Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing sales7@sinochem-nanjing.com 3389378665@qq.com
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DL-Lysine Monohydrochloride

    • Product Name DL-Lysine Monohydrochloride
    • Alias lysine-hcl
    • Einecs 214-818-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    452925

    Chemical Name DL-Lysine Monohydrochloride
    Molecular Formula C6H14N2O2·HCl
    Molecular Weight 182.65 g/mol
    Appearance White crystalline powder
    Solubility In Water Freely soluble
    Ph Of 1 Percent Solution 5.0-6.0
    Cas Number 923-27-3
    Melting Point 263-265°C (dec.)
    Storage Conditions Store in a cool, dry place
    Purity Typically ≥98%
    Odor Odorless
    Synonyms DL-Lysine hydrochloride

    As an accredited DL-Lysine Monohydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed 500g plastic bottle labeled "DL-Lysine Monohydrochloride," featuring purity, batch number, handling instructions, and hazard warnings.
    Shipping DL-Lysine Monohydrochloride is shipped in tightly sealed, moisture-proof containers to prevent degradation and contamination. It should be transported in cool, dry conditions, away from incompatible substances. Proper labeling per regulatory guidelines is essential, and material safety data sheets (MSDS) must accompany each shipment for safe handling and emergency reference.
    Storage DL-Lysine Monohydrochloride should be stored in a tightly closed container, in a cool, dry, and well-ventilated area. Protect the chemical from moisture, heat, and direct sunlight. Avoid exposure to incompatible substances such as strong oxidizers. Label the container appropriately and ensure it is kept away from food and drink to prevent accidental ingestion or contamination.
    Application of DL-Lysine Monohydrochloride

    Applications of DL-Lysine Monohydrochloride in Industrial Manufacturing

    As a manufacturer highly focused on quality and compliance, we provide DL-Lysine Monohydrochloride to global partners operating across diverse chemical industries. The following sections detail practical, large-scale applications supported by industry standards, established formulation practices, integration methods for downstream processes, and the corresponding end-use products manufactured by our clients.

    1. Feed Premix Production for Livestock and Aquaculture

    Feed manufacturers utilize DL-Lysine Monohydrochloride as an essential amino acid source to balance nutritional profiles for monogastric animals including pigs, poultry, and certain fish species. Our product supports formulation of compound premixes designed to raise the protein conversion efficiencies, thereby improving animal growth rates and feed utilization. Because these industries operate under regional and global regulations for feed additives, product sourcing, blending accuracy, and traceability remain critical throughout the supply chain.

    Industry compliance standards

    • EU Regulation No 1831/2003 on additives for use in animal nutrition
    • US FDA 21 CFR 582.8156 (Generally Recognized as Safe in animal feeds)
    • China GB/T 18670-2019 (Standards for Feed Grade Lysine)
    • FAMI-QS (Quality and Safety System for Specialty Feed Ingredients)

    Typical usage ratio

    • 0.05% – 0.3% of compound feed mass; exact levels depend on animal species, development stage, and dietary protein sources

    Downstream process integration

    • Addition during the micro-ingredient blending stage before pelletizing or extrusion
    • Regular verification via in-process mixing uniformity and analytical QC checks before bagging and final shipment

    Final product types

    • Poultry feed premixes
    • Swine grower concentrates
    • Fish and shrimp aquaculture feeds
    • Pet food protein supplements

    2. Pharmaceutical Formulation – Parenteral and Oral Nutrition

    DL-Lysine Monohydrochloride serves as a pharmaceutical-grade amino acid in clinical nutrition formulations, especially for patients requiring intravenous or specialized oral amino acid solutions. Hospitals and medical compounding facilities rely on tightly controlled purity and traceability, ensuring compliance with pharmacopeia monographs and GMP requirements. Our production supports sterile-grade sourcing for pharmaceutical integrators preparing both bulk parenteral solutions and enteral products.

