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DL-Glutamic Acid

    • Product Name DL-Glutamic Acid
    • Alias glutamic-acid
    • Einecs 210-522-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    250158

    Chemical Name DL-Glutamic Acid
    Molecular Formula C5H9NO4
    Molar Mass 147.13 g/mol
    Cas Number 617-65-2
    Appearance White crystalline powder
    Solubility In Water Soluble
    Melting Point 199 °C (decomposes)
    Optical Activity Racemic mixture (DL-form)
    Ph Value About 3.2 (1% solution)
    Storage Conditions Store in a cool, dry place
    Uses Laboratory reagent, biochemical research
    Synonyms 2-Aminopentanedioic acid, racemic glutamic acid

    As an accredited DL-Glutamic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for DL-Glutamic Acid comes in a sealed 500g white plastic bottle, labeled with product details, batch number, and safety information.
    Shipping DL-Glutamic Acid is shipped in sealed, moisture-proof containers to prevent contamination and degradation. Packages are clearly labeled with chemical identification and hazard information. During transport, it is kept in cool, dry conditions, away from incompatible substances. Handling complies with safety regulations for non-hazardous solid chemicals.
    Storage DL-Glutamic Acid should be stored in a tightly closed container in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizing agents. Protect it from moisture and direct sunlight. Store at room temperature to ensure stability. Always follow standard laboratory practices and consult the Safety Data Sheet (SDS) for specific storage and handling instructions.
    Application of DL-Glutamic Acid

    Applications of DL-Glutamic Acid in Industrial Manufacturing

    DL-Glutamic Acid serves multiple roles across chemical and biochemical supply chains, supporting formulators in several transformation industries. As a direct factory manufacturer, we follow specific quality systems and supply standards, ensuring stable input for key downstream applications.

    1. Amino Acid-Based Feed Additives

    Animal nutrition manufacturers use DL-Glutamic Acid as an essential component in compound feed for poultry, swine, and aquaculture. The compound provides a supplemental nitrogen and carbon source, particularly in starter and grower feed premixes. Production plants implement rigorous controls to ensure accurate dosage and integration into vitamin and amino acid complexes, maintaining nutritional balance and digestibility through extrusion or pelleting steps.

    Industry compliance standards

    • GB/T 26738-2011 (Feed Additives – Glutamic Acid standard, China)
    • European Feed Additives Register (Regulation (EC) No 1831/2003)
    • FSMA (21 CFR 225, US Food Safety Modernization Act for feed)
    • ISO 22000 Feed Manufacturing Quality Management Systems

    Typical usage ratio

    • 0.05%–0.20% by weight in complete feed, optimized based on protein adequacy; increased supplementation for lysine-enhanced diets.

    Downstream process integration

    • Premix formulation and blending before pelleting or extrusion.
    • Batch scale weighing with minor ingredient automation to prevent segregation loss.
    • QC sampling after thermal processing to verify amino acid recovery.

    Final product types

    • Poultry starter and grower compound feed
    • Fish and shrimp aquaculture feed granules
    • Swine prestarter and nursery feeds
    • Ruminant protein supplement blocks

    2. Monosodium Glutamate (MSG) Synthesis

    DL-Glutamic Acid is a primary precursor in the industrial production of MSG via enzymatic or catalytic conversion. Food and seasoning manufacturers convert the material through neutralization and crystallization, employing food-grade controls at each stage. The process demands stringent impurity management to meet global food additive certification, with final crystallization stages producing a high-purity, food-safe seasoning ingredient.

    Industry compliance standards

    • FCC (Food Chemicals Codex) for MSG
    • E621 (EU food additive code)
    • GB 8967-2016 (PRC national food additive standard)
    • 21 CFR 172.320 (US FDA regulation for flavor enhancers)

    Typical usage ratio

    • Stoichiometric conversion: 1.0 kg DL-Glutamic Acid yields approximately 1.2 kg MSG (including neutralizer addition). Reactor and process losses may require 1–3% excess input for process control.

    Downstream process integration

    • Direct feeding into neutralization reactors with sodium carbonate or caustic soda.
    • Clarification, filtration, and successive crystal precipitation.
    • Standardized drying and sieving prior to packaging.

