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D-Tyrosinol Hydrochloride

    • Product Name D-Tyrosinol Hydrochloride
    • Alias H-D-Tyr-ol·HCl
    • Einecs 871-818-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    927937

    Product Name D-Tyrosinol Hydrochloride
    Cas Number 102784-12-5
    Molecular Formula C9H14ClNO2
    Molecular Weight 203.67 g/mol
    Appearance White to off-white powder
    Purity Typically >98%
    Melting Point 192-195°C
    Solubility Soluble in water
    Storage Temperature 2-8°C (refrigerated)
    Optical Rotation [α]D +20° to +25° (c=1, H2O)
    Synonyms D-(+)-4-Hydroxyphenylglycinol hydrochloride
    Iupac Name (R)-2-Amino-3-(4-hydroxyphenyl)propan-1-ol hydrochloride
    Ph 4.0-6.0 (10 mg/mL in water)
    Hazard Class Non-hazardous (for transport)

    As an accredited D-Tyrosinol Hydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing D-Tyrosinol Hydrochloride, 5 grams: Supplied in a sealed amber glass vial with tamper-evident cap and moisture-resistant labeling.
    Shipping D-Tyrosinol Hydrochloride is shipped in tightly sealed containers to protect it from moisture and contamination. It is packaged with appropriate hazard labeling and documentation, following regulatory guidelines for chemical transport. The material is typically dispatched via reliable couriers with temperature and handling instructions to ensure product integrity during transit.
    Storage D-Tyrosinol Hydrochloride should be stored in a tightly sealed container, protected from light and moisture. Keep it at 2–8°C (refrigerated conditions) and away from incompatible substances such as strong oxidizers. Ensure proper labeling and storage in a well-ventilated, dedicated chemical storage area. Avoid prolonged exposure to air to prevent degradation and maintain chemical stability.
    Application of D-Tyrosinol Hydrochloride

    Applications of D-Tyrosinol Hydrochloride in Industrial Manufacturing

    D-Tyrosinol Hydrochloride serves as a critical intermediate and chiral building block in several specialized industrial sectors. As an original manufacturer, we supply this material to highly regulated downstream applications where its stereochemical properties, purity, and reproducibility directly impact product safety and function. Below, we outline the principal real-world industrial scenarios in which customers rely on D-Tyrosinol Hydrochloride, focusing on actual compliance demands, industrial process integration, and the resulting end products.

    1. Chiral Pharmaceutical API Synthesis

    Pharmaceutical manufacturers select D-Tyrosinol Hydrochloride as a chiral intermediate for the synthesis of complex drug substances, particularly those requiring high enantiomeric purity in their active pharmaceutical ingredients (APIs). The material enters multi-stage synthetic pathways for β-adrenergic blockers, certain antiviral agents, and neuroactive compounds. Downstream producers depend on validated supply chains and strict lot-to-lot consistency to maintain control over stereochemistry in their GMP-regulated environments.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211 (cGMP for Finished Pharmaceuticals)
    • EU EudraLex Volume 4 GMP Guidelines
    • Relevant monographs in the United States Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.)

    Typical usage ratio

    • Generally 0.7–2.0 moles per mole of target API precursor, depending on synthetic step and desired chiral yield; adjustment based on reaction scale, desired purity, and route-specific kinetics.

    Downstream process integration

    • Introduced at the chiral amine or amino alcohol coupling stage, frequently during hydrogenation, reductive amination, or amidation; subsequent protecting group removal and purification occur prior to downstream formulation.

    Final product types

    • Enantiopure beta-blockers (e.g., esmolol derivatives)
    • Stereospecific antiviral drug intermediates
    • Chiral CNS-active pharmaceutical substances

    2. Peptide Synthesis Reagents

    Custom peptide manufacturers require D-Tyrosinol Hydrochloride as a specialty protected amino alcohol source for the preparation of synthetic peptides with modified side chains. Its integration supports selective residue incorporation and functionalization in solid-phase or solution-phase peptide synthesis. The chiral nature ensures correct stereoregular assembly and enables the production of high-purity research-grade or clinical-grade peptide APIs.

    Industry compliance standards

    • US FDA 21 CFR Part 210/211 (GMP for Pharmaceutical Manufacturing)
    • ISO 9001:2015 Quality Management Systems
    • USP <1047> Good Peptide Manufacturing Practices
    • Guidelines as per the European Directorate for the Quality of Medicines & Healthcare (EDQM)

    Typical usage ratio

    • Ranges from 0.5–1.1 equivalents per peptide incorporation cycle, modulated by residue sequence length and protection/deprotection protocol; small excesses may ensure reaction completion without substantial waste.

