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HS Code |
502723 |
| Product Name | Cyclopropanecarboxylic Acid Hydrazide |
| Cas Number | 4441-22-3 |
| Molecular Formula | C4H8N2O |
| Molecular Weight | 100.12 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 83-87°C |
| Solubility | Soluble in water |
| Purity | Typically ≥98% |
| Storage | Store in a cool, dry place |
| Synonyms | Cyclopropanecarbohydrazide |
| Smiles | C1CC1C(=O)NN |
| Inchikey | WXXFZZPOPFLSRX-UHFFFAOYSA-N |
| Hazard Statements | May cause irritation to skin, eyes, and respiratory tract |
As an accredited Cyclopropanecarboxylic Acid Hydrazide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Cyclopropanecarboxylic Acid Hydrazide, 25 grams, is packaged in a sealed amber glass bottle with a secure screw cap. |
| Shipping | Cyclopropanecarboxylic Acid Hydrazide should be shipped in tightly sealed containers, protected from light and moisture. Transport as a stable solid at ambient temperature unless otherwise specified. Ensure compliance with local, national, and international regulations for chemical shipping, and label as a laboratory chemical with appropriate hazard warnings if required. |
| Storage | Cyclopropanecarboxylic Acid Hydrazide should be stored in a tightly closed container, in a cool, dry, and well-ventilated area. Protect from direct sunlight, moisture, and sources of ignition. Store away from incompatible substances such as oxidizing agents and acids. Ensure proper labeling and secure storage to prevent unauthorized access. Recommended storage temperature is typically room temperature (20-25°C), unless otherwise specified by the manufacturer. |
Applications of Cyclopropanecarboxylic Acid Hydrazide in Industrial ManufacturingCyclopropanecarboxylic Acid Hydrazide serves as a specialized intermediate in multiple advanced chemical sectors. Our facility supplies this raw material for integration into precise downstream formulations requiring high purity and batch consistency. Below, we detail proven application scenarios according to market feedback and regulatory standards. 1. Agrochemical Synthesis: Herbicide Active Ingredient ProductionAgrochemical companies deploy cyclopropanecarboxylic acid hydrazide for the synthesis of heterocyclic intermediates used in selective herbicide actives. Its unique cyclopropyl backbone enhances the performance of hydrazide-based block-building reactions during the generation of triazole and pyrazole frameworks found in modern formulations. Commercial production requires strict management of residual hydrazide via validated analytical protocols. Our technical support covers compatibility and real-time monitoring in continuous or batchwise systems deployed by major crop science manufacturers. Industry compliance standards
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2. Pharmaceutical Intermediates: API Building Blocks for CNS Drug SynthesisRegulated pharmaceutical manufacturers use cyclopropanecarboxylic acid hydrazide as a core intermediate in the assembly of API skeletons targeting central nervous system disorders. Its incorporation occurs at hydrazine exchange steps for the introduction of constrained ring substituents, which modulate pharmacokinetic and physiochemical properties. Process development involves validated impurity control protocols and robust traceability from raw material intake to final API crystallization batch. Our supply chain supports GMP-grade material and custom specification adjustment to comply with multi-market registration demands. Industry compliance standards
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3. Veterinary Drug Intermediate ManufacturingAnimal health sector manufacturers utilize cyclopropanecarboxylic acid hydrazide in the controlled synthesis of hydrazide-containing active substances for veterinary medications. The molecule’s constrained ring assists in the development of reduced toxicity and improved delivery characteristics in parasite control agents. Our technical documentation supports full traceability and customized impurity reporting for export-oriented veterinary plants. Material is delivered with COA covering impurity fingerprint, solubility, and IR spectrum on batch-by-batch basis. Industry compliance standards
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4. Chemical Research & Analytical Reference StandardsAnalytical laboratories, specialty chemical institutes, and quality control centers procure cyclopropanecarboxylic acid hydrazide for developing calibration curves and as a reaction marker in structure–activity relationship (SAR) research. It is utilized in method development for chromatography assays checking for hydrazide group reactivity, stability, and detection limits. Our product comes with batch-specific full spectrum and C of A supporting traceable chain for certified reference material registration or custom blending projects under documented quality practices. Industry compliance standards
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Our experience as a longstanding producer of specialty fine chemicals gives us a clear view of what our clients look for in chemicals like Cyclopropanecarboxylic Acid Hydrazide. This compound, offered under model designation CPAH-025, continues to draw attention from pharmaceutical research labs and specialty chemical formulators for its unique cyclopropyl backbone. When chemists talk about building more selective, potent, or safer compounds, the cyclopropyl motif offers rigidity that can subtly change how molecules behave. Hydrazides provide concise access to hydrazones and open additional doors for derivatization. That combination gives Cyclopropanecarboxylic Acid Hydrazide a distinct edge over standard hydrazides or open-chain analogs.
