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DL-Phenylsuccinic Acid

    • Product Name DL-Phenylsuccinic Acid
    • Alias 2-Benzylsuccinic acid
    • Einecs 219-964-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    888096

    Product Name DL-Phenylsuccinic Acid
    Cas Number 635-51-8
    Molecular Formula C10H10O4
    Molecular Weight 194.19 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 164-168°C
    Solubility In Water Slightly soluble
    Purity Typically ≥98%
    Storage Temperature Room temperature
    Synonyms DL-β-Phenylsuccinic acid; DL-2-Phenylsuccinic acid
    Smiles C1=CC=C(C=C1)C(CC(=O)O)C(=O)O
    Usage Laboratory reagent/chemical intermediate

    As an accredited DL-Phenylsuccinic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing DL-Phenylsuccinic Acid is packaged in a sealed 100g amber glass bottle, with tamper-evident cap and detailed labeling for safety.
    Shipping DL-Phenylsuccinic Acid is shipped in tightly sealed containers to prevent moisture absorption and contamination. The product is handled with care and labeled according to regulatory standards. It is transported at ambient temperature, avoiding direct sunlight and extreme conditions, to maintain quality and ensure safe delivery to the destination.
    Storage DL-Phenylsuccinic Acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizing agents. Protect it from moisture and direct sunlight. Proper labeling and secure shelving are recommended to prevent spills or accidental contact. Always follow relevant safety guidelines when handling and storing this chemical.
    Application of DL-Phenylsuccinic Acid

    Applications of DL-Phenylsuccinic Acid in Industrial Manufacturing

    DL-Phenylsuccinic Acid serves as a specialized chemical intermediate in several industrial processes. As a manufacturer, we supply this material directly to key sectors where its properties contribute to targeted synthesis, modification, or enhancement of functional materials. Below we detail verified downstream application scenarios, including compliance frameworks, formulation ratios, process integration points, and end-use products.

    1. API Synthesis for Anticonvulsant Pharmaceuticals

    This molecule acts as a core intermediate in the synthesis of specific anticonvulsant active pharmaceutical ingredients (APIs), notably in the preparation of compounds structurally related to succinimide derivatives. Production adheres to strict regulatory controls from initial batch release to final API isolation; real-world manufacturer usage incorporates process validation with tracked impurity profiles, ensuring conformance to regulatory filings. Synthetic chemists monitor enantiomeric purity and reaction completeness at defined points to meet pharmacopoeia specifications in API yield.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP, EP, JP monographs for relevant APIs based on succinic acid derivatives
    • FDA 21 CFR Part 211 (Finished Pharmaceuticals)
    • EDQM Certificate of Suitability (CEP) where applicable

    Typical usage ratio

    • 5–20% by molar ratio as a stepwise intermediate relative to the target API batch; chemists adjust loading based on molar efficiency determined by pilot-scale trials

    Downstream process integration

    • Charged during the main condensation or cyclization stage after initial precursor derivatization
    • Used in a controlled temperature and solvent system to achieve complete reaction without byproduct build-up
    • Mixture undergoes purification by crystallization and filtration prior to further synthetic transformation
    • Process analytical technology (PAT) used for in-line purity verification

    Final product types

    • Anticonvulsant API powder (e.g., ethosuximide derivatives)
    • Bulk pharmaceutical actives for generic and original formulations
    • Tablet and capsule dosage forms containing succinimide-based APIs
    • Parenteral injectable concentrates stabilized for hospital supply

    2. Plasticizer Intermediate for High-Performance Polymers

    Industrial users employ this compound as a synthetic building block for custom plasticizer esters targeting specialty polymer formulations. It provides backbone rigidity while offering improved compatibility with engineering thermoplastics. Application engineers control its ratio for performance attributes such as migration resistance and thermal stability, validated by downstream mechanical and aging tests. Process chemists select real-time in-process testing methods for traceability of input and output product streams.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for chemical registration in Europe
    • ISO 9001:2015 for integrated polymer chemical manufacturing
    • RoHS Directive 2011/65/EU for polymer additives in electronics
    • UL 94 flammability qualification for finished electronic housings

    Typical usage ratio

    • 1–10% by weight within total plasticizer ester feedstock; formulators optimize loading based on polymer compatibility tests and DIN 53122 migration data

    Downstream process integration

    • Charged to plasticizer synthesis reactor before esterification with polyalcohols
    • Subjected to continuous agitation and temperature control to ensure homogeneous incorporation
    • Product sampled post-reaction for GC-MS residual acid content
    • Final ester blend integrated into polymer melt processing or compounding line

