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HS Code |
891878 |
| Cas Number | 113237-07-1 |
| Molecular Formula | C15H21NO2 |
| Molecular Weight | 247.33 g/mol |
| Iupac Name | Ethyl 1-benzylpiperidine-4-carboxylate |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 370.6°C at 760 mmHg |
| Solubility | Soluble in organic solvents |
| Density | 1.06 g/cm³ |
| Storage Temperature | Store at 2-8°C |
| Purity | Typically ≥98% |
| Smiles | CCOC(=O)C1CCN(CC1)CC2=CC=CC=C2 |
| Inchi | InChI=1S/C15H21NO2/c1-2-18-15(17)13-8-11-16(12-9-13)10-14-6-4-3-5-7-14/h3-7,13H,2,8-12H2,1H3 |
As an accredited Ethyl 1-Benzylpiperidine-4-Carboxylate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Ethyl 1-Benzylpiperidine-4-Carboxylate, 25g: Supplied in a sealed amber glass bottle with tamper-evident cap, labeled with hazard, purity, and safety details. |
| Shipping | Ethyl 1-Benzylpiperidine-4-Carboxylate is shipped in secure, chemical-resistant containers, compliant with local and international transport regulations. The packaging ensures protection from light, moisture, and contamination. All shipments include appropriate labeling, safety documentation, and handling instructions to ensure safe and legal delivery to authorized recipients. |
| Storage | **Storage Description:** Ethyl 1-Benzylpiperidine-4-Carboxylate should be stored in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible substances such as strong oxidizing agents. Keep the container tightly closed when not in use and store at room temperature. Use appropriate chemical-resistant containers and ensure proper labeling to avoid accidental misuse or exposure. |
Applications of Ethyl 1-Benzylpiperidine-4-Carboxylate in Industrial ManufacturingOur direct manufacturing expertise in Ethyl 1-Benzylpiperidine-4-Carboxylate supports specialized downstream applications where reliability in performance, compliance, and integration within production workflows is critical. The following industrial sectors reflect mature, well-documented uses in which this material consistently fulfills formulation, regulatory, and functional requirements. Each application scenario is listed below with precise details regarding standards, usage levels, process flow, and finished products as encountered in real-world industrial environments. 1. Pharmaceutical Intermediate for Piperidine-based API SynthesisEthyl 1-Benzylpiperidine-4-Carboxylate serves as an advanced intermediate in the synthesis of piperidine-containing active pharmaceutical ingredients. Its structural motif is an essential scaffold during the preparation of several CNS-targeting compounds and selective ligand frameworks. Integration into pharmaceutical reactions demands strictly defined purity, traceability, and reactivity profiles to ensure batch-to-batch consistency and support downstream API isolation steps. Industry compliance standards
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2. Intermediate in Agrochemical Synthesis (Herbicide Precursor)The compound is utilized as a functionalized nitrogen source in the synthesis of complex agrochemical actives, specifically within herbicide and plant protection molecule families requiring benzylpiperidine moieties. Manufacturers value its high selectivity in semi-continuous condensation or reductive amination, supporting both scalability and consistent purity for large-volume campaigns. Industry compliance standards
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3. Fine Chemical Building Block for Specialty PolymersWithin specialty polymer synthesis, the compound acts as a functional monomeric building block introducing tailored nitrogen-bearing side chains onto polymer backbones. Its controlled hydrolysis and facile incorporation support targeting specific polymer properties such as adhesion, controlled release, or antistatic behavior. Large-scale production lines depend on highly consistent supply and strict QC controls. Industry compliance standards
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4. Precursor in Chiral Auxiliary Synthesis for Asymmetric CatalysisChiral auxiliaries derived from this carboxylate ester facilitate enantioselective transformations in both API and fine chemical manufacture. Chemical engineering teams benefit from the controlled reactivity profile enabling precise stereochemical outcomes essential for downstream catalytic hydrogenation or alkylation steps. Industry compliance standards
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5. Intermediate in Synthesis of Research Chemicals for NeuroscienceThe raw material forms a critical intermediate in controlled multi-step synthesis of research compounds with central nervous system activity, supporting R&D teams in pharmaceutical discovery or academic projects. Its structural features accommodate benzyl and piperidine fragments required to probe receptor binding and neurotransmitter modulators. Industry compliance standards
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In the chemical business, production quality does not come down to paperwork in an office. It shows up in every batch, every test, every awkward pause on the factory floor when something needs adjusting. We’ve run our plant for years making Ethyl 1-Benzylpiperidine-4-Carboxylate (E1BPC), and the more we produce, the clearer it becomes why this compound stands out from the crowd. In our experience, talking specs only goes so far; what matters most is how the product performs when chemists get their hands on it. E1BPC has earned its place in our range not just because of its chemistry but also for the consistent, clean performance it delivers.
