Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Eprazinone

    • Product Name Eprazinone
    • Alias Praxin
    • Einecs 245-617-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    735274

    Name Eprazinone
    Cas Number 493-41-6
    Molecular Formula C20H25ClN2O
    Molecular Weight 344.88 g/mol
    Appearance White crystalline powder
    Solubility Slightly soluble in water
    Drug Class Expectorant
    Mechanism Of Action Increases bronchial secretion and reduces mucus viscosity
    Route Of Administration Oral
    Atc Code R05CB09
    Indication Relief of cough and improvement of bronchial mucus clearance
    Storage Conditions Store at room temperature, away from moisture and light

    As an accredited Eprazinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Eprazinone is packaged in a 100-gram amber glass bottle with a secure screw cap, labeled with hazard and storage instructions.
    Shipping Eprazinone should be shipped in tightly sealed containers, away from direct sunlight, moisture, and incompatible substances. Use appropriate hazard labeling and follow regional regulations for chemical transport. During transit, maintain secure packaging to prevent leaks or spills, and provide safety documentation and emergency contact information in compliance with shipping regulations.
    Storage Eprazinone should be stored in a tightly sealed container, away from light and moisture, at room temperature (15–30°C). It must be kept in a cool, dry place, away from incompatible substances such as strong oxidizers. Ensure the storage area is well-ventilated, and restrict access to qualified personnel. Proper labeling and handling in accordance with standard chemical safety protocols are essential.
    Application of Eprazinone

    Applications of Eprazinone in Industrial Manufacturing

    Eprazinone is an active pharmaceutical raw material utilized in specific pharmaceutical preparations and advanced API (Active Pharmaceutical Ingredient) synthesis. Our factory supplies Eprazinone directly to downstream manufacturers with stable quality control for regulated industry needs. Below are verified industrial applications for Eprazinone based on contemporary manufacturing practices.

    1. Mucolytic Agent Formulation for Oral Syrups

    Major pharmaceutical producers formulate Eprazinone into mucolytic syrups to support respiratory tract health. Precise blending occurs under GMP-controlled workflows to meet prescription medication batch requirements. Process engineers weigh Eprazinone based on final API percentage, mixing it with excipients such as flavoring, sweetening, and preservation agents. The finished product undergoes quality assurance and stability testing before bottling and secondary packaging for commercial distribution to pharmacies and clinics.

    Industry compliance standards

    • Chinese Pharmacopoeia (ChP)
    • European Pharmacopoeia (Ph. Eur.)
    • Good Manufacturing Practice (GMP) for Pharmaceuticals
    • Drug Master File (DMF) registration requirements

    Typical usage ratio

    • 1.0–2.0% by weight as active API in oral syrup preparations
    • Adjust based on syrup base composition and targeted therapeutic strength

    Downstream process integration

    • Dissolve Eprazinone in pre-mixed syrup base under controlled temperature
    • Inline blending with stabilizers and sweeteners
    • Homogenization prior to filtration and bottling

    Final product types

    • Mucolytic oral syrup for adult and pediatric use
    • Prescription respiratory syrup
    • Hospital-use syrup-based expectorant

    2. Solid Oral Tablet Manufacturing

    Tablet manufacturers incorporate Eprazinone into granulation and compression processes for respiratory indications. Material engineers ensure microcrystalline Eprazinone disperses evenly with binders and fillers. Blend uniformity is measured batch-wise before direct compression. Control laboratories frequently verify API content throughout tablet cores. After pressing and drying, operators apply film coatings to improve swallowing and dose stability. Packaging lines count and seal finished tablets in blisters or bottles according to regulatory batch tracking systems.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • WHO GMP Guidelines
    • Pharmacopeial monographs per importing region (e.g., US Pharmacopeia, EU GMP)
    • Accelerated stability trial protocols

    Typical usage ratio

    • 5–50 mg per tablet, adjusted according to prescription dosage
    • Pre-mix at 3–7% API ratio by compound blend for dry granulation

    Downstream process integration

    • Integrated API addition in blending vessels
    • Wet or dry granulation prior to tablet compression
    • Automated dosage weighting and machine pressing

    Final product types

    • Prescription and OTC respiratory tablets
    • Generic mucolytic tablets
    • Combination therapy tablets (with decongestants)

    3. Active Ingredient for Cough Lozenges

    Lozenge and hard candy medicine producers use Eprazinone for directed release in oral cavity formulations. Manufacturing teams accurately dissolve measured quantities with pharmaceutical-grade sugars and binding agents using batch kettles. Homogenizers disperse the active across the substrate for even taste and mouth-feel. The liquefied mixture is molded, thermally set, and run through quality analysis for uniform API content. Automated wrapping and lot traceability further ensure regulatory conformity and commercial presentation.

