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Epiandrosterone Acetate

    • Product Name Epiandrosterone Acetate
    • Alias 3β-acetoxy-5α-androstan-17-one
    • Einecs 208-465-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    371766

    Chemical Name Epiandrosterone Acetate
    Cas Number 853-23-6
    Molecular Formula C21H32O3
    Molecular Weight 332.48 g/mol
    Appearance White crystalline powder
    Melting Point 162-164°C
    Solubility Soluble in chloroform and methanol
    Storage Conditions Store at 2-8°C, dry place
    Pubchem Id 102168
    Synonyms 3β-Hydroxy-5α-androstan-17-one 3-acetate
    Stability Stable under recommended conditions
    Inchi Key VKZLSFLKQHXOIC-UYSAQIBZSA-N
    Usage For research and laboratory use only

    As an accredited Epiandrosterone Acetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Epiandrosterone Acetate, 100g: Sealed white HDPE bottle with tamper-evident cap, labeled with product name, batch number, and safety information.
    Shipping Epiandrosterone Acetate is shipped in secure, leak-proof containers to ensure stability and safety during transit. Packages comply with all relevant regulations for chemical handling and labeling. Temperature control and protective packaging are used as needed to prevent contamination or degradation, with documentation provided for traceability and safe receipt.
    Storage Epiandrosterone Acetate should be stored in a tightly closed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, ideally at 2–8°C (refrigerated) unless otherwise specified by the manufacturer. Ensure storage is away from incompatible substances and only accessible to trained personnel. Properly label containers and follow all relevant safety and handling guidelines.
    Application of Epiandrosterone Acetate

    Applications of Epiandrosterone Acetate in Industrial Manufacturing

    As a direct manufacturer of epiandrosterone acetate, we supply advanced intermediates to regulated sectors that require stringent quality, traceability, and production consistency. Below, we outline key industrial application scenarios, focusing on real downstream use cases where our material supports precise formulation standards, integrates smoothly into established workflows, and delivers end products that meet international compliance requirements.

    1. Pharmaceutical Steroid Hormone Synthesis

    Pharmaceutical companies use epiandrosterone acetate as an essential intermediate for synthesizing several steroid hormone derivatives, especially for formulations targeting androgen regulation and related therapies. Compliance with pharmacopeial standards and robust GMP processes remains critical throughout the multi-step chemical conversion and purification stages. The acetate ester enters semi-synthesis routes after initial deacetylation or functionalization, ensuring batch-to-batch consistency for downstream chemical transformations.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP, ICH Q7) for Active Pharmaceutical Ingredients
    • United States Pharmacopeia (USP) / European Pharmacopoeia (Ph. Eur.) monographs referencing intermediates and associated APIs
    • FDA 21 CFR Part 210/211 - Drug Manufacturing Controls
    • ISO 9001:2015 quality management for manufacturing audit traceability

    Typical usage ratio

    • 0.5–2.0% by weight in total synthesis batch precursors; actual ratio adjusts according to target molecule yield and side-reaction suppression, optimized in pilot-scale runs

    Downstream process integration

    • Material enters early-stage ester hydrolysis or functional group conversion reactors, followed by catalytic hydrogenation and selective oxidation
    • Feeds into multi-stage purification lines, typically crystallization and solvent extraction systems before API coupling steps

    Final product types

    • Androgenic active pharmaceutical ingredients (APIs)
    • Intermediates for corticosteroid drugs
    • Prohormone and metabolic pathway research substances

    2. Veterinary Hormonal Additive Manufacturing

    Veterinary pharmaceutical factories incorporate epiandrosterone acetate into compounded hormonal premixes designed for controlled livestock reproduction programs, with usage strictly limited to countries and species where permitted. Compliance with local veterinary drug standards guides every step, including batch release and withdrawal period calculations. The raw material undergoes blending and micronization to achieve particle size distribution compatible with veterinary dosing protocols.

    Industry compliance standards

    • Veterinary International Conference on Harmonization (VICH) Guidelines
    • Good Manufacturing Practice for Veterinary Drugs (GMP-Vet, where applicable)
    • Specific National Authorizations: European Medicines Agency (EMA) requirements for veterinary products; US FDA Center for Veterinary Medicine (CVM) directory
    • ISO 17025-accredited batch analytics for residue control

    Typical usage ratio

    • 100–300 mg per kg premixed base (0.01–0.03%) depending on animal species and dosage schedule; ratio established during controlled trials and adjusted for physiological factors

    Downstream process integration

    • Material feeds into ribbon blenders for dry premix formulations or onto granulation lines for slow-release injectable pellets
    • Undergoes sieving, in-process homogeneity testing, and batch revalidation before packaging

    Final product types

    • Veterinary injectable pellets (species-specific)
    • Oral powder or bolus forms for reproductive cycle management
    • Premixed feed additives for livestock hormone regulation

    3. Research-Grade Biochemical Reagent Production

    Biochemical sector manufacturers rely on the purity and reproducibility of epiandrosterone acetate for laboratory reagent kits, where it serves as a reference standard in enzyme activity assays, receptor-binding studies, and internal control solutions. High-purity batches are processed in ISO-certified environments, with accompanying documentation to support trace analysis and reproducibility for downstream research applications.

