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Cyclopropylbenzene

    • Product Name Cyclopropylbenzene
    • Alias Benzene, cyclopropyl-
    • Einecs 202-845-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    233835

    Chemical Name Cyclopropylbenzene
    Molecular Formula C9H10
    Molar Mass 118.18 g/mol
    Cas Number 872-50-4
    Appearance Colorless liquid
    Boiling Point 172-174 °C
    Melting Point -46 °C
    Density 0.96 g/cm³
    Refractive Index 1.514
    Flash Point 51 °C
    Solubility In Water Insoluble
    Odor Aromatic
    Structure Benzene ring with a cyclopropyl substituent
    Storage Conditions Store in a cool, dry, well-ventilated place
    Pubchem Cid 6962

    As an accredited Cyclopropylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cyclopropylbenzene, 500 mL, is packaged in an amber glass bottle with a secure screw cap and hazard labeling for safety.
    Shipping Cyclopropylbenzene is typically shipped in tightly sealed containers to prevent leaks and volatilization. It should be transported in accordance with local regulations for flammable organic liquids, away from heat, sparks, and incompatible materials. Proper labeling and documentation are required. Protective measures are recommended to minimize exposure during handling and transport.
    Storage Cyclopropylbenzene should be stored in a cool, dry, well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and properly labeled. Store away from strong oxidizers, acids, and bases. Ensure appropriate spill containment and use compatible, chemical-resistant containers. Follow all relevant safety regulations and ensure access to emergency equipment such as eyewash stations.
    Application of Cyclopropylbenzene

    Applications of Cyclopropylbenzene in Industrial Manufacturing

    As a dedicated chemical raw material manufacturer, we supply Cyclopropylbenzene tailored to real-world industrial synthesis networks. Its unique chemical structure and reactivity enable downstream producers to develop and scale essential intermediates for advanced chemicals, polymers, and performance materials. Below are key application sectors where our product delivers critical value through established processing routes and strict compliance frameworks.

    1. Pharmaceutical Intermediate Synthesis

    Cyclopropylbenzene serves as a key aryl cyclopropane building block in the formation of active pharmaceutical ingredient (API) intermediates, particularly for compounds where cyclopropyl moieties impact target receptor activity. Manufacturers use it in Grignard coupling and Friedel–Crafts alkylation steps, with downstream hydrogenation or halogenation. Our cyclopropylbenzene meets traceability and impurity requirements for regulated API precursor synthesis, feeding into controlled small- and large-scale batch lines where quality consistency remains crucial to regulatory and pharmacopoeia submissions for final clinical products.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • EU GMP Part II (APIs)
    • USP-NF and EP monographs for intermediates (where applicable)

    Typical usage ratio

    • 5–20% w/w in reaction mass, with exact proportion dependent on API intermediate yield targets and stoichiometric demands determined by downstream synthesis route

    Downstream process integration

    • Introduced post-aromatic halogen exchange or boronic acid formation, followed by catalytic coupling and, when required, protection/deprotection manipulations prior to API assembly

    Final product types

    • Active pharmaceutical ingredients (e.g., for antivirals, CNS agents)
    • Advanced intermediate compounds for generic and specialty drugs
    • Pilot-scale research chemicals for new molecular entities (NMEs)

    2. Agrochemical Intermediate Manufacturing

    Downstream agrochemical formulators utilize cyclopropylbenzene as a precursor for cyclopropyl-substituted aromatic intermediates, which are subsequently transformed into active substances in herbicides, insecticides, and fungicides. Its aromatic core and cyclopropane ring impart essential chemical stability and selectivity traits in agroactive molecules. Supply and production lines meet international standards for environmental safety, operator health, and trace residue control during field application.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 for agrochemical manufacturing
    • REACH Regulation (EC) No 1907/2006 for chemical safety

    Typical usage ratio

    • 10–30% in formulated intermediate blend, fine-tuned based on final product molar requirements and downstream catalytic process efficiency

