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Diacetone-D-Glucose

    • Product Name Diacetone-D-Glucose
    • Alias DAG
    • Einecs 406-230-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    810603

    Productname Diacetone-D-Glucose
    Casnumber 14316-31-9
    Molecularformula C12H20O7
    Molecularweight 276.28 g/mol
    Appearance White to off-white crystalline powder
    Solubility Soluble in water and ethanol
    Meltingpoint 146-148°C
    Purity Typically ≥98%
    Boilingpoint Decomposes before boiling
    Storagetemperature 2-8°C
    Synonyms 1,2:5,6-Di-O-isopropylidene-D-glucose
    Smiles CC1(O)OC2C(O)C(O)C(O1)O2C(C)O

    As an accredited Diacetone-D-Glucose factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g Diacetone-D-Glucose is packaged in a sealed, amber glass bottle with a secure screw cap and a clear, labeled sticker.
    Shipping Diacetone-D-Glucose is shipped in tightly sealed containers, protected from moisture and direct sunlight. It should be stored in a cool, dry place and transported in compliance with relevant chemical safety regulations. Packaging ensures the chemical’s stability and integrity during transit to prevent contamination or degradation. Handle with appropriate personal protective equipment.
    Storage Diacetone-D-Glucose should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from moisture, heat, and direct sunlight. Keep the chemical away from incompatible substances such as strong oxidizing agents. Store at room temperature and ensure proper labeling. Avoid exposure to air to prevent degradation and always follow standard chemical safety guidelines.
    Application of Diacetone-D-Glucose

    Applications of Diacetone-D-Glucose in Industrial Manufacturing

    As a direct manufacturer of Diacetone-D-Glucose, we supply this specialty carbohydrate derivative for integration across several advanced industrial segments. The following use cases reflect established industry practices, specific regulatory compliance, precise formula incorporation, and typical downstream end products.

    1. Pharmaceutical Intermediate for Prodrug Synthesis

    Pharmaceutical processors utilize Diacetone-D-Glucose as a masked sugar fragment in the synthesis of specific glycosylated prodrugs, especially for improved pharmacokinetics of nucleoside and antiviral agents. Our material enables precise glycosylation steps, supporting protected glycosyl donor reactions under anhydrous conditions as required in multi-step API development.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 211 (U.S. FDA Current Good Manufacturing Practice)
    • European Pharmacopoeia (Ph. Eur.) general chapter 5.10
    • USP-NF Chapter <1078> for process validation

    Typical usage ratio

    • 10–35 mol% relative to core API precursor, adjusted during glycosylation stage based on yield, specific route and protecting groups

    Downstream process integration

    • Introduced into the glycosylation step as a protected sugar reagent; full deprotection occurs post-extraction prior to API purification

    Final product types

    • Antiviral prodrug APIs
    • Modified nucleoside analogues
    • Specialty carbohydrate-based intermediates

    2. Fine Chemical Synthesis: Chiral Building Block

    Organic synthesis labs and fine chemical plants deploy Diacetone-D-Glucose as a chiral synthon to introduce defined stereochemistry into medical imaging reagents, synthetic flavors, and agrochemical leads. Its high purity grade ensures reliable enantiomeric excess during catalytic or stoichiometric synthesis, supporting commercial batch consistency at scale.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System
    • REACH Regulation (EC) No 1907/2006 Registration for chemical handling
    • Chemical Facility Anti-Terrorism Standards (US DHS)

    Typical usage ratio

    • 5–30% w/w in starting reaction mixtures, optimized for target molecule complexity and yield targets

    Downstream process integration

    • Added during key asymmetric synthesis steps to impart chirality; often followed by selective cleavage and further derivatization stages

    Final product types

    • Diagnostic contrast agents
    • Synthetic menthol precursors
    • Chiral auxiliaries and ligands
    • Advanced intermediates for crop protection

    3. Food Additive and Encapsulation Matrix

    Food ingredient manufacturers employ Diacetone-D-Glucose as a processing aid for controlled-release microencapsulation of flavors, vitamins, and functional additives. Its exceptional film-forming capacity supports the creation of stable edible coatings. Regulatory frameworks strictly govern ingredient use, batch traceability, and safety assessment for food-contact applications.

