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DL-Alpha-Amino-Epsilon-Caprolactam

    • Product Name DL-Alpha-Amino-Epsilon-Caprolactam
    • Alias 6-Aminocaproic acid lactam
    • Einecs 254-473-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    806469

    Product Name DL-Alpha-Amino-Epsilon-Caprolactam
    Chemical Formula C6H10N2O
    Molecular Weight 126.16 g/mol
    Cas Number 3392-97-0
    Appearance white to off-white crystalline powder
    Melting Point 190-194 °C
    Solubility In Water soluble
    Purity typically ≥98%
    Storage Conditions store at room temperature, keep container tightly closed
    Synonyms DL-2-Aminocaprolactam, 6-Amino-2-azepanone
    Boiling Point decomposes before boiling
    Pka 8.7 (amino group)
    Structural Class Lactam, amino acid derivative
    Application intermediate in chemical synthesis

    As an accredited DL-Alpha-Amino-Epsilon-Caprolactam factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed plastic bottle containing 500 grams of DL-Alpha-Amino-Epsilon-Caprolactam, labeled with product details, hazard warnings, and batch number.
    Shipping DL-Alpha-Amino-Epsilon-Caprolactam is shipped in tightly sealed, corrosion-resistant containers to prevent moisture and contamination. Packages are clearly labeled according to regulatory standards. The chemical is transported under ambient conditions, away from incompatible substances. All shipments comply with relevant transportation regulations to ensure safe and secure delivery to the destination.
    Storage DL-Alpha-Amino-Epsilon-Caprolactam should be stored in a cool, dry, well-ventilated area, away from direct sunlight and sources of heat or ignition. Keep the container tightly closed and properly labeled. Avoid exposure to moisture and incompatible materials such as strong oxidizing agents. Store at room temperature and handle in accordance with good industrial hygiene and safety practices.
    Application of DL-Alpha-Amino-Epsilon-Caprolactam

    Applications of DL-Alpha-Amino-Epsilon-Caprolactam in Industrial Manufacturing

    We supply DL-Alpha-Amino-Epsilon-Caprolactam to industrial producers worldwide, supporting precise downstream integration for high-value manufacturing. Below, we detail key application scenarios with specific regulatory, formulation, and processing backgrounds that align with the demands of the industries we serve.

    1. Peptide Synthesis Intermediates for Pharmaceutical APIs

    Pharmaceutical manufacturing relies on this compound as a protected amino acid building block in automated solid-phase peptide synthesis (SPPS) and solution-phase peptide assembly for active pharmaceutical ingredient (API) processes. The material’s structural properties allow for selective peptide chain elongation, supporting the synthesis of specialty oligopeptides and cyclic peptides for oncology, metabolic, and rare disease treatments, which require high optical and chemical purity assured by critical quality control procedures.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for APIs
    • European Pharmacopoeia (Ph. Eur.) 10.0 / United States Pharmacopeia (USP) specifications for amino acid derivatives
    • FDA 21 CFR Part 210/211 for pharmaceutical manufacturing
    • ISO 9001:2015 Quality Management Systems

    Typical usage ratio

    • 0.10–0.25 molar equivalents per peptide bond formed; adjusted based on peptide length and protecting group protocol

    Downstream process integration

    • Incorporated during sequential amino acid coupling cycles on automated synthesizers or flow reactors at resin or liquid phase coupling steps

    Final product types

    • API-grade therapeutic peptides
    • Research peptides for preclinical studies
    • Cyclic peptide intermediates
    • Drug conjugate precursors

    2. Chiral Intermediate for Fine Chemical Synthesis

    The compound contributes as a chiral building block in the synthesis of optically active intermediates for agrochemicals, specialty chemicals, and advanced materials. Its well-defined stereochemistry makes it valuable for precise diastereoselective and enantioselective transformations, minimizing racemization risks in downstream reactions where chirality directly impacts end-use performance and product registration efficacy.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for chemical registration in the EU
    • ISO 14001:2015 Environmental Management Systems
    • GHS/CLP chemical labeling and safety requirements
    • Local jurisdictional chemical inventories (e.g., TSCA, ENCS, K-REACH)

