Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Dimethyl Itaconate

    • Product Name Dimethyl Itaconate
    • Alias Itaconic acid dimethyl ester
    • Einecs 202-611-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    288344

    Cas Number 617-52-7
    Molecular Formula C9H12O4
    Molecular Weight 184.19 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 140-142°C at 13 mmHg
    Density 1.111 g/cm3 at 20°C
    Melting Point -50°C
    Solubility In Water Insoluble
    Flash Point 120°C
    Refractive Index 1.443 at 20°C

    As an accredited Dimethyl Itaconate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Dimethyl Itaconate, 500g, is packaged in a sealed amber glass bottle with a secure screw cap and chemical hazard labeling.
    Shipping Dimethyl Itaconate is shipped in tightly sealed containers, typically made of glass, plastic, or metal to prevent moisture and contamination. It should be stored and transported in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances. Follow all local, national, and international transport regulations.
    Storage Dimethyl Itaconate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from direct sunlight, moisture, and sources of ignition. Avoid contact with strong oxidizing agents. Store at room temperature and keep away from heat, open flames, and incompatible materials. Ensure proper labeling and follow all relevant safety and regulatory guidelines for chemical storage.
    Application of Dimethyl Itaconate

    Applications of Dimethyl Itaconate in Industrial Manufacturing

    Dimethyl Itaconate is a key specialty monomer applied in several industrial sectors where controlled polymerization and specific chemical reactivity are required. As a direct manufacturer, we serve downstream users in multiple segments, enabling precise formulation adjustments, regulatory compliance, and process efficiency for each targeted end use.

    1. Acrylic and Methacrylic Copolymer Resins

    Coating, adhesive, and specialty emulsion producers use Dimethyl Itaconate as a co-monomer to improve flexibility, adhesion, and hydrolysis resistance in acrylic and methacrylic based resins. Its bifunctional structure allows integration into latex systems for paints and pressure-sensitive adhesives. Downstream users rely on accurate dosing to control molecular weight and performance properties that meet high-demand application criteria in automotive, industrial, and construction coatings.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System for resin manufacturing
    • REACH Registration, Evaluation, Authorization and Restriction of Chemicals
    • ASTM D6083 for acrylic roof coating materials
    • Directive 2004/42/EC on VOC content in paints and varnishes

    Typical usage ratio

    • 1–7% by weight of co-monomer loading in acrylic-based systems, adjusted according to adhesive/coating performance targets and polymerization kinetics

    Downstream process integration

    • Introduced into pre-polymerization charge
    • Controlled addition during emulsion or solution polymerization step
    • Adjusted feed alongside primary acrylate or methacrylate monomers
    • Monitored via conversion and copolymer composition analysis

    Final product types

    • Acrylic emulsion polymers for architectural coatings
    • Waterborne and solvent-based industrial primers
    • Pressure-sensitive adhesive tapes and films
    • Flexible sealant compounds

    2. Biodegradable Polymer Synthesis

    Dimethyl Itaconate features widely in the development of biodegradable polymers, particularly poly(itaconate) or itaconate-based copolymers. Packaging, agricultural, and medical materials manufacturers use it to meet sustainability and compostability objectives. Its functional groups support tailored degradation rates and mechanical characteristics for specific downstream conversion processes, balancing environmental compliance with functional product criteria.

    Industry compliance standards

    • EN 13432:2000 for compostable packaging
    • ISO 14855 for aerobic biodegradation of plastics
    • FDA CFR Title 21 for food-contact polymers
    • EU Regulation No 10/2011 on food contact plastic materials

    Typical usage ratio

    • Ranging 10–40% by weight in copolymer composition—noted higher ratios for flexible films, lower for rigid applications, with specific ratio determined by degradation profile and mechanical performance

    Downstream process integration

    • Fed to ring-opening polymerization or step-growth copolymerization reactors
    • Blended as a reactive monomer in melt extrusion with other biodegradable building blocks such as PLA or PBAT
    • Quality controls on conversion, residual monomer, and migration testing
    • In-line monitoring for molecular weight and incorporation ratio

