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D-Methioninol

    • Product Name D-Methioninol
    • Alias 2-Amino-4-methyl-1-butanol
    • Einecs 259-600-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    970504

    Product Name D-Methioninol
    Cas Number 2142-06-1
    Molecular Formula C5H13NOS
    Molecular Weight 135.23
    Iupac Name (R)-2-amino-4-methylsulfanylbutan-1-ol
    Appearance White to off-white solid
    Solubility Soluble in water
    Melting Point 35-37°C
    Optical Rotation +18° (c=2, H2O)
    Boiling Point 235°C at 760 mmHg

    As an accredited D-Methioninol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing D-Methioninol is packaged in a 25g amber glass bottle with a secure screw cap and chemical-resistant labeling for safety.
    Shipping D-Methioninol should be shipped in a tightly sealed container, protected from light and moisture. It is typically transported at ambient temperature as a non-hazardous chemical. Ensure compliance with local and international regulations. Proper labeling and documentation are required for safe handling and to prevent contamination or degradation during transit.
    Storage D-Methioninol should be stored in a tightly sealed container, protected from moisture and light. Keep it in a cool, dry, and well-ventilated area, ideally at 2–8°C (refrigerated conditions). Avoid exposure to incompatible materials, such as strong oxidizers. Proper labeling and secure storage help prevent contamination and ensure chemical stability. Always follow relevant safety guidelines and local regulations.
    Application of D-Methioninol

    Applications of D-Methioninol in Industrial Manufacturing

    D-Methioninol, as a differentiated chiral amino alcohol, serves as a critical intermediate and additive in several targeted sectors. Our manufacturing-grade D-Methioninol supports high-spec industrial customers in life sciences, advanced synthesis, and nutritional ingredient production. Below we outline verified downstream application scenarios, process integration points, and compliance requirements tailored for professional buyers and formulators.

    1. Chiral Intermediate for Pharmaceutical API Synthesis

    Pharmaceutical manufacturers adopt D-Methioninol for asymmetric synthesis of specialty APIs, particularly in routes requiring stereochemical purity. Its intermediate role includes use in constructing beta-methionine derivatives or as a chiral building block in preparation of targeted small-molecule drugs, where enantiopure content is essential for regulatory compliance and downstream pharmacological activity.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP–NF and Ph. Eur. monograph requirements for relevant API intermediates
    • FDA 21 CFR Part 210/211 for pharmaceutical ingredient processing
    • ISO 9001:2015 Quality Management Systems

    Typical usage ratio

    • 0.8–1.3 molar equivalents relative to the target intermediate, adjusted by route yield and impurity profile optimization

    Downstream process integration

    • Direct addition during chiral synthesis steps, used in enantioselective alkylation, reductive amination, or as a protected intermediate stage

    Final product types

    • Chiral pharmaceutical APIs for antivirals, cardiovascular, or CNS applications
    • Regulatory-grade API intermediates for further downstream synthesis partners

    2. Nutritional Ingredient for Animal Feed Fortification

    Compound feed and premix producers incorporate D-Methioninol as a bioavailable methionine source, especially in aquaculture and poultry nutrition. The compound supports precise amino acid balancing strategies, enabling enhanced animal growth rates and optimized protein utilization while minimizing nitrogen excretion in intensive farming systems.

    Industry compliance standards

    • FAMI-QS Code of Practice for Feed Additives and Premixture Operators
    • EU Regulation (EC) No 1831/2003 on additives for use in animal nutrition
    • AAFCO Official Publication (USA) – Amino Acids as Feed Ingredients
    • ISO 22000:2018 Food Safety Management Systems

    Typical usage ratio

    • 800–1800 mg per kg feed, dependent on species, growth stage, and existing methionine balance

    Downstream process integration

    • Integrated during premix compound blending immediately prior to pelleting or extrusion, with dosing carefully metered to maintain declared feed specifications

    Final product types

    • Poultry and swine compound feed
    • Specialty aquafeeds for intensive fish and shrimp operations

    3. Precursor for Agrochemical Synthesis

    Agrochemical formulators utilize D-Methioninol as a specialized precursor in the process routes for selective synthesis of plant growth regulators as well as stable sulfur-containing bioactive agents. Its structure provides controlled introduction of amino and thioether functionalities, contributing to biocompatibility profiles required in regulated agricultural chemicals.