    Typical usage ratio

    • 0.05–0.20 moles per mole of target intermediate; ratios depend on desired chirality and stepwise reaction selectivity

    Downstream process integration

    • Utilized in key asymmetric synthesis or resolution steps, such as organocatalytic or biocatalytic transformations in batch or continuous flow reactors

    Final product types

    • Enantiopure agrochemical actives
    • Chiral ligands and specialty chemical intermediates
    • Advanced polymer precursors
    • Photoinitiators for electronics and 3D printing segments

    3. Monomer Modifier in Polyamide Engineering Plastics

    In polyamide resin manufacturing, this caprolactam derivative is introduced to tailor molecular weight distribution and modify end-group functionality during polymerization, enhancing physical properties like toughness, viscoelasticity, and melt processability for engineered components in the automotive, electrical, and industrial equipment sectors. Controlled addition allows custom performance profiles in high-specification molding compounds.

    Industry compliance standards

    • ISO 1874-1: Polyamide (PA) molding and extrusion materials specification
    • UL 94 Flammability Standard for Plastics
    • RoHS Directive 2011/65/EU (for electronics)
    • Automotive OEM technical approval lists (e.g., VW TL, GM GMW)

    Typical usage ratio

    • 0.01–0.10 wt% based on total monomer feed; determined by final molecular weight target and additive compatibility

    Downstream process integration

    • Added at the initial monomer charge or during pre-polymerization to adjust chain length and functional end-groups in bulk polymerization or continuous melt processes

    Final product types

    • Glass fiber reinforced nylon 6/6 composites
    • Automotive connectors and housings
    • Industrial cable sheathing
    • Electronic component encapsulations

    4. Intermediate in Biochemical Research Reagents

    Biotechnology laboratories and reagent manufacturers use this material as a key building block for the custom synthesis of tagged amino acid derivatives, fluorescent probes, and peptide-based bioassay substrates. Its functional versatility allows selective chemical modification, supporting structure-activity studies and development of molecular probes required for high-throughput screening and diagnostic kits.

    Industry compliance standards

    • ISO 13485:2016 for medical device and diagnostic reagent quality
    • IUPAC guidelines for chemical nomenclature and purity reporting
    • OECD Good Laboratory Practice (GLP) for research chemicals
    • Local biosafety handling policies

    Typical usage ratio

    • 0.01–0.05 molar equivalents per labeling or tagging reaction, typically controlled by substrate accessibility and detection method requirements

    Downstream process integration

    • Incorporated during synthetic modification or peptide labeling steps utilizing solution-phase or solid-phase synthesis equipment

    Final product types

    • Fluorescently labeled peptides
    • Selective assay substrates for enzyme detection
    • Bioactive peptide conjugates
    • Functional molecular probes for cell imaging

    5. Precursor for Specialty Surfactant Synthesis

    Select manufacturers use this compound to construct amino-functional surfactant molecules for applications in emulsification, antistatic agents, and advanced cleaning agent formulations, where its cyclic backbone confers distinct hydrophilic-lipophilic balance (HLB), chemical stability, and controlled release profiles required in electronics, textile, and high-purity process industries.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals (biodegradability and eco-toxicity)
    • EN 12764: Surfactants for industrial cleaning
    • ISO 9001:2015 Quality Management Systems for specialty chemicals
    • REACH Registration for environmental and human health assessment

    Typical usage ratio

    • 5–15% by weight in reaction formulations for surfactant backbone construction, adjusted by target HLB and application demands

    Downstream process integration

    • Integrated at the alkylation, amidation, or acylation stage during batch or semi-continuous surfactant synthesis