    Industry compliance standards

    • Food and Drug Administration (FDA) cGMP for medicine-candy hybrids
    • Pharmaceutical Inspection Co-operation Scheme (PIC/S) standards
    • ISO 9001 Quality Management System certification
    • Applicable national drug regulatory approvals

    Typical usage ratio

    • 1–4 mg Eprazinone per lozenge, based on intended effect
    • Typically, 0.5–1.2% loading in lozenge mass

    Downstream process integration

    • Inline dosing of pure API during candy mass cooking
    • Mixing and uniform distribution before molding and cooling
    • Immediate transition to packaging line post-cooling

    Final product types

    • Medicinal cough relief lozenges
    • Mucolytic drops for pharmacy sale
    • Multi-active cold symptom candies

    4. API Intermediate in Contract Pharmaceutical Synthesis

    Leading CMO (Contract Manufacturing Organization) and CDMO (Contract Development Manufacturing Organization) facilities source Eprazinone as a controlled intermediate to develop complex respiratory medications. Chemistry teams handle the compound under validated process controls, following strict segregation and containment procedures to ensure API purity throughout downstream reactions. Eprazinone undergoes transformation steps such as esterification, salt formation, or micronization before integration with other actives. Production managers continuously monitor traceability and maintain full documentation for regulatory agencies and customer audits.

    Industry compliance standards

    • ICH Q11 Development and Manufacture of Drug Substances
    • China FDA APIs and Intermediates Registration
    • European Medicines Agency (EMA) GMP for Intermediates
    • REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) compliance where required

    Typical usage ratio

    • Up to 100% as neat API intermediate for multi-step synthesis
    • Batch-wise transfer based on targeted output for downstream modification

    Downstream process integration

    • Introduced to chemical reactors at specific synthesis steps
    • Processed under nitrogen inert atmosphere to prevent degradation
    • Transferred to formulation departments after conversion or purification

    Final product types

    • Advanced mucolytic APIs for branded pharmaceuticals
    • Custom-labeled finished dosage forms for major pharma brands
    • Co-crystallized respiratory actives for global export
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    Certification & Compliance
    More Introduction

    Eprazinone: Building Relief through Reliable Chemistry

    Bringing Eprazinone to Life in Our Facility

    Eprazinone has been a stable presence in our manufacturing lineup for over a decade. The mainstay model we focus on carries a chemical identity recognized globally: 1-(2-ethylphenyl)-3-(1-piperidinyl)-1-propanone hydrochloride. The drive to consistently produce pure, dependable Eprazinone comes straight from our commitment to both end-users and our partners in the pharmaceutical world. Each batch originates from raw materials we know inside and out. Operations involve a multi-step synthetic route streamlined and improved through both experience and investment in up-to-date process controls. The chemistry is tough, but it puts us in direct contact with each molecule from the first drop of solvent to the final, packaged powder.

    Our facility doesn’t run in a vacuum. With every reaction, we balance chemist expertise, machine reliability, and market needs. Over the years, we’ve adjusted reaction conditions to keep impurities below threshold levels recognized by global pharmacopoeias. We don’t run these processes just because regulations demand it; we know that strict attention to byproduct control leads to a smoother flowing supply chain and greater confidence among formulation scientists. Old-school methods have their place, but newer chromatographic checks and high-resolution NMR have kept our product out of the murky waters you sometimes get with corner-cutting labs. Every time we commit material to a batch, the consequences for downstream partners—from capsule fillers to doctors—remind us to stick to discipline and accountability.

    Specifications That Matter in Real-World Application

    The technical sheet for Eprazinone doesn’t tell the whole story. Sure, a white or nearly white crystalline powder with a melting range between 202°C and 206°C might sound routine. In practical terms, these tiny details translate to reduced fuss during product blending and tableting. Particle size distribution and loss on drying minimums might go unnoticed for those who only see the final pill—but we know from years of experience that even slight outliers can jam up granulation steps, clog screens, or generate unplanned downtime in plant runs. That’s why the numbers have teeth and get checked at every step.

    Every chemist or pharmacist who’s handled Eprazinone knows the kind of residue or stickiness that comes from moisture or solvent lingering in the compound. That’s more than a spec box to tick. It impacts shelf-life stability and creates headaches with weight variation in small-batch or industrial-scale production. Through process tweaks and steady investment in vacuum drying and filtration, we’ve knocked our residual solvents to much stricter levels than required. Fewer surprises in the drum translate to less troubleshooting on the customer’s end. For color, purity, residue content, and assay, we meet standards laid down by international pharmacopeias—highlighting hydrogenation completeness and handling even those trace process-related impurities that sometimes haunt less experienced outfits.