Once the raw feedstock arrives at our facility, we don’t trust anything on face value. Every batch passes through raw material verification, not just paperwork but direct analysis. E1BPC takes time in the reactor, and every variable—temperature, agitation speed, pH balance—makes a real difference you can measure in the end product. Our operators have learned the quirks of this synthesis, and careful monitoring keeps us from surprises downstream. The resulting crude gets refined through pressure filtration, then moved into vacuum distillation. This isn’t textbook theory: it’s built on hundreds of trial runs, late nights, and small adjustments that cut out side reactions and bring the purity up. Once it leaves the line, it’s not just a chemical but the result of sweat and plenty of hard-earned lessons.
On paper, E1BPC reaches the market as a clear, high-purity liquid with a tightly controlled boiling point. Because we run our own analytics, every drum we ship carries a record not just of what it’s supposed to be, but how it actually turned out. Over time, feedback from clients hooked up to our labs and using E1BPC in intermediate syntheses has pointed out the difference that tight purity windows can bring. In practical use, people notice: no sticky residues on glassware, less time wasted in purification, and more predictable conversion rates in secondary reactions. That sort of reliability doesn’t land by accident, but is the upshot of careful engineering and the collective stubbornness of a team that wants things as perfect as possible.
A big part of our production is listening—keeping track of what customers want, and also understanding how their needs shift in practice. There are plenty of piperidine compounds floating around the specialty chemical market, but E1BPC finds its niche with researchers and companies that need predictable, efficient transformations in multi-step syntheses. We built some of our earliest relationships with companies struggling to balance purity against price or workability. Engineers on the line learned early that minor contaminants can gum up reactors and ruin yields, especially when scale moves from flask to drum. It’s the sort of insight gained only after delivering product to the same client every month for several years and seeing what they actually asked for: less flash, more follow-through.
The backbone of E1BPC’s appeal is its proven performance as an intermediate. Typical end-users come from active pharmaceutical ingredient development, contract research, or fine chemical synthesis. They tap into the structure of the molecule, leveraging the benzylpiperidine core for complex target molecules. This isn’t always for flagship molecules people talk about at conferences, but for a steady stream of blocks used in making new drug analogs, molecular probes, and building out compound libraries.
Plenty of our business relationships started with a laboratory-scale sample. Researchers would call after test reactions, usually with questions or wish-lists. We put a lot of stock into those early talks—finding out which solvents play nicely with E1BPC, which bases give a clean product on amidation, and how the molecule acts during complex couplings. Our process has evolved hand-in-hand with these questions: feedback from labs lets us adjust impurity profiles, improve packaging (no more leaking bottles!), and even tweak the way we dry and store product before dispatch. Over time, that collaborative spirit has built trust, and customers stick with us because we respond fast and take their feedback seriously—not out of obligation, but because it saves everyone time and hassle.
The hardest lessons in chemical manufacturing come from mistakes in the plant. We’ve seen it at every stage, from small reactors up to full-scale production. Ethyl 1-Benzylpiperidine-4-Carboxylate rewards careful attention. In the early days, inconsistent crystallization left us with sticky, hard-to-handle product. Shifts in solvent or reaction order sometimes led to small surprises—tiny impurities that seemed harmless at first. As one of our most demanding intermediates, E1BPC forced us to overhaul routine testing. Thin-layer chromatography, HPLC, and direct NMR analysis became standard, not just for finished product, but at checkpoints throughout the process.
Problems got fixed one by one. Leaky joints meant extra maintenance routines. Reagent quality, once thought “good enough,” now gets regular reviews because we learned cheap shortcuts create far worse problems downstream. Every mistake cost us time and money, but far more value came back to us through better yields, smoother processing, and cleaner product. This is how true hands-on knowledge accumulates, not by default, but through sweat and dissatisfaction with “good enough.”
Our line includes closely related piperidine carboxylates. Each brings something different to the table, but E1BPC finds a unique balance between chemical reactivity and practical handling. Where methyl or isopropyl substitutes might bring different rates or byproducts, the ethyl group on E1BPC shapes solubility just enough to grant cleaner separations and less fuss downstream. Cyclizing intermediates or functionalizing on the aromatic ring often call for reliability in the scaffold—one contaminated batch can shift whole project timelines. E1BPC’s purity and reactivity, shaped by our approach, gives a dependable backbone where other esters stumble.
Folks have asked why we don’t just push everything toward higher-throughput materials, or why we bother tuning such a “simple” molecule. The short answer is that not every application tolerates variables. With E1BPC, the ease of workup, answerable impurity checks, and a track record for stability wins out. When we stack it side-by-side with methyl, propyl, or bulkier versions, the scale often tips back in E1BPC’s favor for real-world projects that move out of the test tube and into process development.
Anyone can print off a shiny brochure about correct storage and safe handling, but years on the factory floor have taught us where problems actually crop up. For E1BPC, temperature swings matter. We keep stocks tightly sealed and shaded because air and light create breakdown products you’d never spot on short timelines. Our plant runs regular checks on drum seals, and we cycle out older inventory instead of trying to push expired batches out the door. These judgment calls, not just a checklist, have saved end-users from head-sized headaches. The feedback loop between warehouse and customer service isn’t always pretty, but it keeps us honest and focused.