    Industry compliance standards

    • Food Chemicals Codex 12th Edition (FCC)
    • 21 CFR Part 172—Food Additives Permitted for Direct Addition
    • FSSC 22000 Food Safety System Certification
    • EU Regulation (EC) No 1333/2008 on food additives

    Typical usage ratio

    • 1.5–6% w/w, determined by flavor oil or vitamin payload and desired release characteristics; validated via sensory and stability testing

    Downstream process integration

    • Employed during mixer granulation and film formation in encapsulated additive lines; included prior to spray drying or extrusion steps

    Final product types

    • Encapsulated food flavors
    • Protected micronutrient blends
    • Sustained-release sweetener tablets

    4. Industrial Coatings: Crosslinkable Sugar Resin Precursor

    Coatings formulators integrate Diacetone-D-Glucose into waterborne and solvent-free resins as a multifunctional hydroxyl donor, enhancing flexibility and reactivity during crosslink cures. Its controlled acetalization improves storage stability and resin conversion. Strict oversight applies under coatings industry environmental and production quality standards.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management for chemical manufacturing
    • ASTM D3029 (Standard for Nonvolatile Residue in Paints and Coatings)
    • EU Reach (Annex XVII) for industrial chemicals used in coatings

    Typical usage ratio

    • 3–12% by weight in final resin formulation, varied against crosslinker reactivity and physical film property targets

    Downstream process integration

    • Blended into resin kettle prior to polymerization or added during post-synthesis formulation of the reactive binder system

    Final product types

    • High flexibility industrial varnishes
    • Waterborne protective coatings for packaging
    • Low-VOC architectural finishes

    5. Analytical Reagent for Carbohydrate Derivatization

    Specialty laboratories use our Diacetone-D-Glucose as a derivatization agent for high-precision carbohydrate profiling in food and pharmaceutical quality control. Its specific diketone protection assists in pre-column derivatization, allowing reproducible and sharp chromatographic separations using HPLC or GC methods.

    Industry compliance standards

    • ISO/IEC 17025:2017 General requirements for testing laboratories
    • AOAC Official Methods for food carbohydrate testing
    • USP Chapter <621> Chromatography

    Typical usage ratio

    • 10–50 mg per mL sample, based on substrate abundance and detection limits of specific analytical protocols

    Downstream process integration

    • Added in the sample preparation stage, before chromatographic separation, to form stable derivatives detectable by UV or MS detection

    Final product types

    • Certified analytical standards
    • HPLC sample kits
    • Calibration solutions for regulated quality laboratories
    Free Quote

    Competitive Diacetone-D-Glucose prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

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    Certification & Compliance
    More Introduction

    Introducing Diacetone-D-Glucose: Quality You Can Track from the Factory Floor

    Diacetone-D-Glucose: Built by Chemists, Valued by Industry

    In our plant, a batch of Diacetone-D-Glucose never sails out the door without a thorough hands-on assessment. We know every drum’s journey from raw carbohydrate input to the final pure crystalline solid. We have watched partnerships deepen over the years, as formulators who once doubted new auxiliary materials now insist on verifying our model 98-01 by name. We appreciate this loyalty, because we are hands-on with our product from the start—no outsourcing the steps, no mystery intermediates. In our chemical world, consistency means something only because we see the process through to the end ourselves.

    What Sets Diacetone-D-Glucose Apart on the Factory Floor?

    Workers on our lines see tightly interconnected steps. Our Diacetone-D-Glucose begins with thorough carbohydrate selection, converting pure D-glucose through careful acetone condensation. Years of practice help our teams recognize the moment when crystallization reaches the right endpoint. We favor a model with a purity above 99% (model 98-01), filtered and dried under recurring inspection, and we confirm the melting point for each batch. Many producers miss these details but in practice, regular spot tests matter far more than theoretical numbers printed on a page. If you get a shipment from us, the crystals won’t clump. Storage holds up. Dust stays low, so feeding it into downstream blends doesn’t clog machinery or gum up feeders. Our finish means operators never need to worry about inconsistent pourability or color drift from a yellowing batch.

