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HS Code |
933264 |
| Cas Number | 1975-78-6 |
| Molecular Formula | C12H23N |
| Molecular Weight | 181.32 g/mol |
| Iupac Name | dodecanenitrile |
| Synonyms | lauronitrile, n-dodecanenitrile |
| Appearance | colorless to pale yellow liquid |
| Boiling Point | 265-267 °C |
| Melting Point | 20-22 °C |
| Density | 0.824 g/cm³ at 25 °C |
| Solubility In Water | insoluble |
| Flash Point | 120 °C (closed cup) |
| Refractive Index | 1.438 (at 20 °C) |
| Logp Octanol Water | 5.1 |
As an accredited Dodecanenitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Dodecanenitrile, 100 g, supplied in a sealed amber glass bottle with tamper-evident cap, labeled with safety and hazard information. |
| Shipping | Dodecanenitrile should be shipped in tightly sealed containers under cool, dry, and well-ventilated conditions. It must be clearly labeled and packaged according to regulations for organic chemicals. Avoid heat, sparks, and open flames during transport. Follow all relevant local, national, and international shipping guidelines for hazardous materials. |
| Storage | Dodecanenitrile should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Keep it away from heat and direct sunlight. Storage should be in accordance with local, regional, and national regulations, ideally in a chemical storage cabinet suitable for organic compounds. |
Applications of Dodecanenitrile in Industrial ManufacturingDodecanenitrile serves as a vital intermediate for multiple high-value sectors. Its chemical properties and reliable supply chain support precise downstream integration in specialty chemicals, agrochemicals, pharmaceutical intermediates, plasticizers, and surfactants. As a dedicated manufacturer, we ensure our material meets all relevant quality and regulatory requirements for these demanding applications. 1. Synthesis of Lubricant AdditivesDodecanenitrile acts as an essential precursor in formulating alkylated amines and corresponding quaternary ammonium compounds for high-performance lubricant additives. In this sector, the compound undergoes catalytic hydrogenation to deliver secondary and tertiary amines, which contribute to anti-wear, corrosion inhibition, and dispersant functionalities in engine oils and industrial lubricants. Downstream processes require careful control of reaction conditions to avoid side product formation and guarantee batch reproducibility, especially when producing amine derivatives suitable for high-temperature and high-shear environments. Industry compliance standards
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2. Manufacturing of Pharmaceutical IntermediatesDodecanenitrile is widely used in producing intermediates for APIs, notably in the synthesis of long-chain aliphatic amines used as building blocks in anesthetics, antihypertensives, and CNS drugs. The nitrile undergoes catalytic reduction to the corresponding amine, which then undergoes functional group modifications, including acylation, sulfonation, or alkylation. GMP controls and impurity profiling are critical at each processing step as required by global drug regulatory guidelines, especially for export-oriented manufacturers and CDMOs supplying regulated markets. Industry compliance standards
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3. Agrochemical Formulation IntermediateAgrochemical manufacturers utilize dodecanenitrile as a key raw material for the synthesis of specialized herbicide and insecticide adjuvants, such as alkyl amines and their salts. Through controlled hydrogenation and subsequent neutralization, the resulting amines find use as emulsifiers, wetting agents, and solubilizers. These intermediates improve the distribution and biological efficacy of active crop protection compounds. Formulators must monitor residual unreacted nitriles rigorously due to regulatory residue controls on export and domestic agrochemicals. Industry compliance standards
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4. Surfactant and Detergent Intermediate ProductionDodecanenitrile is an important intermediate in the manufacture of long-chain alkylamines, which serve as precursors for amphoteric, cationic, and nonionic surfactants used in I&I cleaning agents and textile auxiliaries. The material undergoes reductive amination, followed by ethoxylation or quaternization, depending on the downstream application. Stringent control of nitrogen impurities and chain homogeneity is required, as performance in foaming, emulsification, and cleaning correlates directly with molecular uniformity established during upstream processing. Industry compliance standards
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5. Plasticizer and Polymer Additive ManufacturingProducers of flexible plastics and polymer composites employ dodecanenitrile-derived amines as chain extenders, plasticizers, and antistatic additives. Immobilized reduction and subsequent derivatization yield specific long-chain alkylamines which, once incorporated, enhance flexibility, reduce processing temperature, and improve electrical properties. Such intermediates suit PVC, polyurethane, and polyamide compounding, with migration and extraction behavior regulated to meet regional and international materials compliance sets. Industry compliance standards
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Competitive Dodecanenitrile prices that fit your budget—flexible terms and customized quotes for every order.
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Here on the floor, you can feel the substance of work that goes into every batch of dodecanenitrile we produce. We’re not a voice hiding behind a computer screen or brokers piecing together shipments—this is years of hands-on experience, tanks full of raw materials, and every step backed by the skill of expert chemists. Our process stretches from the careful sourcing of starting materials to the fine details of distillation, filtration, and packaging. With dodecanenitrile, or laurylonitrile, the chemistry bridges both discipline and practical know-how. This compound, known for its linear C12 backbone and terminal nitrile group, doesn’t just appear on its own: it results from rigorous synthetic pathways, typically involving dehydration of primary amides or cyanation of dodecane precursors, fine-tuned by those who truly understand how to keep batch quality consistent.
