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HS Code |
489616 |
| Product Name | DL-Asparagine Monohydrate |
| Chemical Formula | C4H8N2O3·H2O |
| Molecular Weight | 150.14 g/mol |
| Appearance | White crystalline powder |
| Solubility In Water | Freely soluble |
| Melting Point | 234-236°C (dec.) |
| Cas Number | 5794-13-8 |
| Purity | Typically ≥98% |
| Ph Value | 5.0-6.5 (10 g/L, H2O, 20°C) |
| Storage Conditions | Store at 2-8°C, dry place |
| Synonyms | DL-2-Aminosuccinamide monohydrate |
| Odor | Odorless |
| Ec Number | 611-388-2 |
| Usage | Biochemical research, cell culture media |
As an accredited DL-Asparagine Monohydrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White, sealed HDPE bottle with a blue screw cap, labeled "DL-Asparagine Monohydrate," net weight 100 grams, hazard and storage information displayed. |
| Shipping | DL-Asparagine Monohydrate is shipped in a tightly sealed container, protected from moisture and direct sunlight. It should be kept in a cool, dry, and well-ventilated area during transit. Standard ground transportation is typically used, with labeling compliant with chemical safety regulations. Avoid exposure to incompatible substances and extreme temperatures. |
| Storage | DL-Asparagine Monohydrate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area. Protect it from moisture and direct sunlight. Store at room temperature or as specified on the manufacturer’s label, typically between 2-8°C. Avoid sources of ignition and incompatible substances. Ensure proper labeling and access only to trained personnel. |
Applications of DL-Asparagine Monohydrate in Industrial ManufacturingDL-Asparagine Monohydrate serves specialized functions across multiple industrial manufacturing sectors. As a manufacturer, we supply this raw material to customers in various high-compliance fields who integrate it based on unique technical and regulatory requirements. The following sections detail four primary, industry-validated downstream use cases of DL-Asparagine Monohydrate, with practical guidance on compliance, formulation ratios, process chemistry, and final product outputs. 1. Pharmaceutical API SynthesisMajor pharmaceutical producers employ DL-Asparagine Monohydrate in the synthesis of peptide-based active pharmaceutical ingredients. It acts as a non-essential amino acid building block during solid-phase peptide assembly, providing control over chirality and side-chain compatibility in multi-step sequences. Manufacturers ensure material traceability from receipt to final formulation and maintain tight impurity profiles to comply with international regulatory submissions. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Food Ingredient Production (Protein Hydrolysates & Nutraceuticals)Food processing manufacturers integrate DL-Asparagine Monohydrate as a component in enzymatic hydrolysis of protein extracts for nutritional blends. Its role as a free amino acid supports reconstitution of amino acid spectra in protein hydrolysates used for supplements, functional foods, and infant formulas. Process controls regulate thermal degradation and potential acrylamide formation during downstream drying or heating steps. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Cell Culture and Bioprocessing Media ManufacturingProducers of cell culture and fermentation systems utilize DL-Asparagine Monohydrate to support cell line viability and productivity during upstream bioreactor operation. The compound enters media formulations to supply a readily available nitrogen source and to balance amino acid content critical for recombinant protein and antibody expression. Specifications require low endotoxin and bioburden levels to align with biologics production risk management. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Diagnostic Reagent and Enzyme ProductionManufacturers of analytical diagnostic kits incorporate DL-Asparagine Monohydrate as a key reagent in enzymatic assays where accurate quantification of asparaginase or related metabolic activity is required. It functions as a standard substrate in clinical chemistry analyzers and in quality control of enzyme preparations used in food and pharmaceutical sectors. Detailed BSE/TSE risk assessments and source documentation are required for compliance in regulated environments. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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Working every day at the intersection of chemistry and function, we see how every small improvement in production reflects in our final products. DL-Asparagine Monohydrate stands out in our amino acid line thanks to its carefully controlled synthesis and measuring protocols. As a manufacturer, we don’t see this compound as just another listing in a product catalog—it’s a core ingredient that finds its way into research, food analysis, biochemical studies, and specialized manufacturing projects.