    Final product types

    • Amino-terminated antistatic agents for electronics
    • Emulsifiers for high-purity process fluids
    • Performance textile softeners
    • Specialty detergents for microelectronics cleaning
    Free Quote

    Competitive DL-Alpha-Amino-Epsilon-Caprolactam prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    Understanding DL-Alpha-Amino-Epsilon-Caprolactam: Expertise from the Manufacturer’s Floor

    How DL-Alpha-Amino-Epsilon-Caprolactam Fits into Modern Chemical Manufacturing

    Working with DL-Alpha-Amino-Epsilon-Caprolactam each day in our facility, we’ve seen what it takes to move from lab curiosity to industrial backbone. This compound, commonly referenced by its chemical nomenclature rather than market branding, brings real versatility into synthesis lines where both efficiency and performance outweigh slogans and trends. Our daily challenges revolve around purity, safe handling, and consistent reactivity. These factors mean more to us than marketing points—they directly shape outcomes for each client counting on repeat results.

    Model and Specifications: Attention to What Matters in the Plant

    We produce DL-Alpha-Amino-Epsilon-Caprolactam in batches ranging from pilot scale upwards, targeting industry-standard specifications with precise control. You won't find boutique models with shifting formulations; this product has a defined molecular structure—C6H12N2O—with strict attention to chiral purity and minimal byproducts. Our output runs at greater than 99% purity, verified every shift using HPLC and NMR. Our technical teams document physical properties at each stage, making sure the final product meets workable melting, solubility, and stability ranges.

    Attention to moisture content and residual solvent levels remains high because these factors impact downstream applications, like peptide synthesis or specialty polymer manufacturing. Powder flow, granule sizing, and packaging integrity get far more scrutiny than customers often see; these details eliminate surprises, which cuts costly downtime mid-process. We listen closely when clients report back on performance, adapting processes with direct feedback rather than guesswork.

    The Day-to-Day Use of DL-Alpha-Amino-Epsilon-Caprolactam in Industry

    In our daily experiences, most questions we field from chemists or process engineers revolve around the practical realities of using and storing this lactam. We routinely load tankers, fill drums, and consult on reactions that use DL-Alpha-Amino-Epsilon-Caprolactam as a building block. In peptide coupling, its reactivity and selectivity bring a streamlined step to forming robust bonds. The lactam ring offers reactivity distinct from linear amino compounds, giving manufacturers a tool for introducing specific configurations within longer chains.

    Discussions with clients run beyond simple supply. Some synthesize advanced polymers for biomedical applications, counting on our consistency batch to batch. Others require small-volume high-purity for investigative research into new bioactive molecules. In every field, trace contaminants make all the difference, so our laboratory analyzes for metallic ions and organic residues down to the ppm level. The perspective from our manufacturing team: every additional purification adds cost, but shaving corners never brings lasting business. We hold to protocols that deliver what long-term partners expect, not what fits a spreadsheet for a single quarter.

    Comparisons: DL-Alpha-Amino-Epsilon-Caprolactam Versus Other Building Blocks

    There’s no shortage of caprolactam derivatives on the market—you’ll see similar names, but the differences run deeper than catalog numbers. Working hands-on, we see a clear split: natural L-forms, D-forms, racemic mixtures like DL, and the impact each has on target molecules. Synthetic decisions matter most at the bench, not in copywriting. For researchers requiring strictly chiral intermediates, we help source or produce single-isomer versions, but in many polymer or bulk organic processes, the racemic DL-Alpha-Amino-Epsilon-Caprolactam answers the need for cost efficiency without sacrificing function.

    As opposed to classic epsilon-Caprolactam—well-known as the monomer for nylon 6—DL-Alpha-Amino-Epsilon-Caprolactam features an extra amino group, giving it dual functionality. This redesign opens new reaction pathways not accessible to standard caprolactams. For example, while classic caprolactam polymerizes via ring opening to deliver strong, versatile polyamides, DL-Alpha-Amino-Epsilon-Caprolactam enables selective functionalization points within peptide chains or specialty resins. This property has pushed innovation in adhesive materials and biomedical research alike.

