Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Ethyl 1,3-Dimethylpyrazole-5-Carboxylate

    • Product Name Ethyl 1,3-Dimethylpyrazole-5-Carboxylate
    • Alias EDPC
    • Einecs 416-610-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    694595

    Product Name Ethyl 1,3-Dimethylpyrazole-5-Carboxylate
    Cas Number 4269-16-9
    Molecular Formula C8H12N2O2
    Molecular Weight 168.19 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 130-132°C at 10 mmHg
    Density 1.06 g/cm3
    Purity Typically ≥98%
    Solubility Insoluble in water; soluble in organic solvents
    Refractive Index 1.505 (approx.)
    Smiles CCOC(=O)C1=CN(N=C1C)C
    Storage Temperature Store at 2-8°C

    As an accredited Ethyl 1,3-Dimethylpyrazole-5-Carboxylate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100-gram amber glass bottle with a tight screw cap, labeled "Ethyl 1,3-Dimethylpyrazole-5-Carboxylate," hazard and handling instructions included.
    Shipping Ethyl 1,3-Dimethylpyrazole-5-Carboxylate should be shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. Use robust packaging to prevent leaks or damage. Transport in compliance with local, national, and international chemical regulations, including labeling and documentation requirements. Avoid extreme temperatures and ensure secure handling during transit.
    Storage Store Ethyl 1,3-Dimethylpyrazole-5-Carboxylate in a tightly sealed container, in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizing agents. Protect from heat, moisture, and direct sunlight. Ensure proper chemical labeling and access for authorized personnel only. Follow all relevant safety data sheet (SDS) guidelines for handling and storage.
    Application of Ethyl 1,3-Dimethylpyrazole-5-Carboxylate

    Applications of Ethyl 1,3-Dimethylpyrazole-5-Carboxylate in Industrial Manufacturing

    Ethyl 1,3-Dimethylpyrazole-5-Carboxylate supports precise performance improvements and regulatory control across several advanced chemical manufacturing segments. Our facility supplies this material in production-scale quantities to customers with tailored technical and compliance requirements.

    1. Synthesis of Crop Protection Agents (Pesticide Intermediates)

    Major agrochemical producers use this compound as a building block in the multi-step synthesis of modern herbicide and fungicide actives. Its structure enables precise control over substitution patterns in pyrazole-derived agrochemical molecules. The compound is introduced during early-stage synthesis, often forming part of a condensation or alkylation system. Its use affects the final selectivity profile, ensuring target-specific crop protection. Scale-up operations require careful refinement to maintain purity and batch consistency, directly impacting efficacy and regulatory acceptance in agriculture markets.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • FAO/WHO Code of Conduct on Pesticide Management
    • REACH Registration (EU)
    • China Ministry of Agriculture Pesticide Registration

    Typical usage ratio

    • 5–12% in intermediate synthesis steps, with adjustment based on target molecule and process yield targets

    Downstream process integration

    • Added during condensation or cyclization after initial pyrazole ring formulation
    • Follows controlled addition under inert atmosphere for side-chain introduction

    Final product types

    • Selective herbicide actives
    • Systemic fungicide actives
    • Insecticide intermediates containing pyrazole systems
    • Pre-mix technical concentrates

    2. Pharmaceutical Intermediate for Pyrazole-Based APIs

    The compound serves as a core intermediate in manufacturing several active pharmaceutical ingredients, especially modern pyrazole derivatives used in anti-inflammatory and anticancer drugs. Pharmaceutical synthesis requires strict control of impurity profiles and batch reproducibility, which this material supports due to its well-defined purity and reactivity. It is typically used in condensation reactions during mid-synthesis, forming key frameworks that undergo further functionalization. Downstream, this enables scale production of regulated APIs suitable for regulated global markets, including those demanding ICH Q7 compliance.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practices for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211 cGMP
    • EU GMP Guidelines (EudraLex Volume 4)
    • Ph. Eur., USP, and JP relevant monographs for APIs

    Typical usage ratio

    • 3–10%, calculated per step and subject to change with stoichiometry and reaction optimization

    Downstream process integration

    • Charged post-initial active ring formation
    • Used in batch or semi-continuous processes under anhydrous conditions, supporting further functionalization or protection steps

    Final product types

    • Non-steroidal anti-inflammatory drug (NSAID) APIs
    • Antineoplastic pharmaceutical actives
    • Pyrazole-based CNS drugs
    • Bulk intermediates for contract manufacturing organizations

    3. Synthesis of Specialty Chemical Additives for Polymers

    Polymer manufacturers integrate this pyrazole carboxylate ester into formulations as a precursor for specialty UV-absorbers and stabilizers. Its chemical structure supports the production of functionalized additives that provide enhanced photo-stability in engineering plastics, fibers, and coatings. The ester undergoes further functionalization or hydrolysis, depending on the additive's design. Reaction steps require precise stoichiometric control and real-time analytical monitoring to maintain required performance specifications for high-value polymer applications, including automotive and electronics.

