Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing sales7@sinochem-nanjing.com 3389378665@qq.com
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Dl-Arginine

    • Product Name Dl-Arginine
    • Alias Arginine
    • Einecs 205-538-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    346497

    Product Name Dl-Arginine
    Chemical Formula C6H14N4O2
    Molecular Weight 174.20 g/mol
    Cas Number 7200-25-1
    Appearance White crystalline powder
    Solubility Soluble in water
    Melting Point 222-225°C (dec.)
    Optical Activity Racemic mixture (DL-form)
    Ph Of 1 Solution 10.5-12.0
    Odor Odorless
    Storage Conditions Store in a cool, dry place
    Usage Laboratory reagent, supplement

    As an accredited Dl-Arginine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White plastic bottle with a blue screw cap, labeled "DL-Arginine, 100g," featuring hazard symbols and storage instructions in bold print.
    Shipping Dl-Arginine is shipped in airtight, sealed containers that comply with chemical safety regulations. During transportation, it is kept in a cool, dry environment away from incompatible substances. Packaging materials are selected to prevent contamination and moisture ingress, ensuring product integrity during transit and complying with local and international shipping standards.
    Storage Dl-Arginine should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers. It should be protected from moisture and direct sunlight. Ideally, storage should be at room temperature (15-25°C). Keep the container clearly labeled and ensure proper safety measures are in place to prevent contamination or accidental exposure.
    Application of Dl-Arginine

    Applications of Dl-Arginine in Industrial Manufacturing

    Dl-Arginine serves as a multifunctional intermediate and additive in several industrial sectors where strict formulation requirements and regulatory compliance dictate its use. We supply high-purity raw material directly to regulated downstream manufacturers, with technical support focused on process adaptation, consistent assay, and traceable supply for demanding production environments. Below, we outline specific industrial application scenarios based on verified uses, each with differentiated standards, addition ratios, process entry points, and resulting finished products.

    1. Pharmaceutical Formulation of Amino Acid Infusions

    Human parenteral nutrition solutions rely on precise blends of amino acids where arginine functions as a substrate for protein synthesis, nitrogen balance, and metabolic pathways. Integrators use Dl-Arginine as a cost-effective alternative in regions permitting racemic mixtures. Pharmaceutical producers must ensure exact ratios and comply with rigorous pharmacopoeias and sterile production controls. Our supplied Dl-Arginine features tailored particle size and trace impurity profiles for these critical integration steps, supporting high-batch consistency required by regulatory filings.

    Industry compliance standards

    • USP, EP, JP, and ChP pharmacopoeia monographs
    • GMP for Finished Pharmaceuticals (21 CFR Parts 210/211)
    • ICH Q3A/B for impurities and residual solvents
    • FDA and EMA guidance on amino acid injection quality

    Typical usage ratio

    • 1.0–2.0% w/v of total amino acid content (adjusted based on clinical formula and local maximum daily dosing)

    Downstream process integration

    • Incorporated at the aqueous solution preparation stage prior to sterilization, after filtration of bulk amino acid components, with filtered Dl-Arginine solution added to the blending tank before in-line mixing and aseptic filling

    Final product types

    • Single- and multi-chamber parenteral nutrition bags
    • Ready-to-use amino acid intravenous injection solutions
    • Pediatric and renal formula amino acid infusions

    2. Dietary Supplement Tablet and Powder Manufacturing

    Dl-Arginine, though less common than L-Arginine, receives use in food-grade tablet and powder nutritional products in regions permitting its inclusion. Nutraceutical companies require pharmacopeial or food additive grade, low-residue materials for direct compression or dry blend processes. Our manufacturing supports high bulk density grades optimized for free-flowing powder blends, consistently achieving low microbial and endotoxin levels demanded by dietary supplement Good Manufacturing Practices. Formulators choose addition levels according to functional claims and local market standards for amino acids in food applications.

