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HS Code |
458475 |
| Name | D-(+)-Camphoric Acid |
| Synonyms | 1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid |
| Chemical Formula | C10H16O4 |
| Molar Mass | 200.23 g/mol |
| Cas Number | 552-30-7 |
| Appearance | White crystalline powder |
| Melting Point | 186-188 °C |
| Solubility In Water | Slightly soluble |
| Optical Rotation | [α]D20 +47° (c=1, H2O) |
| Boiling Point | Decomposes before boiling |
| Density | 1.29 g/cm³ (approximate) |
| Pka | 2.37, 4.75 (carboxylic acid groups) |
As an accredited D-(+)-Camphoric Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 100g D-(+)-Camphoric Acid is packaged in a sealed amber glass bottle with a secure screw cap and chemical labeling. |
| Shipping | D-(+)-Camphoric Acid is typically shipped in tightly sealed containers to prevent moisture absorption and contamination. It is packed in compliance with chemical safety regulations, often in polyethylene-lined drums or bottles. The shipment is labeled with hazard information, and documents detail proper handling, storage, and emergency procedures. |
| Storage | D-(+)-Camphoric Acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of heat and ignition. Protect it from moisture and incompatible substances, such as strong oxidizers. Keep it out of direct sunlight, and store at room temperature. Ensure proper labeling and follow relevant chemical storage guidelines for safe handling. |
Applications of D-(+)-Camphoric Acid in Industrial ManufacturingD-(+)-Camphoric Acid serves as a functional intermediate in distinct chemical sectors, supporting specialty synthesis pathways and targeted product development. We manufacture precise, specification-controlled grade material for consistent integration into demanding downstream processes. 1. Specialty Polyimide Resin Synthesis for High-Temperature FilmsProducers of advanced polyimide films select our camphoric acid as a dianhydride chain modifier. Molecular rigidity enhances thermal stability and insulative performance in thin dielectric laminates. Polyimide manufacturers incorporate this compound at the imidization stage for enhanced glass transition temperature (Tg) and flexibility balance, essential in aerospace and electronic insulation films. Industry compliance standards
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2. Asymmetric Synthesis of Chiral Pharmaceutical IntermediatesAPIs and intermediate synthesis plants utilize this chiral acid as a resolving agent or a stereochemical auxiliary in asymmetric hydrogenation and aldol reactions. The rigid bicyclic structure introduces enantioselectivity during formation of target stereocenters, implemented under cGMP reactor conditions for regulated intermediate substances. Industry compliance standards
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3. Curing Agent in Crosslinked Epoxy Resins for Structural CompositesEpoxy system manufacturers add camphoric acid as an aliphatic diacid curing agent for developing specialty crosslink densities. The use of this acid imparts specific glass transition and mechanical property profiles, particularly in lightweight composite panels and adhesives designed for transportation and industrial tooling sectors. Industry compliance standards
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4. Fine Perfume Ingredient for Fragrance and Flavor FormulationFlavour and fragrance compounders incorporate camphoric acid as a mild, woody odorant and aroma fixative. It is applied in luxury perfumery to stabilize volatile terpenes and augment the fixative base of colognes. In flavor compositions, blenders employ this acid for herbal and minty top-notes with controlled regulatory compliance in food-contact applications. Industry compliance standards
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5. Metal Surface Passivation Agent in Electroplating SolutionsElectroplating solution manufacturers use this diacid as a crystal habit modifier and passivator for non-ferrous metal finishing, especially zinc, nickel, and copper baths. The controlled introduction of camphoric acid suppresses dendritic growth, refines grain size, and mitigates pinhole formation in electrodeposited metal layers, critical for electronics and decorative hardware manufacturers. Industry compliance standards
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6. Modifier for Alkyd Resin Production in Industrial CoatingsAlkyd resin manufacturers integrate camphoric acid to adjust the acid value and branching in the polyester backbone. The bicyclic structure endows the final resin with superior weather resistance and scratch hardness, supporting long-lifetime industrial coatings for metal and wood substrates exposed to demanding environmental conditions. Industry compliance standards
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In the crowded world of specialty organics, D-(+)-Camphoric Acid stands apart for the practical performance it offers. Our experience manufacturing this compound, model 124-83-4, has brought us face-to-face with the small details that make or break a process. Chemists reach for D-(+)-Camphoric Acid because they value consistency in enantiomeric purity, strong chiral control, and a clean profile that keeps impurities from becoming someone else's problem downstream.
