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DL-Catechin

    • Product Name DL-Catechin
    • Alias (+)-Catechin
    • Einecs 204-299-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    602400

    Product Name DL-Catechin
    Chemical Formula C15H14O6
    Molecular Weight 290.27 g/mol
    Appearance Off-white to beige powder
    Solubility Soluble in ethanol, methanol, slightly soluble in water
    Melting Point 177-180°C
    Cas Number 154-23-4
    Purity Typically ≥98%
    Storage Conditions Store in a cool, dry place; keep away from light
    Uses Antioxidant, food additive, research reagent
    Synonyms DL-Cyanidanol, (+/-)-Catechin
    Ph Neutral (in solution)
    Stability Stable under recommended storage conditions

    As an accredited DL-Catechin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing DL-Catechin is packaged in a sealed, amber glass bottle containing 25 grams, with clear labeling for safety and compound identification.
    Shipping DL-Catechin is shipped in tightly sealed containers, protected from light, moisture, and heat. It is classified as a non-hazardous material, permitting standard delivery via air, sea, or ground. Proper labeling and documentation are provided, ensuring safe transit and compliance with relevant transportation regulations.
    Storage DL-Catechin should be stored in a tightly sealed container, protected from light and moisture, in a cool, dry place. Ideally, storage temperatures should be below 25°C. The chemical should be kept away from strong oxidizing agents and incompatible substances. Proper labeling and handling procedures should be followed to ensure stability and safety during storage.
    Application of DL-Catechin

    Applications of DL-Catechin in Industrial Manufacturing

    DL-Catechin is a synthetic catechol derivative widely implemented as an active ingredient across several precision-driven industries where antioxidant, stabilizing, and complexation effects are utilized in strict compliance with sector-specific standards. Below, we outline targeted downstream segments where DL-Catechin serves highly defined functions in regulated production environments.

    1. Food Additives for Beverage Clarification

    In beverage manufacturing, particularly in tea-based drinks and specialty juice lines, DL-Catechin is applied as a clarifying and browning-inhibitor agent. It contributes to product shelf-life extension and color stabilization, addressing polyphenol oxidation issues typical in high-catechin or anthocyanin systems. Process control demands precise dosing to maintain both functional and regulatory thresholds, with attention to potential flavor interactions during blending, thermal treatment, and aseptic bottling.

    Industry compliance standards

    • GB 2760-2021 (China Food Safety National Standards for Food Additives)
    • FAO/WHO Codex Alimentarius General Standard for Food Additives (CODEX STAN 192-1995)
    • EFSA Scientific Opinion on Flavan-3-ols as Food Additives (EU Regulation No 1333/2008)
    • HACCP program and FSSC 22000 food safety system

    Typical usage ratio

    • 0.01–0.1% w/w of total formulation, adjusted according to tannin or polyphenol content and beverage pH; usually verified by total phenolics titration during pilot blending.

    Downstream process integration

    • Added post-extraction but pre-filtration, typically in blending tanks prior to pasteurization and filling, with adjustment after colorimetric QC check, especially for tea-based and natural fruit beverages.

    Final product types

    • Bottled iced teas
    • Functional fruit beverages
    • Ready-to-drink herbal infusions
    • Premium juice blends targeting polyphenol content claims

    2. Cosmetic Emulsion Antioxidant Stabilizer

    Leading cosmetic manufacturers add DL-Catechin during the aqueous phase of emulsion systems as a non-natural, potent antioxidation agent. The compound retards oxidative spoilage of sensitive vitamins and plant actives under light and heat exposure, directly supporting shelf-life claims. Formulators employ differential scanning calorimetry and accelerated stability tests to define maximum additive ratios that avoid formulation instability or skin sensitivity, complying with detailed cosmetic raw material catalogs and safety dossiers.

    Industry compliance standards

    • EU Cosmetic Regulation (EC) No 1223/2009
    • China Cosmetic Supervision and Administration Regulation (CSAR), Ingredient Index 2023 Edition
    • US FDA Voluntary Cosmetic Registration Program (VCRP) and INCI listing
    • ISO 22716:2007 Cosmetics — GMP Guidelines

    Typical usage ratio

    • 0.01–0.05% w/w, variable based on exposure to heat/light and compatibility with vitamin C, tocopherols, and botanical extracts; higher concentrations assessed under patch testing for hypoallergenic lines.