    Industry compliance standards

    • US FDA 21 CFR Part 111 (Dietary Supplement GMPs)
    • EC 1925/2006 (EU addition of vitamins and minerals)
    • GB 14880 and GB 2760 for food additive use in China
    • EU Food Supplements Directive 2002/46/EC

    Typical usage ratio

    • 200–1000 mg per serving, dependent on product form (tablet, capsule, powder) and regional daily intake guidelines on amino acid dietary supplements

    Downstream process integration

    • Blended with micronutrients and excipients in batch dry mixers; for tablet lines, premixed blends enter direct compression; for powders, dosed in ribbon blenders before sachet or tub filling

    Final product types

    • Effervescent and chewable amino acid tablets
    • Sports nutrition drink powder premixes
    • Capsules for general health food supplements

    3. Cell Culture Media Production for Industrial Bioprocessing

    Downstream fermentation and biopharma producers utilize Dl-Arginine for metabolic support in non-GMP microbial and some mammalian cell culture systems. Bulk media producers demand amino acids meeting ISO 9001 and FAMI-QS criteria for low bioburden, consistent purity, and traceability. Manufacturers require precise solubility and rapid dissolution profile for liquid and powder formulations, supporting large-scale bioreactor runs. Our quality control ensures batch-to-batch reproducibility to minimize process variation impacting cell growth and recombinant protein yield.

    Industry compliance standards

    • ISO 9001 quality management systems
    • FAMI-QS for feed and industrial biotech additives
    • EHEDG hygienic design for media mixing facilities
    • QSAR/ECHA REACH notification for non-pharma amino acids

    Typical usage ratio

    • 0.02–0.1 g/L in finished growth media, calculated based on target cell line requirements and fed-batch protocol

    Downstream process integration

    • Dosed at dry blending or liquid concentrate preparation stage, ensuring powder fully dissolves before sterile filtration or direct tank addition in continuous feed systems

    Final product types

    • Powdered and liquid basal cell culture media
    • Industrial fermentation feeds for enzyme production
    • Bulk microbial protein manufacturing inputs

    4. Cosmetic and Personal Care Formulation

    Certain skin care brands deploy racemic arginine as a conditioning and humectant agent in leave-on and rinse-off products. Cosmetic formulators source cosmetic-grade amino acids qualified to IFRA and ISO 22716 for product safety and low allergen risk. Precise control of particle size and clarity ensures smooth emulsion texture and transparent hydrogel appearance. We support these customers with documentation for allergen status and process allergen controls.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 for cosmetic ingredients
    • ISO 22716 (Cosmetic GMP)
    • IFRA raw material guidance (where applicable)
    • Cosmetic Ingredient Review (CIR) safety assessments

    Typical usage ratio

    • 0.2–1.5% in facial serums and creams, selected based on viscosity, sensorial, and hydration targets for finished formulation

    Downstream process integration

    • Pre-dispersed in water phase or directly dissolved during emulsion preparation ahead of oil phase addition, followed by high-shear homogenization and pH adjustment

    Final product types

    • Hydrating gels and serums
    • Facial creams and emulsions
    • Shampoos and hair conditioners for salon and retail

    5. Animal Nutrition Premix Manufacturing

    Specialty feed and premix producers incorporate racemic arginine where permitted to balance non-essential and conditionally essential amino acid profiles, particularly in aquaculture and certain companion animal diets. Animal feed-grade Dl-Arginine must meet FAMI-QS, HACCP, and approved national registries. Production integrates continuous or batch mixing with strict cross-contamination controls to ensure compositional accuracy and bioavailability following extrusion or pelleting. Our validated supply chain guarantees consistent quality and reliable documentation for regulatory audits.