    Downstream process integration

    • Fed into aromatic substitution or oxidative cyclopropane ring-opening protocols, before introduction of bioactive side groups via nitration, sulfonation, or esterification

    Final product types

    • Herbicide actives (e.g., cyclopropyl-aniline derivatives)
    • Pyridine-based insecticide intermediates
    • Crop protection fungicide compounds incorporating cyclopropane motifs

    3. Specialty Polymer Monomer Production

    Polymer producers incorporate cyclopropylbenzene during the custom synthesis of cyclopropyl-functionalized styrenic and acrylic monomers, supporting advanced plastic resins with superior mechanical and chemical-resistance properties. The cyclopropyl group modifies glass transition temperature and impacts final polymer performance in demanding engineering and electronics settings. Our high-purity feedstock supports catalytic copolymerization and anionic or controlled radical processes, meeting downstream manufacturer’s quality audits for reproducibility and batch traceability.

    Industry compliance standards

    • ISO 9001:2015 for specialty polymers
    • RoHS Directive 2011/65/EU for electronics-related polymers
    • UL 94 Flame Classification for polymer end products

    Typical usage ratio

    • 3–15% of monomer feed, based on target copolymer composition and required functional group density, determined externally by desired polymer attributes

    Downstream process integration

    • Participates in the pre-polymerization stage via solution or emulsion polymerization methods; introduced prior to chain initiation and propagation reactions

    Final product types

    • Engineering plastics for automotive and aerospace
    • High-performance electronic encapsulants
    • Specialty acrylic resins used in adhesives and advanced coatings

    4. Fragrance and Aroma Compound Precursor

    Fragrance compound manufacturers deploy cyclopropylbenzene in the synthesis of aromatic ingredients that form the basis of musky or woody olfactory notes. Chemical transformation via oxidation, halogenation, or side-chain modifications produces structures used in fine fragrances and consumer product scents. Our quality regime ensures minimized trace contaminants and meets IFRA guidelines, which are mandatory for international fragrance supply chains and new blend development approvals.

    Industry compliance standards

    • IFRA (International Fragrance Association) Standards for ingredient safety
    • EU Cosmetics Regulation (EC) No 1223/2009 for olfactory ingredients in fragrances
    • ISO 9235 for aromatic raw materials

    Typical usage ratio

    • 2–8% relative to total precursor substances; precise ratio defined by target transformation route (oxidative versus reductive pathways) and required intensity of finished aroma

    Downstream process integration

    • Input in initial aroma precursor synthesis, typically followed by selective oxidation, esterification, or Diels–Alder reactions to generate specific perfumery chemicals

    Final product types

    • Fine fragrance compounds for perfumery houses
    • Aromatic ingredients for soap and body care
    • Flavor agents with characteristic cyclopropyl-aromatic structure for food-compatible fragrance blends

    5. Liquid Crystal Material Intermediate Production

    Manufacturers in advanced display and electronics industries utilize cyclopropylbenzene as a functional precursor for synthesizing mesogenic compounds. Its rigid aromatic nucleus and conformationally restricted cyclopropyl ring allow precise tuning of dielectric properties and nematic phase behavior in downstream liquid crystal formulation. Our controlled process chemistry supports the high-purity required for such applications, while documentation ensures electrical property performance validation as part of integrated supply to LCD and OLED component producers.