    Quality and Consistency: Our Shop Floor Perspective

    In our plant, quality does not mean a simple certificate attached at the end, but a chain of decisions and checks at every step. We control raw materials from vetted suppliers and run in-process testing on each batch. Our reactors have seen thousands of cycles, and our operators know when a curve strays from normal. When temperature or pH drift, they don’t leave it to automated warnings; experience fills the gaps that sensors can’t catch. Day-to-day, it’s about catching the small signals—an unexpected color, slight viscosity change, or shift in crystallization—before they become problems.

    Some customers have shifted from smaller, overseas labs where batch sizes are inconsistent or surprise variability creeps in. In our experience, transparency with clients builds the kind of trust that brings repeat business. We aim to share detailed COAs with every shipment, not just to tick off a box, but to help downstream chemists make informed decisions. When customers talk about trace impurity spikes, we circle back to our plant technicians, check logs, and adjust controls. This continuous improvement closes the loop between production and application.

    International standards become real on our floor: ISO batch logging, cross-validated analysis, lot traceability. For us, it’s not a marketing line. Regulatory customers visit in person or virtually, walking the same aisles as our operators. We welcome challenging questions because we have data hand-written in logs, not just in the ERP.

    Operational Challenges and Problem-Solving on the Production Line

    DL-Alpha-Amino-Epsilon-Caprolactam comprises a stable enough molecule to ship worldwide, but it brings its own quirks. Left exposed, its amino group can invite moisture, so we maintain strict desiccation throughout the filling lines. Our plant humidity sensors link directly with line shutdowns, not just alarms, so the product retains its shelf-stable state all the way to the user. Loading into drums takes trained hands who understand that a moment of rushing can break a seal and compromise a whole batch.

    We’ve faced problems: a supply chain interruption in precursors, a hard freeze during winter shipping, or customer returns when packaging fails. Each incident demanded more than just a memo—we analyzed root causes, then retrained staff and tweaked equipment. For example, our experience with a cold storage breakdown led us to retrofit additional insulation and backup power for every holding tank. When a customer found an off-odor in the product, we ran a full traceback, finding a microcontaminant in a raw feedstock. That single event led us to change suppliers. These lessons stick, shaping not just process but mindset.

    Customer Feedback: Real Impact in Labs and Production Sites

    We don’t sell on packaging or superficial claims. Many of our customers return year after year because in their hands, batch reactivity matches what they expect. We count site visits and phone calls as routine, not as escalation—clients walk through our plant, see the product run through our analytic suite, and discuss new synthesis challenges long before they commit to an order. We keep channels open so chemists and buyers get straight answers to technical questions, not talking points filtered through multiple layers.

    We see our product tested in peptide synthesis for pharmaceuticals, in R&D pilots for bio-resorbable plastics, and in specialty adhesives that need both strength and biocompatibility. Reports of high conversion rates or precise coupling steps carry more weight to us than bundled marketing metrics. If a product sits unsatisfied on a shelf, we call in to find out why—sometimes the answer lies in a seemingly minor difference, like packing density or a change in drum lining. Every formal complaint means a learning opportunity, and over the past decade, that feedback has shaped everything from storage recommendations to the way we label every container.

    DL-Alpha-Amino-Epsilon-Caprolactam and Sustainable Manufacturing

    Every manufacturer feels pressure to reduce waste, lower emissions, and increase safety. For us, this is practical reality, not a checkbox for compliance. We monitor every solvent stream and recycle where purity allows; our distillation trains keep waste to a minimum, both for economic and environmental impact. We measure not just emissions, but water, energy, and solvent consumption per kilo of product.