Our manufacturing starts with carefully sourced cyclopropanecarboxylic acid, steadily reacting it with hydrazine hydrate under controlled conditions. Tight temperature and pH oversight minimizes side-product formation—something less-disciplined processes often miss, which can cause headaches for those running multi-step synthesis. Time and again, customers switching to our lot report fewer purification issues downstream. Every batch leaves our facility with a certificate showing purity ≥99%, checked by NMR and HPLC. That level of quality lets medicinal chemists step straight into the next stage of their project rather than spending extra hours cleaning up avoidable impurities.
In our hands, Cyclopropanecarboxylic Acid Hydrazide comes as a fine crystalline solid, pale white, and stays stable for years under dry, ambient storage. Its melting point falls near 123–125°C, consistent with what has been published in the literature. We use sturdy, moisture-tight packaging to prevent clumping or hydrolysis during long transit—even across continents. Our QA records show less than 0.2% deviation in melting point or appearance for hundreds of production lots shipped globally.
Standard hydrazides like acetic or propionic acid hydrazide show up on lab benches, but Cyclopropanecarboxylic Acid Hydrazide carries distinct advantages. In medicinal chemistry, the cyclopropyl group often blocks metabolic oxidation, increasing a candidate compound’s half-life. It can lock side chains in spatial arrangements that boost activity or selectivity at biological targets. We have seen clients in preclinical drug discovery use our product to move past puzzles with metabolic instability or undesired isomerization.
Other hydrazides with aromatic rings or longer open chains tend to add unnecessary bulk or leave molecules exposed to oxidation. Cyclopropanecarboxylic Acid Hydrazide, with a compact ring and minimal branching, fits nicely into scaffold modification where spatial economy counts. Some agrochemical labs told us this hydrazide helped them design candidates that resisted breakdown by soil microbes better than others they tested.
Medicinal chemists prize Cyclopropanecarboxylic Acid Hydrazide because it forms reliable hydrazones—key intermediates in synthesis of heterocycles, active pharmaceutical ingredients, and imaging probes. The hydrazide function readily condenses with aldehydes or ketones, but thanks to the cyclopropyl core, the resulting products often show notable rigidity and metabolic resistance. Over the past decade, most patent applications using this intermediate trace back to lead optimization in oncology, CNS disorder therapies, and selective pesticides.
Our direct users rarely stick to textbook steps. We engage with synthetic teams using reductive amination, click-chemistry, and even electrochemical functionalization with Cyclopropanecarboxylic Acid Hydrazide as a starting block. Because our manufacturing allows scaling from gram to multi-kilogram quantities, we often support programs going from concept through to initial clinical supply without a hitch in quality or traceability.
Some compounds look fine on paper but create bottlenecks when you take them plant-scale. Poor solubility, sticky residues, batch-to-batch drift—small annoyances at gram scale can become disasters at 10 or 100 kilograms. Our R&D chemists figured out how to crystallize Cyclopropanecarboxylic Acid Hydrazide in a tightly controlled manner. We avoid discoloration, run comprehensive moisture analysis, and test for hydrazine left over in every batch. As the manufacturer, we attribute our process success to repeated, hands-on troubleshooting and careful equipment maintenance. You don’t need to worry about residues or trace metals—ICP-MS data from our QC lab shows well below ppb levels.
Producing hydrazides, particularly those involving hydrazine intermediates, requires stringent safety systems. We invested heavily in closed handling, careful pressure control, scrubbers, and employee PPE. Our records show zero incidents related to hydrazide exposure in the last five years, which few operators in this sector can claim. Once the product leaves our plant, its stability in shipment and absence of dusting reduces risk for users handling larger volumes.