Our packaging department takes pride in how orders ship out. Too many times in the past, poorly packed materials arrived sticky or lost through broken seals. Now every drum and bottle follows a double-check system, with the same crew following through until the order loads onto the truck. Packing up E1BPC for safe travel and clear labeling matters: it’s not just compliance, but real respect for the people further down the chain who depend on us getting the basics right.
Customers who use E1BPC at scale run into practical hurdles—solubility snags, clogging of process filters, and unexpected color changes under odd processing conditions. Instead of swatting these problems away, we work out fixes. During conversations with plant chemists, we found that tweaking solvent choice or staying within a tight pH band during extractions kept the material flowing smoothly. Each suggestion we make comes straight from in-plant tests, not copied from a text. The cycle—problem, test, solution—keeps our product relevant and practical instead of just another number in a catalog.
Some of the best ideas have come from frustrated line operators. One crew flagged an issue with partial crystallization that almost slipped through packaging. Their observations led us back into the process, adjusting residues, swapping out old piping, and reviewing all the monitoring on the batch tank. That kind of ground-up change delivers real improvements and proves no batch should ship without people checking both paperwork and the product itself.
E1BPC isn’t just another chemical in a long list. Work with research and development teams has helped shape not only our own processes but also the way our clients attack tough projects. Sometimes, pharmaceutical development groups push the molecule into new places, and our flexible approach lets us follow. We’ve collaborated on fine-tuning impurity signatures for regulatory filings, adjusted protocols for green chemistry initiatives, and piloted new packaging formats to cut down on waste. Few end-users stick to one way of using E1BPC, so our technicians regularly chat with end-users about setting up reactions, integrating the product into automation, and scaling up from a few grams to production kilos.
The partnerships that matter most aren’t about volume, but trust and technical back-and-forth. We’ve brought our own failures and breakthroughs to the table, and found that open discussion gets everyone further than hiding behind spec sheets or waiting for problems to blow up. No one on our staff wants to see wasted time or product. Our practical experience carries forward to how we help users solve rotary evaporation issues, rework solvent systems, and troubleshoot analytical methods that sometimes have trouble with the molecule’s aromatic signature.
Market demand for E1BPC moves with trends in specialty medicine and contract synthesis. Some years, pickup jumps because of a clinical trial; other times, new regulatory pressure asks for traceability and tighter specs. Because we control our manufacturing and don’t rely on outside processors, we weather the booms and slumps with more control over batch scheduling and resource management. Our raw material partners—chosen after years of vetting—help us pivot as customer needs change, making sure we can adjust output swiftly without sacrificing reliability.
We noticed early that short-term market thinking leads to supply squeezes and product gaps. Too many times, traders dump stock at the bottom of a demand spike and vanish when things tighten. We’ve built long-term agreements with key accounts, favoring steady collaboration over chasing every order. This approach lets us keep E1BPC available, and it means customers see the same quality and faces over many years, not just a log-in page and an invoice. Stability counts for a lot more in chemicals than flashy marketing or promises of rock-bottom pricing.
Our approach to E1BPC production puts regulatory needs at the front of every decision. Meeting purity standards isn’t about ticking boxes, but about delivering product that stands up to audit, review, and the scrutiny of downstream applications destined for clinical or commercial use. Documentation and traceability are baked into every batch—not because regulators ask, but because our clients demand real transparency. Every incoming shipment, process step, and final test feeds into records we back up and share for peace of mind.
Long-term sustainability questions drive plant upgrades. We've moved to more efficient chemistries that cut down on solvent waste and energy draw. Recycle loops for certain wash streams keep waste under control. These efforts shave off costs and time, but most of all, they put us on a firmer footing as supply chains tighten and regulatory rules shift. Companies who rely on E1BPC to anchor synthetic routes care about more than just today’s pricing; they want partners who will last as long as their projects. Our shift to greener processing and closed-loop controls isn’t a bullet point, but the next sensible step in keeping our operation resilient for the long haul.
Each pass through production adds to our understanding of what E1BPC means—not just as a molecule, but as a touchstone for how our company learns and adapts. Clients often ask about future supply, process tweaks, or what lies ahead for specialty chemicals needed in advanced research. Our experience tells us the only useful promises come from continual testing, straight talk, and a willingness to dig into the details when the unexpected pops up.
As customers demand faster turnaround, tighter specs, and smarter logistics, our operation keeps shifting with them. That agility only holds up because we built a foundation of real-world experience—not theory, but practical work and a willingness to get hands dirty when things don’t run right. E1BPC remains a product we’re proud to make, not only because of its role in the lab but as an example of a hard-won approach to consistent, honest manufacturing.
Behind every drum of E1BPC leaving our loading dock sits a chain of humans doing careful, thoughtful work. Every analyst, maintenance tech, and plant operator puts in long hours to steer a difficult product where it needs to go. Our job isn’t simply to fill orders, but to improve with each batch, meeting challenges straight on, and treating every request as a chance to get better. The ultimate difference between E1BPC and other products comes down to this shared commitment. Over decades in the industry, we’ve learned the best results come from respect for chemistry and for the people depending on it every day.