    Final product types

    • Monosodium glutamate food seasoning
    • Compound flavor enhancer blends
    • Instant soup/base flavor powders
    • Processed snack and convenience meal flavorings

    3. Polyglutamic Acid Biopolymer Manufacturing

    Biotech and material science companies use DL-Glutamic Acid as a fermentation substrate for polyglutamic acid (PGA) production. Microbial fermentation processes employ select Bacillus strains capable of direct conversion, with precise substrate quality and feeding rate control critical for polymer yield and molecular-weight targeting. The input ratio and purity directly impact water solubility and film-forming behavior in downstream agro, cosmetic, and medical material applications.

    Industry compliance standards

    • ISO 9001 Quality Management for Biopolymer Processing
    • REACH (EU Chemicals Registration for polymer products)
    • JECFA specifications for food-grade polyglutamic acid where applicable
    • Chinese Pharmacopoeia for medical-grade PGA (where used in wound dressings)

    Typical usage ratio

    • 35–60 g/L fermentation substrate in fed-batch or continuous fermentation, optimized for Bacillus strains and productivity targets. Adjusted for nitrogen and mineral co-supplementation.

    Downstream process integration

    • Direct dissolution into fermentation media in seed tanks, followed by inoculation.
    • Monitoring and adjustment of substrate feed rate to maintain cell health and maximize productivity.
    • Post-fermentation, integrated recovery via precipitation or ultrafiltration.

    Final product types

    • Superabsorbent hydrogels for medical and hygiene
    • Slow-release fertilizer coatings
    • Plant growth biostimulant concentrates
    • Food-grade film-forming agents and thickeners

    4. Pharmaceutical Intermediate for Glutamate Drugs

    DL-Glutamic Acid functions as a chiral precursor and reactant in the pharmaceutical synthesis of several amino acid-based drug substances. GMP-compliant API producers use it in the route to L-glutamine, as well as for chemical modification in anticonvulsant APIs and parenteral nutrition solutions. Strict traceability and validated purification steps are required to satisfy pharmacopeial monographs and regulatory documentation throughout synthesis and final formulation.

    Industry compliance standards

    • USP-NF Monograph for Glutamic Acid
    • European Pharmacopoeia (Ph. Eur.) for amino acid APIs
    • cGMP (ICH Q7) for API manufacturing
    • Chinese Pharmacopoeia (ChP) standards for injectable grade

    Typical usage ratio

    • Stoichiometric or slight molar excess depending on reaction route (1.0–1.2 mol per mol target API). Adjusted according to downstream purification losses or conversion efficiency.

    Downstream process integration

    • Input at initial API synthesis reaction or amino acid modification step.
    • Acid/base and resolution steps under validated batch control.
    • Purification via crystallization, chromatography, or preparative HPLC according to API grade.

    Final product types

    • L-Glutamine for intravenous and nutrition therapy
    • Glutamate-based anticonvulsant active ingredients
    • Combinational parenteral nutrition solutions
    • Bulk excipients for hospital pharmacy compounding

    5. Chelating Agent for Detergent and Water Treatment Formulations

    Chemical formulators use DL-Glutamic Acid as a base material in the production of glutamate-derived chelating agents. These agents, especially tetrasodium glutamate diacetate (GLDA), provide metal ion seizure and water-softening functions in sustainable cleaning and industrial water treatment. The raw material integrates at early neutralization and chelation stages, requiring purity assurance for downstream environmental safety and regulatory benchmarks in non-food applications.

    Industry compliance standards

    • OECD guidelines for biodegradability (Test No. 301)
    • Detergent Ingredient Registration (EU Detergent Regulation EC/648/2004)
    • US EPA Safer Choice Program for ingredients
    • EN ISO 14001 for environmental management in chemical plants

    Typical usage ratio

    • Input range: 0.5–2.0 mol DL-Glutamic Acid per mol chelating agent produced, depending on desired final salt and formulation strength. Batch excess required for waste minimization and process completeness.

    Downstream process integration

    • Neutralization with caustic and acetic acid under temperature-controlled agitation.
    • Chelation product isolation by spray-drying or crystallization before blending with base detergent compound.
    • QC checks for residual free amino acid to ensure compliance with environmental toxicity limits.