For waste management, we neutralize residual hydrazine under controlled oxidation, then recycle effluents into less-hazardous forms where possible. Our plant holds ISO certifications for both safety and environmental stewardship. That gives clients extra assurance that their own ESG (environmental, social, and governance) policies will not be at odds with their starting materials. We work with local regulators and participate in regional clean-synthesis initiatives.
Clients ask us about the real difference between buying manufacturer-sourced Cyclopropanecarboxylic Acid Hydrazide versus generic material sitting with a trader. The straight answer comes down to reliability and peace of mind. As the manufacturer, we own the data, know the upstream supply chain, and issue traceable documentation. No surprise contaminants creep in from storage, transit, or repackaging steps. If a client encounters a technical hiccup, they reach our senior process chemists—not a reseller passing messages between parties.
Supply security increases with direct manufacturing. Raw material sourcing, process scalability, flexibility in packaging, and guaranteed batch repeatability stem from our hands-on approach. During global supply chain disruptions, we ramped up production on short notice, keeping crucial research programs running. Scientists’ output shouldn’t hinge on whether a reseller happens to have a dusty drum in stock, or whether some paperwork goes missing in customs. Our system builds in process documentation, regular verification, and comprehensive shipment tracking.
Labs aiming for high yields with minimal chromatographic fuss report good outcomes using our Cyclopropanecarboxylic Acid Hydrazide. The product’s high purity and reliable crystalline form speed up workups and crystallizations. We support both small-scale screening and pilot-scale manufacture with tailored lot sizes. Requests for detailed analytical data—NMR, IR, LC-MS, residual solvent profiles—draw on our in-house records, with reports available to every client.
Whenever synthesis gets tricky, like developing a new route for complex nitrogen heterocycles, our chemists collaborate with customers to optimize conditions. That includes sharing proven work-up procedures, solvents that suppress side reactions, or advice balancing temperature and reagent stoichiometry. Because our production never shifts to contract or external providers, the data matches the product in your hands.
Clients from applied pharmaceutical research, academic labs, and specialty chemical developers frequently report on the difference that manufacturer-supplied material makes in their workflow. They mention fewer repeat experiments, easier scale jumps between batches, and reduced time arguing with regulators over quality documentation. Rarely does a week go by without a request for guidance on novel uses of cyclopropyl hydrazides—in polymers, fluorescent probes, or even new battery materials. We take those queries seriously, tracking developments so we can keep improving both manufacturing and application support.
The market for fine chemicals flooded with intermediaries makes it hard for end users to separate genuine quality from generic bulk. When clients pick up our Cyclopropanecarboxylic Acid Hydrazide, they gain access to more than just a chemical. They receive deep technical background, transparent sourcing, rigorous purity traceability, and practical advice honed by decades of manufacturing and application. That difference shows itself not just in spreadsheets, but in real improvements in project timelines, experiment reproducibility, and confidence under regulatory review.
For projects headed toward clinical or commercial production, every upstream mistake grows larger farther down the pipeline. Using hydrazides sourced directly from the manufacturer gives your team a head start, reduces troubleshooting, and eliminates the quiet risk that comes from sourcing off-brand chemicals. In challenging industries, where a failed experiment or contaminated reagent means lost weeks or months, certainty gets valued above minor cost savings from anonymous sources.
Innovation happens where reliable materials, deep technical knowhow, and open feedback loops intersect. Our role as a chemical manufacturer ties together decades of process knowhow, strong supplier partnerships, and close collaboration with scientists who use Cyclopropanecarboxylic Acid Hydrazide to push boundaries. We prioritize openness. Every inquiry gets answered by someone familiar with the actual product history, every batch gets archived and cross-checked, and improvement never stops. For those in the trenches of lab and pilot plant research, that trusted foundation means less energy spent second-guessing a chemical’s backstory, and more energy finding the next big breakthrough.
Cyclopropanecarboxylic Acid Hydrazide, model CPAH-025, reflects the strengths of focused, scale-ready, and customer-driven chemical manufacturing. In our hands, this compound delivers reliability, purity, and a flexibility tailored to practical science. Each production run deepens our technical capability and builds up relationships across markets, from pharmaceuticals to specialty materials. By working directly with the manufacturer, chemists ensure every milligram shapes progress, not just protocol.