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Diphenylamine Hydrochloride

    • Product Name Diphenylamine Hydrochloride
    • Alias DPA-HCL
    • Einecs 204-434-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    964787

    Chemical Name Diphenylamine Hydrochloride
    Cas Number 3064-60-6
    Molecular Formula C12H12ClN
    Molecular Weight 205.69 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 163-165°C
    Solubility In Water Soluble
    Synonyms N-Phenylaniline hydrochloride
    Storage Conditions Store in a cool, dry place, tightly closed
    Purity Typically ≥98%
    Odor Characteristic
    Hazard Class Irritant
    Boiling Point Decomposes before boiling

    As an accredited Diphenylamine Hydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Diphenylamine Hydrochloride, 100g, is packaged in a tightly sealed amber glass bottle with a clear label displaying hazard and handling information.
    Shipping Diphenylamine Hydrochloride is shipped in tightly sealed containers to prevent moisture absorption and contamination. It is labeled according to chemical safety regulations, with appropriate hazard warnings. The package is cushioned against shocks and typically transported as a non-hazardous solid under normal shipping conditions. Handle with care and store in a cool, dry place.
    Storage Diphenylamine hydrochloride should be stored in a tightly sealed container in a cool, dry, well-ventilated area, away from incompatible substances such as oxidizing agents and strong bases. Keep it out of direct sunlight and sources of moisture. Ensure proper labeling, and restrict access to trained personnel. Use appropriate secondary containment to prevent spills and contamination of other chemicals.
    Application of Diphenylamine Hydrochloride

    Applications of Diphenylamine Hydrochloride in Industrial Manufacturing

    We specialize in the production of Diphenylamine Hydrochloride, supplying demanding industrial sectors that require consistency in purity, traceability, and process performance. Through years of collaboration with downstream manufacturers, we support select applications that rely on this compound’s specific chemical attributes for formulation stability, reaction control, and product reliability. Below, we present primary real-use scenarios across prominent industries, with detail on compliance, integration, usage, and finished goods.

    1. Pharmaceutical API Intermediate Synthesis

    Diphenylamine Hydrochloride plays a critical role as an intermediate in the synthesis of certain antihistamine and antipyretic active pharmaceutical ingredients. Its value in this application is based on precise reactivity under controlled pH, which is essential for stepwise heterocyclic formation. Integration into the multi-stage synthetic route requires consistent assay values and low inorganic contaminant levels, which respond directly to strict cGMP oversight and batch-to-batch quality verification in regulated facilities producing APIs for regulated markets.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211 (if destined for US market)
    • European Pharmacopoeia (Ph. Eur.) requirements for intermediates
    • ISO 9001:2015 certified supplier traceability

    Typical usage ratio

    • 0.4%–3.0% of total batch mass, adjusted based on the target API’s synthetic route and molar balance requirements. Process chemists determine exact ratios following route optimization and pilot-scale trials.

    Downstream process integration

    • Charged to reaction vessels during early or intermediate condensation and cyclization stages, under nitrogen or controlled atmosphere, often dissolved in aqueous or alcoholic solvents for precise dosing and dispersion.

    Final product types

    • Antihistamine API compounds (e.g., diphenhydramine-class intermediates)
    • Antipyretic and analgesic precursor chemicals

    2. Electroplating Brightener Additives

    Within the metal finishing sector, Diphenylamine Hydrochloride serves as a key functional additive in copper and nickel electroplating solutions, where it enhances brightness and uniformity of metallic deposits. Plating bath formulators depend on the compound’s ability to minimize dendrite formation and refine grain microstructure, which translates directly into improved physical properties and aesthetic appearance on industrial components. This application falls under tight environmental and safety controls, particularly regarding worker exposure and wastewater management.

