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Diethyl Ethyl(1-Methylbutyl)Malonate

    • Product Name Diethyl Ethyl(1-Methylbutyl)Malonate
    • Alias DEEMBM
    • Einecs 241-166-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    109162

    Chemicalname Diethyl Ethyl(1-Methylbutyl)Malonate
    Molecularformula C14H26O4
    Molecularweight 258.36 g/mol
    Casnumber 66997-55-9
    Appearance Colorless to pale yellow liquid
    Boilingpoint Approx. 126-128°C at 13 mmHg
    Density 0.965 g/cm³ at 20°C
    Refractiveindex 1.423 - 1.427
    Solubility Insoluble in water, soluble in alcohols and ethers
    Purity Typically >98%
    Storagetemperature Store at 2-8°C
    Smiles CCOC(=O)C(C(=O)OCC)(C)CCC

    As an accredited Diethyl Ethyl(1-Methylbutyl)Malonate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 mL amber glass bottle with secure screw cap, labeled "Diethyl Ethyl(1-Methylbutyl)Malonate", includes hazard warnings and batch details.
    Shipping Diethyl Ethyl(1-Methylbutyl)Malonate should be shipped in tightly sealed containers under inert atmosphere to prevent moisture and contamination. Store and transport at ambient temperature, away from heat, flames, and oxidizers. Ensure compliance with relevant chemical shipping regulations, using proper labeling and documentation. Handle with appropriate personal protective equipment as per MSDS guidelines.
    Storage Diethyl Ethyl(1-Methylbutyl)Malonate should be stored in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible substances such as strong oxidizers. Keep the container tightly closed when not in use to prevent moisture absorption and contamination. Store in a chemical-resistant, properly labeled container, and follow all applicable safety and regulatory guidelines for handling organic esters.
    Application of Diethyl Ethyl(1-Methylbutyl)Malonate

    Applications of Diethyl Ethyl(1-Methylbutyl)Malonate in Industrial Manufacturing

    As an integrated chemical raw material producer, we supply Diethyl Ethyl(1-Methylbutyl)Malonate to specialized manufacturers across select industries. Rigorous quality control, traceability, and support for compliance underpin use throughout sensitive synthesis routes where consistent intermediate performance is central to downstream efficiency.

    1. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) Synthesis

    Diethyl Ethyl(1-Methylbutyl)Malonate functions as a chain elongation intermediate in the vapor-phase alkylation step during the production of certain advanced pharmaceutical intermediates, particularly for APIs in beta-lactam and cephalosporin product lines. Its molecular structure enables selective introduction of branched carbon units, crucial in the fine-tuning of pharmacologically active moieties. Our technical service team supports process chemists in mapping precise dosing to optimize step yield and minimize impurity formation compliant with global medicinal standards.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 211: U.S. cGMP for Finished Pharmaceuticals
    • EDQM CEP-certified process routes
    • Chinese Pharmacopoeia (ChP) and European Pharmacopoeia (Ph. Eur) controls for API starting materials

    Typical usage ratio

    • 5–15% molar ratio versus target core structure, with adjustments based on nucleophile activity and scale-up batch consistency

    Downstream process integration

    • Introduced at the early condensation stage; fully consumed during subsequent hydrolysis and cyclization to generate pharmacologically relevant beta-lactam scaffolds

    Final product types

    • Oral and injectable cephalosporin antibiotics
    • Specialty API compounds requiring branched dialkyl side-chains
    • Intermediates for penem/penam analogs

    2. Agrochemical Synthesis for Selective Herbicides

    The compound enables formation of branched carboxylate groups critical in post-emergent herbicide active ingredients. Downstream producers value the defined reactivity window in nucleophilic substitution steps, which facilitates environmental byproduct minimization during large-scale synthesis. Recommendations for integration into standard plant protection chemical routes comply with both international and national regulatory frameworks.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for Agrochemical Production
    • FAO/WHO Codex Alimentarius for pesticide ingredient purity
    • REACH Annexes VII–X: Registration for chemical intermediates
    • Chinese ICAMA license requirements for technical herbicide intermediates

    Typical usage ratio

    • 7–18% w/w within synthesis step based on batch volume, adjusted to limit residual esterification byproducts according to customer’s impurity threshold

    Downstream process integration

    • Charged in the nucleophilic substitution stage after activation of the core pyridine or triazine ring; in-situ conversion under controlled alkali conditions to derive the herbicidal carboxylate structure

    Final product types

    • Selective post-emergence herbicide actives for cereal and broadleaf crop protection
    • Formulated technical herbicide concentrates
    • Agrochemical precursor intermediates

    3. Synthesis of UV-Absorber Intermediates for Polymer Additives

    Manufacturers use Diethyl Ethyl(1-Methylbutyl)Malonate as a specific branching agent in the alkyl-malonate step to impart photostability in downstream benzotriazole UV-absorber compounds, especially for engineering thermoplastics. Its molecular profile offers predictably low volatility during solvent-free transesterification, allowing high recovery rates without thermal decomposition.

