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Ethyl 3-Methylbenzoate

    • Product Name Ethyl 3-Methylbenzoate
    • Alias Ethyl m-toluate
    • Einecs 217-663-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    948501

    Iupac Name Ethyl 3-methylbenzoate
    Molecular Formula C10H12O2
    Molar Mass 164.20 g/mol
    Cas Number 2209-60-1
    Appearance Colorless liquid
    Boiling Point 238-239 °C
    Melting Point -12 °C
    Density 1.045 g/cm³
    Refractive Index 1.505
    Solubility In Water Insoluble
    Odor Pleasant, aromatic
    Flash Point 109 °C
    Pubchem Cid 16185
    Smiles CCOC(=O)C1=CC=CC(=C1)C

    As an accredited Ethyl 3-Methylbenzoate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Ethyl 3-Methylbenzoate, 100 mL, is packaged in an amber glass bottle with a secure screw cap and detailed safety labeling.
    Shipping **Shipping Description for Ethyl 3-Methylbenzoate:** Ethyl 3-methylbenzoate is shipped in tightly sealed chemical containers, typically made of glass or HDPE plastic. It should be protected from light, moisture, and incompatible substances. Transport in accordance with local, national, and international regulations for chemical safety. Proper labeling, including hazard identification, is required to ensure safe handling and delivery.
    Storage Ethyl 3-Methylbenzoate should be stored in a tightly closed container in a cool, dry, well-ventilated area away from sources of ignition, heat, and incompatible materials like strong oxidizers. Keep the container protected from direct sunlight and moisture. Proper labeling and secondary containment are recommended to prevent leaks or spills. Always follow standard laboratory safety procedures when handling and storing.
    Application of Ethyl 3-Methylbenzoate

    Applications of Ethyl 3-Methylbenzoate in Industrial Manufacturing

    Ethyl 3-Methylbenzoate serves as an aromatic ester intermediate widely adopted by industries where fragrance customization, specialty chemical synthesis, and precision quality control remain critical in production cycles. Below, we summarize its major downstream application scenarios as utilized by manufacturers in accordance with relevant technical standards and industrial practice.

    1. Fine Fragrance Compound Production

    Aroma compound manufacturers rely on Ethyl 3-Methylbenzoate as a stable, mild floral and fruity note extender in core fragrance oil recipes. Perfumers incorporate it during controlled blending at the compounding phase, balancing top and middle notes, particularly for niche perfumery, premium personal care, and detergent fragrance bases where the compound’s volatility and tenacity are valued. Quality control teams routinely screen input concentrations to confirm both olfactory profile and residual purity meet international fragrance house criteria.

    Industry compliance standards

    • IFRA (International Fragrance Association) Code of Practice
    • EU Cosmetics Regulation (EC) No 1223/2009
    • REACH Registration (EC) No 1907/2006 for allowable impurities and trace substances
    • ISO 9235:2013 (Aromatic raw materials – proper identification and purity)

    Typical usage ratio

    • 0.05–0.8% of total fragrance oil formulation; titration adjusted based on the desired persistence, target blend profile, and IFRA allergen thresholds; higher proportions for laundry and home care scents

    Downstream process integration

    • Batch blending and pre-dilution with other esters and alcohols during fragrance concentrate compounding; addition after filtration and before fixation phase; raw ester checked for clarity and odor before dosing

    Final product types

    • Personal perfumes and eau de toilette
    • Cream and lotion scenting bases
    • Functional fragrances for detergents, air fresheners, and candles

    2. Agrochemical Synthesis (Intermediate for Herbicides)

    Chemical manufacturers utilize Ethyl 3-Methylbenzoate as an intermediate in multistep syntheses for selective herbicide active compounds within benzoate or pyrazole derivatives. The raw material enters the synthesis train at the esterification or acylation stage, reacting with specific nucleophiles to yield building blocks for herbicides. Downstream R&D teams validate conversion yields, impurity profiles, and conformity to agrochemical registration specifications in target export markets.