    Industry compliance standards

    • ISO 12686:2016 (Electroplated coatings—Nickel and nickel alloys—Test methods for deposit)
    • OECD chemical safety assessments
    • REACH (if supplied into the EU/EEA region)
    • RoHS suitability for finished parts used in electrical products

    Typical usage ratio

    • 10–50 mg/L in copper or nickel plating baths. Technicians adjust based on bath size, agitation rates, and the type of metal substrate to achieve optimal surface finish and deposit morphology.

    Downstream process integration

    • Added to formulation tanks as a liquid feed solution or pre-dissolved concentrate; integrated during make-up or bath maintenance cycle; monitored in-process by analytical titration or chromatography for effective dosing throughout plating campaigns.

    Final product types

    • Connectors and contacts for electronics
    • Automotive trim components
    • Decorative and functional household hardware

    3. Rubber Antioxidant Manufacturing

    This compound features in the production of specialty rubber antioxidants, where its secondary amine structure offers stabilization against oxidation under high temperature and UV exposure. Formulators in the tire and industrial rubber sector include it to extend in-service life, particularly for extruded, molded, or calendared parts used in harsh environments. The downstream production relies on proper compounding practice and meets statutory toxicity and migration limits set for rubbers in contact with food or potable water, where relevant.

    Industry compliance standards

    • 21 CFR 177.2600 (Rubber articles intended for repeated use, US FDA, if for food-contact products)
    • EN 2002-1892 (Elastomers—Requirements for non-metallic materials approved for potable water)
    • ASTM D3156 Standard
    • ISO/TS 16949: Automotive rubber supply chain requirements

    Typical usage ratio

    • 0.2%–1.5% by weight relative to total polymer mass, tuned to polymer type (SBR, NBR, NR) and desired performance window; rubber technologists may increase loading in thick-section parts or high-heat applications.

    Downstream process integration

    • Incorporated during masterbatch blending with base elastomers, typically in Banbury or open mill stages, prior to sulfur crosslinking/vulcanization; dispersion quality and temperature profile during mixing are closely monitored in QC protocols.

    Final product types

    • Automotive/industrial tire sidewalls
    • Conveyor and transmission belts for heavy machinery
    • Seals, O-rings, and gasket materials

    4. Stabilizer in Nitrocellulose-Based Propellants

    Our clients in the explosives and propellants industry depend on Diphenylamine Hydrochloride as a stabilizer for nitrocellulose-based formulations, including single- and double-base propellant grains and sheets. The compound’s proven scavenging effect for nitrogen oxides slows the autocatalytic decomposition of nitrocellulose, supporting shelf-life and safe product performance under varied temperature and humidity conditions. Downstream manufacturers operate under national and international civilian and defense product controls and must document each material batch entry by qualified, audited supplier sources.

    Industry compliance standards

    • UN Orange Book: Recommendations on the Transport of Dangerous Goods
    • US MIL-STD-286 (Chemical and physical tests for propellants)
    • EN 13631–3: Requirements for propellants and explosives used in civil blasting
    • Defense Federal Acquisition Regulation Supplement (DFARS) for military contracting

    Typical usage ratio

    • 0.5%–2.0% of finished propellant mass, depending on base nitrocellulose content, intended storage life, and projected thermal cycling conditions throughout transporter or field deployment.

    Downstream process integration

    • Added during the nitration and mixing stage of propellant batch formulation; monitoring is performed via HPLC or TLC post-mixing, prior to extrusion, granulation, or sheet formation and subsequent drying.

    Final product types

    • Small arms cartridges (civilian and defense)
    • Solid propellant rocket grains
    • Industrial detonator fuses

    5. Dye Intermediate for Azo and Triarylmethane Pigment Manufacture

    Diphenylamine Hydrochloride serves as a raw material for diazotization, coupling, and subsequent ring closure processes in the creation of certain azo and triarylmethane dyes and pigments. The compound introduces colorfast aromatic nuclei and assists manufacturers in tuning color intensity and hue stability in coatings, plastics, and printing ink systems. Compliance with global dye safety and migration standards remains a priority for manufacturers targeting automotive, textile, or food packaging applications.