    Industry compliance standards

    • DIN EN 12877-1: Testing of Colourants and Additives for Plastics
    • RoHS Directive 2011/65/EU for restriction of hazardous substances in electronic plastics
    • ISO 9001:2015 in plastics and polymer processing
    • REACH Regulation (EC) No 1907/2006 concerning polymer auxiliaries

    Typical usage ratio

    • 10–16% w/w in precursor charge, with ratio calibrated by polymer matrix compatibility and targeted UV absorbance index for final additive

    Downstream process integration

    • Dosed at the transesterification reaction stage; product then processed to isolate high-purity photostabilizer intermediates for subsequent coupling with benzotriazole cores

    Final product types

    • UV-stabilizer masterbatches for polypropylene and polyethylene
    • Benzotriazole-based light stabilizers for engineering plastics
    • Polymer additive concentrates for automotive and electronics sectors

    4. Flavor and Fragrance Intermediate Synthesis for Fine Chemicals

    This malonate ester serves as a backbone intermediate for certain fruity and floral esters, especially those incorporated in specialty fragrance oils and complex food-grade flavorings. Controlled reactivity and established hydrolysis kinetics support efficient transformations into aldehyde and alcohol derivatives mimic natural aromatics. Our dedicated technical QA verifies residue and compliance with food-contact regulations.

    Industry compliance standards

    • FCC (Food Chemicals Codex) and JECFA safety evaluation for flavor intermediates
    • IFRA (International Fragrance Association) Code of Practice for safe use in perfumery
    • EU Regulation (EC) No 1334/2008 for food flavorings
    • ISO 22000:2018 Food Safety Management System for ingredient producers

    Typical usage ratio

    • 0.5–1.8% w/w in initial batch mixture; selected according to targeted aroma note intensity, and adjusted for permitted maximums per regional flavor and fragrance use limits

    Downstream process integration

    • Added during the primary condensation and hydrolysis stage under monitored pH to maintain optical purity of final aromatic alcohols and aldehydes

    Final product types

    • Fine fragrance compositions for perfumery
    • Food-approved artificial and nature-identical flavors
    • Complex compound aroma concentrates for beverages and confectionaries

    5. Specialty Monomer Synthesis for Modified Acrylics

    In the production of high-value acrylic monomers, this malonate derivative provides a controllable chain branching route allowing for synthesis of premium performance copolymers. Material performance data supports its inclusion in specialty resin formulations aimed at automotive coatings, adhesives, and functional films where molecular weight distribution and glass transition temperature require tight control.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management for resin synthesis
    • EN 71-3 Toy Safety Directive (for indirect contact in coatings)
    • ASTM D2567 for acrylic acid ester analysis
    • REACH pre-registration for monomer intermediates

    Typical usage ratio

    • 12–20% w/w based on acrylic precursor feed, precisely dosed to achieve specified acrylate branching and viscosity profile

    Downstream process integration

    • Added to the esterification reactor immediately following initial acrylic acid/alcohol combination, enabling controlled side-chain modification before final polymerization step

    Final product types

    • Automotive OEM and refinish coatings
    • Water-based and solvent-borne acrylic adhesives
    • Protective films, optical grade acrylic sheets
    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing Diethyl Ethyl(1-Methylbutyl)Malonate: Stepping Forward in Precision Chemistry

    Building Reliability Through Chemical Craftsmanship

    In the field of fine and specialty chemicals, our journey as a manufacturer always sharpens around the details—the ones that separate routine performance from true dependability. Working in physical plants, handling raw materials and reactors, we become deeply aware of how every impurity or inconsistency translates directly into the daily work of our customers. This mindset led us to commit ourselves to the precision required in making compounds like Diethyl Ethyl(1-Methylbutyl)Malonate, sometimes shortened to DEEMBM. Real product quality starts where batch sheets end: scale-up, repeated runs, and adaptation to changing market needs force ingenuity. Our team sees this chemistry not as copy-paste commodity work, but as a craft. In each batch, measurements, time, and technique define results you can feel, smell, and use confidently.

    What DEEMBM Means in Applied Chemistry

    Every class of malonate brings potential, but DEEMBM provides a tailored structure with both volatility and purposeful branching. Its backbone—anchored by the ethyl and 1-methylbutyl substituents—gives it an edge. We often refer to this compound as a reliable option for those searching for functionality beyond what the more ordinary diethyl or dimethyl malonates provide. From our view, DEEMBM isn’t used just because it exists; it wins out because its structure really solves some bottlenecks in both process and product performance across multiple applications.