    Industry compliance standards

    • United States Pharmacopeia (USP) – Lysine Monohydrochloride Monograph
    • European Pharmacopoeia (Ph. Eur.) 10.0 standard (Lysinum hydrochloridum DL)
    • Chinese Pharmacopoeia (ChP) 2020 Edition
    • Good Manufacturing Practices (GMP) for pharmaceuticals

    Typical usage ratio

    • 0.1 g/100 mL – 0.25 g/100 mL in amino acid infusion solutions, adjusted based on patient age and prescribed total amino acid input

    Downstream process integration

    • Dissolution into sterile water or saline under controlled pH, followed by sterile filtration and aseptic filling
    • Batch records and identity testing performed before release to medical distributors

    Final product types

    • Intravenous total parenteral nutrition (TPN) solutions
    • Oral enteral nutrition drinks
    • Nutritional granules for clinical feeding

    3. Food Fortification – Bakery, Beverage and Dairy Processing

    Industrial food formulators incorporate our material in fine dosing to fortify or replenish lysine content in wheat-based, cereal, and dairy food lines where native lysine is degraded during heat processing. Food engineers follow national food safety requirements, monitoring precise blend uniformity throughout automated batching, to ensure final consumer products meet both nutritional label targets and labeling standards for amino acid enrichment.

    Industry compliance standards

    • Codex Alimentarius – General Standard for Food Additives (GSFA)
    • China GB 2760-2014 (National standard for food additives)
    • EU Regulation (EC) No 1333/2008 on food additives
    • US FDA 21 CFR 182.8994 (Generally Recognized as Safe – Amino Acids)

    Typical usage ratio

    • 0.01% – 0.05% of flour or rehydrated base, determined by lysine deficit analysis in target products

    Downstream process integration

    • Dry blending with flour in silo loading or pre-mix addition during dough mixing for bakery items
    • In-line dosing into UHT dairy or beverage tanks, followed by homogenization
    • Constant monitoring for dosage consistency across shifts

    Final product types

    • Enriched wheat breads and tortillas
    • Ready-to-drink functional beverages
    • High-protein yogurts and dairy desserts
    • Infant cereal mixes

    4. Biotechnological Fermentation Media Optimization

    Celullar agriculture, enzyme, and bio-based chemical producers use DL-Lysine Monohydrochloride as a nitrogen and carbon supplement to optimize cell health and productivity in microbial and mammalian fermentation processes. Formulators fine-tune the rate of supplementation in defined media to support genetic stability and maximize yield, particularly where strains synthesize value-added compounds for pharmaceuticals, food ingredients, or specialty biopolymers.

    Industry compliance standards

    • ISO 9001 (Quality Management Systems for bioprocess facilities)
    • ICH Q7 – Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211 (Pharmaceutical Production Standards)
    • EFSA guidelines for Food Enzyme Production

    Typical usage ratio

    • 0.2 g/L – 3.0 g/L in fermentation broth, tuned according to target strain and product yield targets;

    Downstream process integration

    • Addition as a powder, or after dissolution, to sterile bioreactor media at initial set-up or during fed-batch stages
    • Regular adjustment and monitoring of amino acid depletion rates during culture growth phase

    Final product types

    • Recombinant enzymes for industrial use
    • Biologics and API intermediates
    • Biosynthesized food colorants and additives
    • Fermentation-derived flavors and fragrances

    5. Industrial Synthesis Intermediates for Specialty Chemicals

    Chemists incorporate DL-Lysine Monohydrochloride in multistep organic syntheses, particularly where its bifunctional structure is used to produce advanced polyamides, chelating agents, biodegradable materials, and fine chemical intermediates. Facilities document source integrity and batch-level reaction yields in line with chemical management systems, often as part of custom production campaigns for specialty downstream users.

    Industry compliance standards

    • REACH Registration (EU Chemical Safety)
    • ISO 14001 (Environmental Management for chemical manufacturing)
    • US EPA TSCA regulations (Toxic Substances Control Act)
    • GHS Hazard Communication Standard

    Typical usage ratio

    • Typically 1 – 10 mol% of reaction media; exact proportion determined by downstream synthesis route and desired product molecular weight

    Downstream process integration

    • Direct dissolution into reaction solvent, followed by pH adjustment and staged chemical transformation (e.g. amidation, polymerization)
    • Process monitoring via chromatography or real-time mass spectrometry to confirm intermediate conversion

    Final product types

    • Polyamide engineering resins
    • Biodegradable chelating agents
    • Specialty fine chemical APIs
    • Advanced polymer additives
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    Certification & Compliance
    More Introduction

    DL-Lysine Monohydrochloride: A Close Look from the Production Floor

    Introduction to DL-Lysine Monohydrochloride

    Few materials matter more in feed and food chemistry than amino acids, and lysine consistently stands out among them. In our plants, DL-Lysine Monohydrochloride keeps showing its value in daily operations, project trials, and repeated customer feedback. This compound looks simple on a lab sheet, but every stage of manufacture demands close attention and care. At our site, we don't just pass off white powder as a commodity—the work begins with careful selection of raw materials and controlled synthesis, finishing with a stable, granular or crystalline product that solves genuine industry problems.