    Industry compliance standards

    • IEC 61249-2-40 for materials used in electronics
    • ISO 9001:2015 for advanced material processing
    • RoHS Directive 2011/65/EU for display component materials

    Typical usage ratio

    • 5–12% in precursor batch mix, dependent on mesogenic molecular design and electro-optic transmission requirements specified by the client’s proprietary mixture

    Downstream process integration

    • Used as a starting material in alkylation or halogenation steps, prior to final assembly of mesogen core units in liquid crystal batch synthesis

    Final product types

    • Mesogenic intermediates for nematic and smectic liquid crystals
    • Prepolymers for liquid crystal alignment layers
    • Downstream liquid crystal display materials used in panels and optical shutters
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    Certification & Compliance
    More Introduction

    Cyclopropylbenzene: Insights From the Manufacturer’s Line

    Experience Working With Cyclopropylbenzene

    Cyclopropylbenzene presents a strong case for attention and respect in our manufacturing facility. Direct hands-on production with this compound teaches the team a lot about the nuances of aromatic hydrocarbons fused with a cyclopropyl group. Factories build a lasting familiarity with its colorless, clear liquid appearance—a reassuring sign that distillation ran correctly. These flashes of clarity aren’t just visual, they’re part of a real trust built on batch after batch of consistent output. This is not something only found in books; it comes from working with the reactors, calibrating analytical equipment, and fine-tuning separations day in and day out.

    Our main run model delivers Cyclopropylbenzene at a minimum purity of 99%, supplied in steel drums or high-integrity fluorinated containers. Rigorous gas chromatography verifies every batch. Those little details—the retention time peaks, the sharp cutoff for water, and trace impurities—make the product reliable for both lab and scale-up work. Over years of manufacturing, it becomes clear that every deviation from this narrow window counts, so we don’t play fast and loose with purity or handling.

    Defining the Material: Identity and Specifications From the Plant Floor

    Cyclopropylbenzene counts as an aromatic hydrocarbon carrying a cyclopropyl ring on the benzene nucleus. Chemically, it’s C9H10, with a molecular weight just under 118. Spectroscopy gives a sharp set of signals—aromatic protons separate cleanly from the cyclopropyl stretch, so you can check the fingerprint against known spectra with confidence. On a practical level, the boiling point sits near 171°C on our calibrated columns. Its density hovers at 0.93 g/cm³ at ambient, so it flows smoothly in transfer lines but still requires vapor management and careful ventilation when pumping.

    Stability presents as another advantage. Once produced, the compound resists unwanted side reactions under reasonable conditions. Its chemical robustness helps downstream users focus on the transformation at hand—whether that means planning a Friedel-Crafts reaction, researching new pharmaceutical cores, or plugging the building block into agrochemical intermediates.

    Purpose in the Real World: Handling and Usage From First to Last Drum

    Few things create more frustration than raw material inconsistency in an active manufacturing line. Cyclopropylbenzene gets chosen by synthesis engineers who want predictable inputs and defined reactivity. In custom manufacturing contracts and tolling operations, our material enters as an intermediate for both industrial and laboratory-scale chemistry. Teams who design new compounds use cyclopropylbenzene to introduce ring strain into aromatic systems, aiming for unique molecular scaffolds impossible to achieve through straight-chain alkyl benzenes.

    It often appears as a critical ingredient in the synthesis of medicinal agents and advanced agrochemicals. Cyclopropylbenzene’s unique three-carbon ring delivers conformational rigidity. It alters the metabolic stability and physical properties of downstream molecules, which opens doors not available through other phenylalkanes. Because we manufacture from premium benzene and proprietary cyclopropanation, side products and contaminants get driven down below detectable limits.

    Comparing With Other Alkylbenzenes—Direct Observations From the Process Line

    Spend enough time around the chemical plant, and differences between cyclopropyl derivatives and ordinary alkylbenzenes become obvious. Linear analogs like ethylbenzene or n-propylbenzene flow similarly and work in some of the same transformations but don’t deliver the same reactivity. The cyclopropyl ring introduces both ring strain and a compact shape—properties that change everything from SN2 attack probability to oxidative stability. Colleagues in research and scale-up consistently report that cyclopropylbenzene resists overoxidation far better than its saturated counterparts, providing greater leeway in catalytic and radical-based transformations.