    Our long days on the production line—and longer nights optimizing purification—lead to a product that integrates smoothly into alkylation, condensation, and cyclization steps. The chemical’s balance between reactivity and steric hindrance allows for nuanced syntheses, which our customers in flavors, pharmaceuticals, agrochemical research, and new materials value. As a direct manufacturer, we see the requests, complaints, and technical feedback first-hand. Over time, our plant operators learn that slight changes in distillation temperature or raw material sourcing impact downstream results. These lessons became key to not only matching but anticipating the technical needs of research chemists and process engineers worldwide.

    Specifications That Matter to Real Users

    Purity is one point, but we focus on the things that show up in the lab and in the field. Our batches of Diethyl Ethyl(1-Methylbutyl)Malonate regularly surpass industry benchmarks for low water content, color, and acidity. You won’t find high levels of unknowns or secondary esters here—the kind that complicate workups and add hours to purification. The material flows easily. Viscosity and pour point are stable across typical storage conditions.

    Our lab tracks GC assay down to minute levels, not because specifications demand it, but because customers diagnosing yield problems point us toward issues that sometimes arise below the threshold of “good enough.” Over dozens of successive campaigns, we compile stability profiles under real shipment conditions, not just shelf simulations. These records inform tweaks to our synthetic route, where we refine timing and order of reagent addition, monitor for side reactions, and invest in refining post-treatment methods that consistently deliver a bright, clear liquid product without haze or odor contamination.

    A Chemical With Real-World Applications

    A handful of buyers come for DEEMBM intending to execute textbook malonate chemistry: dialkylations, Knoevenagel condensations, or the construction of branched cyclic scaffolds. Yet over years of working with users from small startups to global producers, we’ve watched the product head in interesting directions. With the branched 1-methylbutyl group, our compound demonstrates unique selectivity and control in reactions where steric accessibility saves steps or increases yield.

    Pharmaceutical research teams point out how this malonate allows the design of intermediates with greater pathway flexibility. In agrochemical discovery, formulators leverage the distinct molecular weight and boiling range—a direct result of the ethyl and 1-methylbutyl substituents—to reach new compounds for testing. Meanwhile, flavors and aroma specialists take advantage of its low background odor and adaptability in esterification routes, finding it integrates without muddying the olfactory profile of the final blend.

    Every year, our technical support fields unexpected questions as users in materials science, coatings, and even battery electrolyte research find novel uses for such a nuanced malonate. Direct feedback sparks us to explore aspects we once thought marginal, such as cold temperature performance during long-haul shipments or shelf-life differences tied to factory lot history. This two-way flow keeps our team realistic about claims—and always searching for the quiet variables that shape user success.

    True Quality Is Grown, Not Claimed

    From the first drum to the thousandth, consistency is our real currency. Automated control systems help, but experienced eyes and hands on the floor matter more in spotting the off-notes, residual traces, or deviations that can show up before a batch hits a spec sheet. Purity by number isn’t our only focus. We pay equal attention to physical behaviors seen during extended storage, repeated transfers, and actual use in gloveboxes or pilot lines. Our best results follow from iterative feedback—real-world failures as much as successes—and not just a check box on a release certificate.

    Bottlers and compounders have thanked us for clear, low-tint product that causes fewer fouling events in their pumps and transfer lines. Research chemists repeatedly comment on clean, reliable reaction profiles with our DEEMBM, sparing them time in column purification and reducing the number of scrapped batches. These experiences tell us the effort we pour into batch control, cleaning standards, and ongoing staff training pays off where it matters: in your flask, not just our bottom line.

    How DEEMBM Stands Out Among Malonates

    All dialkyl malonates share a core chemistry, but structure makes a difference in real processes. Diethyl Malonate and Dimethyl Malonate see more textbook mentions, yet our Ethyl(1-Methylbutyl) derivative delivers unique results. The branched side chain gives new synthetic possibilities—bypassing the usual drop in yield seen with more crowded alkylation sites. In practice, the volatility and solubility profile responds differently during vacuum distillation, letting users tailor workups more finely and sometimes recover intermediates with less thermal degradation.

    Compared side by side in multi-step syntheses, this compound’s reduced odor, controlled color, and resistance to byproduct formation translate into operational savings for both small batch research and semi-bulk manufacturing. Over hundreds of real projects, our customers report higher tolerance to process fluctuations and easier downstream isolation. This helps not just in bench-scale chemistry but also in pilot plants, where every inconsistency raises cost and timeline risk.

