Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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DL-Lysine

    • Product Name DL-Lysine
    • Alias Lysine
    • Einecs 210-514-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    225647

    Chemical Name DL-Lysine
    Molecular Formula C6H14N2O2
    Molar Mass 146.19 g/mol
    Appearance White crystalline powder
    Solubility In Water Soluble
    Melting Point 224 °C (dec.)
    Cas Number 70-54-2
    Ph Value 5.0-6.0 (1% solution)
    Isomeric Form Racemic mixture (DL-form)
    Odor Odorless
    Storage Conditions Store in a cool, dry place
    Usage Nutritional supplement

    As an accredited DL-Lysine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g white powder packed in a sealed, moisture-resistant plastic bottle with a screw cap, labeled "DL-Lysine, Analytical Grade".
    Shipping DL-Lysine is shipped in tightly sealed containers, protected from moisture and contamination. It should be transported in accordance with relevant safety regulations, avoiding extreme temperatures, heat, or direct sunlight. Proper labeling and documentation are required. Handle with care to prevent physical damage and ensure compliance with chemical safety guidelines during transit.
    Storage DL-Lysine should be stored in a tightly sealed container, protected from moisture and direct sunlight. Keep it in a cool, dry, and well-ventilated area, ideally at room temperature (15-25°C). Avoid exposure to strong acids, bases, and oxidizing agents. Ensure proper labeling and prevent contamination by handling with clean, dry equipment and protective gloves.
    Application of DL-Lysine

    Applications of DL-Lysine in Industrial Manufacturing

    As a direct manufacturer and global supplier of DL-Lysine, we support critical industrial sectors by providing high-purity material suitable for precise formulation needs. The following industrial application scenarios reflect core markets where our DL-Lysine is integrated as a key functional ingredient, addressing strict regulatory requirements and production demands in each downstream sector.

    1. Animal Nutrition Premix Production

    Compound feed and premix manufacturers in the animal nutrition industry utilize DL-Lysine to enhance essential amino acid profiles for swine, poultry, and aquatic species, compensating for plant-based protein limitations. Feed formulators apply precise micro-dosing controls to maintain nutritional targets and comply with traceability protocols, particularly in high-performance and specialty growth diets where amino acid balance critically impacts feed conversion rates and overall productivity.

    Industry compliance standards

    • FAMI-QS (Quality and Safety System for Specialty Feed Ingredients and their Mixtures)
    • EU Regulation (EC) No 1831/2003 on feed additives
    • GB/T 18823-2002 (Chinese National Standard for feed grade lysine)
    • FDA CFR Title 21, Part 573: Food Additives Permitted in Feed and Drinking Water of Animals (US)

    Typical usage ratio

    • 0.2% – 0.9% of total feed weight for swine and poultry feed premixes
    • Level adjusted based on basal feed protein analysis, species growth stage, and production performance data

    Downstream process integration

    • Micro-ingredient batching prior to main mixing and granulation
    • Direct dosing into liquid or powdered premixes, followed by homogenization
    • Integrated into computerized batch control systems for recipe traceability

    Final product types

    • Compound feed (for swine, broilers, layers, and aquaculture)
    • Vitamin–amino acid premixes
    • Medicated feeds and balanced rations

    2. Food Fortification in Bakery Production

    Food industry processors fortify wheat-based bakery goods with DL-Lysine to address the natural lysine deficiency of cereal proteins. Commercial bakeries apply controlled dosing in dough mixing phases to increase total protein nutritional value in breads, biscuits, and crackers, targeting populations with specific protein intake recommendations and optimizing labeling claims for enriched foods under regional standards.