    Designed for Demanding Chemical Applications

    As a manufacturer, we recognize how technical staff rely on certainty at every stage of their process. In resin synthesis, clear films demand a low residual moisture content – we maintain it well below 0.2%, confirmed onsite. For solvent systems, solubility in a broad range of polar organic solvents often proves critical. Our Diacetone-D-Glucose dissolves rapidly, whether you’re mixing in methyl ethyl ketone or acetone blends. Process chemists count on predictable performance, batch after batch, especially when end-use requirements restrict variability. We’ve never delivered two shipments with a measurable difference in key performance attributes, not because of luck, but because we keep every process transparent and open for audit at our own facility.

    How Our Chemists Built a Repeatable Product

    Some differences matter more at manufacturing scale than they do in a lab notebook. We’ve learned that the crystalline structure, monitored by X-ray diffraction, needs a tight particle-size distribution to avoid separation in bulk mixing processes. If the material locks up at the wrong temperature, or if trace aldehydes sneak in, the entire downstream pathway starts showing defects—be it finish, stability, or clarity. Our teams solve these inconsistencies not just on the bench, but on hundred-kilogram mixers. We rely on spectroscopic analysis on each lot, but double-check against melting-point and loss-on-drying, because we know instrumentation alone cannot catch every anomaly. Over years of production, our internal quality checks, including odor, color, and residual impurity (proven below 0.1%), are written into operating manuals, not just buried in quality paperwork.

    Comparing Diacetone-D-Glucose to Alternatives

    For formulators evaluating supplementary carbohydrates and auxiliaries, Diacetone-D-Glucose often comes up alongside starch derivatives and simple sugar acetals. Our experience shows the diacetone group on the glucose molecule brings notable stability under both resin and crosslinker systems—far better than many reducing-sugar acetals, which break down under heat. Many customers tell us our Diacetone-D-Glucose stays clear and resists yellowing over years in storage, unlike conventional glucose acetals which sometimes degrade before a formulated product even leaves the warehouse. Compared with pentaacetylglucose, our product’s single-step process leaves a lower profile of acetyl group migration—resins stay flexible, and plasticizers disperse evenly; engineers see an improvement in shelf-life of coatings and films. We keep our own comparison data, because we’ve had clients send in competitor samples for side-by-side evaluation. Both experienced and new technical staff have pointed out tighter crystallinity, easier blending into tough solvent systems, and better downstream performance when choosing our Diacetone-D-Glucose.

    Meeting Industry Needs from Resin Formulation to Electronics

    Our journey with Diacetone-D-Glucose began decades ago serving synthetic resin producers. Processes have shifted. Now, high-purity grades are standard in electronics, inks, paints, construction materials, and specialized adhesives. The challenge for modern processors doesn’t end at chemical purity—handling, storage, and downstream compatibility make or break production lines. Chemists come to us looking for a reagent that not only integrates without clumping, but also endures months of planned storage and frequent re-dosing in continuous operations. Field engineers have tested our model 98-01 in waterborne coatings, noting clean film formation and low color rise under extended UV exposure. Colleagues in adhesive manufacturing report that adding our product at a late stage preserves clarity, with no precipitation or fogging during cure. Our experience with heat-cure and two-component resin systems has shown that Diacetone-D-Glucose resists hydrolysis, a problem that plagues direct glucose acetals.

    Health, Safety, and Best Practices

    From our first day, we adopted a safety-forward approach. We invest in sealed transfer systems, and train line staff to minimize any potential exposure. Our Diacetone-D-Glucose produces little dust, but operators wear protection, following regulatory guidance as a matter of pride. We track waste solvents and batch residues with the same intensity we aim at finished product quality. Not a single operator has reported a significant incident involving our material—our record proves hands-on attention makes a difference. Whenever a new client changes raw material grades, our technical support teams help retrain operators, treating early questions as critical feedback rather than “user error.” Our long experience indicates that providing full data sets, including storage recommendations and historical stability findings, actually saves costs—plant managers verify this every season.

    Building Trust through Traceability

    We never lose sight of the reality that every kilogram in the market carries our plant’s reputation. That’s why each drum leaves marked to a lot and precise test record. If a client ever questions performance, we trace the exact equipment and raw material batch. Practicing this level of traceability has forced us to upgrade testing and recordkeeping, but we’ve found it keeps all teams sharper. Transparency isn’t a slogan; it’s a practiced discipline—from our raw material selection all the way to final documentation audits and follow-up support for repeat orders. Auditors from downstream manufacturers tour our facilities several times a year, reviewing not just property sheets, but actual process logs and retained samples. We do not tolerate shortcuts or batch mislabeling, knowing full well that trust, once lost, is almost impossible to regain. Most of our oldest clients continue reordering simply because every shipment arrives with data attached to real people, ready for review.