    Downstream process integration

    • Utilized in initial condensation cycles as a protected residue or at later stages for side-chain modification; followed by cleavage from resin, purification with HPLC, and lyophilization for downstream use.

    Final product types

    • Modified synthetic peptides for therapeutics
    • Diagnostic peptide standards
    • Research-grade functionalized peptides

    3. Bioactive Compound Development for Fine Chemicals

    In the fine chemicals sector, D-Tyrosinol Hydrochloride is introduced as a chiral precursor during the synthesis of agrochemical active ingredients and custom chiral auxiliaries. Industry users rely on its precise molecular configuration to impart desired biological activity, particularly in areas requiring regulatory traceability and reliable scalability for pilot-to-plant operations.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for chemical registration in Europe
    • ISO 9001:2015 for chemical processing traceability
    • OECD Guidance for Good Laboratory Practice (GLP), where relevant
    • National agrochemical registration guidelines (for downstream application)

    Typical usage ratio

    • Adopted at levels of 0.2–1.5 molar equivalents per synthetic target; ratio tailored for conversion efficiency and desired chiral outcome within the process route.

    Downstream process integration

    • Charged during key stepwise transformations—such as enantioselective reductions, asymmetric substitutions, or as an auxiliary in chiral pool synthesis schemes—prior to final derivatization and downstream scale-up.

    Final product types

    • Enantiopure agrochemical intermediates
    • Custom chiral auxiliaries for process development
    • Specialty fine chemical building blocks

    4. Analytical and Reference Material Production

    Manufacturers synthesizing certified reference materials and analytical standards incorporate D-Tyrosinol Hydrochloride as a traceable enantiopure marker compound. Its well-characterized NMR and chromatographic profile enables downstream users to calibrate analytical instruments and validate methods for chiral resolution and quantification, directly supporting laboratories working under regulated conditions.

    Industry compliance standards

    • ISO 17034:2016 General Requirements for the Competence of Reference Material Producers
    • ISO/IEC 17025:2017 Testing and Calibration Laboratories
    • US Pharmacopeia (USP) and European Pharmacopeia (Ph. Eur.) reference standard requirements
    • OECD GLP principles for test substances

    Typical usage ratio

    • Prepared at purity levels typically exceeding 99.5% and formulated as stock solutions between 1–10 mg/mL for intended analytical application; mass balance adjusted to final fill volume required by laboratory end users.

    Downstream process integration

    • Dissolved at precise concentrations, often with isotopic labeling or additional characterization steps; packaged following certification and traceability audits before dispatch for laboratory quality assurance programs.

    Final product types

    • Certified chiral reference standards
    • Analytical calibration solutions for HPLC/UPLC/GC
    • Traceable markers for pharmaceutical and food testing laboratories
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    Certification & Compliance
    More Introduction

    D-Tyrosinol Hydrochloride: An Insight from the Manufacturer

    Introduction to D-Tyrosinol Hydrochloride

    Every batch of D-Tyrosinol Hydrochloride in our facility starts with a clear commitment: to offer purity and reliability for advanced research and manufacturing. This compound does more than fill a place on a chemical catalog. Driven by decades in the industry, we see D-Tyrosinol Hydrochloride as a key intermediate for innovators chasing breakthroughs in fields like peptide synthesis and pharmaceutical analysis.

    Product Model and Specifications

    Working on this chemical has meant upholding the tightest specifications. The material we produce, D-Tyrosinol Hydrochloride, commonly follows the stereochemical designation (R)-2-Amino-3-(4-hydroxyphenyl)propan-1-ol hydrochloride. For those working at the bench, this isn’t just textbook nomenclature. Stereoisomerism and absolute purity define outcomes in peptide coupling, and every research group and manufacturer relying on us counts on reproducibility across lots.

    Our standard lot targets a purity exceeding 98%, with most batches reaching higher. Moisture content follows through with carefully controlled drying protocols, keeping water below 0.5%. Handling sensitive, optically pure compounds brings regular scrutiny down to every step of our workflow. From vacuum packaging to real-time monitoring of environmental conditions, we lock in stability from our first process tank to your final assay.

    Usage: From the Chemistry Bench to Innovative Sectors

    D-Tyrosinol Hydrochloride holds a significant place in custom peptide synthesis and small molecule research. End users, ranging from early-stage biotech companies to public research institutions, turn to this compound because of its clean reactivity and established performance profile. In our daily work, we see its critical role in the preparation of compounds with precise stereochemistry. The primary alcohol group, paired with the amino and phenolic groups, opens up options for building sophisticated molecular architectures.