    Industry compliance standards

    • FAO/WHO Specifications for Agricultural Pesticides
    • OECD GLP (Good Laboratory Practice) for synthesis documentation
    • EU Regulation (EC) No 1107/2009 (Plant Protection Products)
    • Chinese Ministry of Agriculture Pesticide Product Registration Standards

    Typical usage ratio

    • 1.5–7.5% by molar ratio in multi-step syntheses; ratio varies depending on specific herbicide target molecule and route selectivity; exact feed adjusted according to batch size and reactivity conditions

    Downstream process integration

    • Introduced into batch or continuous reactors at esterification or ring closure step; monitored by GC-MS to control conversion under anhydrous conditions; followed by separation, purification, and downstream derivatization for final active ingredient assembly

    Final product types

    • Benzoate-class herbicides
    • Preemergence and selective weed control agents
    • Technical active ingredients for agricultural formulations

    3. Pharmaceutical Intermediate for Active Ingredient Synthesis

    Pharmaceutical fine chemical companies employ Ethyl 3-Methylbenzoate as an intermediate in the formation of certain APIs and medicinal compounds within anti-inflammatory and antipyretic drug pipelines. The ester undergoes controlled hydrolysis and subsequent functional group transformation under GMP conditions, ensuring traceability and impurity minimization throughout the process to meet regulatory dossier requirements and pharmacopoeial monographs.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • Ph. Eur. (European Pharmacopoeia)
    • United States Pharmacopeia (USP) standards for raw material purity and identity
    • API DMF (Drug Master File) submission protocols

    Typical usage ratio

    • 0.8–3.2% (w/w) relative to total API precursor batch size; precise loading established per validated synthesis pathways and impurity control limits

    Downstream process integration

    • Added at initial condensation or ester hydrolysis reaction; process isometric samples tracked via HPLC to confirm complete conversion; involved in subsequent amidation or reduction based on API structural design

    Final product types

    • Intermediate-stage fine chemicals for pain relief formulations
    • Non-steroidal anti-inflammatory drug (NSAID) precursors
    • Custom small molecule pharmaceutical actives

    4. Industrial Dye Synthesis

    Specialty dye manufacturers adopt Ethyl 3-Methylbenzoate for the development of aromatic ester-based chromophores, particularly for use in disperse and solvent dye systems for textile, plastics, and fiber coloration. It is involved as a precursor in Friedel-Crafts alkylation and complementary benzoylation steps, ensuring color fastness and improved solubility across various substrate applications. Strict residue and isomer profiling remain important for compliance and performance durability.

    Industry compliance standards

    • OEKO-TEX Standard 100 (Textile Dye Safety)
    • ZDHC (Zero Discharge of Hazardous Chemicals) guidelines
    • GHS labeling for chemical intermediates
    • ISO 9001:2015 Quality Management for production traceability

    Typical usage ratio

    • 1.0–6.0% of dye intermediate mass fraction; adjusted in process development for target chromophore intensity, fastness rating, and desired hue specificity

    Downstream process integration

    • Charged into alkylation reactor step post-initial ring activation; reaction parameters tailored to maximize ester group transfer; unreacted material recycled for yield optimization; final dye intermediate purified through crystallization or vacuum distillation

    Final product types

    • Polyester and acetate fiber disperse dyes
    • Solvent-based colorants for engineering plastics
    • Textile printing inks and industrial pigment bases

    5. Flavor Ingredient Compounding for Non-Food Technical Flavors

    Manufacturers formulating technical flavor solutions for oral care, tobacco substitutes, and pet care products use Ethyl 3-Methylbenzoate for its subtle sweet-fruity background note. Its pure grade enters closed system blending during aroma base preparation, with input lot traceability monitored under flavor house and sector-specific flavor safety protocols. Panel and instrument tests confirm compliance with residual solvent and volatile standards required for indirect human contact applications.