    Downstream process integration

    • Introduced into the aqueous phase at 40–45°C with continuous stirring prior to emulsification, often co-dissolved with chelating agents; monitored during batch QC for oxidation-reduction potential.

    Final product types

    • Emulsion moisturizers (face and body creams)
    • Liquid foundation bases
    • Serum and essence pre-mixes with antioxidant claims
    • Sun care formulations where stability of UV filters requires antioxidant protection

    3. Pharmaceutical Intermediate for Nutritional Supplement Production

    DL-Catechin functions as a reference flavonoid in the pharmaceutical sector, particularly in the synthesis of standardized nutraceutical tablets and capsules. Careful documentation is mandatory for qualifying material source and purity, as its presence in finished supplements targets antioxidant activity labeling. Regulatory inspection emphasizes traceability through batch records, validated HPLC assays, and GMP-compliant blending protocols, with applicational distinctions from botanically sourced catechins.

    Industry compliance standards

    • USP Dietary Supplement Chapter <823> (Catechin reference and assay)
    • China Pharmacopoeia 2020 (Volume IV — Health Food Raw Materials)
    • GMP for Dietary Supplements (21 CFR Part 111, USA)
    • ISO 22000:2018 Food Safety Management for ingredients traceability

    Typical usage ratio

    • 10–50 mg per tablet or capsule (0.5–2% w/w), set to match total flavonoid label claims and bioaccessibility targets in finished dose forms; adjusted after risk assessment for interactions with vitamins or other polyphenols.

    Downstream process integration

    • Direct-dosed in V-blender as a dry powder, with real-time monitoring for homogeneity and moisture pickup before compression or encapsulation; checked for degradation during thermal stability testing.

    Final product types

    • Antioxidant dietary tablets
    • Catechin capsules
    • Nutritional supplement powder sachets
    • Multivitamin/mineral blends targeting oxidative stress support

    4. Analytical Reagent in Laboratory and QC Environments

    Chemical and pharmaceutical QC labs use DL-Catechin as a standard for instrument calibration in the quantitative analysis of tea extracts, flavonoids, and antioxidant preparations. This application demands certified reference material status, precise documentation of purity and spectral identity, and integration into validated procedural frameworks for HPLC and UV/VIS spectroscopy. Certified weights and homogeneity of the reference batch underpin data reliability in commercial and in-house quality control workflows.

    Industry compliance standards

    • ISO 17034:2016 (General Requirements for Reference Material Producers)
    • ISO/IEC 17025:2017 (Testing and Calibration Laboratories)
    • USP <561> Articles of Botanical Origin Method Validation
    • FDA cGMP for Laboratories (21 CFR 211.160)

    Typical usage ratio

    • 0.5–5 μg/mL in standard solution, prepared gravimetrically with precise balance calibration; working concentrations depend on method linearity and sample matrix requirements in quantitative assay.

    Downstream process integration

    • Prepared in solvent (ethanol or methanol) and filtered before use as a primary standard in HPLC, capillary electrophoresis or UV calibration curves for quantitative catechin content in complex product matrices.

    Final product types

    • Calibrated analytical standards
    • Tea polyphenol content reference materials
    • Certified QC control solutions for antioxidant content assays
    • Proficiency testing samples distributed to independent laboratories

    5. Polymer Stabilizer in Specialized Film and Coating Formulations

    Within polymer engineering, primarily for food packaging films and specialty coatings, DL-Catechin performs as an oxidative degradation inhibitor. Its inclusion reduces free radical-induced chain scission during extrusion and extends UV-stability in transparent or pigmented films. Allergies, migration, and extractable levels in finished packaging undergo strict migration testing, with process compatibility studies during melt-processing to confirm mechanical property retention and color stability.