    How Eprazinone Finds Its Place

    The bulk of bulk Eprazinone moves out to build cough and respiratory medications, especially where bronchial secretolytic effects are sought. Its role as a mucolytic agent—thinning and loosening mucus for easier expulsion—makes it a staple in expectorants for adults and children alike. On factory tours, we’ve witnessed our own Eprazinone blended seamlessly into high-speed pharmaceutical operations where it needs to integrate with excipients like lactose, mannitol, or microcrystalline cellulose. Every operator, packaging supervisor, and formulator on the other side of that transaction expects a product that will behave without causing unexpected physical or chemical surprises.

    A key reason physicians and pharmacists keep coming back to products made with our Eprazinone lies in its reliability for patient response. Clinical demand ebbs and flows, but once a product makes its mark as both effective and consistent, it tends to become entrenched: pharmaceutical supply chains don’t gamble with respiratory relief. People managing seasonal spikes in cough due to flu or allergies require a steady stream of this compound. Our consistency doesn’t happen by accident, but by running each batch through validated equipment and analytical setups we’ve designed ourselves after untangling batch-production problems over the years.

    Setting Eprazinone Apart from Similar Offerings

    A laboratory can create plenty of molecules with similar effects—Ambroxol, Bromhexine, and Carbocysteine all share mucolytic properties with Eprazinone. The real world draws sharper lines. We’ve seen Eprazinone chosen time and again not only because of its pharmacological effect but because the handling qualities save our customers headache and cost. Some alternatives bring stability challenges: they react too readily with moisture, degrade under heat, or demand expensive excipients just to maintain flowability in compacting equipment. Others create regulatory hurdles with higher trace impurities or byproducts. Many buyers start with price comparisons but come back to Eprazinone when throughput or product quality becomes the primary concern.

    We know some companies use generic suppliers, purchasing based on spot market fluctuations. In the long run, this approach turns risky, especially when end-use regulatory filings require transparent and clean supply histories. Our ability to trace each kilogram from incoming material to final shipment lets pharmaceutical partners lock in peace of mind during audits and product recalls. Generic producers might chase the lowest cost with less traceable sources or inconsistent quality. We have chosen to compete not just on price alone, but on a combination of traceability, batch consistency, and solid documentation.

    Troubleshooting Real-World Challenges

    Every manufacturer faces days when things don’t go as planned. Humidity spikes, a slip in filtration parameters, or a new lot of raw material behaving differently—few operations run forever problem-free. We’ve faced these hiccups over and over, and learned not to hide behind generic excuses. The difference comes down to anticipating pattern changes before a glitch shows up. For Eprazinone, we dedicate regular resources to real-time monitoring and rapid-response teams. Whenever a shift manager notices yield changes or deviation in color or moisture, corrective action happens not days, but minutes later.

    Take the case when a supplier’s solvent quality changed, throwing off the crystalline habit of the product. It created flow issues for one major customer’s tableting process. Our technical team spent a hectic weekend dissecting and tracing the source, then adapted our process steps with revised purification and a closer supplier relationship. The customer’s line got running in just a few days. Such troubleshooting builds trust in both directions. We can’t eliminate all risk from the supply chain, but our operations have shaped around making issues rarer and less lasting compared with less experienced or more price-driven players.

    Value Built on Decades of Hands-On Experience

    We’ve learned that every product batch carries a piece of our reputation—far beyond what standard certificates of analysis can represent. Each season brings new challenges: shifting regulations, tightening impurity limits, higher demands for traceable raw materials, diverse customer requests for packaging or delivery. Meeting these demands means more than ticking compliance boxes. Our team puts real-world experience into every phase, preferring prevention to emergency troubleshooting. Open communication with production workers, quality analysts, and end-users keeps our process evolving.

    Eprazinone stands as an example of our approach. Process economics matter, but they never overrule safety, precision, or documentation. When market shifts push raw material prices up, our process engineering group hunts for savings by optimizing yields and recycling solvents, not by cutting corners or compromising on documentation. We review both upstream and downstream process impacts, making sure our changes don’t ripple out to create new issues for partner plants. Decades of batch records, test results, and customer feedback inform every modification. The learning cycle tightens between actual plant experience and analytical review.