    Final product types

    • Compostable agricultural mulching films
    • Biodegradable packaging foams and trays
    • Food wrap and single-use cutlery
    • Degradable controlled-release agricultural substrates

    3. Pharmaceutical Intermediate Synthesis

    API and intermediate producers source Dimethyl Itaconate as a C5 synthon in heterocyclization, alkylation, and ester exchange reactions. It serves in multi-step routes to antibacterial, antifungal, and antimalarial actives. Stringent reaction controls and regulatory traceability form a core part of this segment, especially when synthetic routes must comply with multi-compendia and high-purity specifications for injectable and oral drugs.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • United States Pharmacopeia (USP) monographs for excipient reactivity
    • European Pharmacopoeia (Ph. Eur.) 11.0
    • 21 CFR Part 211 for finished pharmaceuticals

    Typical usage ratio

    • Stoichiometric, typically 1.0–1.5 molar equivalents relative to nucleophile or reactant in intermediate synthesis, depending on downstream conversion yield requirements

    Downstream process integration

    • Charged as first- or second-step substrate in chemical synthesis routes
    • Subjected to selective hydrogenation, alkylation, or condensation under controlled temperature and pressure
    • Purity and residual solvent checks per GMP protocols
    • Batch-level documentation for traceability and regulatory submission

    Final product types

    • Synthetic itaconate derivatives for antibiotic formulas
    • Intermediates for antifungal drug actives
    • Precursors to chiral building blocks used in advanced pharmaceutical development
    • API candidates for anti-inflammatory products

    4. UV-Curable Formulation Additive

    Producers of UV-cured coatings and inks use Dimethyl Itaconate as a reactive diluent to modify viscosity, cure speed, and final film properties. Its double bond moiety allows efficient copolymerization under light-initiated processes, improving solvent resistance and flexibility in the cured product. Adjusting additive levels supports formulation of low-VOC, energy-efficient systems for graphic arts, electronics, and packaging segments.

    Industry compliance standards

    • EuPIA Guideline for printing inks in food packaging
    • ISO 13655 for print evaluation
    • RoHS 2011/65/EU for electronics coatings
    • SGS migration and residual monomer testing for food-contact coatings

    Typical usage ratio

    • 0.5–5% by wt. in UV-curable formulation, calibrated to match target reactivity, surface tension, and end-use migration limits

    Downstream process integration

    • Introduced during pre-mix blending of resin, photoinitiator, and additional monomers/oligomers
    • Monitored via real-time viscosity adjustment and wetting tests
    • Assessed via final film properties post-cure including adhesion and solvent rub
    • Continuous inline quality check for migration and low residuals

    Final product types

    • UV-flexographic and offset printing inks
    • Electronics circuit board conformal coatings
    • Low-VOC varnishes for food packaging
    • Photocurable adhesives for industrial assembly

    5. Plasticizer and Modifier for Thermoplastic Polyesters

    Dimethyl Itaconate acts as a non-phthalate plasticizer and reactive modifier in the manufacture of thermoplastic polyesters such as PET and PBT. By integrating via co-polycondensation, it enhances thermal stability, impact resistance, and clarity in final resin pellets. End users in packaging, electrical components, and specialty films rely on confirmed ratios and exchange purity to control downstream processability and regulatory acceptance, ensuring physical properties and safety compliance are met without compromising throughput.

    Industry compliance standards

    • FDA 21 CFR §177.1630 for polyesters in food contact
    • UL 746B for polymeric materials in electrical equipment
    • EN 1888 for chemical resistance in consumer goods
    • ISO 22000 for food safety management if used in packaging

    Typical usage ratio

    • 2–15 mol% as a comonomer in melt polycondensation, with higher values for flexible films and lower for rigid applications

    Downstream process integration

    • Fed as a monomer into polycondensation reactor with main acid/glycol feedstocks
    • Integrated prior to final molecular weight build-up/finishing stages
    • Requires tight downstream control of esterification side reactions
    • Inline monitoring ensures batch-to-batch consistency for regulatory audits