    Industry compliance standards

    • ISO 14001 Environmental Management Systems
    • EN 71-3 Safety of Toys (Heavy Metals in Plastics)
    • RoHS Directive 2011/65/EU (for polymers used in electronics)
    • Global Automotive Declarable Substance List (GADSL)

    Typical usage ratio

    • 0.2–3% in additive precursor formulations, modulated to meet UV-stability and migration resistance targets

    Downstream process integration

    • Introduced during additive precursor synthesis, typically at the esterification or amidation stage
    • May undergo purification before compounding with polymer resins

    Final product types

    • Hindered amine light stabilizers (HALS)
    • UV-absorbers for automotive coatings
    • Polymer additives for consumer electronics enclosures
    • Special effect masterbatches

    4. Development of Advanced Fine Chemical Intermediates

    Producers of advanced fine chemicals utilize this carboxylate ester to introduce specific pyrazole motifs within molecules destined for specialty dyes, imaging chemicals, and custom organic synthesis pathways. The material’s consistent behavior under varied reaction conditions allows for insertion as a key intermediate in high purity or chiral synthesis routes. Its performance in controlled esterification or substitution reactions enables the precise tuning of functional group orientation, a requirement in electronic chemical and specialty pigment production.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • Responsible Care chemical management protocol
    • Japanese Chemical Substance Control Law (CSCL)
    • REACH Annex II (Safety Data Sheet requirements)

    Typical usage ratio

    • Variable: 2–7% by molar ratio, adjusted by reaction conversion requirements and end-use target molecule complexity

    Downstream process integration

    • Introduced at select condensation or coupling steps in fine chemical synthesis
    • Processed under nitrogen or controlled temperature profiling

    Final product types

    • Specialty fluorescent dyes
    • Photographic imaging chemicals
    • Custom organic synthesis building blocks
    • Organic electronic intermediate chemicals
    Free Quote

    Competitive Ethyl 1,3-Dimethylpyrazole-5-Carboxylate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Ethyl 1,3-Dimethylpyrazole-5-Carboxylate: Manufacturing Perspective on Value and Usage

    Direct from the Plant Floor: Our Take on Ethyl 1,3-Dimethylpyrazole-5-Carboxylate

    Daily work in the chemical industry grants us a close-up understanding of substances like Ethyl 1,3-Dimethylpyrazole-5-Carboxylate. As manufacturing chemists, we see compounds not as catalog items but as solutions that drive real results for formulators, researchers, and production teams. In our facilities, every batch of this material reflects both routine precision and trial-by-fire adaptation. This makes it possible to maintain consistent quality, which users depend on in their finished products.

    Unpacking Model and Specifications: Insights from Production

    In our plant, Ethyl 1,3-Dimethylpyrazole-5-Carboxylate most often leaves the warehouse as a pure, fine, white crystalline powder. Each production lot passes through a series of quality controls, including High Performance Liquid Chromatography, melting point analysis, and checks for moisture content. Typical purity exceeds 98.5%, based on our in-house data for routinely analyzed lots over several years of scaled production.

    During daily operations, batch sizes range from kilograms for custom R&D projects up to metric tons for regular commercial orders. Some users request additional sieving or drying, which means product logistics start at the reactor and carry through to final shipping. We keep the supply chain simple: material is packaged in lined polyethylene drums or fiber cartons, sealed against air and moisture, with units ranging from 10 kg to 40 kg per container. Custom packaging is available, not for branding, but because minimizing exposure to humidity and air during transit makes storage easier at the user’s facility.

    Weighing Usage: Application Experience Informs Choices

    Working daily with clients in agrochemical synthesis, polymer chemistry, and high-value organic intermediates, the demand for high-purity Ethyl 1,3-Dimethylpyrazole-5-Carboxylate stands out. Our technical teams and process engineers find this pyrazole derivative playing key roles as a building block in the stepwise synthesis of crop protection agents. In herbicide or fungicide production, the sterically hindered pyrazole ring combines chemical stability with a functional ethoxycarbonyl group, ideal for downstream modification. Our feedback from process chemists confirms that conversion routes involving this ester consistently yield products with improved shelf life and environmental stability.