    Industry compliance standards

    • Codex Alimentarius (CODEX STAN 192-1995, General Standard for Food Additives)
    • GB 2760-2014 (Chinese National Standard for Food Additives)
    • EFSA food additive evaluation (EU regulation EC 1333/2008)
    • FDA GRAS Notification (US for amino acids in foods)

    Typical usage ratio

    • 150–300 mg per 100 g flour (0.15%–0.3%)
    • Adjusted to protein digestibility score and local nutritional regulations

    Downstream process integration

    • Direct addition to flour or dough during automated mixing
    • In-line quality control for blend uniformity before proofing and baking

    Final product types

    • Fortified bakery bread (sandwich loaves, rolls)
    • Enriched biscuits and crackers
    • Protein-enhanced pasta and noodles

    3. Cell Culture and Biotechnology Fermentation Media

    Bioprocessing companies and research laboratories formulate complex cell culture media and microbial fermentation broths using DL-Lysine as a primary amino acid source to promote cell growth and protein synthesis. Industrial-scale media manufacturing demands precise composition tracking, particularly in regulated therapeutic protein, enzyme, and vaccine production where batch-to-batch reproducibility and contamination control are essential.

    Industry compliance standards

    • USP <1043> Ancillary Materials for Cell, Gene, and Tissue-Engineered Products (United States Pharmacopeia)
    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • ISO 13408-1: Aseptic Processing of Health Care Products
    • Chinese Pharmacopoeia (for cell culture reagents)

    Typical usage ratio

    • 20–80 mg/L in mammalian or microbial cell culture media
    • Levels optimized by cell line requirements, target protein yield, and downstream purification protocols

    Downstream process integration

    • Weighing and dissolution during initial preparation of media solutions
    • Sterile filtration and containerization before transfer to bioreactors

    Final product types

    • Ready-to-use cell culture media (liquid and powder)
    • Bioprocess fermentation broths for industrial enzyme and recombinant protein production
    • Therapeutic antibody and vaccine manufacturing intermediates

    4. Pharmaceutical Synthesis Intermediates

    The pharmaceutical manufacturing sector uses DL-Lysine both as a key reactant and a chiral resolving agent in the synthesis of APIs, peptide drugs, and pharmaceutical-grade intermediates. Precision in molecular purity, solubility control, and impurity profiling is critical to meet GMP validation and regulatory submissions, especially in high-volume batch production environments for small molecule and biologics sectors.

    Industry compliance standards

    • USP/NF monograph for amino acid pharmaceutical grade
    • ICH Q3A-Q3C guidelines for Impurities in New Drug Substances and Products
    • EU GMP Part II: Basic Requirements for Active Substances
    • Chinese Pharmacopoeia (ChP) amino acid standards

    Typical usage ratio

    • Varies from 0.5–2.0 equivalents as a reactant or 1–10% w/w as a chiral auxiliary depending on synthetic scheme
    • Controlled by stoichiometry of reaction and desired enantiomeric excess

    Downstream process integration

    • Charged during initial stage of chemical synthesis or peptide assembly
    • Purification and crystallization post-reaction, followed by GMP-grade quality testing

    Final product types

    • API intermediates (e.g., specialty amino acid derivatives)
    • Short-chain peptide drugs
    • Chiral separation products for drug development

    5. Nutraceuticals and Dietary Supplements Manufacturing

    Producers of sports nutrition and wellness supplements incorporate DL-Lysine to supply essential amino acid content in finished dietary tablets, capsules, and ready-mix powders. Manufacturers must manage ingredient integrity, allergen cross-contamination, and label accuracy across large-scale tablet presses and encapsulation lines, complying with nutritional regulatory declarations and accepted pharmacopeia purity limits for oral intake products.