Dodecanenitrile surfaces in a world where not all nitriles meet the same performance standards. A 98% minimum assay level matters; it’s easy to claim on paper, but maintaining this—every drum, every shipment—is something customers come to expect from manufacturers, not traders repackaging mixed lots. A lot rests on minimizing byproducts. Even a small variance in color, impurity profile, or melting range can put off an end user, especially where cosmetic or fine chemical intermediates are involved. We've learned—as any chemical pyrotechnician will—that consistency doesn’t happen by accident. Quality audits, in-process control charts, and batch comparison data drive our decisions, not marketing blurbs or generic praise.
The physical reality of production gives us a close look at the specifications that genuinely make a difference. Dodecanenitrile is clear to pale yellow, typically liquid just above room temperature, but even slight contamination with colored impurities signals an issue upstream. For synthesis applications, this matters: when clients want to reduce dodecanenitrile to dodecylamine, or need a nitrile group as a functional handle, trace impurities can poison catalysts and build up in final products. Through years of optimizing reflux times, carefully controlling temperatures, and working closely with maintenance to keep equipment surfaces uncontaminated, we cut off these small but impactful problems before they reach the final product.
As working chemists and plant engineers, we follow dodecanenitrile beyond the doors of our facility. This compound doesn’t simply fill an order sheet—its applications echo across other manufacturers’ lines too. Primarily, dodecanenitrile stands as a solid starting point for specialty amines. Through hydrogenation, chemists can produce dodecylamine, which feeds into multiple value chains from surfactants and corrosion inhibitors to plastic additives and agrochemical intermediates. Our own feedback loops with customer technical teams point out how a clean nitrile reliably shapes a smoother amine synthesis, sparing them troubleshooting batches with off-odors or excessive side reactions.
Sometimes, a customer’s technical service engineer calls and describes small foaming inconsistencies in a cationic surfactant they’re formulating. Such process headaches often trace back to the purity and structural uniformity of the initial nitrile. Our knowledge runs deeper than a specification sheet; it’s a feedback-rich conversation that flows both ways between us and our customers’ development labs. Years ago, after multiple requests from a client specializing in specialty lubricants, we iterated on our process to achieve a tighter control over the boiling range and reduce trace amine content—direct responses to real challenges the client faced further along the value chain.
Beyond amine synthesis, the applications widen: dodecanenitrile acts as a key intermediate in certain fragrances and flavors. Chemists appreciate the straight-chain structure; it lays the groundwork for clean, linear aldehydes and acids, pivotal in high-value aroma chemicals. Without a clean starting nitrile, odd odors slip into the finished blends, and nobody in perfumery tolerates off-notes or background taint. Here, quality translates into market credibility downstream.
And then there’s research and polymer chemistry. Some groups use dodecanenitrile as a co-monomer precursor or analytical standard for chromatography. These uses might look esoteric, but the expectations for batch clean-up, packaging, and documentation only intensify at these scales. We supply technical support documentation and batch-specific data directly, never through layers of red tape or unexplained delays. Customers developing new materials rely on knowing exactly how our dodecanenitrile was made, right down to which reactor produced which batch, along with its analytical certificate showing real GC and IR data, not just generic claims.
Those on the plant floor know that dodecanenitrile differs fundamentally from shorter-chain alkyl nitriles like butyronitrile or octanenitrile. The linear C12 carbon skeleton offers higher hydrophobicity, less volatility, and different chemical reactivity—characteristics that fit certain applications and shut out others. Some seekers of octanenitrile or decanenitrile think longer chain length just means “more of the same,” but chemistry rarely works so simply. Evaporation rates, solvent compatibility, and downstream hydrogenation conditions all shift with carbon chain length, affecting foul odor release, flammability, and solubility behavior.
We run actual distillation curves—not just what shows up on a data sheet. Dodecanenitrile’s boiling point, much higher than shorter nitriles, impacts handling during large-scale syntheses. At elevated temperatures, the risk of decomposition lowers, which helps customers who hydrogenate under pressure. Our technical teams flag these distinctions up-front, sharing in-process guidance to avoid surprises. People working with mid-range nitriles sometimes forget that solvent carryover or residue amounts change with molecular weight; direct feedback from us as manufacturers means fewer headaches for downstream processors.
Another distinction lies in odor profile. Any worker who’s unloaded a drum in mid-summer knows that chain length strongly influences volatility and background odor. Dodecanenitrile carries less of the sharp, acrid scent common to short-chain nitriles, lending itself better to applications in fragrances or scenarios where operator exposure matters. This practical aspect escapes those without real plant experience—something brought home when we walk a customer’s QC manager through sample batch differences in person.
On solubility, linear dodecanenitrile’s low polarity means it behaves differently than aromatic nitriles like benzonitrile, or even branched chain analogs. Skilled formulators recognize these subtle shifts, especially when blending for surfactant systems, customizing chemical intermediates, or shaping coatings. True product support starts with this level of detail, not just moving boxes. Regular lab trials in our application lab continually test and confirm these distinctions, with our feedback fueling the fine-tuning of customer processes.