    The Model We Produce

    Our most widely produced model, DL-Lysine Monohydrochloride 98.5%, always figures into conversations with nutritionists and technical officers from livestock, aquaculture, and food sectors. We set this concentration as a standard after years working with various blending and extruding lines. Customer feedback has consistently shown this level of purity integrates smoothly into both compound feeds and premixes. Unlike arbitrary grade labels or repackaged products of less certain origin, this product model comes off our lines subject to fourteen separate quality checks before it leaves the facility. The ability to maintain near-perfect microcrystal range with minimal dust has proved just as valuable as chemical content itself—production lines rarely slow due to caking or flow issues when they use straight-from-source lysine.

    Why DL-Lysine Matters—In the Field and on the Farm

    Few sites operate in isolation nowadays. Feed mills, integrated poultry operations, and ruminant nutrition formulators spend much of their day solving calculation puzzles: how to reach protein targets, how to minimize waste, and how to ensure yield. From years spent troubleshooting with technical teams, we know that synthetic lysine bridges the gap whenever locally sourced protein supplies run short or grow unpredictable in quality. DL-Lysine Monohydrochloride brings a guaranteed lysine source, free of common allergens, animal byproducts, or variable crop residues found in raw feedstuffs.

    By using this amino acid, premixer plants boost crude protein utilization rates in broilers, fish, and pigs. In some of our testing, it shaved input costs up to 5% by allowing feed formulas to swap out portions of expensive soya or canola meals without performance loss. Nitrogen reduction often sits high on the agenda for integrated producers—less crude protein in the diet, made possible by accurate lysine supply, leads to less nitrogen excreted in manure. In heavily regulated regions, this makes a direct difference to environmental compliance and farm economics.

    For food processors, particularly those developing specialized or functional foods, this chemical offers a route to label-friendly formulation. The origin and traceability of our lysine supports cleaner ingredient lists, and no animal proteins or GM inputs enter the process. Reports from long-standing customers show that product consistency and granular control prevent batch-to-batch variation—a real pain point for those with strict regulatory or third-party auditing.

    Understanding the Specifications

    Of all the topics that come up in customer discussions, clarity around specifications matters most. Here, we see demand centering not just on purity, but also on physical profile, solubility, and shelf life. Our production process, using precisely controlled fermentation and subsequent hydrochloride neutralization, produces a DL-Lysine Monohydrochloride that is over 98.5% pure. The remaining fraction mainly contains bound moisture and a trace of inert mineral residue, no unidentified organics.

    Samples drawn from each batch go through rigorous on-site tests: high-performance liquid chromatography checks lysine ratio and purity, while particle size analysis ensures easy mixing into vitamin-mineral blends or direct pelleting. Standard moisture level remains at 0.2% or below—a vital number, since excess moisture often leads to caking that blocks feeders and silos across the supply chain. From discussions with quality teams at leading feed companies, we know this small difference saves hours of downtime and maintenance headaches.

    Our granule type supports easy handling in automated feed production, eliminating the airborne dust that often causes problems for operators with respiratory sensitivities. We avoid using anti-caking additives or flow agents that could raise red flags in food safety audits, keeping every shipment compliant with ISO and HACCP expectations. Customers often cite the certainty that comes from this approach; repeat assays give them the same number today as six months ago, which their compliance departments recognize on every test certificate.

    A key point of technical debate deals with the isomer form. DL-Lysine Monohydrochloride presents both D and L enantiomers, with the L form matching the biological requirements of animals. In practical experience, we have found that using this mixture offers reliable performance in monogastric diets, given the ease with which most species convert the small amount of D isomer. For ultra-high-performance applications, such as certain food supplements, some buyers may choose pure L-lysine, though this comes at a cost and supply availability that the blended variant often avoids.

    How DL-Lysine Monohydrochloride Stacks Up Against Other Lysine Types

    It’s tempting to think lysine is just lysine. On the floor, though, choices between different salts, concentrations, and sources change real-world outcomes. DL-Lysine Monohydrochloride stands as the hydrochloride salt of lysine obtained by reacting the base with hydrochloric acid, then drying to a stable state. Lysine sulfate and lysine base are alternative products on the market, but their application and characteristics differ noticeably.

    Compared with lysine base, our product brings several practical advantages. The hydrochloride form offers improved stability, resisting atmospheric moisture pick-up during shipping and storage. Lysine base, by contrast, tends to absorb moisture readily, which can cause clumping in bulk silos and bridge formation in dosing equipment. Over the years, operators at customer feed mills have noted that switching to our monohydrochloride variant reduced costly downtime and avoided repeated cleaning cycles.