    Industry compliance standards

    • FAMI-QS for feed additives and premixtures
    • EU Regulation (EC) No 1831/2003 on feed additives
    • AAFCO (USA) feed ingredient definitions
    • HACCP systems for premix production

    Typical usage ratio

    • 0.05–0.15% of total feed mix; dosage is adjusted according to target species, stage of growth, and overall amino acid balance

    Downstream process integration

    • Added during dry mixing phase for premix or directly dosed into main extruder during pelleted feed manufacture, ensuring uniform dispersion before final packaging

    Final product types

    • Complete animal and aquaculture feed pellets
    • Custom feed additive premixes
    • Compound pet food blends for commercial distribution
    Free Quote

    Competitive Dl-Arginine prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    DL-Arginine: Meeting Quality Demands in Modern Industry

    Direct from the Manufacturer

    Every day in our production plant, we see tangible results from years spent refining the process behind DL-Arginine. Our plant brings raw materials into precise reaction, guided by process controls that technicians monitor around the clock. The finished product, DL-Arginine, rolls off the line as uniform white crystals, ready for application in a surprising range of industries—feeding research, pharma, and food sectors. There’s satisfaction in knowing each batch upholds the standards we set, drawn from years of feedback, real-world challenges, and practical lab analysis.

    DL-Arginine Model and Approach

    We produce DL-Arginine under the strict designation DL-Arginine, reflecting its status as a racemic mixture containing both D and L enantiomers. Laboratory technicians track optical rotation, HPLC retention times, purity shifts, and potential contaminants. Finished lots contain minuscule levels of moisture, and every kilogram meets a benchmark for heavy metals, microbial integrity, and foreign matter. We feed these benchmarks into software platforms for batch tracking, allowing us to check back on each completed run.

    Physical and Chemical Specifications

    In our formulation tanks, DL-Arginine takes shape as a stable white powder. It exhibits a clear solubility profile, mixing readily in aqueous media, yielding measurements that remain reproducible for both small and large volumes. Reactivity remains fairly mild under neutral conditions, giving users clear options for downstream blending or direct incorporation—one reason so many in food science and bioprocessing rely on this compound. Our technical team checks for melting point, bulk density, and granule finesse in every batch.

    A Trustworthy Ingredient for Many Sectors

    Over decades, we have shipped DL-Arginine to facilities around the world that use it in everything from amino acid blends to medical nutrition, injection grade solutions, tissue culture media, and new product prototypes. Many researchers value its consistency, especially in buffer systems and cell culture formulations. Food processors turn to DL-Arginine in protein fortification, functional beverages, and even sports nutrition products. Stability, clarity, and batch-to-batch reproducibility—those anchor not just our product, but the relationships we build with partners.

    Comparing DL-Arginine and L-Arginine

    DL-Arginine distinguishes itself from L-Arginine in both composition and application. L-Arginine is the pure biologically active enantiomer, playing a direct role in urea cycle metabolism, nitric oxide production, and protein synthesis in living organisms. DL-Arginine supplies both D and L forms, offering a broader chemistry for synthetic and technical uses but with a different physiological profile. Scientific papers note that D-Arginine does not contribute to biological pathways in the same way as L-Arginine, so chemists select DL-Arginine for technical purpose or as analytical standard, and L-Arginine when metabolic activity is essential.

    Many of our partners in chemical synthesis, diagnostic kits, and analytical labs ask for DL-Arginine when they need a stable, cost-effective source for experiments or controls, unconcerned with stereo-specific reactivity of biological systems. On the other hand, customers developing parenteral solutions, medical grade foods, or dietary supplements look for L-Arginine to match human metabolism. This fundamental chemical difference guides nearly every conversation we have with customers about which grade fits their project.

    Ensuring Reliability from Sourcing to Shipping

    From our perspective, reliability does not happen by chance. We built our production lines for batch consistency, starting with material checks as trucks unload raw amino acid precursors. Sensors and technicians verify the chemical profile of each incoming load, we maintain trace documentation, and digital logs follow lots through to finished goods. In-process testing spot-checks amino acid content, pH stability, moisture, and random contaminants, building a dataset for each lot.

    Shipping teams on the plant floor package DL-Arginine into moisture-resistant containers—double-walled bags, sealed drums, and cartons lined with desiccants where requested. We work with logistics partners experienced in handling sensitive, high-purity powders. Temperature and humidity controls reduce the risk of degradation, and documentation traces the journey from our site through to the customer’s dock. Consistent batch presentation, lot retention, and third-party lab validation anchor our approach.