    Responding to New Demands and Market Trends

    Demand for Eprazinone keeps shifting based on both regional health trends and regulatory changes. Respiratory illness outbreaks can drive sudden surges. At times, new competition floods the market with low-cost, poorly documented material, challenging our customers to distinguish quality beyond just paperwork. We have lived through both booms and busts; this cycle never ends. Our solution has always involved transparency and flexibility: scaling up production without letting quality slip, working closely with logistics teams to manage inventory, and being open about production capabilities and constraints.

    Our development team listens to both formulators and procurement teams at partner companies, noting requests for finer control over particle size, alternative package sizes, or documentation for new regulatory filings. We invest in new drying and milling equipment as needs shift. When respiratory pharmaceutical firms started demanding lower dust formulations to minimize workplace exposure, we responded with process tweaks and new containment technologies. This nimbleness sets apart longtime manufacturers from transient market entrants.

    Document Control and Traceability as Cornerstones

    Every shipment of Eprazinone from our plant leaves with a paper trail hundreds of pages deep. Origin of raw materials, analytical test results, checks against reference standards, operator shift logs, and environmental monitoring records all play roles in meeting both regulatory and audit pressures. We aren’t content with just meeting the minimum. Over the years, we have adopted digital batch recording and cross-linked documentation software. This reduces chances for errors and makes access for partner audits quicker and more clear.

    With every process upset, recall, or market inspection, the value of real documentation gets reinforced. Large buyers often send QA teams to walk through our plant, cross-referencing records to samples. They usually spot information that never makes it onto typical data sheets: operator notes on minor process tweaks, raw data printouts, stability trend charts. Our philosophy is that good documentation prevents mistakes getting repeated and strengthens the relationship with those who put faith in what we produce.

    Learning from Both Mistakes and Triumphs

    Manufacturing demands humility. A batch might look perfect on paper, clear the first few checks, then underperform after transport or under new formulation conditions. Early on, we sometimes chalked these surprises up to luck or external factors. Over time, pattern recognition and deeper troubleshooting became vital tools. We track every outlier, consult both production staff and analytic chemists, and rework process parameters. Each improved batch benefits from hard-earned lessons—an experience that new market entrants often lack.

    On the brighter side, solving a persistent problem feels better than just passing another regulatory inspection. Watching our Eprazinone transition smoothly through customer operations and deliver outcomes to end-users keeps the team motivated. We take feedback through regular field visits, looking for unfiltered insights from the people filling capsules, shipping bottles, or managing hospital pharmacies. Good news travels too: repeat orders, customer recommendations, and market reputation emerge from steady attention to detail, not overnight marketing pushes.

    The Future of Eprazinone in the Pharma Landscape

    Regulations evolve, and patient needs change. As more health authorities worldwide tighten impurity requirements or push for better documentation, years of accumulated analytical data and process experience become critical assets. Our teams prepare not just for the next compliance deadline but for shifts in end-user preferences. Investments in purification, digital monitoring, and resilient supply chain partnerships help protect everyone downstream from last-minute shortages or regulatory headaches.

    Eprazinone’s future, at least from our vantage point, will depend on how well it can be integrated into safer, smarter, more patient-focused treatments. We keep an eye on trends in combination therapy, pediatric formulations, and applications in resistant patient populations. Engaged customers reward those of us who think past today’s order book and anticipate tomorrow’s technical or quality concern.

    Why Long-Term Relationships Matter

    After decades in this sector, we know that doing business isn’t just a transaction. Large pharmaceutical groups, growing generics makers, and small compounders look not just for cost or paperwork compliance. What keeps the relationships alive is the technical support during formulation, frank discussions when out-of-spec issues arise, and ongoing improvement based on detailed feedback. Some have been with us since the beginning, relying on our manufacturing consistency through both stable and turbulent times.

    New customers often come with past frustrations—failed validation batches from inconsistent suppliers, regulatory setbacks, or reliability issues in material deliveries. Our approach is to listen, check, and respond with steady quality. Price matters, but dependability defines who sticks around. By knowing every stage of the Eprazinone production chain, we build an offer that holds up under the toughest audit, the busiest production season, or the shortest lead time. That’s how reputation forms: slow, careful, and earned daily by hands-on manufacturing teams.

    Summary: The Eprazinone Commitment

    Eprazinone isn’t just a line on our product list. It reflects a philosophy rooted in hands-on chemical production, accountable documentation, and open, patient-focused partnerships. From process design to technical support after delivery, our teams commit to steady quality, practical feedback, and problem-solving in real time. In a chemical market filled with shortcuts, we hold onto experience, learn from both trouble and success, and keep investing in both people and process improvements. That’s the kind of difference our Eprazinone delivers—not just for us, but for everyone counting on a product that lives up to its name batch after batch.