    Lysine sulfate is a byproduct-based alternative, generally with lower purity and more variable physical properties. Several inquiries come in every month asking why our feedspec DL-Lysine Monohydrochloride price point seems higher than sulfate grades. The answer lies in the guaranteed lysine content and hygiene standards involved in the full chemical synthesis route. Lysine sulfate might suit certain bulk-minimizing operations or less-regulated environments, but for applications demanding precision feeding, guaranteed digestibility, and traceable ingredient chains, DL-Lysine Monohydrochloride proves more reliable and cost-effective over an annual consumption cycle.

    In some markets, particularly in high-tech or R&D settings, we meet requests for pure L-lysine hydrochloride. We manufacture this grade for pharmaceutical and infant nutrition applications, but it comes at a higher cost per ton, with stricter limits on isomer purity. Years of feedback and market usage confirm that for mainstream animal feed, aquafeed, and functional food applications, DL-Lysine Monohydrochloride offers a dependable, well-balanced solution.

    Manufacturing Insights: What It Takes to Get it Right

    From start to finish, producing DL-Lysine Monohydrochloride involves a tightly controlled cascade of steps that tolerates little margin for error. Having spent years in this industry, we know that process optimization leads to consistent output more than high-tech add-ons ever do. The first step brings together core feedstocks—often glucose and ammonia—into fermentation tanks seeded with specialized microbial cultures. Strain selection and precise control of tank conditions matter more than any trick in the book. Any deviation drops the output yield or generates unwanted byproducts, as our shift managers quickly spot during routine process checks.

    After the initial broth ferments, a series of downstream purifications start. We clarify the lysine-rich solution, filter out fine solids and then neutralize the lysine with high-purity hydrochloric acid. Controlled cooling and gradual crystallization yield the salt as a dense, free-flowing granular material. We continually refine this stage based on customer feedback on solubility, flow, and handling. An experienced eye can spot the difference between batches that spent a few too many hours drying versus those stopped at just the right humidity.

    Packing and shipping practices often influence the delivered product as much as upstream chemistry. In our early years, customers sometimes received slightly compacted bags or found a telltale ammonia odor from traces of unremoved byproducts. Since then, robust in-line quality control and thorough final vacuum packing have nearly eliminated these complaints. Reliable packaging means our customers can stock up for seasonal production peaks, knowing storage quality won’t slip even after months in the warehouse.

    Usage in Feeding Systems and Food Applications

    Most of our output feeds directly into farm nutrition programs. Procurement officers, veterinary nutritionists, and operations managers appreciate a supplementary lysine source that doesn't leave their ration balancing to guesswork. In poultry, swine, and aquatic feed systems, our DL-Lysine Monohydrochloride goes straight into feed mixers and pellet presses, supporting lean growth rates and improved feed conversion. Years working alongside feed producers have shown us that even small formulation errors—half a percent too low or too high—can impact feed efficiency or animal health. Consistency in lysine concentration and moisture proves vital to avoid such costly deviations.

    Aquafeed formulators, particularly in regions with fluctuating fishmeal prices, use this product as an anchor for protein specification. Controlled release improves digestibility and reduces excretion losses, making it easier for operators to hit performance and environmental benchmarks. We’ve supported trials where our lysine enabled diets to reach precise amino acid balance—even as raw material profiles shifted between batches of byproduct fishmeal or plant meals.

    The food sector relies on our material for specialty products—fortified pastas, baked goods, baby foods, and nutraceutical blends all use lysine fortification to address protein gaps or meet dietary regulations. Having worked with R&D teams in major food groups, we hear repeated requests for certificates of origin, allergen statements, and non-GM status. Our processes and traceability records fully support these needs, which has allowed long-term partnerships with companies targeting European and North American clean-label markets.

    Traceability and Sustainability Considerations

    Traceability requests have become routine in the last ten years. Auditors, nutritionists, and compliance officers want a full view across their ingredient chain. We give them not just batch numbers but origin lot detail for every shipment of DL-Lysine Monohydrochloride. After several food safety scares across the industry, trust grows where regular paperwork and open communication lines are in place. Our lab systems connect directly with production records, publishing verified assay results for customer assurance.