Production lines and research benches both rely on clarity and predictability. Our D-(+)-Camphoric Acid is shaped through enantioselective synthesis, followed by repeated crystallizations until we hit an optically pure product each batch. We take repeated samples throughout the run, not just at the end—missing one off-note in the process costs more than a day of production. We’ve learned over years of manufacturing that you cannot fix a process by slapping on a certificate at the end. The true point of difference comes from hard choices on raw material selection, regular calibration checks on chiral HPLC, and constant eyes on moisture content. The result: no hidden surprises for our partners working in pharmaceuticals, flavors, or custom synthesis.
With a melting point near 187°C, D-(+)-Camphoric Acid shows a solid, dry profile at room temperature, lending itself well to sealed storage and stable handling. Bulk density sits around 1.68 g/cm³. The molecular formula, C10H16O4, gives this acid a reliable backbone for further derivatizations or salt formations. Chiral purity regularly exceeds 99.5% ee in our final product, verified by both polarimetry and chromatographic techniques. Each drum ships with clear lot-level data to help our customers link results back to every step of the chain. No need for speculation: we back every shipment with records of every test performed, every stage of the process.
D-(+)-Camphoric Acid carries weight in chemical manufacturing because of its unique structure: a bicyclic, rigid skeleton built from the natural camphor framework. This ring system resists unwanted reductions or rearrangements under common reaction conditions, which matters for makers of chiral ligands, pharmaceutical intermediates, and flavor molecules. Unlike the racemic or L-forms found in some markets, our D-(+)-Camphoric Acid delivers a single, defined stereochemistry—critical for synthesis routes where even slight shifts in optical purity can disrupt downstream properties or regulatory filings.
Over the years, companies have brought us into their process troubleshooting on projects where D-(+)-Camphoric Acid forms the launch point for active pharmaceutical ingredients or specialty additives. Each time, the issues boil down to details that get missed on spec sheets: what trace acetic acid does to a catalyst, or how the powder’s particle size distribution affects slurry flow in rotating reactors. We’ve even seen differences in residual water content throw off the formation of camphorate salts in advanced materials projects. Routine hands-on collaboration with formulators lets us anticipate these needs and adjust grind profiles, dryness, and packaging formats to match.
Working with flavor houses, the material must remain pure—any foreign odor would disrupt the carefully balanced end notes of natural essences. So, our team reviews headspace GC regularly, not just for regulatory compliance, but to prevent flavor shifts customers might not notice until production milestones have slipped. The rigidity of camphoric acid's backbone lets it stabilize volatile blends, especially those featuring menthol, camphor, or boron derivatives. No drop-in replacements preserve this same chiral structure with the stability and purity needed for sensitive flavor and aroma synthesis.
For those tuning chiral catalysts or modifying polymers, the D-(+)-enantiomer forms part of a progression of ligands and cross-linkers otherwise impossible to create. Where the racemic or L-form would scramble the final product’s configuration, this material gives a single-handed base for every new molecule. We take pride in building out that asymmetry cleanly and reproducibly, batch after batch, because so many researchers have added “unknowns” to their list of worries after trying cheaper alternatives.
Manufacturers know: not all camphoric acids are born equal. The D-(+)-enantiomer distinguishes itself from the L-form not just by arrangement of atoms, but by regulatory acceptance, application fit, and the chemistry each supports. Pharmaceutical companies and academic researchers often reach out after running into snags with material from other sources—issues ranging from milky solutions in solvent to optically impure streams that can’t pass their own in-process controls. Our team stays active in sharing methods for confirming identity: from NMR fingerprints to circular dichroism, we help chemists get to the root of any discrepancies without guessing games.
Similar compounds like racemic camphoric acid might look interchangeable in a catalog, but using them for synthesis means risking product liability in pharma or food. Those trying to swap one for the other risk odd crystallization, unpredictable reactivity, or problems during scale-up. We’ve made it our goal to supply a product that brings confidence, even in large production lots, and to engage directly with scale-up teams on every question or process change, right down to advising on solvent mixing or filter design.
No amount of marketing makes up for an unexpected impurity that turns up late in the game, especially in chiral chemistry. That’s why our manufacturing focus leans on analytical transparency. We regularly invest in high-resolution NMR, mass spectrometry, and chiral chromatography, not as afterthoughts, but as tools for continuous improvement. Every procedural change—be it in crystallization solvent, drying approach, or packaging material—runs through a battery of test cycles in our QC labs before ever shifting standard operating procedure.
Some of our longest-term customers started out searching for a material that wouldn’t clog filters or gum up reactors during isolation steps. A steady stream of feedback from their plant chemists led us to modulate crystal habits and drying approaches, shifting away from fast precipitation toward methods that yield more spherical, easy-to-wash particles. Small refinements in handling and scale have saved everyone headaches and kept downtime to a minimum. Lab-based scientists have different concerns, so we supply options for jar pack-outs and vial sizes, packaged with reliability in mind.