    Industry compliance standards

    • FDA 21 CFR Part 111: Current Good Manufacturing Practice (cGMP) for Dietary Supplements
    • EFSA guidance on food supplements (Directive 2002/46/EC)
    • USP dietary supplement compendia
    • NSF/ANSI 173: Dietary Supplements Standard

    Typical usage ratio

    • 300–1000 mg per daily dose in tablets, capsules, or powder blends
    • Adjusted by product format, target consumer group, and dietary allowance labeling

    Downstream process integration

    • Dry blending and granulation prior to tablet compression or encapsulation
    • In-process quality sampling and final weight checks for uniformity

    Final product types

    • Nutritional supplement tablets (single-ingredient or multi-amino acid)
    • Athletic performance powder mixes
    • Capsule-based wellness supplements
    Free Quote

    Competitive DL-Lysine prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

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    Certification & Compliance
    More Introduction

    DL-Lysine: Industry-Grade Innovation Rooted in Manufacturing Experience

    Practical Value of DL-Lysine in Chemical Production

    DL-Lysine holds a unique position among amino acids we manufacture, mainly for its role beyond nutrition. In our own process lines, producing DL-Lysine in granular and powder forms has given us practical insights into its versatility. We see customers use it both in industrial fermentation and as an intermediate, where its stable profile gives formulators better control over outcomes. Over the years, we've worked out kinks in moisture control and crystallization, which means product consistency holds up during shipping and storage. Moisture on the plant floor doesn't mess with its physical integrity, meaning customers avoid unnecessary batch losses.

    Specifications Shaped by Real-World Demands

    Our DL-Lysine comes with a purity above 98.5%, measured by titration techniques, which we've refined after long rounds of QA tweaks. Particle size matters because mixes must flow well in both automated feeders and manual operations. In response, our plant lets us produce both fine and coarse specifications, minimizing dust for handlers while keeping dispersibility high. Our QA staff checks for residual solvents, heavy metals, and microbial counts daily. Not every spec aligns with every customer, but feedback directly influences our continuous tweaks. For feed, beverage, and technical use, we tailor final rinse cycles and filtration steps. Sodium and chloride levels stay within targeted ranges to avoid interference with downstream chemistry, based on feedback from industrial protein hydrolysate users.

    Model Details and Batch Consistency

    Years in large-batch manufacture taught us that reliable models start with tight fermentation control and good downstream separation. Our main model, DL-Lysine HCl, comes off the line after several quality gates. Filtration, concentration, and drying run under automated protocols based on the composition data collected in real time. This way, batch-to-batch variance drops below industry error margins—a claim we've been tested on by third-party auditors. Granule size and density end up predictable, so companies blending into premixes can calculate load and solubility profiles in advance. Unlike many generic product streams, we don't rely on spot purchases of raw lysine; our backward integration for raw materials helps minimize outside contaminants that can compromise both shelf life and downstream yield.

    Real Application Stories: Formulators’ Testimony

    Working closely with technical directors at several compounds manufacturers, we noticed one recurring outcome: consistency in DL-Lysine purity reduced their troubleshooting hours during scale-up. One customer, shifting from feed-grade L-Lysine to our DL version, found that by managing both the D- and L- isomers, enzymatic reactivity dropped—sometimes a necessary step for chemical synthesis applications. Batch note archives from our quality team show that over 90% of complaints filed on third-party products stemmed from batch impurity or unexpected isomer ratios. Our in-process corrections, as tracked via electronic batch records, have brought that number close to zero for DL-Lysine. This highlights why sourcing directly from a producer changes daily outcomes for downstream users.

    Key Differences: DL-Lysine vs. L-Lysine and Synthesized Alternatives

    DL-Lysine differs from single-isomer L-Lysine in practical chemistry terms. We make ours by racemizing the alpha carbon during synthesis, blending both D- and L- isomers. That opens up different synthetic reaction routes for certain chemical intermediates. In peptide synthesis, some want only L-Lysine for bioactivity; others find the mixed isomer version better for creating less enzymatically active derivatives. Synthetic alternatives, especially ones produced through fermentation only, often struggle with batch-to-batch drift in isomer content, sometimes due to uncontrolled fermentation variables. That means inconsistent end products for users downstream. Our manufacturing uses a hybrid of controlled fermentation and chemical racemization, anchored by instrument monitoring in real time, which tightens that window. For corrosion inhibitor blends, a key application among our technical-grade buyers, the less-reactive nature of the racemic mixture cuts down on unwanted side reactions, something customers flagged as major cost points with other options.