    Every kilogram shipped from our lines finds use in a specific reaction or process. Medicinal chemists use D-Tyrosinol Hydrochloride while building chiral ligands for drug targets. Some customers lean on it for biocatalysis, where chirality again shapes activity in enzymes. Analytical labs find value in our material as a reference standard, relying on our certificate of analysis and batch consistency for credible, reproducible results.

    One overlooked aspect relates to downstream process flexibility. The hydrochloride salt form brings manageable solubility profiles in aqueous and certain mixed-phase systems. Solubility and handling advantages make a crucial difference when moving from benchtop protocols to pilot-scale or regulated manufacturing environments.

    Our Experience: The Story Behind Every Batch

    Experience in manufacturing impacts more than numbers on a specification sheet. Over years, we've grappled with the material’s sensitivity to moisture and light. Our team has seen early days, when even slight process drift or environmental exposure altered melting point or color. Those lessons shaped the current setup, with closed reactors, nitrogen-purged environments, and fast tracking through post-synthesis purification.

    Packing D-Tyrosinol Hydrochloride brings its own challenges. Too many times, shipments in subpar packaging risk caking, degraded purity, or cross-contamination. Our switch to specialized antistatic liners, combined with desiccant controls, cut spoilage rates and holds purity readings batch after batch. Every adjustment follows direct feedback from users—one research site notes if solidification occurs after a month or if the expected spectral data stays consistent.

    Batch documentation and traceability never felt like paperwork for its own sake. Once, a customer tracked a minor, recurring analytical outlier to a trace impurity. From that moment, we doubled down on integrating mass spectrometry into release testing. Years later, it’s clear that real-world use cases, not hypothetical frameworks, shape what matters on the bench and in commercial production.

    Differences from Other Products: Why D-Tyrosinol Hydrochloride Stands Out

    A lot of chemists question the difference between D-Tyrosinol Hydrochloride and racemic tyrosinol or its L- isomer. It seems subtle until you see the impact in asymmetric synthesis. The (D)-enantiomer, prepared under carefully monitored chiral conditions, produces products inaccessible from non-chiral or L- precursors. Peptide synthesis and drug discovery depend on this precision, especially when chirality can mean the difference between active and inactive compounds.

    The hydrochloride salt form merits discussion. Free base forms, though widely available, often introduce headaches in solubility and batch-to-batch consistency. We watched numerous customers try to work around these hurdles, only to conclude that switching to our hydrochloride salt cuts experimental variability and simplifies handling protocols. The salt gives predictable solubility in both water and polar organics, and with proper storage, it holds up through multiple process steps with minimal form change.

    Available market alternatives, including lower grade materials or non-pharma-grade sources, fall short when the project moves to regulated spaces. The supply chain for D-Tyrosinol Hydrochloride never feels routine—discerning buyers know the risk of inconsistent quality, undetected enantiomeric impurities, or leachables from industrial packaging. Building a supply chain free from these recurring frustrations, we see value in detailed, transparent documentation and open communication. Customers trust us to flag even marginal shifts, rather than sweep inconvenient findings under the rug.

    Sourcing, Reliability, and Building for the Future

    Many of our trusted users come back year after year because reliability stands at the center of true manufacturing. With continued demand for new chiral building blocks and customized starting materials, the pressure only grows to ensure availability and support collaborative development. Chemists don’t just buy grams of compound—they rely on assurance that tomorrow’s reaction won’t get derailed by an outlier lot or forgotten stability data point.

    Over time, it’s clear that a low price-point version of D-Tyrosinol Hydrochloride, produced without serious oversight, risks more than budget overruns. Failed experiments cost teams momentum, and inconsistent inputs put timelines and outcomes in jeopardy. That’s where a true partnership between user and manufacturer begins. Transparent purity data, established quality controls, and openness about production methods give everyone from the lab chemist to the site manager confidence to scale.

    Many users push us on process innovation. We invested in scalable synthesis protocols and automated purification, not just to keep up with volumes but also to cut waste streams and improve green chemistry profiles. For suppliers to thrive, these investments can’t just be an afterthought—they carry through in solvent recovery, controlled energy use, and building audit trails that make regulatory review more straightforward.

    Supporting Advanced Research: How Our D-Tyrosinol Hydrochloride Makes an Impact

    We talk to customers in pharmaceutical R&D, biotech startups, and academic groups seeking new applications for active chiral intermediates. The footprint of D-Tyrosinol Hydrochloride widens as more complex drug targets come into focus, particularly those requiring tight stereochemical control. Early on, most demand centered on peptide modification. More recently, we've seen new interest in stereospecific synthesis for metabolites, natural products, and advanced materials applications.

    By providing dependable D-Tyrosinol Hydrochloride, we assure teams their fundamental building block won’t be the bottleneck. Teams reverse-engineering enzyme functions or mapping SAR for receptor agonists often start with our product. It’s a straightforward yet critical piece of advanced research. A successful project often tracks back to tiny differences in reactivity and selectivity—qualities defined right from our synthetic route.