    Industry compliance standards

    • OECD Principles of Good Laboratory Practice (GLP) for agrochemical development
    • REACH Regulation (EC) No 1907/2006 for chemical registration in the EU
    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS) for synthesis intermediates
    • ISO 9001:2015 for chemical supply chain management

    Typical usage ratio

    • 3-7% by weight of total precursor blend, precisely matched to the stoichiometric demand of downstream coupling reactions

    Downstream process integration

    • Engaged in controlled batch synthesis steps involving nucleophilic substitution or amidation, supporting post-reaction isolation and purification protocols

    Final product types

    • Plant growth regulator technical concentrates
    • Sulfur-based crop protection agent intermediates

    4. Active Intermediate for Enzyme Substrate Synthesis in Diagnostics

    Diagnostic reagent manufacturers rely on D-Methioninol as a substrate precursor for custom enzyme-linked assays. It enters specialty syntheses in the development of chiral diagnostic substrates used for colorimetric or fluorometric quantification of enzyme activity in clinical, biochemical, or food testing applications, demanding batch-to-batch high optical purity.

    Industry compliance standards

    • ISO 13485:2016 Medical Devices – Quality Management for IVDs
    • CLSI (Clinical & Laboratory Standards Institute) protocols for reagent development
    • Good Manufacturing Practices for In Vitro Diagnostics (IVD) Reagents
    • Specific customer QMS for analytical-grade substrate intermediates

    Typical usage ratio

    • 25–60 μmol per substrate batch unit, with final quantity adjusted for substrate turnover rate and target assay sensitivity

    Downstream process integration

    • Added to reaction vessels during substrate formation, followed by chromatographic refinement and lyophilization for IVD component assembly

    Final product types

    • Chiral enzyme substrates for quantitative clinical assays
    • Reference reagents for biochemical diagnostic kits
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    Certification & Compliance
    More Introduction

    Introducing D-Methioninol: The Next Step in Amino Alcohol Innovation

    Experience Informs Every Batch

    Decades of working with amino alcohols have taught us that every improvement in molecular structure leads to real changes in the field or the factory. D-Methioninol stands out as a product of focused research and continuous feedback from customers who use it daily. It’s a fine example of how chemistry refines nature’s building blocks to help businesses grow, products last longer, and processes work better. Our facility runs on the principle that every molecule we produce is more than a chemical—it’s a solution to someone’s problem, whether that involves animal nutrition formulation, fermentation optimization, or a specialty synthesis step.

    The Unique Identity of D-Methioninol

    D-Methioninol appears at first glance to belong to the familiar family of methionine analogs, but it carves out a clear identity both chemically and functionally. Structurally, it represents a hydrogenated analog of D-methionine itself, which brings a different hydrophilicity and reactivity profile to industrial applications. Many production colleagues have noted the change in process flexibility when shifting from a standard methionine source to D-Methioninol, especially when handling issues that crop up during blend stability and process moisture sensitivity.

    The Model We Manufacture

    Our standard model distinguishes itself with a purity benchmarked at no less than 98.5% by HPLC analytical trace, consistently confirmed by in-house and accredited third-party labs. Granular formulations don’t always work for customers handling viscous or liquid feeds, so we keep both powder and crystalline forms available, produced under inert atmosphere to keep the aldehyde function protected until use. Packing lines run under strict controls to prevent cross-contamination—standard food and pharma-grade polyethylene bags and drums serve most users’ needs.

    Specifications: Precision Meets Reliability

    Each batch of D-Methioninol runs within a target melting range of 67–71°C, and the pH in saturated solution holds tightly between 6.0 and 7.0. Water solubility allows complete dissolution at standard livestock feeding rates, and we verify below-threshold levels of heavy metals, residual solvents, and microbial counts. This work doesn’t just come from regulatory pressure; over the years, users have shown us why hidden trace elements can lead to batch failures or off-flavors in downstream products.

    Hands-On in Application: Where and How It Works Best

    Animal nutrition formulators look for consistent bioavailability and ease of mixing. D-Methioninol enters feed blends with predictable absorption, benefiting non-ruminant livestock who can’t synthesize methionine themselves. We’ve watched nutritionists test new rations for broilers and swine, and the feedback circles back to our process: integrity from storage to mixing straight to improved growth rates. Biotech engineers working in fermentation find that the reduced sulfur oxidation risk with D-Methioninol makes it easier to manage culture health; many report lower foam levels and smoother downstream purification.