    Cost profiles also differ. Manufacturing cyclopropylbenzene takes more care and technical expertise than straight-chain benzenes. The cyclopropanation step is sensitive, demanding tighter temperature control and clean reaction conditions. Months spent tightening up process windows and improving catalytic efficiencies in plant reactors translate into the ability to consistently deliver high-purity product without off-spec batches clogging up downstream customers. This reliability sets cyclopropylbenzene apart from the crowd, especially for high-impact discovery chemistry and pilot plant operations.

    Quality Assurance: Evidence and Practice on the Ground

    Quality isn’t an accident in this field—it’s a deliberate, repetitive discipline. Every drum, tote, and bottle of cyclopropylbenzene gets checked by both classic and instrument-based methods. Visual clarity, refractive index, water content (by Karl Fischer), and residual solvent analysis give a multidimensional picture before product release. For example, trace analysis for isopropylbenzene, methylcyclopropylbenzene, and cyclopropane impurities features heavily in our certifications; small mistakes in distillation or feedstock feed-throughs leave distinct analytical signatures.

    Our in-house analytical group collaborates with production daily. Each feedstock and finished batch goes through robust retention sample archiving—critical if any customer query arises weeks or months after shipment. This database of chromatograms, NMR spectra, and historic batch records builds real trust with our partners. We see patterns forming around emerging trace contaminants, adjust the plant’s distillation columns, and address root causes before end product quality can be affected.

    Supply Realities and Handling Expectations From the Factory

    Nothing stings a manufacturer more than a preventable transport or storage problem. Cyclopropylbenzene arrives and departs in DOT-rated drums and pressure-sealed bulk containers. Internal audits of transport and warehousing systems, plus regular retraining on liquid transfer procedures, keep the team sharp on best practices. On-site, trained operators always observe vapor and spill control protocols, and batch sheets spell out every step. These details carry real weight when the plant clears high-value shipments bound for time-critical customer deadlines.

    We always push for tighter controls—down to drum labeling, odor threshold checks, and vapor containment during hot weather. Our plant has firsthand experience dealing with vapor-phase hazards: cyclopropylbenzene is flammable and demands respect during transfer and unloading. We provide material safety training for every new technician, with refresher drills simulating drum leaks and fire scenarios. This hands-on commitment has dramatically reduced incidents over the past decade, far more so than any paper compliance ever could.

    Regulatory Points and Environmental Perspective—From Factory Gate to Final Application

    Regulatory guidelines build a living framework for the entire supply chain, not just for show. We keep up with evolving rules on aromatic hydrocarbon emissions, storage conditions, and batch traceability. Facility managers coordinate quarterly with local authorities to review emissions reporting and waste stream documentation. Cyclopropylbenzene itself doesn’t fall under every high profile restriction, but its class sits under watch in some regulatory regimes. The team manages all raw material sourcing and generation tracking under ISO and local statutory standards. Spills, leaks, or noncompliance matter for more than paperwork—they impact reputation and local relationships.

    Waste minimization and solvent recycling programs at our plant sprang out of first-hand experience with process loss and disposal cost. Cyclopropylbenzene’s volatility means even small operational errors can drive up emissions and waste. Process engineers developed closed-loop systems for residue collection, vapor condensation, and distillation cut recovery. Not only did these investments cut disposal volumes, but they also improved cost per unit—putting us ahead of outdated, open-system competitors still losing product to the atmosphere or off-site incineration.

    Innovation and Problem-Solving—Feedback Loops from the Manufacturing Hull

    Process improvement sits at the core of the plant’s daily workflow. Teams meet weekly to flag issues—drum deformation, unexplained haze, shipment delays—and dig out solutions. These aren’t theoretical discussions; they draw on batch logs, shift handover notes, and customer follow-ups. Recently, our staff introduced in-line optical sensors to catch micro-impurities before the final polish column. The move cut batch rejects in the specialty products line and improved downstream customer yield by a measurable five percent.