    Industry compliance standards

    • ISO 9001 and ISO 17034 for reference material manufacturers
    • OECD Principles of Good Laboratory Practice (GLP) for research reagent supply chains
    • Batch documentation under GxP for laboratory traceability
    • Material Safety Data Sheet (MSDS) conformance and shelf-life verified according to Reach Regulation (EC) No 1907/2006

    Typical usage ratio

    • 1–10 μg/mL in final analytical assay solutions, typically prepared from a 99% reference grade solid; concentration tailored to sensitivity of analytical instrument

    Downstream process integration

    • Product dissolves directly into solvent systems for kit assembly or as standard calibrant preparation for high-throughput screening platforms
    • Filtration and sterile packaging follow lyophilization where required, with batch aliquotization for laboratory end-users

    Final product types

    • Analytical control standards for LC/MS or GC/MS applications
    • Biochemical enzyme assay kits
    • Hormone receptor-binding research reagents

    4. Commercial Fitness & Sports Science Formulation

    Sports nutrition brands legally operating under regional dietary supplement frameworks formulate regulated muscle-supporting blends containing epiandrosterone acetate for research and export-only markets, subject to robust compliance checks. Manufacturers focus on microencapsulated granules and precise dosage capsule lines to ensure uniformity and safety profiles appropriate for controlled-release nutritional studies. All lots undergo third-party analytical verification to prevent cross-contamination and ensure accurate labeling.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP, 21 CFR Part 111) for Dietary Supplements (USA)
    • EFSA Food Additive and Ingredient Regulation (EC No 1333/2008) – where applicable for EU export
    • Prohibited Substance Screening: World Anti-Doping Agency (WADA) monitoring and import/export rules
    • Third-party batch analytics for label claim validation (NSF Certified for Sport, where required)

    Typical usage ratio

    • 5–50 mg per single serving, controlled by encapsulation weight and compliance with site-specific regulatory maximum limits

    Downstream process integration

    • Material introduced during microencapsulation or direct blending into the capsule powder matrix immediately after particle sizing
    • Incorporates into automated filling and tamper-evident packaging lines; batch sampled for purity and homogeneity

    Final product types

    • Microencapsulated fitness research supplements
    • Hard-shell capsules for export markets adhering to notified country regulatory thresholds
    • Controlled-release sports science tablet prototypes (for R&D, not OTC sale in regulated jurisdictions)
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    Certification & Compliance
    More Introduction

    Epiandrosterone Acetate: Practical Insights from a Chemical Manufacturer

    What Epiandrosterone Acetate Brings to Specialized Manufacturing

    In recent years, Epiandrosterone Acetate has stood out among hormone-related intermediates. As a chemical manufacturer working directly at scale, we see the growing demand in pharmaceutical synthesis, research, and specialty products. This compound draws attention because it derives from epiandrosterone — a naturally occurring steroid hormone — and gains unique properties through acetylation. That small chemical transformation changes how the molecule interacts within both industrial and laboratory settings, opening new opportunities that wouldn't exist with the parent compound alone.

    The product emerges as a white or near-white crystalline powder. We produce Epiandrosterone Acetate under controlled conditions, maintaining high purity — typically above 98% as determined by HPLC analysis. Melting point, moisture content, residual solvents, and appearance all receive careful supervision. Most batches register a melting point in the expected range for acetate esters, while impurities get driven down below recognized detection limits. Practical use requires this purity level; we’ve learned the difference in outcome when even a small contaminant throws off a multi-step synthesis.

    Applications in Industry and Research

    Epiandrosterone Acetate provides value for several groups — pharmaceutical development, academic research, and specialty chemical synthesis benefit most. In our labs, we’ve seen this compound support hormonal studies, especially when researchers want to explore how esterified derivatives perform relative to non-esterified hormones. The acetate group changes solubility, bioavailability, and sometimes the rate at which the molecule breaks down in biological systems. This makes it more attractive for some in vivo experiments and preclinical drug development.