    Specialty chemical manufacturers often use D-Methioninol as an intermediate in syntheses where a reducing methionine source saves trouble down the line. One project with a major European customer involved replacing conventional methionine with our compound, and their yield reproducibility numbers told the story long before the next year’s contract rolled around.

    How D-Methioninol Stands Apart from Other Methionine Sources

    Traditional D-methionine and DL-methionine feed supplements supply the essential amino acid but differ in chemical kinetics and solubility compared to D-Methioninol. Methionine hydroxy analogues, often sold for liquid feeding and acidulant properties, lack the hydrogenated functional group, and our product’s chemical profile provides improved shelf-life without the acid hydrolysis risk on prolonged storage. Over several years of batch retention testing, D-Methioninol has shown less tendency for caking or yellowing under standard warehouse conditions—a significant benefit for bulk users in hot or humid climates.

    Our process engineers point out that D-Methioninol, while comparable to classic counterparts by amino count, behaves distinctly in both water-based feeds and organic syntheses relying on reductive environments. The structural difference delivers actual process benefits, not just marginal numbers: faster wetting, more stable pH, and easier integration with micro-ingredient carriers. Compounders appreciate the way it blends both physically and chemically—no hot spots, no traced oxidation.

    Production Know-How Drives Product Quality

    The people behind D-Methioninol count every batch as a demonstration of the knowledge earned on the production floor. At scale, we’ve learned that minor changes in raw material supply or reactor agitation alter the end result. This product’s consistency comes from daily calibration and batch-to-batch adjustment guided by real experience, not by textbook formula alone. Each shipment leaves with point-source analytical results, traceability back to lot-level, and open QC data for customer review.

    Temperature and humidity swings at storage facilities once threatened to ruin more than a few truckloads—years back before we perfected inert storing and improved moisture barrier packaging. Now, our team checks not only product purity before loading but the microclimate data inside transport vehicles destined for warm coastal areas and cold, dry continental crossings. The margin for error in active ingredients is thin; any slip on our end affects farm productivity and industrial synthesis.

    Listening to Feedback, Adjusting for Real-World Usage

    The heartbeat of real manufacturing lies in the feedback loop. Our partnerships with animal feed mills, fermentation experts, and specialty compounders inform every process review. Feed plant managers have sent samples back, pointing out subtle flow issues or alternate blending protocols that led us to retool particle size distribution and anti-caking ingredient selection. Fermentation specialists described foaming or odor issues during scale-up, leading to investments in ultra-low-odor refining steps.

    One customer’s ruminant trial showed unexpected palatability shifts early in adoption, and their team’s report changed how we set batch aroma specifications. A group of Japanese biotechnology collaborators flagged the importance of extremely low transition metal contamination for their specific enzyme processes; this now forms a permanent part of our release criteria. The cumulative effect is a product that works in real-world conditions, not just in the QC lab.

    Stringent Quality: No Corners Cut

    Experience in chemical manufacturing has shown us that shortcuts at any stage eventually show up as failures in customers’ plants. We source precursors from long-standing partners only, each supply chain audited on the ground. Each tank, valve, and blending paddle gets regularly validated for chemical compatibility and trace carryover. In our last production line upgrade, we opted for stainless or FDA-grade polymers at every transfer stage, even though the cost profile grew. Our chemists regularly contribute insights from the field, leading to constant adaptation—standard operating procedures reflect not just best guesswork, but the actual reality of mixing, granulation, and storage.

    Quality assurance teams run full-spectrum analysis each week, not just on finished product but on in-process intermediates, and review customer usage analytics against retention samples from archived lots. If an issue arises, our response is guided by traceable data and field experience. The costs of a recall or failed trial outweigh savings made by skipping steps or running equipment outside validated conditions.

    Environmental Responsibility in Manufacturing

    Manufacturing D-Methioninol means managing chemical input, waste streams, emissions, and energy use with equal care. The world of chemical production changed over the past decade; regulators and buyers expect more than lip service to sustainability. We have invested in closed-loop solvent recovery, and all process effluents pass through on-site treatment before release from the plant. By cutting down organosulfur waste and improving yield per batch, we’ve curbed both environmental impact and raw material costs.

    We benchmark our performance against both local environmental codes and the best-practices standards applied in Europe and North America, and the operations team regularly tours partner facilities to spot and adapt practical solutions. Our approach isn’t theory-driven: it’s based on actual energy meters, stack output readings, and customer audit results. The result is that D-Methioninol meets strict residue, odor, and contaminant limits without sacrificing throughput or reliability.

