Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Disodium Hydrogen Phosphate Dihydrate

    • Product Name Disodium Hydrogen Phosphate Dihydrate
    • Alias Disodium Phosphate Dihydrate
    • Einecs 231-448-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    203586

    Chemical Name Disodium Hydrogen Phosphate Dihydrate
    Chemical Formula Na2HPO4·2H2O
    Molar Mass 177.99 g/mol
    Appearance White crystalline powder
    Solubility In Water Efficiently soluble
    Ph In Solution 8.0-11.0 (1% solution at 25°C)
    Melting Point Disassociates before melting
    Density 1.52 g/cm³
    Cas Number 10028-24-7
    Ec Number 231-448-7

    As an accredited Disodium Hydrogen Phosphate Dihydrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White HDPE bottle, tightly sealed, labeled "Disodium Hydrogen Phosphate Dihydrate, 500g, Analytical Reagent, Store cool and dry, CAS 10028-24-7."
    Shipping **Disodium Hydrogen Phosphate Dihydrate** should be shipped in tightly sealed containers, protected from moisture and incompatible substances. Store in a cool, dry, well-ventilated area away from acids. Typical shipping is not regulated as hazardous material, but proper labeling and documentation are required. Handle with appropriate chemical safety precautions during transport.
    Storage Disodium Hydrogen Phosphate Dihydrate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area. Keep it away from incompatible substances like strong acids. Protect from moisture and direct sunlight. Ensure storage areas are labeled appropriately and prevent contact with combustible materials. Follow all relevant safety guidelines and local regulations for chemical storage.
    Application of Disodium Hydrogen Phosphate Dihydrate

    Applications of Disodium Hydrogen Phosphate Dihydrate in Industrial Manufacturing

    As a direct manufacturer of Disodium Hydrogen Phosphate Dihydrate, we supply high-purity material to leading producers across several established industrial sectors. Our technical knowledge and experience support critical roles for this phosphate in diverse manufacturing environments, each governed by precise specifications and process controls to ensure safety, consistency, and compliant product performance.

    1. Food and Beverage Processing: pH Control and Buffering Agent

    Food processors rely on Disodium Hydrogen Phosphate Dihydrate as a buffering salt to maintain stable pH in batch and continuous blending lines for products such as processed cheeses, powdered soups, and instant pudding mixes. The compound's consistent and predictable phosphate contribution ensures stable protein function and shelf-life, directly supporting organoleptic properties and regulatory food safety standards. Processing teams monitor analytical pH and adjust addition levels based on ingredients, regional compliance, and end-product targets.

    Industry compliance standards

    • Codex Alimentarius (Food Additive INS 339(ii))
    • US FDA 21 CFR 182.6778 (GRAS for direct food use)
    • EU Regulation 231/2012 (E339(ii) Food Grade)
    • GB 2760-2014 (China Food Additives Standard)

    Typical usage ratio

    • 0.1%–1.5% by weight, adjusted depending on specific product formulation, target pH, and local regulatory limits

    Downstream process integration

    • Added during pre-mixing or initial hydration stages in dairy and beverage plants
    • Functionally integrated with phosphates and caseinates in cheese-making cookers
    • Incorporated in blending tanks before thermal processing in instant soup lines

    Final product types

    • Processed cheese slices and spreads
    • Powdered instant soups and broths
    • Non-dairy creamer powders
    • Baking powders for cakes and pastries

    2. Water Treatment: Boiler Water Conditioning and Scale Inhibition

    Industrial water treatment facilities dose Disodium Hydrogen Phosphate Dihydrate during condenser and boiler feedwater conditioning to control pH, precipitate hardness ions, and limit scale formation on heat exchange surfaces. Engineering teams calculate dosing based on inflow water quality and system load profiles, preventing corrosive conditions and optimizing system life-cycle performance. The compound helps stabilize alkalinity, supporting continuous operation in power stations and process industries.

    Industry compliance standards

    • ASME Boiler and Pressure Vessel Code (Boiler Feedwater Quality)
    • ASTM D511 (Phosphate Testing in Water)
    • Industrial boiler codes for treated feedwater, such as BS 2486 (UK) or GB/T 12145 (China)
    • Internal corporate water chemistry guidelines

    Typical usage ratio

    • 5–50 mg/L of feedwater, with specific dosing based on water hardness, alkalinity, and operational cycles

    Downstream process integration

    • Automated injection into deaerators or feedwater lines prior to entry into steam generation units
    • Continuous monitoring and make-up by plant chemists via dosing pumps linked to online water analysis

    Final product types

    • High-pressure steam for electric turbines
    • Industrial process water with controlled mineral content
    • Conditioned water for closed-loop heating/cooling circuits

    3. Detergent and Cleaning Agent Manufacturing

    Detergent formulators use Disodium Hydrogen Phosphate Dihydrate as a builder and alkalinity source, optimizing cleaning efficiency in institutional and household powder detergents. It facilitates soil suspension, water softening, and the stabilization of surfactant blends during batch mixing and granulation. Quality assurance teams verify phosphate composition in each batch to satisfy strict regulatory limits while achieving washing performance in challenging water conditions.