    Final product types

    • Food and beverage containers with enhanced clarity
    • Flexible electrical insulation films
    • Molded connectors and automotive components
    • Blister packaging and medical film stock
    Free Quote

    Competitive Dimethyl Itaconate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Dimethyl Itaconate: From Raw Material to Reliability

    Introducing Dimethyl Itaconate From the Perspective of a Manufacturer

    In the world of fine chemicals, every product tells a story about its origins and real-world value. Dimethyl Itaconate (CAS No. 617-52-7) stands out in our line-up not because it's rare or exotic, but because of what we see it doing every day in the hands of our customers. The structure itself—methyl groups flanking the itaconic core—does more than satisfy a chemist's curiosity. This molecular arrangement delivers clear functionality and flexibility for downstream applications. We produce our Dimethyl Itaconate with strict attention to material control, keeping impurities in check and giving customers a repeatable experience from drum to drum. What matters most to us is seeing the product move seamlessly from our tanks to your reactor, letting you focus on your chemistry, not on troubleshooting raw materials.

    Technical Consistency—Our View at the Production Line

    Quality doesn’t happen by decree. At our plant, every batch of Dimethyl Itaconate undergoes GC analysis, NMR checks, and moisture assessment. We produce material with purity at 99% or above, and we maintain tight boundaries on water content to avoid issues in sensitive polyester or resin synthesis. These are not arbitrary numbers—they come from years of feedback and process adjustment, especially as customers adopt new catalytic systems more vulnerable to byproducts. By talking regularly with R&D teams and operators, we learn where a trace of auraldehyde or methanol can throw off an entire batch of polymer. We act on this—and that’s why our material passes without headaches, even under more demanding specifications.

    Models, Grades, and Our Production Flexibility

    Some applications call for Dimethyl Itaconate as a base ester for unsaturated polyester resins, where a slight yellow tint doesn’t impact the final function. Others, such as pharmaceutical intermediate synthesis, require colorless, low-odor, high-purity lots. We run two main grades—standard industrial and high-purity—and we’re ready to customize production when long-term partners request tighter tolerances, improved filtrates, or specialty packaging. We’ve designed our plant to handle modular purification steps and can switch feedstock quality quickly. This agility owes nothing to buzzwords like ‘bespoke manufacturing’—we do it because we talk to real users, and most of the time, a single model does not satisfy the diverse chemical market. Pharmachemists usually ask for lower residual acid, while resin makers push for higher throughput at standard spec. We balance both realities by managing our own process from feedstock up, rather than relying on others’ intermediates.

    Learning From End-User Application Demands

    Every kilogram of Dimethyl Itaconate leaving our site finds a distinct purpose. Resin formulators blend it with styrene for sheet molding compounds or gel coats. Polymer scientists leverage its double bond to crosslink with acrylates for specialty plastics. In the agrochemical world, derivatization of the itaconate structure helps create building blocks for new chemistries. Researchers reach out with non-traditional uses—solvent systems, reactive diluents, even controlled-release platforms. Over time, we saw that issues often arise not from the fundamental chemistry, but from variability in the feedstock—high moisture, inconsistent color, out-of-spec acidity—throwing off downstream results. By controlling our input stream, stripping water, and ensuring minimal residual acidity, we’ve helped customers cut troubleshooting time from days to hours.

    How Dimethyl Itaconate Differs From Other Itaconates and C4/C5 Esters

    Many buyers come in with basic knowledge of itaconic acid esters and wonder: Why pick dimethyl over mono- or diethyl variants, or even over more common acrylate monomers? Experience says it’s in the real behavior. Dimethyl Itaconate introduces a smaller, lighter methyl group versus ethyl, which shifts solubility, boiling point, and reactivity. The methyl ester leaves less steric hindrance during polymerization, leading to denser, crosslinked networks when used in polyester resins. This difference matters most to formulators chasing specific thermal or mechanical properties. Compared to diethyl itaconate, the dimethyl ester also brings lower odor profiles and reduced volatility, making process control easier in large batch or continuous operations.