    Industry compliance standards

    • REACH Annex XVII (Restrictions on certain hazardous substances in dyes/pigments)
    • OEKO-TEX Standard 100 if used in textile dyeing
    • EN 71-3 for pigments in toys and children’s articles
    • ISO 1248: Pigments for paints

    Typical usage ratio

    • Ranges from 0.3 molar equiv. to 1.1 equiv. per diazotization batch, calculated against total amine reactants; dye chemists optimize ratios according to target chromophore and solubility requirements in the specific application (aqueous, solvent, or oil systems).

    Downstream process integration

    • Admitted to batch reactors or continuous stirred-tank reactors for diazotization or coupling reactions; conversion and yield depend on stoichiometry control and temperature/acidic pH profile throughout batch operation.

    Final product types

    • Azo and triphenylmethane pigments for plastics compounding
    • Printing and lithographic inks
    • Industrial and decorative paints and coatings
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    Certification & Compliance
    More Introduction

    Diphenylamine Hydrochloride: A Closer Look Through a Manufacturer’s Lens

    Understanding Our Commitment to Chemical Quality

    For years of producing Diphenylamine Hydrochloride, our team has seen the industry’s standards evolve and with each batch, we meet new demands from research labs and industrial partners. Quality always comes down to details that matter in the daily running of chemical processes. We constantly source our raw diphenylamine from trusted suppliers and control every step of the conversion to its hydrochloride salt. In a manufacturing space, minor inconsistencies can lead to unexpected issues in the lab, which is why stringent testing has become part of our routine, not just a checkpoint.

    The Model We Produce and Why It Matters

    Our model of Diphenylamine Hydrochloride reflects what leading chemists and technicians actually use. The finished product has a tight particle size distribution—an outcome of carefully adjusted crystallization and drying—minimizing dust and clumping. Chemists ask about this because any caking means trouble during weighing and mixing. Our own staff also finds smoother powder easier to handle, limiting product loss and cross-contamination, which nobody wants in a tightly regulated workplace.

    From the earliest development, our technical staff selects synthesis conditions that balance purity against operational practicality. Chemical purity consistently reaches above 99%, a number that keeps our product competitive for both analytical labs and industrial users. These results are verified by internal HPLC and GC-MS, so end users receive documentation traced back to batches, not generic data sheets. Purity should not come at the cost of unpredictable performance, so we test every drum for actual usability.

    Specifications Rooted in Real Workflows

    Over years of feedback from industry, we’ve fine-tuned the handling properties of Diphenylamine Hydrochloride. Each lot undergoes moisture and residue analysis that can screen for trace impurities. We check not only chloride content, but also the amount of residual free base, to ensure predictable reactivity. Organic syntheses often fail from overlooked contaminants, so our standard includes regular checks for non-volatile residues and a report on any trace metals.

    We pack Diphenylamine Hydrochloride in double-sealed, inert-lined containers, built not just for storage shelf life, but for repeated opening at the point of use. Unlike some standard drums, our packaging protects against moisture pick-up as soon as the seal is broken. In practical workspaces, powders get exposed and re-sealed dozens of times. We see fewer customer complaints because our chemical keeps its properties over repeated use cycles, and lab staff appreciates not having to scrape or break up lumps.

    Physically, the off-white appearance means the absence of unwanted intermediates that could interfere with colorimetric tests, and the crystalline nature translates to more consistent dosing in setups that rely on low-milligram accuracy.

    The Role of Diphenylamine Hydrochloride in Industry

    Chemicals find purpose at the hands of those who use them—and Diphenylamine Hydrochloride’s strength lies in its performance under pressure. In the chemical laboratory, it serves as a well-characterized reagent for detection of oxidants and as a key intermediate in dye manufacturing. Some customers employ it for its selective reactivity in pharmaceutical research. Years ago, production was limited by basic purity standards, but users began to demand higher performance for their own product development. Our team opened direct lines for customer feedback and implemented process improvements in response, giving end users a say in what they actually receive.