    Industry compliance standards

    • EU Regulation (EU) No 10/2011 on Plastic Materials Intended for Food Contact
    • FDA 21 CFR 177.1520 (Olefins Polymers) and 21 CFR 178.3297 (Antioxidants and Stabilizers for Polymers)
    • China GB 9685-2016 Additive Usage in Food-contact Materials
    • ISO 9001:2015 for production traceability and batch documentation

    Typical usage ratio

    • 0.02–0.1% w/w in masterbatch or direct polymer blend, with adjustment based on target OIT (oxidative induction time) and UV resistance measured during formulation trials.

    Downstream process integration

    • Added to polymer pellets or resin before compounding, with thermal stabilization profiles confirmed during extrusion or casting, and checked for compatibility with pigments and slip agents.

    Final product types

    • Food packaging films (mono- and multi-layer)
    • Clear wrap and tray linings where oxidation resistance is specified
    • UV-protective over-lacquers for specialty flexible packaging
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    Certification & Compliance
    More Introduction

    DL-Catechin: Direct from the Source

    Shaping Purity and Consistency in DL-Catechin Manufacturing

    When running our production lines, there’s always a sharp focus on meeting high standards for DL-Catechin. We maintain tight control of synthesis routes and batch reactions using precision equipment in a closed environment. Consistency in composition gives end users confidence in repeatable results. We use high-purity starting materials and specialized separation techniques, including crystallization and column chromatography, so every lot meets defined purity benchmarks. Analytical validation is woven through every stage—HPLC, melting point checks, and moisture tests guide our operators as much as our own experience does.

    Model, Specifications, and Quality Markers

    Customers who ask about DL-Catechin are typically looking for reliable purity, particle size, and controlled moisture. Our standard model runs with assay levels over 98%. The color is pale yellow to near white, and the texture is a fine powder suitable for most functional and application-driven mixing. Typical moisture levels rank below 1.5%. Ash content and heavy metals are checked batch-by-batch. We’ve learned that shrinkage in particle size variation—even by five or ten microns—can impact solubility and blending. For this reason our milling and screening stages are tuned for stable mesh numbers. Each order is packed in double polyethylene liners inside fiber drums or custom packaging, reducing the risk of cross-contamination and unwanted moisture pickup.

    Understanding the Science Behind DL-Catechin

    DL-Catechin belongs to the flavan-3-ol group. Its molecular structure gives it a distinct profile compared to natural catechins often found in plant extracts. By delivering it in the synthetic DL form, we achieve a precise combination of both stereoisomers, not just the naturally prevalent (-)-catechin or (+)-catechin isolated from tea or cocoa. Our chemists monitor enantiomeric ratios and use polarimetric testing as an extra check.

    The benefit of synthetic DL production lies in its predictability. Each batch brings the same proportions and appearance, with no surprises from varying seasonal biomass or geographic harvests. For research, analytical work, or formulation design, the lab can count on what comes out of our reactors today to match what was available last year. That consistency matters when product development takes months or years—recipe drift caused by upstream fluctuations is one of the most common sources of wasted time in application labs.

    Applications: Putting DL-Catechin to Work

    Most requests for DL-Catechin focus on its use as a standard for analytical assays, a calibration material for HPLC, or a starting point in synthetic routes for more complex molecules. Within chemical research, universities, and commercial R&D departments, labs often require this reference material for method validation or impurity profiling. Our batches target exacting purity specifications and impurity controls because minor deviations change the results of comparison studies and analytical standards.

    Wider uses show up in the food and beverage sector, cosmetics, nutraceuticals, coatings, and specialty chemicals. In dietary supplement exploration, formulators may compare the action of synthetic catechin to that of purified natural forms, running controlled tests to observe bioactivity. Regulatory bodies and academic journals expect clear evidence that the compound’s purity supports the stated results—our documentation supports those claims with structure and compositional certificates. In cosmetics, especially for antioxidant systems, the DL synthetic version serves as a stable, well-documented alternative to plant-derived batches that can shift with every crop and climate shift.

    Industrial queries sometimes tap DL-Catechin as an intermediate. Plants focused on advanced organic transformations or chiral catalysis occasionally request a predictable, non-plant supply to keep pilot lines running, or to avoid the risk of pesticide carryover found in some extract-based sources. The synthetic model sidesteps terroir and agricultural constraints—this offers control and transparency to every downstream user, whether in a small pilot run or a full-scale batch.

