar thioesters for this reason—it stays in solution and doesn’t break down prematurely when heated or stored under normal conditions.

    Other esters on the market serve as general fruit boosters, yet few manage the true-to-nature, slightly savory edge that this material gives. The sulfur backbone, managed properly during synthesis, is the secret ingredient separating an authentic finished aroma from a flat, generic ester blend on the shelf.

    Comparing with Other Flavor Ingredients: Practical Differences

    Having worked with both traditional and specialty esters, we see what makes EMTP-23 different isn’t just its flavor note. Ethyl butyrate and methyl butyrate, for example, show more volatile, sharper top-notes—good for instant fruitiness but lacking the rounded, slightly green finish that EMTP-23 achieves. These more common esters have a place in high-volume formulations, yet their lack of a sulfur component means any blend that tries to mimic certain tropical or pineapple profiles feels a bit hollow. Our technical clients, especially those recreating ripe and overripe fruit tones, depend on EMTP-23 to deliver what these simpler molecules cannot.

    Other thioesters, like methyl thiopropionate or ethyl thiobutyrate, tend to push the sulfur note past sweet and into meaty or cabbage-like territory. If a flavorist’s goal is fruity, those products often need masking agents or companion esters to keep them on the right path. EMTP-23 maintains the fruit-sulfur balance; it reads as clean pineapple from start to finish. Our own blends, tested against competitive samples, show the effect in real-world panel testing.

    Product stability also sets EMTP-23 apart. Unlike more reactive esters, which sometimes hydrolyze and degrade in compounded bases, batches from our facility show real staying power—whether shipped globally or stored in demanding climates. Our downstream partners report fewer off-notes and smaller changes in the aroma profile over time. Years spent refining our isolation and distillation steps have made a difference here, and we stick to straightforward steel drums and proper nitrogen blanketing to preserve every drum.

    Applications We’ve Seen in Real Production

    Flavor companies come to us with specific requests: pineapple for beverages, tropical for confectionery, occasionally for strawberry or apricot top-notes. We listen, and we see how EMTP-23 fits their requirements—sometimes as the star ingredient, more often as a strategic addition in a complex blend. In a soft drink base, it adds both immediate aroma and a lingering fullness that weaker esters can’t keep up with. In chewing gum, its flavor impact stands up even after extended chewing—a sign that the molecule’s persistence matches consumer expectations.

    Fine fragrance formulators don’t just chase fruit notes. They blend EMTP-23 into sophisticated compositions aiming for fresh, modern twists on classic tropical or citrus top-notes. We’ve had partners in South America and Asia, for example, who use EMTP-23 to construct modern colognes or light body sprays. They report that it delivers more authentic, mouthwatering freshness than comparable acetates or butyrates.

    On the technical side, our material’s purity and careful low-sulfur manufacturing means the finished fragrance or flavor doesn’t veer off into heavy, savory, or off-key notes. Culinary professionals looking for novel flavor impact—think beverage syrups and gourmet confections—have adopted EMTP-23, partly due to what end-users report as “fruit belt” authenticity. People familiar with infusing traditional fruit wines or rums sometimes seek out our product for experiments, since it pairs well with both natural and synthetic bases.

    One comment that comes up again and again from industrial processors is shelf life and stability. Working with EMTP-23 made here in our factory, bottlers and packagers see less oxidation, and the flavor stays on spec even after months in the warehouse. This is no accident—it results from careful raw material selection, disciplined catalysis steps, and quick turnaround from reactor to drum.

    Responsible Manufacture and Safety Observations

    In our own operations, responsible handling always means managing potential exposure to volatile sulfur compounds. Our team observes safe work standards and local environmental rules because the best product comes from a safe plant. We work with modern containment, local exhaust, and rapid response to any process upset so that every worker comes home safe and the environment stays protected. At the same time, finished material leaving our site meets or beats standard purity and stability benchmarks, so downstream processors deal with fewer quality complaints.

    Any chemical with a moderate odor profile brings questions about end use and safe handling. Long experience shipping bulk and drum quantities of EMTP-23 gives us insight into transport and storage needs. We use specialty drums and lined containers to avoid exposure to light and air, since this maintains the aroma profile and color for months. Technicians checking the warehouse work with sense and training, logging drum conditions and noting any signs of leaks or residue so that product loss seldom occurs. Bulk shipments follow both domestic and international hazard labeling, keeping everything both compliant and practical for unloading and blending.

    Real-World Challenges and Our Approaches

    Reliability—batch after batch—does not come easy. Raw material markets for 3-methylthiopropionic acid can show volatility, which means we maintain close supplier relationships and keep updated certificates of analysis on file. A few years ago, a shortage in specialty acids pressed the whole industry, but by standing by long-term suppliers and keeping buffer stock, our output stayed uninterrupted. Lessons learned from those tight periods focus our daily operations today; we keep analytical oversight high and do not rely on last-minute sourcing.

    Scaling up production in the plant means not just bigger tanks, but tighter process control. Minor impurities, the kind that slip past casual inspection, get flagged through our regular off-line GC and panel reviews. Manufacturing teams run small-scale simulation batches to test how process tweaks affect aroma so that even large-scale runs meet panel-tested criteria. Because odor drift or color change—often invisible on paper—matters more to the end user than a single point of purity, our QA teams pull early and late samples for comparison, not just the theoretical “middle” draw.