Our model for DL-Asparagine Monohydrate carries a clear fingerprint: consistent physical quality, tightly managed purity, and a reliable hydration profile. This approach means every kilogram leaving our factory passes detailed internal checks for color, flow, crystalline structure, and solubility. We avoid shortcuts, such as minimal filtration or blurry sourcing, because we know laboratories and industrial processors rely on characteristics that don’t waver between batches.
This compound serves two sectors especially well: biochemical research and processed foods. From our own work in upstream applications, we’ve watched scientists zero in on asparagine’s participation in protein synthesis and amino acid metabolism. Many researchers prefer the DL-form because it contains both D- and L-isomers, granting flexibility across a broader range of enzyme and receptor studies than the pure-L or pure-D forms. Each monohydrate molecule carries a single water unit, which makes it behave differently from the anhydrous version during solution prep and weight calibration. This has measurable effects, especially when preparing calibration standards or pharmaceutical intermediates.
In food analysis labs, our DL-Asparagine Monohydrate serves as a spike or marker during asparagine quantitation or acrylamide risk assessments. Asparagine content often steers formulation choices, since the Maillard reaction in heated foods links directly to acrylamide production. Our experience has shown that when labs or manufacturers skip minor quality checks, their acrylamide predictions drift, leading to regulatory headaches, especially in export-oriented food chains.
After years producing both monohydrate and anhydrous asparagine, we see clear reasons for choosing the hydrated form in select workflows. Water content changes solubility kinetics, storage stability, and even the mixing behavior with other amino acids. Our chemists often debate the advantages for chromatography, cell culture prep, or fermentation experiments. The monohydrate doesn’t clump or cake as easily in humid climates—a practical point for handling and storage. It also delivers known mass-to-mole calculations without ambiguity, which is especially valued in quantitative analysis.
Technical staff repeatedly report that weighing and dissolving DL-Asparagine Monohydrate eliminates one extra correction when constructing calibration curves. For teaching laboratories—where time and transparency matter—small differences like this can sharpen results without additional training or guesswork. Years of feedback from academic partners convinced us to invest more effort in batch-level documentation and to integrate traceability tools for every batch produced.
The market sees room for shortcuts, and we see plenty of products that blend raw asparagine with magnetic or unspecified drying methods. We follow a slower crystallization protocol to foster purity and keep byproducts low. Every kilogram starts from pharmaceutical or higher-grade raw materials, followed by multi-stage filtration and recrystallization. We instituted extra washes using non-reactive, trace-minimized solvents after finding subtle contaminants in low-budget runs from other sources.
In batch production, we manage variables like temperature ramping and cooling rates because these factors directly influence the size and behavior of crystalline particles. Our standard batch might run for more hours than cheaper alternatives, but the outcome pays off during customer use. There are few surprises when opening fresh packages in real laboratory or processing conditions. Particle size uniformity translates to faster, more reproducible dissolving behavior; the water of hydration prevents unwanted static or dust.
Every researcher or production manager weighing options between DL, L, and D forms or between monohydrate and anhydrous grades will focus on technical fit. From our side, here are recurring questions we receive and observations we share with industry users:
Trace amounts of secondary amino acids, residual solvents, or unreacted starting materials can confound sensitive applications. We designed an integrated traceability system for batches, starting from incoming raw materials through to final QC and outgoing parceling. Every lot gets a chromatogram set that covers amino acid purity, hydration degree, and common contaminants. Our in-house analytics include amino acid analyzers and, for selected lots, mass spectrometry confirmation.
Third-party laboratories occasionally run spot-checks on our product, comparing our chromatograms to industry standards. Out of hundreds of tests, our DL-Asparagine Monohydrate sits comfortably in the 98.5 percent or higher purity range for total amino content, and our water content hovers within a tight window to label specifications. Rather than overshoot dryness, we found by experience that sticking precisely to the monohydrate level keeps the compound at peak stability after opening, avoiding rapid oxidation or discoloration.