    On practical grounds, acrylic and methacrylic monomers dominate many of the same polymer markets. Dimethyl Itaconate, though less common, offers greener chemistry—originating from itaconic acid, which can be fermented from renewable sources. This renewable angle appeals especially to customers targeting bio-based resin certifications, and we put effort into documenting our supply chain and process sustainability. The other factor at play relates to regulatory nuance. In several cases, switching from acrylate monomers to Dimethyl Itaconate helps avoid stricter labeling or permits. These specifics change by country, but the broader benefit remains—some customers find easier compliance and less risk by using our product.

    Production: Beyond the Brochure

    We don’t see ourselves as mere suppliers. Years of making Dimethyl Itaconate at scale exposed us to process hiccups that most technical sheets gloss over. Take batch heating—if not managed carefully, localized hot spots can darken the ester, producing off-colors that customers reject. We solve it by carefully controlling jacket temperatures and monitoring color values inline. Water content, a persistent trouble point, sneaks in both from atmospheric exposure and some lower-grade feedstocks. Instead of relying solely on vacuum drying at the end, we optimize our reaction setup to minimize water carryover from the start, slashing process bottlenecks and giving a longer shelf life. Packaging too, plays a part. Some customers benefit from small-volume drums for lab work, while others move to IBC totes or bulk isotanks. We upgraded our filling lines to offer both, making sure to inert the headspace with nitrogen for longer shelf stability.

    Direct Experience Serves Best in Troubleshooting

    Sometimes customers call with feedback about a formulation shift or unexpected gel formation. Instead of firing off a generic response, we match their production data with our batch records and even pull retain samples for reanalysis. Experience taught us that most root causes tie back to minor impurities—either methanol residues or tiny amounts of itaconic acid sneaking through. We adjust both purification steps and distillation schedules to reduce these risks batch by batch, not only for that customer but for the market as a whole. The value isn’t in what the brochure promises, but in what the next order delivers—the reliability to keep production ticking without troubleshooting over raw materials.

    Dimethyl Itaconate in Performance Polymers—What Matters Most

    Resin and plastic manufacturers account for most of our business, and direct dialogue shapes our understanding of what they need. They care less about origin stories and more about flow, cure rate, and finished product aesthetics. Dimethyl Itaconate grants high reactivity without the aggressive odor of lower-chain acrylates. Its compatibility with various monomers opens doors for formulators seeking balance between rigidity and impact resistance. For those aiming to push glass transition temperature or create new crosslinked networks, the methyl groups play a subtle role. Unlike its ethyl or longer-chain cousins, our dimethyl variant slashes molecular weight, affecting not just curing times, but the ease with which catalysts work. Failures often trace back to excess acid values or side reactions from trace aldehydes, so we clamp down on these contaminants upstream. Our technical service team works in tandem with customer R&D to test new curing protocols and respond quickly if outcomes shift. This partnership, rather than box-ticking, steers how we upgrade our production and quality assurance.

    Comparing Dimethyl Itaconate to Other Building Blocks

    Dimethyl Itaconate gets measured against acrylates and methacrylates on price and performance. Raw material volatility aside, the route from sugar fermentation to itaconic acid, and then esterification to the final product, brings different environmental questions and sourcing variability. We source sugar-based feedstocks and monitor their performance from one harvest season to the next, adjusting our own controls. In the case of pure price, big acrylates often win in cost per ton, but for customers aiming for specific regulatory targets or seeking renewable content, the equation looks different. Our direct control lets us chase consistency of supply, color, and functionality, without constantly changing formulations to suit shifting product specs.

    Supporting Sustainable Chemistry

    For the growing number of customers focused on sustainability, Dimethyl Itaconate makes sense, and we enable this by documenting traceability back to our sourcing. Fermentation-based itaconic acid places us closer to the goals that end-product certifications require. We know these audits well—our quality and traceability teams walk through the supply chain details, refining documentation so customers can secure approvals or ecolabels for their finished goods. Steps like water and energy usage also weigh into our own process improvements, as sustainability becomes less of a buzzword and more of a universal customer requirement. We continually invest in reducing solvent use, recycling process water, and capturing off-gas byproducts. Our own customers provide feedback that fuels real change.