    Our experience tells us that DEEMBM fits best in demanding contexts—where a subtle change in alkyl group influences everything from solubility to coupling selectivity. For enterprises already frustrated by inconsistent diethyl or dimethyl malonates, or for those seeking to push boundaries in chemical synthesis, our product steps up as a worthy alternative.

    Challenges and How We Answer Them

    Every advancement comes with new hurdles. At scale, we’ve seen that sourcing high-purity starting alcohols and dialkylating agents for such a specialized product takes vigilant supplier management and in-house pre-treatment. Equipment fouling and batch contamination turned up early in our scale-up phase; we worked through these by refining intermediate washes and investing in process automation that still leaves room for human intervention when anomalies are spotted.

    Disposal and safety in handling DEEMBM also raised valid feedback from the people who actually measure, pour, and blend the chemical. Taking these concerns seriously, we focus on providing extensive usage guidance and technical support—not boilerplate, but expert advice drawn from operators who know what it's like to face a wall of unknowns on the floor.

    As export markets grew, we navigated regulatory challenges regarding shipment, labeling, and country-of-origin tracing. Our quality and logistics teams prepare real-time documentation backed by extensive batch records, helping our clients save time and avoid headaches with customs or internal tracebacks. These routines protect our product’s integrity through real-world shipments, not just theoretical cold-chain simulations.

    Supporting Our Clients Beyond the Sale

    Buying DEEMBM direct from a manufacturer opens up far more than access to inventory. Our technical and production teams understand customer constraints—unexpected plant shutdowns, late-stage formulation changes, hard-to-predict project pivots—because we live those same cycles. We maintain open lines to discuss formulation troubleshooting, impurities, and high-stress deadlines. Our regular user group meetings, either online or face-to-face, give customers a platform for direct feedback.

    Sometimes delivery pressures force hard choices, like rerouting batch shipments or adapting on short notice to changing specs. Here, our years of in-house experience with scale, risk, and supply reliability come into play. Rather than hiding behind an email helpdesk, we commit to real-time conversations and hands-on technical participation where it's most needed. This ongoing engagement helps surface silent pain points and hidden process wins, fueling innovation that comes from collective know-how, not just top-down decisions.

    Looking to the Future: A Partnership Over a Product

    The chemical industry, and specialties like DEEMBM, are never static. Customer requirements shift fast—environmental regulations, consumer preferences, and advancement in synthetic chemistry all demand continuous change. As a manufacturer, we don’t chase every passing trend but we stay ready to modify synthesis or adapt purity benchmarks when science or regulation requires it.

    Regulatory compliance matters. Internally, we keep our documentation up to date and invest in employee training to stay current with international standards. Risk mitigation—from exposure prevention to waste stream control—runs deep in our standard operating procedures. The goal is not just legal safety, but lasting trust built with the engineers and scientists relying on our product every cycle.

    Customers look toward us for early information about upcoming changes or improvements. As a result, we stay transparent with updates and discuss any anticipated shifts in the supply chain or regulatory environment that might influence their own projects. By sharing our technical journey—from raw material challenges to final test results—we give our users more than a shipped drum; we offer a window into the thought, labor, and expertise invested in every kilogram.

    What Sets Our Work Apart in Malonate Chemistry

    In a world flooded with copycat producers and product spec sheets that look alike, reliability and customer-centric thinking become the sharpest advantages. Our satisfaction doesn’t come from the volume shipped, but from the technical questions that test what we know and push us to learn more. Each process deviation or unexpected feedback triggers troubleshooting, targeted experiments, and direct engagement with those affected.

    For each product line—DEEMBM included—our core principle centers on achieving not just compliance, but technical excellence supported by real evidence. We track how small variations affect chromatographic purity, reactivity, and physical handling. Investment in analytical infrastructure allows our QC lab to run advanced purity screens and stability studies, not because auditors demand it, but because process chemists need to know what they’re actually working with day to day.

    Making Your Next Batch Better—Not Just Your Last

    Those handling Diethyl Ethyl(1-Methylbutyl)Malonate need more than a generic chemical. They need a true partner—one who listens, adapts, and acknowledges issues before they become roadblocks. Every drum carries not just our reputation, but the stories, research, and production bottlenecks of scientists and engineers worldwide. By staying curious, communicative, and honest in an industry that rarely gets the limelight, we bring real value to every connection and every chain reaction started in your facility.

    We haven’t solved every technical puzzle with DEEMBM, but commitment to reliability, transparency, and end-user support keeps us invested in the details—batch after batch, year after year. For a chemical that’s often just one building block among many, we’re proud that our product stands apart, supported by the evidence of real-world performance and customer trust.

    Bring us your application challenges. Share your toughest process restrictions. Our reputation as a direct manufacturer rests on overcoming those hurdles—together—with technical rigor, practical knowhow, and a deep respect for the science that drives industry forward.