The world is moving away from legacy solvents and high-waste synthesis methods. Manufacturing D-(+)-Camphoric Acid means facing the reality of waste minimization, solvent selection, and process energy use. Rather than push superficial marketing on “green” credentials, we track every waste stream by mass and energy use by the hour. Our recent process evaluation let us recover and recycle solvent for more than 60% of our runs each year, while pressure filtration improved overall throughput and cut both process water and energy costs.
Any synthesis based on petrochemicals, like camphor, brings up real questions about renewability and traceability. Over the past decade, we have partnered with suppliers to switch nearly all raw camphor sourcing toward plantations using sustainable forestry practices, creating audit trails that match regulatory requirements worldwide. This traceability matters to our customers shipping specialty food or pharma grade intermediates to Japan, North America, or Europe, where regulatory bodies turn a critical eye to every kilogram of input.
Waste acid neutralization, pigment removal, and atmospheric emissions get monitored batch by batch, not just for legal compliance but to avoid the headaches of cleanup down the road. Our plant teams deal with these issues in real time, adjusting process controls in response to evolving environmental goalposts. That approach keeps us nimble, able to react to customer challenges and new requirements as they show up—no hiding behind outdated paperwork.
Making D-(+)-Camphoric Acid at scale is not just about technical precision. Each end-use brings a set of requirements that keep us on our toes. In the pharmaceutical sector, GMP-adjacent protocols, full data transparency, and rapid response to any deviation in lot profile matter more than anything else. Chemistry doesn’t let us cut corners: batches that fall short get held back before they ever leave the warehouse.
For flavor manufacturers, ultra-low odor lets the camphoric acid act as a backbone for complex notes, while food safety requires clear documentation for trace metals, solvents, and by-products. Our QA team checks every outgoing shipment for these trace implications, knowing that a trace off-odor or unidentified peak triggers questions at the customer’s end. We fit each supply with a digital profile—chromatograms, MS spectra, and traceability data—for direct review by either purchasing or quality teams. That earned trust from our best customers didn’t come overnight. Consistent delivery, clear record-keeping, and real support for their teams create the real edge.
Advanced materials research throws even more curveballs: thermal stability, compatibility with dopants, and granular batch reporting. Not every producer handles these edge-case requests. We built out custom documentation and flexible fulfillment to help novel researchers keep pace, even as their projects touch on hydrogen storage, smart polymers, or next-generation battery components.
No trader or catalog house can answer technical questions the way a manufacturer with direct process ownership can. We hear from customers who hit stumbling blocks with resellers or faced months-long lead times over quality disputes. Our plant chemists and R&D team respond directly to questions—whether it’s about nuanced solubility with new solvents, unknown elution times, or cross-contamination risks during scale-up. Because we control every step, from incoming raw camphor to outbound loading dock, our answers ring true and actionable.
We make it a point to run side-by-side process demonstrations or custom test runs for partners scaling up new projects. This approach moves the conversation from abstract specs to real-world solutions. It’s easy to talk about “support” in neutral terms — but for us, it means getting on the phone, setting up remote QA walks, or even shipping out split batch samples for cross-checking with customer labs. The result: more transparent problem-solving, less idle speculation.
Chiral chemistry and stringent regulatory frameworks show no sign of easing up. Today’s buyers of D-(+)-Camphoric Acid, especially those in pharma and food, face stricter requirements for documentation, impurity profiling, and sustainable practice. We watch these regulations, anticipate next steps, and invest ahead of mandates—so our customers can focus on their end products, not compliance headaches. We are seeing more demand for supporting data packages: from advanced optical rotation benchmarks to expanded solvent-residual panels, right down to scans for micro impurities at single-digit ppm levels. Our lab pushes each batch to clear these hurdles before they become customer-facing bottlenecks.
Where possible, we keep a feedback loop open to users bringing up edge-case requirements—like new isomeric forms or innovative salt formations for materials use. In many instances, this kind of fluid, real-time dialog saves customers time and keeps their R&D on track. Our approach favors direct communication and process flexibility, not just to win orders but to genuinely shorten lead times and raise confidence levels industry-wide.
As direct chemical manufacturers, we see the inside of every kettle, the dust in every barrel, and the oddities that never make it into standard product descriptions. That’s the knowledge customers call on when they choose D-(+)-Camphoric Acid for their critical builds. We steer clear of templated claims or fill-in-the-blank certifications; instead, our team shows up with real numbers, hands-on manufacturing insight, and an open book on every process variable from start to finish.
Choosing D-(+)-Camphoric Acid from a direct producer means getting past buzzwords and sales gloss: it’s about reliability, a predictable profile every shipment, and an open line for the tough questions as well as the routine orders. In an industry built on precision and timing, that experience is worth its weight in gold.