    Quality Assurance Embedded in Each Batch

    Manufacturing at scale means more than just turning raw inputs into a white crystalline powder. Every week, our production team meets to review analytic trends from the latest batches, comparing chromatography results and microbial activity tests. We deal directly with shipping, so we control storage conditions after packing and can guarantee shelf life under stated conditions. Unlike brokers who simply repack, our records show origin and traceability back to individual fermenters and crystallizers. Regulatory audits, especially from international buyers, demand true traceability. Our systems hold every analytical report, supporting compliance and quick responses to any batch issue. Years of exporting mean our documentation matches requirements from authorities in various regions—whether it’s a certificate of analysis, microbial safety data, or proof of radioactive absence for sensitive technical uses.

    Manufacturing Process: Experience Drives Optimization

    Making DL-Lysine cost-effectively means constant process improvement. We have learned that fermentation yield takes a hit if minor trace metals aren't balanced. Early batches ran with variable aeration; over time, our oxygen control system, installed after demands from technical buyers, steadied final titers. Downstream, where the racemization step merges with product isolation, we risk introducing unwanted byproducts if pH or temperature shift too far. By switching to continuous monitoring, enforced by our senior process engineers, side-product markers dropped beneath detectable levels. The process shifts from raw substrate, through bioreactor, filtration, racemization, and crystallization, into drying and milling—all with human oversight at every step. That’s one reason our finished product meets batch reproducibility requirements for both technical and nutraceutical clients.

    Challenges We Solved in Scaling Up DL-Lysine

    Scaling DL-Lysine manufacture doesn’t just mean ramping up bioreactor volume. We found, launching new reactors, that heat management becomes critical; temperature spikes flattened crystalline yield and produced unwanted byproducts, which required months to troubleshoot. Persistent issues with dustiness in fine-powder grades led us, after direct feedback from feeding operators, to modify our drying stage and change bagging configurations. Local humidity swings called for extra investments in environmental controls, but downtime plummeted and fewer batches went off-spec as a result. Every troubleshooting episode sharpened our knowledge, and technical improvements made since have trickled down to shorter delivery times and higher batch quality.

    Economic Perspectives: Supply Chain, Pricing, and Sustainability

    As actual manufacturers, we're exposed to market swings in petroleum feedstocks and agricultural raw materials. The DL-Lysine price index at our plant reacts to these trends, but we buffer volatility by maintaining extended supply contracts. Our procurement team sources from domestic and international growers, after running wet chemistry checks on every lot. Volatility still seeps through, so we set price hedges where possible and communicate transparently with regular buyers. Sustainability enters into every step; we’ve retrofitted our waste treatment to recover ammonia, slash emissions, and reduce water consumption. We publish annual data on energy use per ton of DL-Lysine output, and our recent upgrades pushed this index down by 15% compared to three years ago. Downstream users who audit us have remarked that direct manufacturer sourcing makes environmental due diligence easier, since all records originate at our site. Steady pricing, transparent audits, and the sustainability track set our products apart in large-volume industrial supply.

    DL-Lysine in Downstream Use: Innovation and Application Feedback

    DL-Lysine continues to carve out niches in industrial chemistry where both enantiomers perform distinct roles. Synthesizing specialty polymers, surfactant builders, and cross-linking agents requires predictable chemical properties. Through participating in customer process development, we’ve seen where our product supports new compound generation—sometimes as a chain extender, sometimes as a precursor for further derivatization. Technical teams from adhesive formulators reviewed our batch records before adopting our DL-Lysine into their plant trials. Feedback has led us to tweak our finishing conditions, for example, dropping particle size below a certain threshold so users avoid re-milling. Transparency and customizability stand as key reasons chemical innovation teams return to us for more than just bulk supply.