    Applications: Practical Insights from Decades in the Field

    Looking back, we have seen DL-Arginine used in countless novel experiments. Proteomics teams in Europe have sourced our DL-Arginine for calibration standards and stability testing. Food scientists in Asia validate salt blends, meat analogs, and fortification strategies using our product; they report a stable shelf life and predictable flavor interaction. Biotechnology start-ups often request technical grade DL-Arginine for use in new enzyme formulations—taking advantage of its solubility and clean impurity profile.

    Researchers operating tissue culture labs often prefer DL-Arginine for non-metabolically active assays where the racemic property fits the need, including model system testing and in vitro protocols not constrained by biological uptake. In contrast, teams focused on therapeutic or nutritional intervention turn toward L-Arginine, underlining how application shapes the choice. DL-Arginine’s broad chemical profile enables it to serve in catalyst preparation, pH buffering systems, and many small molecule syntheses. By acting as both a building block and a comparison standard, it finds niche use in materials science as well, where only technical performance matters.

    What Sets Our Process Apart

    Manufacturing amino acids day in and day out, we see firsthand that DL-Arginine quality comes down to process control and a hands-on approach. We source raw materials from vetted suppliers, conduct on-site quality audits, and hold them to rejection thresholds that screen out inconsistent lots. During synthesis, our reactors bring in controlled amounts of ammonia, cyanamide, or other reagents in precise pH, monitored by older but trusted glass electrodes and new automation panels alike.

    Batch leaders analyze in-progress samples, testing for unreacted precursors, intermediate byproducts, and finished DL-Arginine content. Process control teams make fast decisions—sometimes adjusting pH or process time by just a hair to avoid yield loss or slight contamination. Workers document observations, and plant safety protocols keep airborne dust to a minimum, preserving both product quality and employee well-being. These steps form the backbone of DL-Arginine manufacturing, built on decades of real-world troubleshooting and laboratory follow-up.

    Final purification brings the crystalline structure to specification, using vacuum drying, sieving, and double packaging. By the time DL-Arginine leaves our loading dock, every drum has undergone more than half a dozen QC checks, including those for heavy metal content, microbiological safety, and trace contaminants that even customer labs rarely test. These investments protect the product at every step, responding to exporter requirements in the EU, United States, and Asia-Pacific. We keep customer feedback loops active—site visits, technical calls, and sampling rounds each year allow us to listen and improve.

    Changes in Regulations and Market Demand

    Regulatory standards for amino acids never stop evolving. We track changes from major Health Authority bulletins, trade partners, and customer feedback. In recent years, stricter guidelines emerged around permissible heavy metal content, labelling requirements, traceability, and imported food additives. Our response means tweaking everything from material acceptance procedures to updating labeling and batch tracing software. The lab team adapted their analytical methods, picking up new reference standards to detect parts-per-million or lower of possible contaminants.

    Market demand, too, keeps us humble. Ten years ago, pharmaceutical and clinical companies made up much of our DL-Arginine business; today, new entrants from sports nutrition, plant protein systems, and animal-free food are asking tough questions about suitability. We run customer audits at our site, answering questions face to face about every step from raw sourcing to final drum inspection. This means transparency and openness—a willingness to share documentation, invite inspections, and sometimes rebuild process steps when a new supplier or compliance regime demands it. The pressure for higher quality, better documentation, and faster delivery continues to shape our manufacturing environment.

    Supporting Responsible and Sustainable Practices

    As a producer, our choices ripple through supply chains—affecting water use, energy consumption, and waste generation. Over the past few years, we invested in waste water treatment plants, energy-efficient lighting, and improved solvent reclamation. We moved from single-use packaging to clean, recyclable containers where possible. We also audit our key chemical suppliers for waste handling, child labor policies, and safety training, using a supplier scoring system to push improvements upstream.