    Industry compliance standards

    • FEMA GRAS certification (Flavour and Extract Manufacturers Association)
    • ISO 22000:2018 Food Safety Management (for indirect ingestion risk)
    • USP-NF excipient guidelines for technical applications
    • EU CLP Regulation 1272/2008 for labeling and classification

    Typical usage ratio

    • 0.015–0.12% of total flavor concentrate; dosed precisely to support the flavor’s top note without impacting regulatory residue limits; amounts modified after panel sensory trials and GC quantitation of volatile carryover

    Downstream process integration

    • Blended into master flavor base during compounding stage; solubilized in hydroalcoholic media or neutral oil, then homogenized before final dilution batch; monitored by QA to ensure absence of off-flavors or solvent residues

    Final product types

    • Toothpaste and mouthwash technical flavors
    • Smoke-free oral tobacco replacements
    • Pet treats and non-nutritive chew flavor coatings
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    Certification & Compliance
    More Introduction

    Introducing Ethyl 3-Methylbenzoate: A Manufacturer’s Perspective

    Crafting Quality at the Source

    In the world of fine chemicals, every molecule tells a story rooted in purposeful creation and hands-on experience. Ethyl 3-methylbenzoate stands out in our portfolio, bearing the mark of craftsmanship achieved on the synthesis line. We have long understood the importance of consistent purity, and with ethyl 3-methylbenzoate, attention to detail throughout each batch pays off in downstream reliability.

    The distinct advantage of manufacturing this compound in-house begins with our selection of base materials—toluene derivatives that arrive to our facility checked for low water content and verified origin. We run them directly through our controlled esterification process. Pre-treating our reaction vessels reduces the stray ion risk that can trigger color instability. This commitment to a clean process helps us deliver a colorless, almost water-clear liquid, maintaining close to 99% assay by gas chromatography standard. Our process removes extraneous acids and residual reactants, a step that keeps the final product stable in storage and transport.

    Operating on our own reactors gives us a unique opportunity to influence the subtle characteristics buyers care about. To minimize unwanted byproducts, we use an excess of ethanol with a gentle heat ramp, applying a proprietary catalyst blend to keep side reactions at bay. Resulting ethyl 3-methylbenzoate emerges with a fragrance profile appreciated in fragrance and flavor formulations—soft, sweet, and clean, sidestepping some harsher undertones seen in less refined material.

    Ethyl 3-Methylbenzoate in Application

    We see strong demand for this benzoate ester in the world of fine perfumery and flavors, as well as in certain pharmaceutical intermediates. Working directly with end-users, we have gathered practical feedback: researchers and product developers prize its solvency characteristics and its ability to enhance floral and fruity notes without lingering out of place. Our quality standard has developed from these conversations, and as a result, customers avoid issues such as bottle discoloration or process residue.

    Over years of batch experience, we have noticed that this product, when handled with clean glass and purged transfer lines, resists degradative hydrolysis far better than benzoates made in less-controlled circumstances. For flavor chemists, this translates into a dependable base note in compounds built around ethereal or nuanced profiles.

    Manufacturing brings certain insights to light you can’t find in textbooks. For example, ethyl 3-methylbenzoate easily dissolves in alcohols and ethers, but we learned from multiple test runs that it resists clouding in alcoholic solutions—one reason why niche beverage formulators often select our lots to add complexity to their recipes. It doesn’t interfere with primary flavors at low concentrations, and our minimal residual acid content prevents the off-odors that would otherwise disrupt a delicate blend.

    Understanding What Sets It Apart

    Ethyl benzoate and its methyl or ethyl substituted cousins form a family of aroma chemicals with subtly variegated performance. For those outside the world of specialty chemicals, the distinctions may blur. Through the eyes of a manufacturer, the differences influence every aspect from blending to end-use effectiveness.

    We maintain parallel production of ethyl benzoate and several methyl-substituted benzoates, for direct comparison. Ethyl 3-methylbenzoate’s methyl group at the meta position yields unanticipated strengths in fragrance design—its volatility sits between methyl benzoate’s rapid evaporation and ethyl benzoate’s slower, more lingering profile. This unique balance makes it a go-to component where rounded middle notes matter most.