    Unlike other diphenylamine derivatives, the hydrochloride salt offers better solubility in aqueous systems, avoiding the floating or sticking behavior that can slow down or complicate experimental setups. Our staff has worked side by side with customer labs to troubleshoot solubility bottlenecks, finding that the fine crystalline form speeds up dissolution without excessive foaming or loss of material. These small gains matter in high-throughput labs where every step saved counts towards production goals.

    What Sets Diphenylamine Hydrochloride Apart

    Within the broad landscape of amine-based reagents, Diphenylamine Hydrochloride lives in a crossroads of stability and reactivity. Its shelf life, when kept dry and sealed, outpaces many closely related products, particularly the free base, which absorbs moisture and can degrade on storage. The hydrochloride salt carries more predictable handling traits, which takes pressure off both the purchasing team and the technical bench chemist. We continually find that our customers return to this product because broken batches are a hassle—nobody wants to clean up piles of clumped powder or worry about uncertain potency.

    Unlike common bulk chemicals, Diphenylamine Hydrochloride responds sensitively to environmental handling. Three years ago, a batch exposed to excessive humidity during shipping prompted us to upgrade our container linings. Without reliable protection, reactive salts like this can pull water from the air, leading to bloated containers or even messes on the warehouse floor. We track environmental impact and stress-test both chemical and packaging, using field data rather than lab-only conditions to guide upgrades.

    Addressing Common Questions from Chemists and Procurement Teams

    Chemists tend to worry about batch-to-batch variability. Our in-house logs and test results, gathered over decades, reduce guesswork and save labs from running extra blank tests. Real documentation sits in our records and ships with every order, letting customers check performance and trace issues directly. We avoid delays in scale-up because end users can request historical purity and impurity data from us directly, rather than sift through intermediaries.

    Concerns about supply gaps matter in fast-paced industries. We hold buffer stocks and synchronize production runs to those of key partner industries, so downtime or shortages at the manufacturer’s level do not leave customers scrambling to source from unpredictable brokers. Having worked through several global shipping disruptions, our team prioritizes transparent communication and realistic timelines, based on what’s on our floor—never just speculative promises. Customers have told us how critical this is for their planning.

    Learning from Different Users Over Time

    The journey of Diphenylamine Hydrochloride in our plant has been shaped by feedback from analytical chemists and bulk buyers alike. Academic research groups appreciate the ease of weighing and the reproducibility across orders, while large-scale buyers demand robust packaging and documentation. Regulatory audits—though time-consuming—keep us focused on updated best practices, not just legacy targets. It’s this continuing loop of production, use, feedback, and improvement that keeps our operation aligned with what really works in the field.

    Every release starts with a cross-check between documentation and physical sample, because it is routine to spot subtle appearance changes before they show up in the data. If a product behaves differently—a slight shift in melting point, crystal habit, or odor—operations staff investigate before release, not after complaints. Minor early interventions have saved us and our partners countless hours that would otherwise go into post-delivery troubleshooting.

    Comparing Diphenylamine Hydrochloride with Other Reagents

    There are many choices for stabilization and detection in laboratory and industrial applications. Some producers have turned to methylated or halogenated analogues, but these often come with different solubility traits and can introduce side responses in analytical tests. Diphenylamine Hydrochloride offers a middle ground: greater stability than the parent amine, manageable safety characteristics, and a strong record of reliable analytical response. In dye and pharmaceutical intermediates, certain substituted forms have experienced supply volatility and suffered from more complicated disposal requirements.

    In our operation, product selection is more than price per kilogram—it’s a balance of usability and risk. Our batches of Diphenylamine Hydrochloride meet documentation requirements for modern regulated workplaces and can be disposed of more predictably than many specialty organic derivatives. Companies that try to replace it with a lower-cost alternative often return after running into consistency issues or downstream compatibility problems. To keep production lines running smoothly, many have opted for the predictable performance and simpler logistics our product provides.