    Industry compliance standards

    • EU Regulation (EC) No 648/2004 (phosphate limits in detergents)
    • US EPA Safer Choice Program Guidance
    • China’s GB/T 13171 (Synthetic Detergents Standard)
    • ISO 9001:2015 (Quality Management Systems for chemical plants)

    Typical usage ratio

    • 2%–8% by formula weight; lower ranges for automatic dishwashing, higher for industrial powder cleaners, adjusted for regional phosphate restrictions

    Downstream process integration

    • Introduced during blending of base powder with surfactants and other builders
    • Mixed and granulated prior to spray-drying in powder detergent manufacturing

    Final product types

    • Household laundry powders
    • Commercial dishwashing powders and tablets
    • Industrial surface cleaners for food processing equipment

    4. Pharmaceutical Formulation: Tablet and Liquid Buffer Systems

    In pharmaceutical production, formulation chemists incorporate Disodium Hydrogen Phosphate Dihydrate to regulate pH in oral and injectable medications, particularly as a component of phosphate buffer systems. Process engineers rely on its defined hydration and solubility profile to maintain precise active ingredient stability, and batch records detail each addition step to secure traceability for regulatory audits. Release to downstream encapsulation or vial filling lines occurs only after in-process QC confirms compliance with pharmacopoeial requirements.

    Industry compliance standards

    • USP-NF (United States Pharmacopeia; monograph for Sodium Phosphate Dibasic)
    • Ph. Eur. (European Pharmacopoeia, Sodium Hydrogen Phosphate)
    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • WHO GMP Guidelines

    Typical usage ratio

    • 0.05%–0.5% by weight in solid dosage forms; 5–100 mmol/L in injectable or ophthalmic solution buffers

    Downstream process integration

    • Added during wet granulation for tablets or dissolved in buffer solution tanks before sterile filtration in injectables manufacturing
    • Documented control of pH during blending or dissolution to ensure pharmacopoeial compliance

    Final product types

    • Buffered saline solutions for parenteral administration
    • Oral solid dosage forms (e.g., tablets, capsules)
    • Diagnostic reagent kits

    5. Laboratory Reagent and Chemical Analysis

    Analytical laboratories make use of our disodium hydrogen phosphate dihydrate for the preparation of calibration and buffer solutions, which are essential for pH meters, titration assays, and diagnostic kits. Because accurate, repeatable measurements depend on buffer integrity, established QC protocols require traceable sourcing and batch-specific COAs. Integration typically takes place at the reagent preparation phase, supporting downstream titrimetric and spectrophotometric determinations where phosphate consistency is critical.

    Industry compliance standards

    • ISO/IEC 17025 Laboratory Accreditation
    • ASTM E2876 (Phosphate Buffer Solutions for Laboratory Analysis)
    • Pharmacopeial references for test solution preparation (USP, Ph. Eur., BP)
    • GLP (Good Laboratory Practice) regulations

    Typical usage ratio

    • Formulates standard buffer solutions at concentrations such as 0.1 M or 0.2 M, precise to the protocol’s calibration point

    Downstream process integration

    • Dissolved into deionized or ultra-pure water for buffer or test solution preparation
    • Integrated into auto-analyzer or manual assay setup prior to measurement procedures

    Final product types

    • pH calibration buffer solutions (e.g., pH 7.0, 7.2, 7.4)
    • Standard reference solutions for ion chromatography
    • Diagnostic test reagent kits for clinical and research laboratories
    Free Quote

    Competitive Disodium Hydrogen Phosphate Dihydrate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Disodium Hydrogen Phosphate Dihydrate: A Manufacturer’s Perspective

    Understanding Disodium Hydrogen Phosphate Dihydrate

    From years on the shop floor and in the development lab, I’ve seen firsthand just how crucial the details can be with compounds like disodium hydrogen phosphate dihydrate. Chemists know it as Na2HPO4·2H2O, but those of us making and supplying the material see it less as a formula and more as a workhorse. With its white, crystalline appearance and stable behavior under typical warehouse conditions, this salt supports countless applications that call for both reliability and consistency.