    Final product types

    • Household and industrial laundry detergent powders
    • Dishwashing detergents and tablet formulations
    • Industrial process water softening agents
    • Biodegradable surface cleaner concentrates
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    Certification & Compliance
    More Introduction

    DL-Glutamic Acid: Our Experience as a Chemical Manufacturer

    Ever since we began making amino acids in bulk, DL-Glutamic Acid has stood out in our production lines for its unique role and performance. This product, with its clear granularity and stable flow, seems like a small part of a broader catalog—until you see the list of requests from food processors, pharmaceutical companies, biotechnology labs, and industrial additives suppliers pouring into our sales office every quarter. DL-Glutamic Acid (sometimes referenced by customers as racemic glutamic acid or Glu), is much more than a standard commodity. Every batch we produce serves a need that goes beyond pure chemistry.

    Our Approach to Manufacturing DL-Glutamic Acid

    We have always believed that quality comes from consistency in the manufacturing process. At our site, DL-Glutamic Acid is synthesized by a well-honed fermentation followed by controlled racemization steps. This gives a finished product that blends equal parts D- and L- enantiomers. From raw feedstock selection to finished material inspection, we keep our documentation detailed and our controls rigorous. The product is offered most frequently as a white crystalline powder, highly soluble and showing a purity well above 99%. Moisture content tends to stay below 0.5%, with heavy metal contaminants routinely tested down to trace levels using ICP-MS and other trusted techniques. In nearly two decades, our average yield and batch reliability supports hundreds of downstream manufacturers demanding the same tight tolerance order after order.

    Product Model and Specifications

    Commercial clients often approach us with a particular use in mind. Some want a standard mesh size between 20 and 80, while others ask for finer or coarser granules to speed up or slow down reaction rates in their downstream applications. DL-Glutamic Acid, in our case, usually takes the form of anhydrous powder, but we also offer it as a monohydrate upon request. Assay values consistently exceed 99% by HPLC, which is appreciated by food processors and laboratory customers who require analytical consistency in every lot received. For those working with highly sensitive applications, our team conducts full microbiological testing to guarantee freedom from pathogens. All packaging gets nitrogen-flushed to prevent oxidative changes before reaching you.

    How Customers Use DL-Glutamic Acid

    From our perspective as manufacturers, one fascinating part of this business comes from conversations with buyers who understand that the “DL” form carries attributes not present in the pure “L” version. Animal nutritionists have explained at length that the racemic mix offers a broader metabolic profile across diverse livestock populations, especially in feed supplement production. Specialists for biodegradable plastics and resins request the product in large drum quantities because it functions as a viable chiral precursor in polymerization. Meanwhile, biochemists focus on standardized batches for culture media, precisely adjusting amino acid content to optimize cell growth in research fermenters and production bioreactors. Pharmaceutical groups investigating custom peptide synthesis frequently order kilogram to ton-level volumes, favoring the DL-form for developing reference substances, intermediates, and, on rare occasions, for full-scale active pharmaceutical ingredients.

    Requests for different particle sizes or specific solubility rates often originate from flavor and additive formulators who use DL-Glutamic Acid to tune umami and savory notes in foods, sauces, or seasoning blends. The distinct taste-modifying properties of DL-form differ noticeably from monosodium glutamate (MSG) or pure L-glutamic acid, which sharpens our focus on precise physical characteristics. On rare occasions, we work with teams who want to create bulk fermentation broths for environmental remediation and soil amendment applications. In those cases, the stability of DL-Glutamic Acid becomes a deciding factor.

    DL-Glutamic Acid versus Other Amino Acids

    Our technical crew has accumulated stacks of data comparing DL-Glutamic Acid to similar amino acids, such as L-Glutamic Acid or D-Glutamic Acid. You can’t lump their applications together, even if they share a molecular backbone. For instance, the pure L-enantiomer dominates pharmaceutical and clinical nutrition because specific enzymes and metabolic processes only recognize the L-form. In contrast, DL-Glutamic Acid carries significant value where both enantiomers might exert functional effects or where stereospecificity plays a smaller role in overall performance. Batch costs also decrease because synthesis and downstream separation demand less labor and equipment for racemic products. Bulk animal feed manufacturers and technical grade applications frequently request the DL-type, which streamlines both handling and sourcing for them. Later, when the specification changes or a regulatory shift happens, our team can ramp up or divert stocks between the DL and L-forms more flexibly than if we manufactured one or the other exclusively.