Making and handling dodecanenitrile isn’t a desk exercise. Safety permeates every decision at the plant. At our facility, rigorous operator training, vapor handling systems, and airtight process controls serve as daily guardrails, not just checkboxes on a form. Dodecanenitrile doesn’t carry the same acute toxicity hazard as short-chain nitriles, but its contact and inhalation risks still require vigilance. Ongoing review of exposure data leads us to update standard operating procedures—sometimes prompted by an on-the-ground incident, sometimes by changes in regulatory guidance. As environmental standards tighten globally, plant water and air emissions monitoring track every batch, identifying where traces might arise and stemming them long before any regulatory agency steps in.
Waste management goes beyond incineration or disposal. We look at raw material usage, recycle process streams where possible, and consult with environmental engineers to reduce both chemical and energy footprints. In some cases, process changes that cut impurities also improve yield and reduce solvent use—decisions rooted in plant knowledge and a meaningful understanding of responsibility. Any chemical manufacturer serious about long-term business sees this as a core part of daily operations, not just a quarterly talking point.
In the real world, problems aren’t solved by generic advice; it’s about meeting challenges head-on and shaping the process when issues arise. Years back, a regional plastics producer ran into batch failures related to dissolved gases contaminating their hydrogenation step. Company engineers sent us samples, and together we traced the issue to residual, low-level unsaturation in the dodecanenitrile—something virtually undetectable without in-house high-sensitivity GC instruments. Addressing the cause meant recalibrating the dehydration logic in our primary reactor, upgrading analytical routines, and working side-by-side with their technical staff until the defect vanished, for good. That’s what a manufacturing relationship brings to the table: direct, actionable solutions built on technical experience, not a generic “we apologize for the inconvenience” message.
Shared experience also plays out when timelines suddenly tighten. Plant outages, seasonality in demand, or logistics delays call for direct lines of communication between manufacturing teams. As producers, we have firsthand knowledge of where process slack exists—or doesn’t. We don’t promise what our plant can’t deliver: instead, we prioritize shipments based on mutual understanding of shelf life, demand forecasts, and even anticipated future orders. Operational transparency on the supply side positions customers to plan ahead, especially when formulating around long-chain intermediates that can’t be swapped out last minute like commodities. For us, every truckload leaving our facility carries not just drums of dodecanenitrile but the trust of partners who count on reliability above empty marketing claims.
Our approach builds on a culture of learning, not just for regulatory compliance but to actually get better at what we do. The most valuable process improvements have started with someone on the floor noticing a pattern—a slight temperature shift resulting in better purity, or a maintenance technician recommending new pump seals that cut batch-to-batch variability. These lessons don’t make headlines, but collectively they define the technical backbone every demanding customer depends on. As we adopt new analytical technologies—like better FT-IR for impurity mapping and real-time process modeling—we see measurable jumps in both efficiency and finished product quality, which allows us to push purity higher and reject off-spec lots before problems mushroom.
Continuous training and knowledge-sharing also cut across departments. Operating dodecanenitrile units requires a mix of chemical intuition and a feel for equipment. New hires learn from senior operators directly, not through generic online modules. When someone at the blending tank shares a shortcut that wastes less solvent and shaves minutes off process time, the impact outlasts any policy update from above. It’s these day-to-day exchanges—built on respect, hard-earned skills, and a sense of ownership—that drive both product quality and cost control.
Feedback loops with technical customers root product improvements in real data. After one R&D team mentioned a trace impurity complicating downstream isocyanate reactions, we collaborated for weeks to change upstream purification, shorten reaction times, and lock in a new continuous sampling protocol. This collective process delivers cleaner dodecanenitrile for all our partners down the line. Every gain in performance or yield began as a challenge, then got solved through plant-side dialogue and customer candor.
With growing demands for performance chemicals, batch-to-batch traceability, and environmental transparency, direct relationships with actual producers increasingly matter. We see firsthand how chemists in pharmaceuticals, polymers, and specialty chemicals rely on supplier reputation, real-world experience, and technical openness—not just lower-cost offers. Whether you’re scaling a process or facing regulatory scrutiny, the consequences of impurities or unpredictable supply can derail months of work. Customers choosing dodecanenitrile want suppliers with a stake in the outcome, not silent intermediaries looking to move product twice removed from its origin. Long-term, both parties benefit most from a partnership shaped by practical experience, knowledge transfer, and genuine problem-solving.
We keep investing in staff skills, plant reliability, and analytical tools because that’s what allows customers to actually build value on top of our work. It’s not only about this year’s orders, but about helping drive the next round of innovation, process safety, and market trust. With every tank farm upgrade and lab method developed, we remind ourselves that every kilogram of dodecanenitrile shipped reflects the effort, judgment, and collaboration of the people who actually make it. The difference shows in customer results, not just in test certificates or guarantee statements. That’s the mark of a manufacturer who stands behind every product.