    Differences Compared to Other Catechin Sources

    DL-Catechin often gets compared to natural catechin extracted from green tea, cocoa, or similar botanicals. The molecular backbone is the same, but there is an important distinction at the stereochemical level. Natural catechin from tea typically yields the (+)-catechin or (-)-epicatechin isomers. Our synthetic process delivers an equal-ratio mixture of the D- and L- enantiomers, increasing consistency. This is what makes it attractive for analytical or quality control applications where reference standards cannot rely on agricultural variability.

    Sourcing from plants means riding out fluctuations in active compound concentrations—one harvest may yield different isomeric ratios than the next, and agrochemicals or residual solvents raise concerns in sensitive formulations or studies. Our technicians monitor each production step using robust controls, enabling customers to trace the batch lineage and eliminating guesswork about what’s inside the drum. The paperwork behind the scenes builds trust: pH, residual solvent, and heavy metal test results are provided up front, reflecting confidence in our own processes.

    With high-volume beverage or food processors, natural extracts may get a premium for “natural” labeling, yet for scientific, industrial, and cosmetic sectors, the value lies in batch-to-batch dependability—knowing the chemical identity in every scoop or gram is non-negotiable. Academic researchers often look for DL-Catechin as a control sample. They match it against a botanical sample to assess how mixture of isomers changes observed biological activity. Practicality in manufacturing counts for just as much as taxonomic origin or marketing claims.

    Challenges and Solutions in DL-Catechin Production

    Scaling up DL-Catechin production takes more than basic chemistry—it demands patience and refined equipment. The balance between yield maximization and impurity minimization never sits still. Reactors have to operate at stable temperatures for hours on end. Operators must respond quickly if ambient humidity rises or a mill produces excess fines. Our stability studies focus on storage and pack-out conditions; nothing erodes confidence faster than product clumping or breakdown before it reaches a customer’s bench.

    Environmental challenges guide material procurement and waste management on-site. Our solvent selection leans green where possible to reduce downstream treatment costs and impact. Filtration and washing protocols are regularly reviewed for safety and efficiency. Years in the lab have taught us that cutting shortcuts with quenching or purification only creates chaos later—with so many eyes on reference standards, transparency about our cleanup methods builds trust with health and safety officers as well as quality assurance staff beyond our own gates.

    Staff retention matters. Training experienced chemists and plant operators cuts the risk of batch contamination or loss. We set quality bonuses tied to process vigilance and error reporting. Data shows that lines led by technicians with five years or more experience generate less waste and reduce complaints. Internal audits encourage openness rather than punishment—mistakes become lessons for tomorrow’s shift. Peer review and continuous training help us avoid the sort of siloed thinking that breaks long-term workflows.

    Stringent Quality Control Supports Confidence

    End users expect transparency. We provide full documentation, including chromatograms, mass spectrometry printouts, and impurity assessments. A robust internal tracking system links each batch to operator logs, synthesis records, and storage conditions. This paper trail stands ready for regulatory or customer review. Over the years, auditors and client-side QA teams have highlighted our openness when rating supplier reliability. The message is always clear: strong paper trails and routine in-process testing reduce concerns about out-of-spec product or accidental mixing of materials.

    Customer feedback drives process improvements in measurable ways. If an academic lab receives a shipment and flags a color shift or caking, our QC team investigates—not just the batch itself, but nearby batches and process steps as well. Data sharing with academic or industrial partners helps test hold and transport stability under diverse shipment conditions. We adjust silica content or introduce augmented liners in response to real use-cases, not just hypothetical ones. This feedback cycle keeps our DL-Catechin finding its way into demanding new applications year after year.

    Regulatory Insights and Compliance

    The global market for catechins attracts scrutiny from national health authorities, certification bodies, and regulatory groups. We stay ahead of evolving requirements by cataloging updates from food, pharma, and environmental regulators. Synthetic catechin batches run through allergen screening and residual solvent analysis on top of heavy metal and pesticide clearance. The documentation enables end users—from academic labs to commercial developers—to clear their own approval hurdles with minimum disruption.