    On the flavor side, DL-Glutamic Acid doesn’t behave identically in culinary or industrial processes when compared to monosodium glutamate or to pure L-glutamic acid. Professional chefs and development scientists in the food industry have reported to our technical support team that DL-Glutamic Acid imparts a mellow, longer-lasting taste profile in soups and broths, without the sharpness sometimes encountered in MSG or L-form blends. That difference shapes niche uses in food innovation and defines where product lines diverge.

    Quality Control: Lessons Learned from Decades of Production

    Consistency means more than passing a certificate of analysis. Fluctuations in batch consistency sink many projects and burn up time for technical teams. Our tight process parameters—maintained by automation and hands-on checks—reduce deviations and warranty claims. In situations where a client’s instrument picks up slight off-spec values, our staff investigates at the root batch and fixes process issues before the next campaign goes live. Years ago, minor fluctuations in pH and odor profiles emerged in shipments for a leading food ingredient company. The experience pushed us to refine our material handling, introduce closed-loop cleaning and air filtration, and switch out several legacy lines for modern, stainless steel production suites.

    As a result, today’s DL-Glutamic Acid passes every microbial, elemental, and performance test thrown at it. It’s not just about purity, but also about color, solubility, ash content, and absence of foreign matter. We refuse to cut corners, and if something falls short of our standards, the product won’t leave our facility. Many long-standing supply contracts rely on this uncompromising mindset, and we intend to keep earning trust through vigilance.

    Packaging and Logistics: Responding to Customer Feedback

    We pack DL-Glutamic Acid in multiple container sizes, from multi-layer fiber drums lined with food-grade plastic to high-barrier polyethylene bags. Some customers running extensive, automated dosing lines demand easier opening, flow control, and reduced dust. In direct response, we designed moisture-proof liners that open cleanly and do not leave fibrous residues. In the early days, we often faced breakages and contamination risk during export shipments, especially by sea. Over the years, intensive feedback led us to switch out old packaging materials for those with better shock resistance and oxygen barriers. Our dispatch team works with clients’ logistics partners for every destination, making sure labeling, certificates, and customs documents match destination requirements.

    Temperature changes in shipping containers often cause caking or mild hydration in hygroscopic materials. We learned to mitigate that risk by buffering the packaging and shipping only in low-humidity conditions wherever possible. Feedback loops with our transporters and logistics managers on both ends keep us informed, leading to incremental improvements in every shipping cycle. Bulk users who need 10 tons, or boutique startups wanting just a few boxes, get approached with the same commitment to quality and delivery reliability.

    Safety, Traceability, and Transparency

    DL-Glutamic Acid poses a very low risk profile compared to some of the hazardous chemicals common in our plant. Still, we maintain strict OSHA-style protocols and supply full traceability for every lot produced. The batch number, synthesis records, and analytical files are tied to each pack that leaves our warehouse. If a quality concern or regulatory question arises years later, we can pull hard data for every step, from raw material receipt to final QC clearance. Customers running international operations—where ingredient traceability or allergen reporting poses unique challenges—lean heavily on this level of transparency. Each audit or customer site visit reaffirms the trust built into our system. Site safety officers run regular refreshers on GMP, food grade practices, and emergency response. We teach new hires to treat every container as if it is headed to their own families. That’s the level of care our stakeholders expect and receive.

    Regulatory Considerations and the DL Configuration

    The regulatory landscape for amino acids continues to change, especially with growing scrutiny over synthetic and racemic products. Different countries assign unique codes or restrictions to DL-Glutamic Acid, often distinguishing it from its L-form counterpart. Food, feed, and pharma registrations require a detailed product dossier, covering both molecular origin and enantiomeric ratio, in-country testing, and conformity to internationally accepted purity and contaminant limits. Our regulatory team tracks new developments, that way labels, documentation, and sales strategies reflect the reality of import and export requirements. Being a manufacturer rather than a middleman allows us to communicate directly and transparently about composition, process details, and relevant certificates.

    Regulators in some regions specify application limits, especially in products where the L-form is known to be biologically active. Our standard procedure keeps product planning nimble enough to adapt quickly if a new rule emerges in one country or region. We prepared for years to maintain dual certification of both DL and L forms, and collaborate with external labs for independent verification when new standards become law.