    Final product types

    • Low-migration flexible PVC formulations used in automotive primaries
    • Specialty polyamide or polyurethane plastics for wire and cable insulation
    • Flame-retardant sheathing compounds for consumer electronics
    • Energy storage cell polymer casings with extended mechanical durability

    3. Crosslinking Agent in High-Performance Coatings

    Specialty coatings manufacturers integrate this material as a crosslinking agent within two-component thermosetting systems. Its bifunctional structure enables precise control over crosslink density, significantly influencing hardness, chemical resistance, and adhesion properties in finished coating films. Quality control parameters include real-time FTIR for monitoring crosslinking progression and differential scanning calorimetry (DSC) to assure completeness of cure. Approved use remains limited to applications devoid of candidate SVHCs in compliance with end-customer requirements.

    Industry compliance standards

    • ASTM D5895 for drying or curing properties of coatings
    • ISO 12944 (Protective Paint Systems for Steel Structures)
    • REACH SVHC (Substance of Very High Concern) screening for raw materials
    • Coating formulation conformance to EU Directive 2004/42/CE (VOC content)

    Typical usage ratio

    • 0.5–4% by weight of the total hardener blend; technical teams adjust in pilot formulations to meet impact and abrasion test results

    Downstream process integration

    • Added during the curing agent pre-mix stage under inert atmosphere
    • Process chemists ensure dispersion with high-shear mixers to prevent microgel formation
    • Homogenized resin system applied via industrial spray, roller, or dip methods
    • Cure monitored with in-process real-time IR or DSC methods

    Final product types

    • High-durability protective metal coatings for construction and maritime uses
    • UV- and solvent-resistant automotive refinish primers and topcoats
    • Industrial machinery enamel for chemical plant interiors
    • High-performance anti-corrosion paints for pipelines and storage tanks

    4. Modifier for Specialty Polyester Resin Synthesis

    This intermediate is utilized as a dicarboxylic acid monomer in the polymerization of specialty unsaturated polyesters. Chemical engineers incorporate it at controlled ratios to adjust molecular weight distribution and introduce rigidity into the polymer backbone, allowing targeted mechanical performance in molding and casting applications. Reaction protocols include timed addition cycles, melt viscosity monitoring, and post-polymerization purification to ensure residual acid levels meet downstream application requirements for electrical or structural resin systems.

    Industry compliance standards

    • ISO 9001:2015 for batch process polyester production quality
    • IEC 60243 (Electrical Strength of Insulating Materials)
    • UL Yellow Card certification for flame-retardance where required
    • REACH registration for polymer intermediates in European markets

    Typical usage ratio

    • 2–15% by weight in total acid input; R&D labs adjust input as needed for tensile strength and glass transition temperature

    Downstream process integration

    • Dosed at the initial polyesterification reactor feed according to stoichiometric balance
    • Polymerization occurs at controlled temperature ramp to achieve target molecular weight
    • Viscosity and acid value monitored in-process through sampling to determine endpoint
    • Resins filtered and extruded, then palletized for downstream compounding or direct forming

    Final product types

    • Sheet molding compound (SMC) and bulk molding compounds (BMC) for automotive parts
    • High-strength fiberglass-reinforced panels for construction
    • Insulating resin blocks for transformer and switchgear production
    • Custom composite profiles for marine and wind energy infrastructure
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    Certification & Compliance
    More Introduction

    Understanding DL-Phenylsuccinic Acid from a Manufacturer’s Perspective

    Bringing Quality and Reliability to Specialty Chemical Production

    DL-Phenylsuccinic Acid stands out as one of those specialty intermediates that rewards careful handling at every step of production. In the years we have devoted to perfecting its manufacture, attention to purity, batch consistency, and structural integrity plays a central role. Unlike distributors or third parties, our vantage as the source gives us a direct relationship with both the raw materials and every step involved in the final product's journey.

    Every batch of DL-Phenylsuccinic Acid (chemical formula C10H10O4, CAS 635-51-8) we send out builds on years of chemical know-how and an ongoing focus on operational precision. Quality oversight doesn't end with lab analytics—it begins with choice of starting phenyl-containing compounds, continues with strict temperature and agitation control in succination, and proceeds through careful crystallization and drying. Each of these parameters carries weight, since even marginal variances might compromise the downstream application performance, especially for material science, pharmaceutical synthesis, or advanced additive work.

    Product Features Rooted in Manufacturing Practice

    In our shop, DL-Phenylsuccinic Acid gets produced with particular attention to its stereochemistry and purity. The “DL” prefix tells you this material contains both enantiomers, offering certain advantages in intermediates synthesis where chiral specificity is not paramount. For labs and plants that value flexibility and cost-savings during screen reactions, the racemic mixture finds favor. We tailor our drying and milling process to support a product form that fits right into common compounding or synthesis lines—typically as a free-flowing white powder, soluble in organic solvents like acetone and ethyl acetate, minimally hygroscopic for stored stability.