    Several research teams use Epiandrosterone Acetate for preparing analogs to test androgenic and anabolic activity. By extending the ester chain, chemists slow down deacetylation in the body. This means the molecule provides a longer-lasting profile compared to the parent epiandrosterone — a consideration in designing both animal studies and early-stage drug prototypes. We’ve supported projects aiming to map metabolic conversion, receptor affinity, or observe the effects of slow-release hormone delivery.

    Differences Behind the Scenes: Epiandrosterone Acetate Versus Related Compounds

    On the factory floor and in QC labs, the differences between Epiandrosterone Acetate and related molecules aren’t just academic. Unmodified epiandrosterone has limited solubility in certain organic solvents, making it tricky when scaling multi-gram or kilogram lots for contract synthesis. The acetate ester handles modern solvents much better, offering smoother reactions and easier downstream purification.

    Structurally, Epiandrosterone Acetate carries the standard androstane backbone — but the acetylation alters both its reactivity and usability. In practical chemical processing, that small shift can shorten reaction times and reduce waste. These factors lower costs for our customers and avoid disruptions—a lesson we’ve learned through countless batch records and troubleshooting sessions. Some customers ask for both forms, looking to directly compare how a minor chemical modification alters the end product.

    The acetate form also stores more reliably. For unmodified hormones, even moderate humidity in a storeroom can shorten shelf life and cause caking or degradation. Our experience shows that Epiandrosterone Acetate withstands shipping, long-term storage, and handling conditions with fewer complaints from logistics teams. Drawbacks rarely show up until a container is exposed to air for a very long period; with careful sealing and common desiccants, we don’t see an uptick in failed batches.

    Quality Commitment and Process Insights

    Everything begins with raw material sourcing. The best results start with high-quality androstane derivatives, and we’ve invested in strong supply chain relationships. Purification techniques — including recrystallization, phase separation, and vacuum drying — strip out unwanted byproducts. Each lot runs through chromatography, confirming identity and removing even faint odor-causing substances that can cause trouble in sensitive research applications.

    For those running downstream chemistry, this product slot into known methods for introducing further modifications. Esterified compounds like Epiandrosterone Acetate let chemists access a broader pool of analogs. This is helpful when optimization requires fine-tuning physical or biological properties. Diligence in analytical testing pays off here: both us and our long-term users note consistent melting behavior, repeatable TLC and HPLC retention times, and predictable yield in conversion to other derivatives.

    Many users take pride in traceability — and so do we. Every drum or pouch comes labeled with unique batch numbers tied directly to a full suite of in-house testing reports. Feedback loops, both internal and from customer labs, have shaped our SOPs. When even a single lot comes back with chromatography problems or off-color appearance, we invest time in root-cause analysis instead of glossing over the issue. That cycle of improvement is non-negotiable for us as the manufacturer.

    Why Direct Manufacturing Changes the User Experience

    Companies often ask what difference it makes to get Epiandrosterone Acetate straight from a chemical producer. Decades on the shop floor have taught us that subtle variations creep in when product passes through too many hands. Direct feedback from working scientists shapes not only specifications but process changes and documentation. Technical support comes from people actually responsible for production, not a distant distributor.

    Many research teams prefer to handle only the quantity they need, and we recognize those needs shift quickly. Manufacturing in-house makes it possible to respond with custom pack sizes and documentation aligned with the demands of regulatory inspections or grant audits. We know batches sometimes stall; sometimes access to testing data or a rapid retest makes the difference between a research breakthrough and wasted funding. By controlling every step, we can respond directly instead of waiting for information to travel through a chain of brokers.

    Industry Shifts and Future Outlook

    Epiandrosterone Acetate’s demand tracks with broader changes in hormone research and therapeutic development. New delivery platforms — patches, gels, slow-release tablets — all put pressure on ingredient manufacturers to offer more consistent intermediates. Pure acetate derivatives reduce complications later in the pipeline, whether in formulation or in regulatory documentation. As experienced chemical manufacturers, we stay tuned to what these trends require from process controls, not just the molecule itself.

    The regulatory landscape, especially for hormone-related substances, often requires swift adaptation. Our QA/QC teams spend substantial effort ensuring documentation stands up to closer scrutiny. Each shipment moves with laboratory certificates and, if needed, trace impurity screening for target elements. As new standards appear in the US, Europe, or Asia-Pacific, we adjust equipment calibration and SOPs without waiting for the next compliance cycle. That agility isn't a buzzword — it's built into daily routines.