    Practical evaluations by our technical group reveal finer differences, particularly in long-term storage and compatibility with both natural and synthetic blend partners. Ethyl 3-methylbenzoate shows exceptional stability under proper storage conditions, holding up against sunlight exposure and temperature variation in a way that some isomeric forms do not. Its odor retention supports perfumers working in the fine fragrance sector, where longevity without heaviness becomes critical.

    Pharmaceutical manufacturers have also highlighted its low toxicity and ready biodegradability, supporting the stricter regulatory environment in export destinations. No two esterification processes create identical impurity profiles, though, so our batch-by-batch certificate of analysis always reflects rigorous detection of potential residuals—especially unreacted acids, alcohols, and trace metals.

    Building the product ourselves encourages ongoing improvements. Equipment upgrades, such as continuous flow reactors, have let us reduce reaction time while shaving down energy consumption. By recycling unreacted alcohols from each run, we improve both economic efficiency and environmental impact, without shifting the essential qualities of ethyl 3-methylbenzoate that end-users require.

    Screening for aldehydic off-notes at the bench scale keeps those same material qualities consistent year after year. Customers in aroma and flavor industries express appreciation for this batch-to-batch reliability. Downstream, the clean profile eases compounding and analytical quantification, keeping regulatory submissions straightforward.

    Manufacturing Insights: Scale, Control, and Safety

    Direct involvement in the process reveals real-world challenges and opportunities. Operational scale has everything to do with reproducibility. Early batches, run on smaller glassware, sometimes yielded minor variations in color or byproduct content. Our transition to jacketed reactors, with precise agitation and temperature control, has virtually erased those discrepancies, offering both large- and small-volume buyers the same material.

    We follow strict protocols around material containment and line flushing, countering cross-contamination. Real-time in-line monitoring detects any drift in reaction parameters, which would otherwise translate to off-grade lots. Waste streams present an environmental challenge for any ester process, so we designed integrated solvent recovery units and modular activated carbon filters before releasing anything to the external system.

    Employee training and hazard recognition figure heavily in daily practice. Ethyl 3-methylbenzoate’s moderate volatility demands proper handling, both to preserve purity and to ensure personnel safety. By keeping work stations ventilated, maintaining personal protective gear, and deploying automatic leak-detection, we have driven down incident rates over the past decade. Insisting on technical fluency among operators allowed us to spot sources of minute contamination, including silicone-based greases from transfer pumps, well before they could affect a finished batch.

    Feedback from our plant laboratory has improved material selection for gaskets, hoses, and storage tanks, further shielding product from potential trace impurities or migration of unwanted substances. These details emerge only through repeated, direct engagement in the process, not through third-hand specification.

    Meeting Real-World Customer Demands

    End-users come to us from industries where traceability, performance, and ethical responsibility stand as the benchmarks for repeat business. In the fragrance field, expert noses search not just for a pleasant note, but for consistency from year to year—one failed formulation could set back months of development. Small differences in starting material, purification, and shipping conditions can shift the outcome. By maintaining a continuous dialogue with customers, we adjust process parameters or packing types to suit evolving application needs. For example, several major fragrance houses moved to eco-friendly solvents and demanded a product free from phthalate impurities. Adjusting our purification method by switching to certified phthalate-free solvents made this possible without loss of performance.

    Aromachemists and flavorists look for a chemical’s ability to round out notes and add longevity in a blend. Side-by-side with alternative substituted benzoates, ethyl 3-methylbenzoate brings a subtle sweetness, blending well without overpowering lighter floral or fruity aromas. This gentle character makes it popular for both high-end luxury products and everyday household fragrances.

    Pharmaceutical intermediates require close attention to purity and trace residuals. Our in-house process controls give us flexibility to dial down to parts-per-million on certain contaminants. Over the years, several customers have approached us with specialized requests: higher purity than usual, or a narrow specification range for solvents. Because we operate as the manufacturer, not as a reseller, we hold the tools to make those changes directly on our own line, sharing real batch data and open test results.