    Comparing the Manufacturing of DL-Glutamic Acid with L-Glutamic Acid

    Synthesizing the DL form presents notable differences from producing only the L form. For food grade L-glutamic acid, fermentation with specific bacterial strains gives almost pure L-enantiomer output, which can go straight to downstream processes after moderate purification. DL-Glutamic Acid needs either chemical racemization or a distinct fermentation pathway, which in our experience adds both cost and process complexity at scale. Deciding which route to follow depends on customer need, energy usage, and intended application. Over the years, we learned that the choice hinges on adequate market research and honest dialogue with procurement specialists. For both forms, we prioritize sustainable sourcing for core feedstocks using regional supply chains to minimize freight and carbon intensity.

    Waste management also changes along with the product. DL-Glutamic Acid synthesis can yield higher levels of racemization by-products and sometimes higher salt loads in effluent streams. Addressing this, we built an on-site treatment plant to recycle and neutralize these by-products, making sure we remain within compliance and reduce impact on our local community. That remains a piece many resellers and traders do not fully appreciate, as their involvement ends long before waste ever leaves the factory.

    Customer Education and Application Guidance

    We actively support customers in understanding where DL-Glutamic Acid aligns or diverges from other glutamic acid forms. Many end-users—especially those moving from small scale to production runs—benefit from a frank discussion of pros and cons. We organize regular technical workshops and invite current and prospective clients to visit our production suites, view the analytical labs, and speak with our senior process chemists about upstream sourcing choices and downstream impacts. Application guidance covers everything from solubility optimization to best practices for blending with other amino acids, minerals, and flavoring agents.

    A common misconception among newcomers is to treat all glutamic acid products as substitutes for each other. With DL-Glutamic Acid, the balance of D and L forms often shifts the functional properties in end use, influencing everything from animal growth rates to product shelf life. By clarifying these points during onboarding or technical Q&A, we help customers avoid costly trial-and-error runs and keep projects on schedule.

    Continuous Improvement and Industry Collaboration

    Making DL-Glutamic Acid at a commercial scale is less about textbook chemistry and more about adapting manufacturing engineering to evolving standards and demands. We participate in industry consortia that set voluntary safety, quality, and sustainability guidelines. These collaborations feed knowledge back into our process planning and material selection. We benchmark our analytical procedures and product attributes against global leaders, striving to stay one step ahead of minimum regulatory requirements. Staff participate in professional training, and our technical team stays in regular contact with university research groups working at the frontier of amino acid synthesis, fermentation, and application science.

    Clients from food, pharma, and specialty chemical industries often raise queries or highlight emerging requirements. This feedback helps us modify our production approaches and analytical screening protocols. For example, recent trends in non-GMO certification have led us to expand our verification programs, enabling clients to market finished goods that meet end-customer expectations. Our involvement in these industry-wide dialogues makes sure we remain responsive, relevant, and competitive.

    Looking Ahead: Sustainable Manufacturing and New Applications

    As stewards of a legacy chemical product, we recognize the pressure to innovate and deliver environmental value. Our investment in process efficiency delivers lower energy use and less waste than legacy approaches. We have begun transitioning to renewable power sources for several of our main process lines, and optimized water treatment to minimize discharge. After years of hearing from clients focused on reducing embodied carbon in their upstream supplies, we now include life-cycle data and greenhouse gas reports with every major corporate bid. It’s no longer enough to offer a basic certificate of analysis when leading brands—both food and pharma—ask for end-to-end accountability.

    In the research pipeline, our team examines new uses for DL-Glutamic Acid, including its growing potential in green solvent synthesis, biodegradable adhesives, and performance polymers. We collaborate with customers eager to commercialize these innovations, offering test batch quantities and technical support as they pilot newer products. The versatility of DL-Glutamic Acid guarantees that even traditional markets like animal nutrition and food ingredients continue to evolve, spurred on by consumer, regulatory, and technological shifts.

    Summary: The Manufacturer’s Commitment to Value

    For those searching for DL-Glutamic Acid that stands up to scrutiny, experience from decades of manufacturing forms the backbone of reliable supply. We know clients stake their own brand and reputation on the materials they use. By taking control at every stage—sourcing, production, quality testing, packaging, regulatory compliance, logistics, and technical support—we deliver certainty and performance. Our customers have depended on us through shifting markets, regulatory changes, and supply chain upheavals. The result: products built for reliability, engineered for quality, and supplied with the confidence only a true manufacturer can offer.