    Supporting Solutions for Common Industry Concerns

    Some practitioners voice concerns about product consistency and the risk of batch-to-batch variability when working with specialty chemicals. Over years in business, we’ve seen how an inconsistent intermediate can introduce costly errors downstream. We maintain strict batch control, and anyone visiting our facility would see the checks during blending, packaging, and pre-shipment verification.

    For end users worried about documentation, we offer comprehensive analytic packages for every run. GC, HPLC, IR, and mass spectrometry profiles stay attached to every shipment record. This enables faster turnaround for method validation in regulated environments. Failures or discrepancies receive individual investigation — it’s easy to trace origins and correct course because every process stage happens in a single facility, under familiar supervision.

    Shipping specialty hormone intermediates brings added risks — from transit exposure to customs delays. We adopted robust packaging protocols, including multi-layer barriers and vacuum-sealed portions. Regular audits and retraining ensure loading and handling teams avoid shortcuts. The investment in staff and process pays dividends with fewer returned shipments or out-of-spec complaints, which become clear in internal performance reviews and customer satisfaction surveys.

    Industry Partnerships and Continuous Improvement

    Part of reliable supply means working directly with those building new therapeutic products or research protocols. Department leads and principal investigators appreciate the transparency and access to technical discussion. We invite regular visits and encourage open communication, which helps both sides spot issues early—whether it’s a process bottleneck or a specification mismatch for a newly designed experiment. Our technical support draws from hands-on manufacturing experience, not canned responses.

    Ongoing research within the lab addresses opportunities for further process development — improved solvent recovery, energy efficiency in acetylation, and greener purification interventions often grow from joint discussions with partners. We value feedback most when it points out overlooked details, such as solvent compatibility or leftover trace solvent issues. These insights directly inform how we allocate staff and resources, gradually lifting quality year over year.

    Responsibility for End Uses

    Handling hormone intermediates like Epiandrosterone Acetate calls for respect. As a manufacturer, we place strong emphasis on educating customers about both legal and scientific implications of use. The regulated nature of these compounds means we vet customers before shipping and restrict access where law or ethics require it. Our documentation clarifies permitted applications, helping customers navigate research ethics, compliance, and documentation hurdles.

    We emphasize safe handling directly in conversations with receiving teams. Our shipments travel with clear labeling, and we keep reference data on storage, environmental management, and emergency response. Years of experience highlight how even a minor lapse in these areas can create unexpected complications. Reliable partners accept this diligence not as a burden, but a guarantee that products won’t introduce unnecessary risk to their process or team.

    What Sets Manufacturer-Centric Production Apart

    Years spent refining every detail — from raw material selection to choosing drying equipment — pay off in more predictable performance. Labs and factories working with Epiandrosterone Acetate get the benefit of shared experience. Mistakes, large and small, guide improvements that build resilience into the entire product chain. We have seen how the smallest process tweaks, such as a change in solvent filtration or a shift in blending time, can influence both purity and usability. In our experience, rapid feedback loops form the backbone of high-quality production, and direct, person-to-person communication reduces the risk of overlooked issues.

    A consistent product makes a difference. Pharmaceutical R&D, academic projects, and specialty contract production all see reduced downtime and greater certainty in method development when unexpected variability drops out of the process. The cumulative effect: higher rates of project success, easier troubleshooting, and fewer costly reruns. Stories from the field reinforce the value, as researchers and industrial partners report faster validation and cleaner profiles than with intermediates purchased through non-manufacturer channels.

    Community and Environmental Commitments

    Running a chemical manufacturing operation means a constant balance between efficiency and environmental responsibility. For Epiandrosterone Acetate, this translates into thorough emissions controls, wastewater management, and careful raw material sourcing. We operate within the bounds of local and national law, but the internal standards we set are higher. Regular audits and partnerships with environmental consultants help identify and neutralize risks before they become problems.

    Our approach relies on steady improvement instead of one-time fixes. For example, recent investments in closed-loop solvent recovery have lowered the environmental burden and operating cost. Employee training programs cover both technical skills and ethical decision-making. These investments build trust among regulators and the local community while reinforcing the long-term sustainability of specialty chemical manufacture.

    Looking Forward

    The future for Epiandrosterone Acetate depends on more than market size or regulatory climate. Ongoing innovation in both research applications and production technology will determine which suppliers remain reliable long-term partners. As a direct manufacturer, we concentrate on steadily improving transparency, responsiveness, and scientific integrity. Customers notice when they deal directly with manufacturing teams committed to these principles.

    We see opportunities emerging in custom synthesis, specialized formulation, and expanded research support. A willingness to share both successes and setbacks creates a foundation for true partnership. Researchers and product development teams find greater efficiency, accountability, and predictability because the product—and the story behind it—come from a team that handles each detail, from start to finish.