    Challenges and Ongoing Solutions in Manufacturing

    Producing Diphenylamine Hydrochloride involves more than standard chemical synthesis. Raw input selection, monitoring reaction endpoints, and keeping a tight rein on drying conditions all affect the final product. Working with older equipment in the early days, our team saw a spike in variability that never appeared on paper but showed up as customer dissatisfaction. Modern digital controls have reduced these hiccups, cutting back on batch rework and minimizing waste. Each investment in upgraded process control stems from conversations and data gathered after every feedback cycle.

    Environmental responsibility now plays a much bigger role in chemical manufacturing. From water discharge monitoring to reduced emissions during synthesis, we’ve changed many old habits without compromising product quality. Regulatory changes have required faster adaptation, but years of close recordkeeping and real-world process evaluation let us navigate new wastewater and chemical storage rules without supply issues. Our records show not just compliance, but a trend towards fewer product complaints tied to contamination.

    Product stewardship does not end with the drum leaving our doors. We provide disposal guidance based on real handling conditions in customer facilities, leaning on documented experience rather than broad advice. Regular talks with user groups keep us up to date on safe disposal procedures in different legal environments. This feedback loop strengthens not only product safety, but also customer trust.

    What We’ve Learned Along the Way

    Throughout our years of supplying Diphenylamine Hydrochloride, lessons come from more than internal quality checks or batch records. People along the chain—production, warehouse, shipping, and customer—spot practical improvement points that statistics might not show. Not one complaint about powder flow in cold climates or slight discoloration during long shipping trips goes ignored. Practical fixes—like reinforced seals and in-line color checks—show up in better product for every end user.

    Mismatches between customer expectations and industry reality shape future production. Product batches must match what is actually needed in hands-on applications, not just meet a minimum spec. If a customer’s analytical method relies on extremely low background contamination, we cross-check our production streams and adjust accordingly. In one case, adding a filtration step eliminated nuisance particles that, while technically within spec, impaired automated dosing units in high-volume labs.

    Our team values collaboration more than arm’s-length transactions. By opening facilities for customer audits and incorporating industry suggestions, we tailor not just the product, but the way it reaches people who use it every day. This has led to new approaches in batch labeling, streamlined documentation, and even alterations in packaging for easier recycling.

    Supporting the Next Steps for Our Partners

    The needs of chemical users keep evolving. Increasing demand for safe, reliable, and traceable materials has pushed us to invest in ongoing improvement. Customers want to avoid regulatory surprises, spot supply risks early, and depend on the manufacturer’s willingness to provide honest answers. We understand the impact of late shipments and changing quality standards on industries that cannot wait for resupply. By focusing on transparent, honest communication, our support extends beyond simply supplying chemical drums.

    During periods of global supply uncertainty, our ability to forecast raw material trends and manage strategic stocks makes a difference for long-term partners. We lean on historical usage patterns, supplier reliability records, and ongoing technical dialogues with our customers. This foundation, grounded in years of experience, allows us to offer more than just a list of available models or off-the-shelf solutions.

    Looking to the Future of Diphenylamine Hydrochloride

    Technological changes, regulatory shifts, and customer-driven innovation all keep shaping the profile of Diphenylamine Hydrochloride in the marketplace. Our journey has moved from basic bulk processing to high-purity, traceable, and more environmentally conscious production. In the hands of researchers and manufacturers, every improvement we make shows up as smoother lab operations, faster process development, and reduced downtime.

    We believe that the best way a manufacturer can serve the industry is to remain open to real feedback and keep investing in both people and processes. With every batch of Diphenylamine Hydrochloride that leaves our facility, we carry forward the lessons and values built over years of hands-on work. This cycle of improvement never truly ends because every new application, regulation, or user requirement challenges us to find better solutions for the people relying on our chemistry.