    Away from the field of crop science, the compound’s utility in polymers comes to the fore due to its ring structure and substitution pattern. In our own experience, polymer additive formulators approach us not only to procure material but to discuss the interplay between pyrazole functionality and polymer backbone chemistry. Ethyl 1,3-Dimethylpyrazole-5-Carboxylate resists unwanted side reactions, allowing additive chemists to harness its electron distribution for more precise tuning of physical properties, such as UV resistance or cross-link density in specialty coatings.

    Comparing to Similar Compounds: Practical Differences, Not Just Numbers

    If you have ever stood at a loading dock beside a shipment of Ethyl 1,3-Dimethylpyrazole-5-Carboxylate, chances are you have compared it directly to other substituted pyrazole esters or amides. One of the practical points we see is the impact of methyl substitution at the 1 and 3 positions. This specific alkylation pattern reduces unwanted byproduct formation during condensation reactions. Feedback from formulation chemists supports this: batches that use structurally similar, but less methylated pyrazoles, frequently show lower target yields or require extra purification steps.

    Ethyl 1,3-Dimethylpyrazole-5-Carboxylate’s ester group, compared with amide or acid analogues, strikes a real-world balance. We have observed less sensitivity to hydrolysis in normal storage and processing, even before the product line leaves our plant. Commercial users echo this, reporting reliable performance in both organic and water-based systems, which is not always the case with comparable acid or amide compounds.

    Over the years, research chemists have brought us a rotating cast of “alternatives” in pursuit of cost savings or novel features. Still, process data from multiple campaigns show that our product’s synthesis handles scale-up more cleanly. Fouling remains lower in reactors, filtration steps run faster, and downstream work-up enjoys greater reproducibility. These operational advantages flow from years of method refinement and direct feedback from downstream facilities.

    Addressing Common Issues: Stability, Storage, Safety—Lessons from the Field

    We frequently hear concerns about storage or shelf life, especially for shipments crossing humid regions or exposed to temperature cycles. In our own warehouses, we store Ethyl 1,3-Dimethylpyrazole-5-Carboxylate at ambient temperature, out of direct sunlight, with a focus on dry conditions. Moisture presents the main risk; hydrolysis under extended exposure is minimal, based on our long-term stability data gathered from stockroom sampling over several seasons. Nonetheless, we recommend that partners reseal containers promptly and monitor local humidity when material is decanted into smaller vessels.

    Reactivity with common solvents or packaging linings does not create issues in our production environment or the broader supply chain. No significant pressure build-up or residue has ever resulted from extended storage in industry-standard PE-lined containers under factory conditions. Safety-wise, the exposure risks rate as moderate, making routine goggles and gloves sufficient during normal handling. Over the years, we have worked with workplace safety teams and found that routine operational protocols suffice; no specific engineering controls or PPE beyond normal organic chemical handling has been requested or required.

    Factual Background: Decades of Manufacturing and Performance Data

    Our production team has synthesized Ethyl 1,3-Dimethylpyrazole-5-Carboxylate for more than a decade. From early pilot trials in modest glassware to current commercial campaigns in jacketed vessels, the evolution of this product line springs from daily plant floor problem-solving. Scaling up brought unexpected challenges—new solvent systems tested heat transfer coefficients, and minor changes in water content altered batch yields. Through mixed-instrument analytics and bench chemistry trialing, we have locked in process steps that deliver reproducible results at the ton scale.

    Routine product characterization involves not just purity assessment by chromatography and NMR, but also end-use feedback from formulating chemists and manufacturers at the customer’s site. Several years ago, a major partner in the agrochemical sector challenged us to optimize for a narrower melting range due to downstream formulation requirements. Joint work between in-house process engineers and client teams resulted in procedural tweaks: tighter temperature control during esterification, tailored vacuum drying cycles, and upgraded moisture sensors in packaging lines. This kind of feedback loop produces a product with predictable performance in practical use, not just on paper.

    Our technical support and R&D groups regularly collect shelf-life data on bulk and repacked materials, monitoring not only product integrity but impact from accidental exposure. More than one batch has been rescued or reprocessed following unexpected warehouse mishaps—overturned drums, misrouted shipments, or local power failures. We track how such incidents affect purity, yield, and usability so our clients have the real story on stability and resilience outside textbook conditions.

    Meeting Large-Scale and Specialist Needs Alike

    In the early years, customers ordered by the kilogram. Today, new synthesis routes in agricultural chemistry, and emerging uses in specialty polymers, have pushed demand into the metric ton range. Production managers and logistics staff have learned that scale comes with new problems: batch-to-batch consistency matters more to continuous users, and even slight changes in physical form can disrupt automated handling downstream. Our plant operators adapted by improving milling and sieving processes. At the same time, our technical staff work one-on-one with some formulators to identify physical characteristics that improve process flow, such as tapping density and particle size distribution.