    As new food regulations and RoHS standards emerge, our compound certifications are updated proactively. Product recalls, even rare ones, shape how we gather and present compliance data in advance, rather than scrambling after a question lands on a regulator’s desk. We share storage best practices and shelf-life projections based on actual stability data and not just predictions. This approach lessens the risk of compliance-related communication breakdowns, which can lead to production delays elsewhere in the supply chain.

    Supporting Research and New Technologies

    DL-Catechin finds a unique niche in research environments. Scientists studying antioxidant networks or synthetic modification routes request well-characterized, reliable catechin to avoid unpredictable outcomes. With fermenter and reactor access, we sometimes support contract research—either collaborating to improve existing catechin analogs or as part of green chemistry initiatives. Our willingness to refine process steps is directly shaped by what comes back from the field: feedback on solubility, compatibility in specific solvents, or side reaction risk leads our chemists to tweak protocols for future runs.

    We invest in analytical method development, working alongside universities and independent researchers. Comparative studies using HPLC and NMR serve to verify identity and highlight meaningful differences with botanical extracts. Open exchange of data—on crystallization, solubility, or thermal stability—supports researchers chasing answers to new questions. This type of industry-research collaboration spurs incremental improvements to the point where both bench scientists and producers benefit.

    Packaging, Storage, and Shelf-Life Lessons Learned

    Environmental controls in storage serve as insurance for purity. Based on the feedback loop between QC lab and warehouse, we adopted double-walled drums lined with moisture barriers. Temperature and humidity checks run every shift, not just at shipping. Dealing with catechin means keeping oxygen exposure low; too much air leads to color changes and degradation. Every year, old packaging and labeling protocols are revisited—recent improvements cut down incidence of clumping after international air transport or during unplanned storage in high-humidity regions.

    Experience counts in labeling as well. Small misprints or incorrect batch numbering can lead to confusion downstream—a lesson learned after an incorrectly coded shipment led to a full-scale investigation by the customer’s QA team. Regular re-training in documentation, both on paper and digital, helps keep mistakes minimal. Real-time tracking combined with digital batch records slashes time spent fielding status requests. Clients sometimes run their own stability trials and share those results. These exchanges are rarely formal, but the aggregated knowledge helps drive all of us toward more durable packaging choices and shipping methods.

    Industry Partnerships and Building Trust

    DL-Catechin’s value often emerges through steady collaboration with end users. Whether it’s supporting a pilot project or troubleshooting a formulation mismatch, transparency and a willingness to share lab reports build the kind of reputation that cannot be bought. When customers talk directly to production chemists instead of anonymous sales staff, there is less room for misunderstanding. We occasionally invite feedback on process tweaks, sharing the thinking behind a new purification method or pack-out tweak.

    Our core users include research institutes, contract manufacturers, analytical laboratories, and cosmetics brands testing next-generation antioxidants. Each sector expects open lines of communication, from technical queries to complaint resolution. That mutual trust is reinforced by a real-world track record—on-time deliveries, upfront certificate sharing, and continuous quality monitoring. We know from years of experience that relationships built on assessments and audits forge the most resilience; problems addressed early and openly create learning opportunities for both supplier and customer.

    Looking Forward: Evolving Standards in Catechin Production

    The market for DL-Catechin continues to expand as new research invites closer scrutiny of isomer-specific effects and bioactive potential. Advances in synthesis routes bring efficiency gains, but nothing beats disciplined sampling and real-time process review for keeping quality where it belongs. Breakthroughs in eco-friendly solvents and smart reactors, driven by partnerships with tech developers, promise greener production with less waste. Our ongoing drive to improve is shaped as much by production constraints as by lessons learned from decades of hands-on manufacturing.

    Warnings about supply chain fragility or commodity chemical substitution prompt us to keep rigorous internal audits and third-party verification programs in place. Real transparency about process, coupled with willingness to adapt when new reliability or safety issues surface, keeps both our team and our customers prepared for the future.

    Making DL-Catechin is not just a business—it’s a partnership with researchers, formulators, and industry pioneers across the globe. The compound itself may look like a simple powder, but its journey from factory floor to research bench is made robust by the experience, investment, and hard-earned knowledge that drives each batch. Our daily focus stays on stability and reliability, with an eye on improvement. The big picture runs through every drum that leaves our gates: proven chemistry, humane production practice, and an open door for collaborative progress.