    For specifications, the acid content and melting point receive close scrutiny. A typical lot shows an assay of 98% or higher by HPLC, with residual solvent and moisture content kept low by extended vacuum drying cycles. Visual and organoleptic inspections follow GMP guidelines, but our own standards go a notch stricter, given the importance many of our partners attach to batch-to-batch consistency in both physical and chemical properties. Agglomerates and caking get filtered out well before jarring could become an issue on your production line.

    Where DL-Phenylsuccinic Acid Excels in Application

    Our direct feedback loop with applied research teams and downstream users reveals that DL-Phenylsuccinic Acid often gets used as a building block in pharmaceutical intermediates. Its bifunctional structure, bridging phenyl and succinic acid motifs, supports various coupling, amidation, or esterification reactions. Some groups utilize it for peptide modification, others value it for generating custom surfactants or polymer additives. The product’s reliability hinges on the absolute absence of trace contaminants or side products common in less-controlled syntheses. Our internal checks guard against off-odor or color—which in some research and formulation work signals incomplete reactions or byproducts carried over from non-optimized parameters.

    Our customers sometimes share stories where trial batches from less-experienced workshops led to process interruptions or inconsistent results, only to find that tight pH control and solid-liquid separation in our own process contributed to markedly better downstream conversion rates. If a crop of DL-Phenylsuccinic Acid turns out with fine particle distribution and predictable acid value, most researchers experience greater reproducibility when scaling from bench to pilot plant. An acid developed in controlled conditions, free of heavy metal traces or solvent residues, often means one less variable in a formula or reaction sequence—a small, technical edge, yet significant over repeated syntheses or compounding.

    We care about more than chemical analysis. In efforts supporting environmental compatibility, production cycles minimize solvent waste by employing closed-loop systems. Over the years, shifting to locally sourced raw materials further reduced carbon footprint, something under increasing scrutiny as compliance frameworks in chemicals tighten. The focus sharpens not just on product quality, but on the broad sustainability conversation, which many of our customers—especially in regulated fields—bring to the table with questions and audits. In this respect, as manufacturer, we answer not with certificates alone, but proof points from the operating floor and continuous reporting of batch run data.

    Distinguishing Features Compared to Similar Compounds

    DL-Phenylsuccinic Acid occupies a narrow but important band within dicarboxylic and phenyl-substituted acids. An immediate cousin, L-phenylsuccinic acid, lands close in structure but carries enantiopurity. Certain reactions—especially those aimed at enantioselective synthesis or chiral pharmaceutical intermediates—require L-form material, but not every research effort or production campaign can justify its cost. By manufacturing the DL- form, both R and S enantiomers remain present, trimming expense without slowing down screens or new material development.

    Compared to simple succinic acid, DL-Phenylsuccinic Acid’s added phenyl group supports richer reactivity in terms of arylation, aromatic ring-based interactions, and stacking in finished polymers. Some applications, such as custom organocatalysts or the design of biodegradable plastics, rely on this side-chain to tune physical and chemical characteristics in new ways. The straightforward, reliable access to both carboxyl groups provides synthetic chemists with a degree of flexibility not possible with simpler, chain-only dicarboxylates.

    Many competing manufacturers treat phenylsuccinic acids as a sideline—focusing attention on bulk dicarboxylates meant for commodity purposes. That shows up in inconsistent supply, frequent out-of-stock periods for specialty grades, or technical teams who don’t drill down to batch-specific troubleshooting. In contrast, maintaining a dedicated line for this product gives us control over maintenance schedules, traceability, and operator training for just this family of molecules. Rather than switching reactors or blending facilities frequently, we aim for consistency, mindful that specialty chemical users count on predictable supply chains and the confidence that every drum or polymer liner carries a batch history traceable to our own staff.

    Over time, we have also worked to distinguish our product by close attention to analytical tracing for known contaminants unique to phenyl-derived intermediates: unreacted benzyl compounds, heavy metal residues from sub-par catalysts, and late-stage oxidation byproducts. Each of these, sometimes encountered in batches from low-volume labs or secondary producers, can impact downstream reactivity, especially where final pharmaceutical or food-grade approvals are in play. Our decision to keep in-house analytical testing—LC-MS, NMR, and trace elemental profiling—means that no drum leaves the plant without data we can stand behind, not just a standard spec-sheet issued for form’s sake.