    Customers pushing into new synthetic territory often request deeper technical support and real-time process adjustments. We facilitate telephone triage or video walk-arounds in the bulk storage yard to solve problems fast. If a research group discovers an unforeseen impurity profile appearing in high-throughput screening, our production chemists collaborate on sourcing, analytical, and process adjustments directly—sharing chromatograms and field notes in real-time, not just sending generic certificates.

    Customer Knowledge—Speaking From Years in the Chemical Trenches

    Over the years, our best customers are usually the ones who collaborate openly and ask questions early. Headline specs capture much, but experienced chemists often seek deeper understanding: what’s the typical impurity pattern, what does a storage-induced isomerization look like, how much handling does it tolerate before purity drifts? Our technical staff has seen most scenarios—just ask and there’s likely a story or a lesson learned.

    We’ve watched cyclopropylbenzene become a key starting point for introducing rigid, compact building blocks into new medicinal scaffolds. What’s unique compared to toluene, ethylbenzene, or simple propyl analogs is the way the cyclopropyl ring maintains its integrity under aggressive synthetic conditions. Several customers in the crop-protection industry reported that pilot reactions using our cyclopropylbenzene held up better against strong oxidizers and metal catalysts. These sorts of user-led validation stories, running alongside our own QA efforts, shape the ongoing development of our process and support infrastructure.

    Looking Ahead—Continuous Progress at the Manufacturing Level

    Real-world chemical manufacturing doesn’t stand still. Each production year brings new efficiency targets, upgraded analytical instruments, and broader regulatory expectations. For cyclopropylbenzene, scalability and purity enhancement lead our improvement agenda. Small, incremental reactor upgrades—better feed control valves, automated impurity bleeding, tighter distillation cut points—incrementally raise output quality. Unlike tradable commodities, every nuance of cyclopropylbenzene’s physical and chemical profile matters for downstream applications where side reactions can cost labs and plants significant time and material waste.

    We invest heavily in plant personnel training and safety programs—not just for regulatory compliance, but to foster pride in doing the job right. A well-trained operator knows the subtle shift in pump sound that signals a developing leak, or the telltale drop in refractive index that means a contaminant just slipped through. These aren’t skills picked up in a classroom; they’re carved out of thousands of production hours and hard-won experience troubleshooting real plant challenges.

    Distinctive Strengths and Persistent Challenges—The Day-to-Day Viewpoint

    Cyclopropylbenzene stands out as a versatile intermediate, yet its very versatility makes precision and vigilance indispensable. With each change in customer application or regulatory requirement, we evaluate process fit and product profile internally before agreeing to supply new grades or specifications. Supply chain disruptions—feedstock price volatility, logistics bottlenecks, or even unforeseen geopolitical events—bring lessons. Flexibility and rapid problem-solving matter just as much as technical prowess, especially for specialty batch orders where downtime or an off-spec shipment has cascading effects on partners up and down the value chain.

    Equipment reliability, trusted logistics partners, and qualified analytical support keep shipments on track. There’s little room for bureaucratic formality or hands-off, third-party thinking in this business. It’s relentless attention to detail and respect for the container on the factory floor—treating every kilogram as part of a bigger story. The people making and handling cyclopropylbenzene every day know that their efforts contribute directly to the success stories of customers discovering the next generation of molecules in research, manufacturing, and application development.

    The Unique Place of Cyclopropylbenzene on the Modern Chemical Landscape

    Working day after day with cyclopropylbenzene, the differences reveal themselves both in the lab notebook and in the plant log. What appears at first as a niche aromatic hydrocarbon wins its place through steady performance, predictable reactivity, and adaptability in advanced chemical synthesis programs. In our experience, it remains irreplaceable for those aiming to combine aromatic stability with the synthetic freshness of a three-membered ring. Manufacturing the compound—a process built from a blend of deep chemical knowledge, hands-on skill, and relentless fine-tuning—becomes a source of both professional pride and practical value for all involved.