    We also work with industry partners to stay on top of new purity standards and regulatory policies. If European regulators shift the allowable sulfur threshold, or new Asian markets demand different specifications, we adjust. This flexibility comes from years of adjusting equipment and process flow, not just from newsletter updates or copying general practices. Our site engineers and lab managers compare international test methods, constantly updating how we calibrate equipment and sign off lots for shipment overseas.

    Waste minimization at the plant reflects both environmental responsibility and cost. Thanks to an improved recovery setup, much of the minor-loss fractions now get cleaned and recycled into non-critical batches or partner uses. Before, this would have gone straight to disposal, risking expense and unsafe venting. Applying more efficient vacuum distillation and filtration tech makes the process both cleaner and more affordable; plant operators see the difference not just in the reduced waste manifest, but also in the improved air quality of production halls.

    Industry Partnerships Shaped by Real Product Performance

    Customers who buy from us know that a product’s story travels with each drum. The technical documents show the facts, but real-world decisions get made when formulators compare the result—side by side—with alternative esters and thioesters. In head-to-head benchmarking for beverage compounding, our EMTP-23 routinely carries a more robust fruit impact and keeps its intended aroma after bottling. Repeat buyers mention shelf life and fewer flavor complaints at retail, not just the upfront price, as keys to their purchasing decision.

    Our R&D group tests new blends with both traditional and cutting-edge solvents, exploring how the product handles in everything from carbonated drinks to emulsified flavor carriers. These workers do not stop at theoretical compatibility; every prototype batch heads to lab panels and sometimes small commercial runs before feedback drives process improvements. Close feedback from expert tasters—whether for a soft drink, canned fruit, or a modern personal fragrance—guides our tweaks and upgrades. As the manufacturing base, we adjust process specs and raw materials with each cycle based on this consistent, hands-on feedback.

    Long-term partners often develop proprietary fruit blends unique to their house style, depending on our EMTP-23 as a central or supporting note. These flavorists trust that our manufacturing controls will keep the product specification tight, so their signature blend remains consistent season after season. By sharing batch-level QC and ongoing stability results, we help their technical staff plan long runs and avoid disruption—a real-world benefit not always matched by traders and generic suppliers.

    The Role of Ethyl 3-Methylthiopropionate in the Evolving Flavor and Fragrance Market

    Industry trends point toward more natural, authentic, and mouthwatering taste profiles. EMTP-23 lands right in the middle of this trend, with its close-to-natural pineapple and stone fruit notes. Customers developing next-generation plant-based beverages or reimagined classics for the snack aisle look for impact, authenticity, and regulatory compliance in every material. Our product’s robust performance in both application and regulatory compliance keeps us closely linked with evolving market expectations.

    Chefs and food technologists frequently reach out to explore how EMTP-23 can lift or transform traditional recipes. Its use in non-alcoholic beverages, functional drinks, and bakery fillings continues to grow. Artisanal and large-scale producers alike respond well to a product that doesn’t break down or throw off flavors in processing, storage, or finished goods. This points not just to the chemistry, but to the years-long process improvements at the manufacturing site. Staff here tweak reaction time, catalyst level, distillation fractions, and even drum coatings so every shipment retains power and clarity.

    Sustainability forms a growing part of market conversations. By reducing waste, targeting optimal yields, and working with responsible raw material suppliers, we answer not just business needs but broader social expectations. Engineers and staff on the ground focus as much on carbon management and energy use in production as they do on final yield. These matters are not just about compliance—they support the trust and ongoing loyalty of customers, both domestic and export.

    Improvements and Future Directions

    Plant modernization efforts center around automating tracking, shutting down off-spec production quickly, and using predictive analytics to improve lot consistency. Adoption of automated sensors and in-line GC means less guesswork and tighter control at each manufacturing step. Operators, following years of process tweaks and feedback from downstream users, can make small adjustments that carry through the supply chain in improved flavor, shelf life, and cost control.

    Reinvestment in technical capability forms another branch of our commitment to long-term quality. Staff at every level take part in regular cross-training and outside workshops, bringing back process ideas that keep our EMTP-23 at the forefront of industrial performance. This is especially important as global tastes shift, regulatory landscapes move, and the need for new applications grows. Our flavorists, cell managers, and control chemists collaborate with end users on prototype runs, flagging formulation challenges that may not be obvious from the outside.

    Responding to new research on food safety and off-flavor prevention, we make ongoing improvements to our production setup. By trialing advanced catalysts and more precise distillation cut controls, line managers spot small differences in output earlier. Technicians fine-tune how quickly intermediate byproducts are separated, ensuring aroma purity and minimal off-odor risk. These process upgrades seem small, but over hundreds of metric tons per year, they yield real gains in customer satisfaction and production sustainability.

    Takeaways from Years of Chemical Manufacture

    Working day in and day out with Ethyl 3-Methylthiopropionate teaches that the right technical choices—solid raw materials, trained staff, process discipline—translate directly into success for industrial users downstream. Its performance in beverage flavors, fruit-top perfumes, and even non-food aromas shows that a carefully made product always has a place in advanced formulation.

    What separates EMTP-23 from other market offerings? The balance between sulfur brightness and rounded fruit, reliable non-reactivity in blends, predictable delivery from drum to bottle, and a manufacturing process that listens to clients while maintaining the highest safety and environmental standards. Consistent, long-term improvements in plant practice and attention to feedback have shaped this molecule into a cornerstone for fruit-forward product development. These are realities seen not on data sheets, but in the daily operations and satisfied calls from returning customers in flavor, fragrance, and food manufacturing worldwide.