One frequent question relates to shelf life. From our real-world tests, DL-Asparagine Monohydrate resists spoilage and decomposition under regular lab storage environments, provided it stays sealed and dry between uses. We use double-layer polyethylene and tamper-proof seals on all primary packaging to reduce frustration and risk. Based on monitoring, opened packs can serve up to a year without dip in measurable properties, so long as they’re not subject to repeated temperature and humidity cycling.
We routinely work with customers in warm, damp, or less-controlled processing facilities. Our product keeps its flow and measurement behavior—even where fridges run full or air conditioners sometimes falter. On rare occasions, we accommodate requests for custom packaging (smaller vials, moisture absorbers, secondary rigid cartons) for field researchers or those with especially sensitive storage needs.
DL-Asparagine Monohydrate’s track record in academic research keeps growing. One of our early university partners compared metabolic profiling in plant cells using DL- and L-forms. Their principal finding: the DL-form simplified baseline checks, especially in mutant or wild-type screens lacking isomer specificity. Researchers trust that with the monohydrate form, solutions reach expected concentrations without recalculating due to ambient humidity or hydration mismatch.
Industry users in the food sector layer the compound into standards for high-performance liquid chromatography and gas chromatography. Early on, a few overlooked the difference in hydration, leading to off-spec calculations, so we provide both digital and print guides for correct conversion. The tight composition control consistently passes internal checks—down to the detection of trace ions from glassware or vessel washings, which we filter out at production.
For biochemical manufacturing, such as in the production of custom oligopeptides, the monohydrate’s reliable mass and stability reduce batch failure rates. Notably, peptide chemists or those working on diagnostic kits reported that even minor impurities bug downstream coupling reactions, highlighting why we stick to stricter purification and filtration benchmarks than some rivals. Our clients tell us missed deliveries hurt less than failed experiments, so we keep our workflow aimed at consistency instead of chasing volume only.
Occasionally, we receive panicked requests from labs facing strange readings or product inconsistencies. Most of the time, these trace back to unlabeled or poorly documented reagent hydration. Staff turnover, language differences on packaging, or bad batch documentation created headaches. Our model uses laser-etched batch numbers and molecular hydration keys right on every bottle and carton, not just paper inserts, to keep the right information visible.
In one memorable case, a food lab in a tropical region experienced caked asparagine from a competing source, leading to misreadings in asparagine-dependent enzyme assays. They switched to our monohydrate batches and found their weighing and mixing hurdles vanished—no need to chop out clumps or estimate water absorption any more. The nature of the monohydrate, coupled with our dosing and shipment practices, helped stabilize their workflow for the next testing cycle.
Manufacturing isn’t static—we review our protocols every few years, using both customer input and our own troubleshooting data. We’ve tightened in-line monitoring of pH, filtered out more trace ions, and adopted analytics for even minor contaminants flagged in fast-evolving regulatory lists. Our cleaning regime for equipment grew from learning that even micro-residues—like cleaning agents or negligible amounts of process water outside specs—wreak havoc in ultra-sensitive preparations. These improvements don’t always show up in marketing copy, but our users encounter them in product reliability.
Labs placing large standing orders can request production schedules to coincide with their academic terms or trial cycles. We know research funding and industrial timelines don’t always match academic calendars or fiscal quarters, so our warehouse staff holds lots or customizes fulfillment to fit. We remain in contact about product performance, packaging preferences, and new regulatory developments shaping the world of amino acid ingredients.
Standing on factory floors and in QA labs, we see the connection between careful process design and what customers report back. By keeping complete build-to-ship traceability, consistent physical and chemical properties, and clear communication about form and hydration, we offer more than just an item code or product line slot. Years of solving small issues—such as shipping in the wet season, confirming label accuracy in multiple languages, and keeping up with constantly changing demand—means we see every order as a reflection of our long-term reputation.
Every batch of DL-Asparagine Monohydrate we ship carries the care, flexibility, and attention to detail that comes from chemical manufacturing at scale, not from simple repackaging. We know our place is not just in delivering a commodity, but in giving people the materials they need to do serious work—whether it’s the next round of food safety analysis, a challenging cell growth study, or a new industrial synthesis.