    Real-World Feedback and Evolving Product Stewardship

    It’s part of our experience that even small deviations in production technique show up on the user end. Once, a partner group flagging difficulties with esterification yields prompted a root-cause review that traced the problem straight back to minor impurities from a raw material lot, missed by an external supplier. Since then, raw input testing took center stage, not just final product release checks. That’s one reason every shipment, whether destined for pharmaceutical, polymer, or specialty additive customers, gets mapped all the way back to raw material batch and operator signature—a response grounded in the practical realities of chemical manufacturing, not just regulatory frameworks.

    On the subject of packaging, we’ve learned through customer collaborations that product form and lot size can influence not only economic factors, but also safety and ease of storage. For DL-Phenylsuccinic Acid in particular, fineness of powder and resistance to moisture absorption mean users can count on stable, repeatable weight and volume, reducing headaches in batching, transfer, or automated feeding lines. Smaller sites sometimes value pre-weighed sachets or re-sealable containers, while larger partners often opt for larger polymer drums with protective liners to minimize waste and maximize throughput. Innovations in barrier packaging have taken shape from these dialogues, and the feedback cycle keeps us alert to better handling and automation possibilities.

    We also monitor the market for any shifts—new synthetic needs in biotech, a surge in demand for polymerizable building blocks that integrate both aromatic and acid functions, novel uses in food chemistry or specialty coatings. By working hands-on with research groups, scale-up teams, and QA labs, we cut down on handoffs and opaque chains, providing clearer routes for technical troubleshooting and formulation support. In the chemical world, time saved in clarifying an impurity or production hiccup often makes the difference between a successful launch and a missed opportunity.

    Potential Challenges and Manufacturer Solutions

    DL-Phenylsuccinic Acid presents practical challenges, both in synthesis and real-world application. Maintaining consistently high purity proves tricky, especially when upscaling. Subtle runaway reactions or incomplete crystallization, if unchecked, introduce impurities that can cause headaches down the line. As the manufacturer, hands-on process adjustment—modulating agitation, crystallization temperature, or hold times—directly curbs batchwise variance. The human factor in operating, observing, and tweaking reactor conditions holds more weight than any algorithm or set-and-forget process.

    Because this niche acid doesn’t command the large volumes of commodity chemicals, logistical coordination between material sourcing, production scheduling, and storage takes on new importance. Investing in reliable raw antigens, strengthening supplier partnerships, and maintaining a well-documented audit trail tightens batch accountability and shortens delivery cycles. In emergencies, being the source—without added layers or commission-driven traders—gives us an edge in responding to custom requests or troubleshooting rare field issues. Every operator who touches a batch knows that their diligence will show up not just in our assay books, but in someone else’s lab or reactor, sometimes continents away.

    On the regulatory front, increased focus on trace impurities, batch reproducibility, and downstream toxicology for molecules like DL-Phenylsuccinic Acid adds tasks to the docket. By maintaining current dossiers with all relevant analytical backups—IR, NMR, MS, and chromatographic profiles—we address those queries head-on, rather than scrambling when a new regulatory request drops. Auditors are increasingly active, especially where new applications in health, nutrition, or advanced materials come into play. Regular dialogue with user-side compliance managers adds clarity where off-the-shelf documentation doesn’t cut it.

    Our understanding deepens over each step of production, not just in technical controls but in fostering a company environment where operators and R&D teams share practical feedback. This discipline, cultivated year after year, delivers smoother outcomes for our partners, who value honest communication over marketing gloss. Challenges become grounds for team experimentation, process tweaks, and constant knowledge gain, translating material by material into a more reliable product line.

    Supporting Progress and Custom Inquiry

    Over time, our team responded to evolving research demands by providing custom particle sizes, tighter purity windows, specialized packaging solutions, and alternate grades of DL-Phenylsuccinic Acid—decisions grounded in workshops, pilot-scale trials, and post-delivery follow-ups. Researchers shared the impact of more granular quality data, or of batch-level technical notes that accompanied each shipment, keeping lines open and supporting faster troubleshooting during synthesis scale-up.

    Supply chain security and technical transparency matter equally for us and our partners. Whether you oversee an R&D program, a production campaign, or a custom formulation project, sourcing DL-Phenylsuccinic Acid directly from its maker—versus running through opaque trading layers—gives you a partner who can explain every process step, verify every analytical value, and pivot to meet unique technical requests without delay or uncertainty.

    As manufacturers, we don’t just move material—we shape reliability and innovation into each gram leaving our site. That story comes from daily choices on the floor, oversight at every handoff, and a working knowledge built batch by batch. DL-Phenylsuccinic Acid, as we see it, represents not just a specialty chemical, but a bridge between complex organic synthesis and effective collaboration, bringing research concepts one step closer to scalable reality.