    Continuous Improvement: Listening to User Experience

    We don’t just accept a good batch and move on. Meeting with production staff, especially in client plants, always brings surprises. Once, a routine site visit revealed that a customer had improved throughput by switching to our lot with slightly larger crystal size—easier flow at their high-speed impeller mixers. We immediately requested more details and adjusted a portion of our process line, offering tailored size fractions for their next runs. Success in our business grows from learning the real-world needs of each downstream user, whether that means changing packaging for better shelf stability or batch labeling for rapid inventory turnover. We have gone back to our reactors more than once, retooling steps because an end-user’s feedback highlighted a weak point in solubility or delivery. Taking action like this has kept us continuously improving, long after the original product launch. We consider it a privilege to adapt, not a chore.

    Supporting Innovation in Client Labs

    Part of our mission is working directly with development chemists—those who are always searching for ways to set new benchmarks. We’ve shared hundreds of kilos for pilot-scale trials over the years, helping teams refine processes for UV-cured films and biomedical resins using Diacetone-D-Glucose as a key building block. We’ve taken their feedback, sometimes returning to our own labs to run confirmatory experiments—what works in a three-liter flask sometimes reveals surprises at reactor scale. We maintain direct lines of communication between our technical leadership and client-side innovators, recognizing that breakthrough products usually arise from this kind of back-and-forth.

    Environmental Responsibility—More Than Regulatory Compliance

    We take environmental responsibility personally. Unlike some large-volume acetals produced from less-controlled sources, our entire process chain for Diacetone-D-Glucose uses certified starch or sugar feedstocks, with no tolerance for off-grade material. In our waste handling, we commit to solvent recovery and full reuse cycles. Waste by-products never leave our factory untreated and every year, internal audits identify new ways to cut both water and energy use. These steps cost time and money, but we believe customers sense the difference, not only in product quality but in a plant’s attitude towards stewardship. Regulators come through with checklists, but our real challenge has always been building trust with the communities around our facility, answered in part by keeping water, air, and byproduct emissions tighter than any minimum legal standard. That approach has not only kept us in long-term business—it has fostered local partnerships that support everyone’s well-being.

    Commitment to Research, Standards, and Progress

    Industry trends change. Researchers keep sending us updates as technical demands evolve, sharing novel resin systems or composite materials that call out for a flexible, stable, and reliable Diacetone-D-Glucose. We participate in professional networks and industry consortiums, contributing our long-term performance data and sharing successes from every sector, whether that’s in electronics encapsulation or flexible glass interlayers. Adhering to international specifications is only a start – we go further by entering annual proficiency testing, benchmarking every production run against global leaders. Our plant teams actively attend scientific conferences, both to present practical findings and to listen for what upcoming research might further refine about our product’s value, challenges, or novel uses.

    What We’ve Learned—And What We Can Offer

    Years of producing and supplying Diacetone-D-Glucose have taught us some simple truths. Clients trust less what is promised and more what is proven through results they can measure. Delivering reliable, high-quality chemical auxiliaries means watching every detail. Consistency, transparent records, and responsive support build lasting partnerships. When technical staff recommend our model 98-01 to their colleagues, it reflects not just the product’s chemical purity or processability, but shared trust earned on both sides of the delivery bay. Each improvement in handling, packaging, and technical data arises directly from daily conversations, not abstract strategy documents. That pragmatic experience—won through decades of collaborative problem-solving—is what drives us to maintain, test, and improve every lot we produce.

    Final Word: Diacetone-D-Glucose as a Reliable Partner in Progress

    Every bag of Diacetone-D-Glucose shipped from our plant carries more than a batch code—it represents technical skill, ongoing investment, and a promise made by people who stand behind every shipment. For our clients, that means less worry about fit, less downtime troubleshooting raw materials, and more focus on making progress in their own industries. For our teams, it means steady pride in their work and a continuing drive to deliver the best possible product, batch after batch. Diacetone-D-Glucose, made in our plant, finds its real value each time a chemist, engineer, or line operator discovers their work moves forward, reliably and predictably, with each delivery. That daily progress is the standard by which we measure ourselves before any order leaves the loading dock.