    Especially in regulated industries, a chain of documentation—from raw material receipt through finished-goods release—makes all the difference in audit situations. We maintain a digital record of each batch, cross-referenced with process logs and quality control snapshots, making postorder traceability straightforward for our clients.

    Environmental and Regulatory Responsibilities

    The pressure of global oversight and local environmental requirements shapes every part of the business. A modern chemical facility no longer gets by simply by turning out a high-purity product; the sustainability demands of our buyers push us to show long-term stewardship at every stage. Through years of emissions tracking, we identified areas of improvement. Solvent venting and wastewater standards rise year over year. We retrofitted our waste recovery lines to reclaim more than 90% of organic solvents, sharply reducing both emissions and transport costs for hazardous waste. Switching from traditional condensation cooling units to heat exchangers cut energy usage on largescale reactor loads. These changes reduced operational overhead, but also positioned us to support export clients needing evidence of sustainable production.

    Each region brings its own scrutiny about product contaminant limits. To comply with European and North American restrictions on specific trace byproducts, we set up continuous sampling and validated analytical protocols. Experience tells us that preemptively tightening internal specification limits, rather than running to meet minimum legal requirements, avoids shipment holds and supports smoother customer audits.

    Packaging and Delivery: Keeping Product Integrity Intact

    Our approach to packaging emerges from early lessons learned on the shipping floor. Quality doesn’t survive careless storage. We moved away from generic barrels, now filling on demand into high-barrier, food-grade containers equipped with nitrogen blankets to prevent oxidation during long transits.

    Temperature shifts and humidity encountered in transit prompted us to insulate both drums and intermediate containers. This has sharply reduced incidents of slight yellowing or cloudiness by the time the product reaches customers in tropical or high-humidity regions. For smaller lots, we bottle under a controlled environment, reducing moisture pickup.

    Accountability extends beyond the factory gate. Our logistics staff coordinate with reliable carriers, tracing each shipment and providing real-time updates. Incoming feedback from the field has led to packaging improvements, such as tamper-evident closures and unified labeling, which supports compliance documentation and client inventory management.

    Continuous Improvement and Industry Collaboration

    True innovation means learning from every batch. Our team regularly reviews process deviations—even rare ones—to improve our methodology. Periodic roundtables with end-users, industry analysts, and regulatory specialists surface new concerns. Sometimes those issues involve tightening residual solvent levels; sometimes, participants request documentation for new regional compliance thresholds. We use those opportunities to adjust our process and formalize new quality checks.

    Technical partnerships contribute fresh insights, too. Several years ago, joint studies with external flavorists led to a refinement in our distillation column packing, improving odor neutrality. Ongoing pilot projects sometimes push our material into niche applications we had not originally targeted—specialty coatings, intermediate materials for agrochemical candidates, and electronic industry resins, each with sharp constraints on trace metals and residual acidity.

    Benchmarks never remain static. As new analytical tools emerge, we invest to incorporate them into our regular program. Rather than rely solely on traditional titrimetric methods, we cross-check results with high-performance liquid chromatography and GC-MS, flagging even sub-visual impurities before they reach the packaging stage. This ongoing commitment supports the needs of users working in critical applications.

    Summary of Ethyl 3-Methylbenzoate’s Place in Modern Markets

    Years on the manufacturing floor show how the quality of a fine chemical like ethyl 3-methylbenzoate reflects not only careful synthesis, but also a commitment to regular feedback, process discipline, and environmental vigilance. Fine-tuning at each phase—from reactant selection, through clean process management, to post-production handling—builds the reliability end-users trust. Differences between similar benzoate esters influence more than just paperwork or pricing; they play out in bench stability, odor performance, regulatory compliance, and environmental responsibility.

    Direct production control provides us clarity on those features that keep ethyl 3-methylbenzoate essential in the toolkit of perfumers, flavorists, pharmaceutical manufacturers, and specialty chemical developers worldwide. In each case, real manufacturing experience translates into real product integrity, offering partners in every sector a chemical foundation they can trust.