    Customers in the EU and North America increasingly ask for evidence of green practices, carbon footprint tracking, and responsible material choice. We expect this trend to grow, and our process teams actively seek out solvent reduction and greener synthetic alternatives. Where old methods produced high-waste runoff, we experimented with inline filtration and recapture, reducing downstream environmental risk. Maintaining trust means showing a clear chain of responsibility and continual steps toward cleaner manufacturing.

    Common Questions from Partners and Customers

    Long-term customers often reach out with practical concerns that reveal how DL-Arginine functions in real-world settings. One end user noticed variation in solution clarity at high concentrations. After on-site review and sample exchange, we discovered a minor uptick in sodium content from a change in secondary raw material supply. After feedback and batch investigation, we retuned that supply chain to remove the cause. Another incident involved material caking in high-humidity regions—so we redesigned our drum packaging, switching to twin-layer liners and including silica desiccant packs inside every unit.

    Analytical labs asked about batch-to-batch consistency, especially regarding trace elements and microbial counts. Our solution: move toward automated batch tracking, with record accessibility for sample-by-sample comparison. Over time, this investment paid off in fewer support calls and improved trust during partner audits. Customer feedback also pointed to a preference for certain mesh sizes. While the bulk product comes in a standard granule format, we now maintain a separate production line for fine powder, meeting niche requirements for rapid dissolution in biotech and diagnostics.

    Facing Supply Chain and Quality Challenges

    Our experience shows that supply chains remain vulnerable to raw material disruptions, shipping slowdowns, or regulatory reviews. During a recent global logistics crisis, key reagent supply slowed, and production lines adapted by switching to alternative qualified sources that matched our primary specification sheets. Our technical group shifted to faster analytical checks during material qualification, ensuring every substitute input matched downstream application needs.

    Audits by both local authorities and major food multinationals reinforced the importance of transparency and rapid communication. To address this, we offer full specification sheets, track lot numbers in an accessible digital format, and run retained sample checks for up to five years post dispatch. In situations where end product batches showed abnormal readings, root cause analysis began by revisiting the original qualification batch data—a habit born from years of troubleshooting under pressure.

    Close Ties with the R&D Community

    We work closely each year with academic researchers, formulation chemists, and QA professionals from large food and pharma groups. These exchanges bring R&D teams on site, encourage open dialogue, and sometimes spark changes in process flow, drying methods, or packaging. Through collaborative trials, we’ve improved dissolution rates, reduced off-flavor contributions, and tested alternative purification steps aimed at next-generation diagnostic or bioprocessing goals.

    Many end users share their findings with us, from solubility studies and stability monitoring to clinical trial results and application feedback. This two-way exchange has built a robust technical database, helping us flag potential issues before they hit broader production. Storing and referencing these shared results means that questions from new partners get authoritative, real-world answers, not just literature citations. Our own in-house R&D group keeps pilot reactors and analytical benches constantly busy, replicating partner applications when new requests come in.

    Looking Ahead: DL-Arginine’s Ongoing Role

    In the big picture, DL-Arginine remains a workhorse molecule for sectors ranging from pure chemistry to applied food science. Its blend of affordability, chemical consistency, and broad technical grade characteristics keeps it in demand, even as specialty amino acids and biotech-driven peptides emerge. As processes upgrade, we continue investing in tighter analytical protocols, cleaner raw materials, and more reliable packaging. Partners can expect the same direct access to our technical teams, complete documentation, and support during audits or trials, as they have for decades.

    Many in the field ask what makes a reliable amino acid supplier. From our side of the fence, it is a willingness to invest in process, documentation, and continual feedback—staying flexible in the face of regulatory, supply, and technical shifts. We see evidence of this every year, from raw materials delivered to our gate, through production, and into customer application labs worldwide.

    Those searching for an ingredient that pairs certified purity with broad chemical versatility continue to put DL-Arginine at the top of their list. We take the job of keeping that promise seriously, shaped by years at the production line, in the lab, and working directly with customers old and new.