    Comparisons with Competing Ingredient Streams

    Not all lysine sources deliver the same results. Products supplied by traders, particularly in global bulk markets, fail under strict QC when byproduct content or untraceable impurities creep above standards. We've spent time analyzing competitor samples in our own quality labs: high-ash residues, off-odor, and variable water content sometimes turn up in samples from indirect sellers. By keeping our fermenters and separation lines internal, we've nearly eliminated the risk of unknown contaminants, keeping our customers' process outputs reliable over time. Real-world comparisons, compiled from formulation troubleshooting logs, point to fewer blend failures with direct manufacturer sources of DL-Lysine. Many end users switched to our batches after seeing too many quality swings from gray-market purchases.

    Safety, Handling, and Documentation Practices

    On our production floors, safety starts long before finished powder reaches a drum. Each operator trains yearly on handling procedures, especially around dust control and bulk movement. We log each incident, no matter how minor, so that improvements snowball into safer workspaces. Our staff works closely with environmental health teams to monitor air and effluent, ensuring levels stay well within published guidelines. Customers sometimes request extra documentation, such as suitability for certain allergens or origin tracing for specialized applications, which we provide without delay because records remain in-house—not scattered across third-party databases. Longstanding relationships with transporters mean drums and bags leave our site with real-time tracking codes and complete documentation, smoothing their own audits down the line.

    Ongoing Innovation: Working with Formulators and Industry Partners

    Collaborative development forms part of our daily routine. We open our pilot labs for customer trials, allowing companies to test new formulations with freshly produced DL-Lysine. Raw material variations can skew downstream results; sharing samples from various production runs with customers lets them plan ahead and pinpoint optimal specs. Regular site audits by industry partners have kept our engineering team sharp, as every feedback point prompts process or QC improvements. By building partnerships, both sides speed up innovation—not just for the sake of keeping up, but because the next efficiency gain supports everyone’s bottom line. Years of these shared efforts have impacted not only the performance of DL-Lysine in formulated products but also the total cost and environmental burden in actual use.

    Regulatory Experience: Export Certification and Cross-Border Supply

    Supplying DL-Lysine into international markets requires a clear view of shifting regulatory landscapes. We train our export staff to understand different requirements, whether it’s for import permits, purity statements, or special technical certifications. Each consignment ships with a dossier that meets the importing country’s specs, based on language, analytical method, or permissible contaminants. Being the point of origin, we maintain detailed batch records and analytical data that auditors require and that speeds up customs clearance. Some industrial buyers have relied on our regulatory team for updates before new region-specific laws take effect, minimizing the risk of stranded inventory. Documentation isn’t handled by outside agents; our own chemists and compliance officers handle it internally, so answers stay accurate and timely. Customers scaling up exports find our direct support decreases risk and speeds up international project launches.

    Sustained Value Through Reliability and Direct Engagement

    DL-Lysine remains a staple across basic industrial synthesis and technical applications, but reliability is what locks in value. Directly operating every leg from fermentation to shipping, we keep a close eye on every variable. Customers using our product often cite stable supply and fast responses to technical tweaks as reasons for sticking with a direct manufacturer. The difference is more than paperwork—it's about the daily reality of keeping processes running on time, inventories within spec, and new development programs moving without disruption. Having real authority over production means we minimize downtime and batch variability, benefitting everyone in the value chain.

    Shaping Future Directions in DL-Lysine Manufacture

    Every year, technical improvements and real-world feedback shift our approach to making and delivering DL-Lysine. Whether it's refining separation techniques to extract purer product or rethinking packaging to cut waste, end-user experience drives us forward. The growth of green chemistry applications asks for higher traceability and tighter specs, and we gear ongoing upgrades to meet these demands. As technical markets keep evolving, direct partnership with actual producers makes the difference between getting by and building robust new products. We see our role not just as suppliers but as long-term partners, supporting innovation with real, hands-on chemical manufacturing expertise.