    Sustainability, too, moves beyond buzzword status in real-world conversations. From our own benchmarking efforts, DL-Lysine Monohydrochloride production yields a modest carbon footprint compared to protein extraction from soya or animal sources. Fermentation relies on renewable carbohydrate sources—mainly corn or wheat—and new microbial strains continue to shave energy input and effluent generation. We collaborate with feed and food partners to track LCA (life cycle assessment) data on every major input and output. While nobody in this space achieves zero waste, ongoing energy recovery, water reuse, and local feedstock sourcing remain priorities.

    By communicating process improvements openly, from fermentation upgrades to better packaging technologies, we foster customer trust and regulatory compliance. This spirit of openness extends to third-party audits, routine certifications, and maintaining direct dialogue with industry working groups on food and feed safety.

    Logistics and Handling Observations from Experience

    Every year, our logistics team moves thousands of tons of DL-Lysine Monohydrochloride across continents. The difference between theory and practice shows up in the details: container sweating, loading angles, warehouse temperature spikes, and pallet wrapping matter as much as what's inside the bag. Our supply partners worked with us to develop reinforced packaging and moisture-variable sealing, preventing any chance of powder loss or contamination.

    Clients over the years have asked about shelf life and optimal storage. We advise storing in a cool, dry, and well-ventilated setting to maximize the guaranteed shelf life of at least two years from production. Direct contact with unsealed air, high humidity, or improper stacking can degrade appearance and mixability, though lysine itself remains stable in its hydrochloride form. Some older warehouses with outdated climate controls once reported caking or discoloration; upgraded storage and shipment protocols quickly eliminated these issues, minimizing inventory loss.

    Handling on automated feed lines or blending systems stresses product consistency. Our granule sizing and low moisture profile deliver predictable flow through screw feeders and auger systems, backed up by customer maintenance logs reporting reduced downtime. In addition, rigorous bag and bulk truck cleaning prevent cross-contamination with other micro-ingredients, underscoring our investment in food safety.

    Market Trends and Challenges: A Manufacturer’s Perspective

    Global trade and regulatory environments never stand still. Feed prices bounce with grain futures; livestock producers pivot their feeding strategies when disease breaks out on another continent. We stay involved in working groups and technical committees, learning where the demands are heading. Recent years brought greater calls for traceable, non-GM lysine sources with categorically low impurity levels.

    Geopolitical volatility or energy price hikes sometimes pressure raw material sourcing. Our production managers have learned hard lessons about keeping diversified supply chains and forward-planned inventories. These measures insulate both us and our customers from the worst swings, keeping product available and affordable when supply chains break down elsewhere.

    Competitors from all regions offer their own formulations, but in direct field comparisons, purity, solubility, and regulatory compliance standards set our production apart. Customer procurement officers value transparent documentation—we provide detailed assay, origin, and allergen reports with every shipment. Users in the EU, North America, and east Asia regularly conduct spot checks and audits of our shipments, reinforcing our focus on compliance, safety, and long-term trust.

    Collaborating with Customers to Develop Solutions

    One of the main strengths of our approach comes from working directly with customer teams. Feed mills and food processors call us in to troubleshoot flow issues, adapt blending strategies, and even test new grades on-site. Responsive technical teams adjust granulation, moisture, and packaging for specific blending or pelleting needs, based directly on recurrent feedback. Recent projects involved custom particle sizing for micro-pellet aquafeeds and low-dust formulations for automated mill lines. The willingness to iterate on small details ensures every batch of DL-Lysine Monohydrochloride fits into the latest processing systems.

    Our field service teams often visit mills, offering side-by-side analysis of production runs, nutrient recovery, and final feed output. A few hours spent on the floor with operators reveals the real-life impact of modest source changes. These insights translate into process improvements back in the plant, streamlining not just production, but logistics, handling, and final user value.

    We gather customer feedback not only for compliance but also to push our own internal standards. Continuous improvement keeps the product relevant as both animal nutrition science and consumer expectations evolve. As regulatory frameworks grow stricter and traceability standards broaden, partnership and communication become the basis of all real progress in this sector.

    Concluding Thoughts on DL-Lysine Monohydrochloride’s Role Today

    After decades of production and partnership, DL-Lysine Monohydrochloride earns its reputation on the strength of science, daily diligence, and steady dialogue between factory and field. It may not draw headlines, but its contribution to global food security, animal nutrition, and responsible procurement remains clear each day. Our experience shows that building trust with users, refining production details based on actual feedback, and embracing openness around safety and sustainability produce superior results. As always, we base our work on solid technical practice and close customer support, ensuring that each shipment delivers on both specification and expectation.