    Supporting Customers Through the Full Lifecycle

    Most users of D-Methioninol expect more than a product drop on their dock. We have a technical support crew with years of practical experience, whom new and long-standing customers contact directly. Nutritionists experimenting with feed inclusion rates rely on our data from actual livestock trials. Biotech engineers testing compatibility with new microbial strains receive detailed feedback drawn from in-house fermentation runs. Chemical compounders scaling up new processes sit down with our process chemists around actual, shared lab data—what works in theory gets measured against batch logs.

    We’ve seen cases where an off-spec batch in user plants sent teams scrambling for root cause, and a close partnership meant clear communication and rapid corrective action. Field observations have repeatedly shown the need to adjust protocol for mixing, dissolving, or coating, so we keep detailed best-practice guides ready and regularly update them to reflect what works, not just what’s been published.

    Continuous R&D, Steady Improvements

    Feedback from years of scale-up and commercial use tells us where to focus. Stable batch color, improved wetting, better free-flow properties, and less off-odor—all come from tweaks in reaction kinetics and finishing line conditions. We keep improving the control window upstream, so customers don’t meet surprises downstream.

    University partners studying the bioavailability of D-Methioninol in monogastric animals supply raw data from controlled trials, and we adjust our process for optimal uptake and conversion rates. Chemical engineers at specialty intermediate plants pass along notes on reaction specificity, encouraging projects that make downstream catalysis both cleaner and more selective. As co-suppliers in the value chain, we often learn that a seemingly minor shift—like reducing particle fines or changing pelletization moisture—makes the difference in an efficient, headache-free process.

    Reliability Built on Real Results

    In our line of work, reliability is earned. Every year brings in new demands from the field—from livestock producers requiring precision in dosing to specialty manufacturers demanding higher purity and controlled trace elements. Our team reviews every QC and customer performance report. Each complaint is logged, the issue tracked back to root cause, and the fix becomes a permanent process improvement. Some of the longest-standing users of D-Methioninol started as critics, now call on us for direct input in product development and process troubleshooting.

    Our production line isn’t run to make the cheapest product, but the one that fits both immediate and long-range customer goals: minimal product loss, no stability-driven waste, and compliance with increasingly tough market and regulatory standards. Equipment upgrades, staff retraining, and raw material audits happen regularly—not as a reaction, but as a reflection of what it takes to stay ahead in this field.

    Transparency, Documentation, and Traceability

    Customers today want to know both the roadmap and the journey behind their products. We support full documentation, including certificates of analysis, retained sample tracking, and comprehensive audit results. Contract partners have real-time access to manufacturing records and process changes affecting their purchased batches. We don’t believe in hiding behind NDAs when it comes to technical quality—our customers see as much of our data as our own staff.

    This approach isn’t just about meeting audit checklists. We keep our process charted, changes logged, every deviation documented and explained. Our systems are built for traceability down to the raw material container, so in the rare event of an issue, nothing gets left to guesswork or blame-shifting. Customers trust us because the records show where the work gets done and how decisions came about.

    Meeting the Real Requirements of Industry

    Animal protein producers and specialty compounders expect more than a single specification or certificate. They need support for shifting regulatory demands, emerging nutritional guidelines for major livestock sectors, and process changes brought by equipment upgrades in their own plants. We adjust D-Methioninol recommendations to each operating environment, gathering feedback and updating our technical support notes through real-world problem-solving.

    With new pressures on feed conversion ratios, protein yield, and residue monitoring, the bar moves higher each year. Our product meets public and private analytical scrutiny and proves itself under both lab and large-scale trial conditions. Instead of running blind to market shifts or regulatory demands, our technical and sales team work with front-line field experts to spot the next challenge before it appears.

    Building Trust Across Generations

    Generations of chemists and plant managers have made their mark on our process, building a culture that values technical honesty and practical experience over PR claims. This attitude shows through in every aspect of D-Methioninol production. When a customer’s operation meets a new challenge—like shifting feed regulations, an unexplained drop in plant efficiency, or a sudden need for even tighter purity—a direct line opens to the right expert, whether in the QC lab or the manufacturing suite. Over time, this reputation for responsibility and openness has brought more business than any short-term marketing claim ever could.

    Through continual investment, honest feedback, and reliance on proven hands, we make D-Methioninol not just a product, but a lasting partnership with the industries we serve. Actual results underpin every specification; actual use stories shape our progress. That’s the foundation of the trust this product enjoys in factories, feed mills, and laboratories across continents.