    Some customers ask for green chemistry certifications or low-residue versions, especially when downstream processes feed into biomedical or food contact applications. Our team has piloted new filtration and purification methods that lower the use of harsh solvents and optimize energy consumption during drying stages. For more sensitive uses, we invest in extra steps—sometimes at the cost of throughput—to ensure no carryover of undesirable process aids. Dialogue with forward-thinking partners helps us test and scale up these greener improvements in real manufacturing settings, not just on the whiteboard.

    Technical Innovations and the Future of this Chemical Family

    The chemistry behind DL-Alpha-Amino-Epsilon-Caprolactam comes alive with current research into new bioactive scaffolds, medical devices, and specialty copolymers. R&D teams have tested this compound as a synthon for site-specific attachment in targeted therapies, as well as a functional intermediate for advanced adhesives and coatings. Each shift our teams adapt process variables to meet specific requirements, sometimes introducing new purification or drying steps at the request of development partners.

    Collaborative research yields changes to the way we test, package, and record batches. Structured feedback from external labs drives process tweaks—altering crystal size distribution, for instance, or fine-tuning moisture content to mesh with automatic feeders in high-throughput lines. Real progress comes not just from theory but repetition: small improvements that, multiplied by thousands of kilos per year, lead to scaled-up efficiencies for everyone. Keeping close partnerships with academic and industrial researchers lets us stay just ahead of new regulations and emerging markets.

    Safety from the Manufacturer’s Viewpoint

    Routine handling inside our facility requires more than checklists. Training extends from the shop floor to the packaging line, focusing on real risks: safe containment, operator PPE, rapid containment in case of a spill. We share best practices for storage and transport directly with the logistics teams that move our barrels and containers so those best practices extend all the way to the customer’s dock.

    As regulations change, we update labels, SDS, and internal procedures in step—not weeks behind. This means no delays for clients during site inspections or regulatory reviews. We see safety as more than compliance; every near-miss on our floor prompts an incident review and follow-up, aiming to prevent not just repeat mistakes but new vulnerabilities. For shipments crossing borders, our records and packaging materials meet all the current requirements for safe and secure transit.

    What Sets a Manufacturer Apart: Experience and Commitment

    Biggest difference our team brings is experience, up and down the line. Many of our lead operators started with us as apprentices or interns; they know each reactor’s quirk, each filtration train’s normal hum. Training never ends here: we mentor the next generation of process engineers, so proven protocols and quick troubleshooting skills carry over—even as we introduce automation and upgraded analytics. Mistakes made years ago shift plant policy for everyone, not just for a manager’s memo.

    Direct relationships with customers mean that changes in demand, unusual technical requirements, or urgent orders can be managed with minimal fuss. We’ve weathered surges and slumps, shifting production volumes up or down in response to client needs and market signals. Tighter timelines or new application approvals always mean a review of capacity, safety, and QC procedures—not a shortcut. Long-term success sits with manufacturers who listen, adjust, and keep promises.

    Looking Forward: Opportunities for Innovation in the DL-Alpha-Amino-Epsilon-Caprolactam Value Chain

    Growth in demand for DL-Alpha-Amino-Epsilon-Caprolactam often follows trends in pharmaceuticals, biopolymers, or advanced coatings. Adaptability in manufacturing—pivoting stair-step volumes, switching between purity grades, or running test batches for client R&D—spells the difference between partnership and commodity supply. Our team talks directly with innovators: we hear early about process changes, regulatory pressures, and new uses for this compound beyond what the textbooks offer.

    Future improvements in our own process will likely come from greener chemistry and better integration with downstream analytics. Rapid advances in mass spectrometry and online process monitoring now let us catch quality issues before they leave the plant. Customer audits, once a source of anxiety, have shifted to collaborative opportunities—reviewing trends in process data, sharing learnings both ways.

    Each year, we see new patents and technical reports calling for DL-Alpha-Amino-Epsilon-Caprolactam as an enabling reagent; each brings opportunities for adaptation on our side. Our response remains the same: act on solid feedback, invest in infrastructure, and keep technical know-how close to the reactor floor. That’s the surest path to excellence in manufacturing.