    We produce disodium hydrogen phosphate dihydrate in batches that match high-purity requirements, most often with specifications aligned to analytical and technical grade needs. These grades stem from rigorous process controls in the manufacturing pathway—distinct from food and pharmaceutical grades, yet not far behind regarding attention to potential contaminants. The two waters of hydration present set this product apart from its anhydrous or heptahydrate siblings, altering solubility, handling, and the precise molarity needed in finished solutions.

    What Sets This Product Apart

    To folks outside the field, sodium phosphates might all look the same. In practice, small shifts in the ratio of sodium to phosphate and even the count of water molecules lead to very real changes at the user’s bench. Disodium hydrogen phosphate dihydrate dissolves quickly, without tendencies for caking, clumping, or forming inconsistent solutions. Its balanced alkalinity fits the needs of those maintaining buffer systems, especially where precise pH targeting matters. When we get calls from customers facing batch variability, it’s usually because the dihydrate is missing or substituted incorrectly with a different hydrate or the anhydrous form—an easily made mistake that throws off calibration and downstream reactions.

    This particular hydrate, with two waters bound, offers a practical middle ground between the fully anhydrous salt and those with more hydration such as the heptahydrate. That means a solid product with stable storage under ambient conditions, requiring neither the moisture-sensitive precautions of anhydrous types nor the excessive water load of the higher hydrates. For blending dry mixtures where caking could be a problem, or for facilities with humid warehouse air, this stability matters.

    Applications: Lessons Learned Through Experience

    Our manufacturing teams often receive inquiries from water treatment plants, laboratories, and technical formulators—all with slightly different views of what counts as “good” disodium hydrogen phosphate dihydrate. The salt serves as a reliable buffering agent in large and small scale applications. You’ll find it balancing equations in chemical analysis labs, managing pH for industrial rinses, and supporting gentle cleaning formulations. Each end user values traceability, purity, and batch reliability—even those in lower-tier applications.

    In water treatment settings, consistency really becomes the name of the game. Operators require full trust that every bag or drum delivers exactly what’s expected. We take pride in producing for this segment, as our raw materials, filtration systems, and batch checks aim for the tightest tolerances. The dihydrate aids in softening and conditioning, supporting municipal and industrial systems to reach their output standards without unexpected downtime or product rejections.

    Formulation teams—think detergents, cleaning agents and sometimes even food processing aids—utilize disodium hydrogen phosphate dihydrate for its controlled release of alkalinity and phosphate. Here, solubility becomes critical, and the dihydrate’s solubility profile delivers sufficient phosphate ions without overwhelming the solution with excess water.

    Academic, clinical, and industrial labs use this salt in buffer solutions. Unlike monobasic or tribasic phosphates, the dihydrate form balances pH in a broader, more manageable range. While monobasic (NaH2PO4) pushes pH on the acidic side and tribasic (Na3PO4) on the strongly alkaline side, our dihydrate gets adopted specifically for neutral or just-alkaline buffer systems. In my experience, even a slight swap among these can cause experiments to fail or processes to drift out of specification.

    Production Insights: Purity from Raw Materials Up

    Making disodium hydrogen phosphate dihydrate isn’t just about mixing sodium carbonate or sodium hydroxide with phosphoric acid. The devil remains in the details: the grades of input, the water’s purity, and the management of reaction conditions. Phosphates, by nature, have a tendency to form insoluble impurities with traces of calcium or magnesium. Over the years, our quality control team developed a deep-cleaning routine for reaction vessels and adopted filters that catch even sub-micron particulates, helping us deliver a consistently bright, clean product.

    We test each batch for the most likely critical impurities—heavy metals, insoluble iron, and water-insoluble residues that can wreak havoc during buffer preparation or application in sensitive recipes. The dihydrate gets a double-check for its water of hydration, since slight swings in moisture content throw off calculations, especially in laboratory use or when customers work with strict protocols. Our in-line controls and gravimetric checks flag outliers before they hit the bagging stage.

    Consistency is also about logistics. Phosphate products draw moisture if left unsealed too long, and ambient humidity in the plant pushes us toward packing fast and with minimum headspace. We use packaging designs proven to restrict moisture ingress, and our warehouse teams monitor storage rooms for any signs of temperature or humidity swings that could impact shelf life.

    Safety, Handling, and Responsible Manufacturing

    Working with disodium hydrogen phosphate dihydrate along the production line, employees know that responsible handling means a safe workplace. The product has a solid safety profile compared to some more hazardous materials, but dust control, proper ventilation, and the use of basic protective gear remain standard. We invest in dust extraction points at filling stations and reinforce the importance of daily checks on filters and covers. These practices aren't just about meeting compliance; they're rooted in experience and a clear history of long-term operator health.