    We value our long-term collaborations. Bringing new derivatives and alternative commercialization forms to the market, we draw on user feedback and share data openly. Joint method development, even custom-tailored specifications, emerge from sustained dialogue—not top-down marketing, but ground level collaboration. Each successful application builds both our expertise and our customers’ trust.

    Production Challenges and Solutions

    Making D-Tyrosinol Hydrochloride at scale introduces far more than the theoretical obstacles found in textbooks. Stereochemical control, purity, and stability challenge our process engineers daily. Years ago, we worked with open crystallization; now, everything runs closed loop, with inline spectroscopy ensuring transformation completeness and enantiomeric purity. Process validation includes extensive retention sampling and cross-batch comparison. Every equipment upgrade, from reactor controls to HPLC platforms, has a direct impact on final product quality.

    Not every phase has been smooth. Early scale-up efforts uncovered bottlenecks as reflux conditions silently deviated from bench protocols. By introducing robust analytical oversight, our teams can catch off-spec formation before it escalates. Over time, these lessons accumulate—so each operator, technician, and process leader carries practical knowledge forward. Continuous improvement, then, is not a slogan but an everyday practice woven through production, QC, and logistics.

    Quality Assurance That Goes Beyond the Lab

    Our investment in robust analytical infrastructure doesn’t just check a regulatory box. It’s an everyday tool. Every drum and bottle leaves our facility with documented chromatograms and spectral data. Customers tell us this transparency removes friction, especially when audits or regulatory oversight come into play. Our analysts match specifications for identity, purity, and moisture, and track stability using accelerated aging protocols that fit real transport and storage conditions.

    Unlike bulk traders, our QC chemists dig into root causes if something drifts slightly off trend. Citing data alone doesn’t answer what end users need. Cross-referencing spectral signatures and sharing batch histories allow confident troubleshooting when users run into unexpected reaction outcomes. That willingness to go the extra mile for understanding has saved countless hours for teams down the line.

    Handling, Storage, and Practical Experience

    D-Tyrosinol Hydrochloride’s handling finds its rhythm through practice. In our facilities, operators work in dehumidified, clean environments to prevent caking. Over time, small procedural changes—swapping ordinary polypropylene bags for antistatic, low-leachate liners—paid back dramatically. Experience proves that maintaining robust packaging standards carries through to every downstream user.

    Storage extends beyond standard recommendations. A properly packaged material lasts under dry, cool conditions without drifting from initial analytical results. Shipping can bring surprises, from temperature excursions to vibration-induced settling, so we overbuild our transport packaging to ensure every shipment arrives ready for immediate use. Routine QC checks on retained samples months later show our system works, matching release data every time.

    Users remark on the difference between working with material handled thoughtfully and shipments that lose consistency after transfer or storage. It’s these stories that led us to expand our support with tailored storage guidance, frequent retraining for logistics staff, and detailed material compatibility advisories. Problems like package dusting or label smudging, though small, receive real attention; too often, these “minor” missteps cause major delays in high-stakes projects.

    Listening to Feedback and Evolving with Industry Needs

    Direct contact with users tells us more than months of market research. Every customer query or complaint builds our readiness for next-generation requirements. Questions on packaging specs, data interpretation, and alternate forms come through our technical lines. Taking these seriously reshaped our support approach. We keep communication open—a two-way street where the user’s on-the-ground experiences guide our process enhancements.

    From shifting regulatory requirements to unexpected supply disruptions, we learn what’s needed and adapt our protocols. Addition of in-process analytics, better documentation of trace impurities, and flexible batch sizing come from outside input more than internal planning. Partnerships with research teams prompted us to explore new salt forms, alternative packaging, and custom labeling—all rooted in frontline feedback.

    Building this cycle of improvement means mistakes prompt action, not corporate platitudes. That approach sets us apart in an industry where the human side too often fades behind specifications and white papers. For every batch shipped, there’s a manufacturer who cares to listen, adapt, and deliver more than just a number on a spreadsheet.

    Conclusion: Real Substance Behind Every Package of D-Tyrosinol Hydrochloride

    Each drum or vial of D-Tyrosinol Hydrochloride shares the trace of hundreds of decisions—safety checks, process tweaks, years of refinement in making a tough molecule not just available, but dependable. On the manufacturing floor, every sight glass reading, every packed box, and every customer note shapes what arrives on your bench or in your reactor. Without shortcuts, with direct human experience, and with an open door for both praise and criticism, we put real meaning behind every kilogram shipped. That’s our commitment today and for the future of chemical manufacturing.