    Some clients operate high-throughput automated systems, which require material with uniform flow, reproducible particle size, and dust minimization. For others, in bespoke lab synthesis, small lots with high purity and an extended certificate of analysis make the difference. We learned by experience how to scale down or ramp up based on what real customers depend on, and production methods evolved to deliver what each new campaign demands.

    Working with Partners: Real Conversations Shape Real Solutions

    Our technical and sales teams work hand-in-hand with procurement managers, R&D chemists, and operations supervisors across the globe. We get regular visits from partners developing new actives or seeking alternatives to restricted substances. One of the distinct advantages for users is access to plant chemists and process engineers handling scale-up questions in real time. There is no sales barrier between the warehouse and the lab: direct feedback leads to improvements in product cleansing, drying, and analytical reporting.

    Many times, challenges emerge mid-run. A client scaling up a new fungicide might notice a trace impurity that did not appear at bench scale. Through regular data sharing, root cause analyses, and, in some cases, on-site consultation or joint lab work, procedural modifications get integrated. Years spent collaborating with formulators outside our own gates have shaped the current specifications and performance attributes industry users now take for granted.

    Potential Solutions to Industry Challenges

    Some clients, especially those in regions with intense climatic swings or restricted local storage, have asked for more robust packaging and longer shelf-life guarantees. Our solution draws from both process control and packaging innovation. Desiccant packs, vacuum sealing, and once-through liner systems—each emerged from local user feedback. We also rolled out batch-level traceability, allowing downstream labs to pull up detailed processing, analytical, and shipping histories for every lot delivered.

    Intellectual property is another regular topic. Several teams approach us seeking variants, derivatives, or custom synthesis routes. Through private-label partnerships and nondisclosure arrangements, we have developed new analogues based on Ethyl 1,3-Dimethylpyrazole-5-Carboxylate as a backbone. These efforts resulted from market signals, not just exploratory R&D: partnership with end users accelerates new product lines in a way closed labs rarely pull off.

    Price instability and supply chain interruptions occasionally ripple across the specialty chemical sector. To buffer risk for long-term partners and large-volume users, we maintain strategic feedstock inventories and dual-certified processing streams. Localizing raw material sourcing and building in process redundancy have allowed us to keep supplying even when upstream incidents hit the broader market.

    Education and regulatory harmonization also come up, particularly in fields such as agricultural chemistry. As manufacturers, we carry out limited but targeted outreach: offering technical seminars for client chemists, regulatory briefings for compliance teams, and hands-on site audits when local requirements shift. This means our knowledge pool grows with end-user experience, and product documentation evolves to address new directives from oversight bodies.

    Quality Culture: Beyond Specification Sheets

    Production culture inside a manufacturing plant never stands still. No amount of documentation substitutes for institutional memory—the lessons learned from a batch that crystallized too soon, a shipment delayed by customs, or a new certification rule changing last-minute requirements. Our personnel receive ongoing training not just in process chemistry, but also in root cause analysis, customer communication, and regulatory awareness. Direct conversations between back-office staff, production troubleshooters, and shipping clerks capture issues long before they become sales detractions.

    Analytical capabilities grow in parallel with production scale. Newly installed chromatography and spectroscopy instrumentation tap into deeper levels of product characterization, while data-sharing agreements with key customers ensure analytical findings broadcast quickly to both parties. This approach aligns with tough standards set by regulatory audits and industry watch groups, deepening our credibility as not just suppliers, but as long-term partners.

    Commitment to Transparency and Real-World Improvement

    Experience with Ethyl 1,3-Dimethylpyrazole-5-Carboxylate stretches across the value chain. Our own engineers test material in applications popular among end users, so every improvement feeds directly into updated processing, analytical, or packaging protocols. Commercial realities—unexpected weather, evolving regulations, novel uses—constantly put claims to the test. Improvements to product handling or analytical quality do not appear just in laboratory notebooks but in the practical experience of the warehouse, the customs agent, and the user pouring that next drum into their process line.

    Genuine product quality takes shape through dialogue. Lessons from a mispacked drum or a failed reaction translate into changes at the batch line, the stockroom, and the end of the delivery truck. As a manufacturing group, these cycles of trial, error, and adaptation provide our main advantage. This is how Ethyl 1,3-Dimethylpyrazole-5-Carboxylate has secured a place among the most reliable building blocks across our clients’ operations in crop science, polymer engineering, and specialty organic synthesis. Our product stories grow out of real mixes, real environments, and dependable people making sure each batch will do what customers actually need—not just what the spec sheet claims.