    Waste management forms another story. Our effluent from phosphate production cycles back through neutralization and settling systems, aiming to minimize phosphate content in any discharge. The spent filters, once loaded, are neutralized and sent for approved disposal—not just for environmental compliance, but because our team lives in the same neighborhoods and wants the same safe water as everyone else.

    Differentiating From Other Phosphate Salts

    Product confusion causes more headaches for our technical support teams than almost anything else. End users sometimes swap among sodium phosphate salts, thinking they’re interchangeable. They aren’t. Disodium hydrogen phosphate dihydrate sits between acid and alkali, delivering moderate alkalinity without steering the solution too strongly away from neutral. Anhydrous Na2HPO4, though apparently similar, behaves differently in mixing and dosage calculations, while the heptahydrate delivers excess water and a lower active content per gram.

    By focusing our process specifically on the dihydrate, we make sure customers asking for predictable buffer behavior, straightforward solubility, and stable physical handling can trust what arrives. It isn’t just a matter of water content—also the crystal structure, bulk density, and powder flowability change across forms. Plant operators and lab techs looking for precise control find the dihydrate least likely to clump or spoil in normal ambient storage.

    We keep detailed records allowing full traceability of all batches, as our clients in pharmaceuticals and diagnostics require disclosure regarding sources and process controls. The audit trail covers each step, from incoming phosphoric acid shipments to final blending. We invest in staff training not only in response to audits, but because understanding the “why” behind each process step reduces errors and increases team ownership.

    Supporting Research and Industry Growth

    Our facility collaborates with universities and industry partners testing new uses and formulations—whether in water softening, fire retardants, ceramics, or specialty chemicals. Disodium hydrogen phosphate dihydrate finds its way into these projects thanks to its versatility and dependably clean background. We’ve seen it used as a buffering agent in microbial growth media, a stabilizer in the manufacture of certain fire-resistant materials, and sometimes even as an additive in specialized fermentation processes.

    Fields like food safety and clinical diagnostics increasingly require impurities testing that pushes limits once considered excessive for industrial supply. Responding to these expectations, our plant invests in modern chromatography and spectrometry tools. We’ve found that our best approach remains not just meeting minimum specs, but consistently exceeding them—delivering a product trusted by both large-scale blenders and small-batch research chemists.

    Solutions for Common Challenges

    Customers sometimes find themselves frustrated by unexpected results this product doesn’t cause directly—often, problems arise by treating hydrates interchangeably, or storing phosphate salts in poorly controlled environments. Our technical support staff regularly helps resolve these pain points. We recommend clear labelling and in-plant segregation of sodium phosphate forms, minimizing the risk of cross-use. For high-humidity facilities, we suggest double-bagging and storing in a dry, cool section, sometimes even alongside desiccant packs in more critical environments.

    Users aiming for exact molar concentrations benefit from gravimetric calculation using the published molecular weight of the dihydrate, not the anhydrous value, since the difference means order-of-magnitude shifts in resulting solution concentrations. Those producing large blended formulations often find our product flows well enough for dosing by augur or gravimetric feeder, reducing bridging events during transfer.

    To further help customers avoid pitfalls, we share our batch certificates routinely and answer questions about hydration variability. For those scaling up pilot lines or launching a new production campaign, our plant chemists consult directly to review phosphate ratios and compounding methodology, a step we take to save both sides trouble down the road.

    Looking Forward: Innovations and Evolving Needs

    Phosphate chemistry continues to adapt in response to changing regulatory standards and sustainability goals. We monitor shifts in permitted discharge levels for phosphate in water systems and scaling controls, knowing these changes influence both the demand for our product and the requirements for purity and traceability. Our R&D group actively researches energy-efficient drying and filtration, so future customers can expect not only consistent quality but also lower embodied energy per kilogram produced.

    Our production line also explores alternative packaging and handling systems, looking toward better recyclability and ease of storage. Collaborating with our freight partners, we aim to reduce physical handling and minimize accidental exposure for all involved. These changes matter to our downstream partners and the operators onsite.

    In summary, decades of hands-on involvement have shown us that disodium hydrogen phosphate dihydrate isn’t just another commodity chemical. Reliable output, strict process controls, and transparent support set our approach apart in the field. We see the compound as a dependable solution—helping facilitate progress in water treatment, technical formulation, laboratory analysis, and a host of areas where precision and purity really matter. From our factory floor to your facility, we build every batch with care, keeping both our experience and your end use in sharp focus.