    Packing and Logistics: Experience on the Ground

    Shipping bulk chemicals brings complications most users rarely consider. Dimethyl Itaconate, though stable by itself, still needs the right packaging and logistics planning to avoid contamination or loss of quality. We store material in lined drums or stainless IBCs, sparged with nitrogen to hold off oxidation and water pickup. Engineered plugs and leak protection drop the odds of drum failures during shipping. Our logistics crew grew up in the business—knowing when to hold a batch after a heat wave, or how to stagger shipments for seasonal inventory spikes. We don’t leave shipping to chance, as even the best batch loses its value if degraded by transit mistakes. This mindset keeps returned goods to a minimum and lets users focus their energy where it counts.

    The Human Side of Quality

    No automated system replaces the watchful eyes of our crew. We select operators based on attention to detail and product familiarity, knowing that a step missed in cleaning or sampling can echo through thousands of kilos of finished material. That commitment stretches to how we track every outgoing drum or tote—giving traceability from production date right down to shift operator initials. Frequent process audits and customer-driven improvement plans help us stay nimble. Real world experience—fixing clogged lines, riding out a storm that delays a bulk tank, fielding 3 a.m. calls about viscosity swings—teaches more than any specification sheet could.

    Open Dialogue Drives Progress

    Dimethyl Itaconate adapts with the industries that use it. Our ears stay open to formulators, engineers, and purchasing teams who push us to improve. Regular technical calls, annual audits, and joint research shape not just material grades but how and where we innovate next. We document this user feedback with as much care as we monitor GC traces and moisture levels—knowing the hard truths from the factory floor pave the way for lasting progress. Product improvement doesn’t end with box-ticked tests; it moves through feedback loops into our tanks, evaporators, and reactors.

    Supporting Next-Generation Applications

    Dimethyl Itaconate attracts newer thinkers in the specialty chemicals world. Startups developing smart polymers look at it as a platform for reactive sites or biodegradable chains. Biocompatibility and alternative reaction chemistries—these themes now shape R&D dialogues. We field requests for pilot-scale lots with unusual purity demands or custom functional tests, adapting our lines to help bridge lab proof-of-concept to commercial scale. By pairing technical know-how with flexibility in batch sizing, we support these innovators at every stage, collecting data and learning where old paradigms break.

    Navigating Regulatory Demands

    Rules around chemical handling and registration shape both our day-to-day work and customer documentation. Dimethyl Itaconate avoids some of the heavier regulatory red tape found with acrylates in certain jurisdictions, though regional rules evolve quickly. We keep a direct line to compliance specialists and respond promptly to customer questions about product stewardship, labeling, and supporting documents. Decades in the sector taught us to prepare in advance, ensuring shipments carry full sets of regulatory documentation and best practices so that audits and inspections move quickly. We refuse to take shortcuts on compliance because experience points to the cost, both monetary and reputational, of a regulatory misstep.

    Direct Support: Why Real Manufacturer Connection Matters

    The strength of our product lies not just in a molecule, but in the human link that stands behind it. We encourage customers to call us directly when an issue arises or an adjustment is needed. Troubleshooting is far more effective when you reach the actual production team rather than bouncing between intermediaries. Customers tell us this saves weeks in new project ramp-up or problem resolution—because we know the process, the checks, and the history behind every order. Our open-door approach keeps technical problems small before they balloon, fostering transparency and trust from one batch to the next.

    Charting a Future With Dimethyl Itaconate

    Our experience as a dedicated Dimethyl Itaconate manufacturer shapes everything from batch integrity to big-picture market shifts. From drum one to the ten-thousandth, every tonne reflects our drive for reliability, transparency, and partnership. Whether your needs call for high-purity lots in pharma, robust flow for unsaturated polyesters, or traceable supply chains for sustainable chemistry, we build each solution upon what we learn with our customers. This day-to-day cooperation delivers more than a spec-driven product—it backs up every shipment with the quiet confidence that comes only from years on the production floor, solving real problems with real experience.