Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Cyclopentanethiol

    • Product Name Cyclopentanethiol
    • Alias Thiocyclopentane
    • Einecs 208-865-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    713546

    Cas Number 14264-16-5
    Molecular Formula C5H10S
    Molar Mass 102.20 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Strong, unpleasant, skunky odor
    Boiling Point 143-144 °C
    Melting Point -70 °C
    Density 0.942 g/mL at 25 °C
    Solubility In Water Insoluble
    Flash Point 32 °C (closed cup)
    Refractive Index 1.506 at 20 °C
    Logp Octanol Water 2.1

    As an accredited Cyclopentanethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cyclopentanethiol is packaged in a 100 mL amber glass bottle with a tightly sealed cap and hazard labeling for safe handling.
    Shipping Cyclopentanethiol is shipped in tightly sealed, chemical-resistant containers, compliant with hazardous materials regulations. Handle with care due to its flammable, volatile, and malodorous nature. Transport and storage should avoid heat, sparks, and open flames, and containers must be clearly labeled. Use appropriate safety measures and documentation during shipment.
    Storage Cyclopentanethiol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible substances such as oxidizers. Keep the storage area free from acids and bases. Ensure appropriate labeling, and protect from physical damage. Use secondary containment to prevent leaks and spills, and store separately from food and drink.
    Application of Cyclopentanethiol

    Applications of Cyclopentanethiol in Industrial Manufacturing

    Cyclopentanethiol serves as a specialty raw material in multiple industrial processing sectors requiring sulfur-functionalized intermediates. Our production adheres to stringent quality controls, making this compound suitable for highly regulated applications where chemical purity and consistent supply directly impact the performance and safety of finished goods. The following scenarios summarize the primary application pathways where customers employ cyclopentanethiol in global downstream industries.

    1. Agrochemical Synthesis: Herbicide Intermediate Manufacturing

    In the agrochemical sector, manufacturers utilize cyclopentanethiol as a precursor for synthesizing thiol-functionalized intermediates applied within sulfur-containing herbicide molecules. The unique structure enables alkylthiolation steps vital for producing certain selective post-emergent weed control agents. The raw material is directly introduced during closed-reactor alkylation reactions, followed by purification and conversion within multi-step synthetic routes, ultimately supporting robust global herbicide supply chains.

    Industry compliance standards

    • OECD Good Laboratory Practice (GLP)
    • US EPA 40 CFR Part 160 Regulations for Pesticide Data
    • European Union REACH (EC) No 1907/2006 requirements for pesticide intermediates
    • China GB 2763: Maximum Residue Limits for Pesticides in Foods (relevant for downstream

    Typical usage ratio

    • 3–8% w/w per batch as a functional reagent, depending on target herbicide molecule and required throughput scaling. Dosage adjusted based on side-chain incorporation yield and process efficiency studies.

    Downstream process integration

    • Phase-specific alkylthiolation step during synthesis of sulfide-protected agrochemical building blocks, typically under controlled temperature and pressure with in-process GC-MS monitoring for byproduct management.

    Final product types

    • Sulfur-containing herbicide actives (e.g., thiocarbamates, thioethers)
    • Pre-formulated post-emergent weed control solutions
    • Granular or emulsifiable concentrate herbicide preparations

    2. Pharmaceutical Intermediate Production: Active Ingredient Precursor

    Cyclopentanethiol supports pharmaceutical manufacturing as a specialty synthetic intermediate for thio-functionalized building blocks in the development of investigational new drugs and generic APIs. It is primarily engaged during multi-step batch synthesis under GMP environments, where sulfur introduction into the target molecular scaffold must meet exacting purity and traceability standards applicable for regulated drug substance preparation and regulatory approval submissions.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 211 cGMP for Finished Pharmaceuticals
    • European Pharmacopoeia (Ph. Eur.) monograph references for relevant APIs
    • US Pharmacopeia (USP) for intermediate traceability and impurity controls

    Typical usage ratio

    • 1.5–4% molar equivalents relative to limiting reactant, tailored per synthetic design and impurity profile requirements validated in development batches.

    Downstream process integration

    • Selective thiolation step in small-molecule active ingredient synthesis, executed in closed-vessel reactors with full in-process quality controls and documentation for cGMP batch records.

    Final product types

    • Sulfur-containing pharmaceutical intermediates
    • Enantiomerically pure active pharmaceutical ingredients (APIs)
    • Regulatory documentation packages supporting investigational and commercial manufacturing

    3. Flavors & Fragrances: Sulfur Note Compound Synthesis

    The specialty flavors and fragrance industry employs cyclopentanethiol as a crucial sulfur-donor for synthesizing unique sulfur-based aroma chemicals. Used in the targeted production of powerful impact compounds responsible for roasted, meaty, or savory notes in high-value flavor bases, it enters highly controlled closed systems governed by international food contact safety regulations and subject to comprehensive sensory and analytical controls.

    Industry compliance standards

    • IFRA Code of Practice (International Fragrance Association)
    • FEMA GRAS (Flavor and Extract Manufacturers Association)
    • EU Regulation (EC) No 1334/2008 on flavoring substances and food ingredients
    • 21 CFR 172 Subpart F (Flavoring Agents and Related Substances, US FDA)

    Typical usage ratio

    • 0.08–0.5% w/w during aroma synthesis, depending on targeted sulfur-note impact strength in finished concentrates; usage titrated by high-dilution GC-olfactometry panel testing and application type.

    Downstream process integration

    • Manual or automated addition at the precursor synthesis stage to introduce cyclopentyl-sulfur motifs in aroma complex reactions, followed by fractionation and trace-level blending for finished fragrance and flavor blends.

    Final product types

    • Sulfur-rich aroma compounds (e.g., cyclopentylthioesters)
    • Compound flavor concentrates for snacks, sauces, and savory goods
    • Fragrance accords for perfumery requiring roasted/meaty base notes

    4. Rubber Vulcanization Additive Synthesis

    Cyclopentanethiol is utilized in the manufacture of sulfur-containing accelerators and functionalized additives for the rubber industry. Specialty downstream processors introduce this raw material during the custom synthesis of pre-vulcanization agents which improve crosslinking efficiency and mechanical resilience in technical rubber goods. Integration is precisely timed within the production of specialty additives to ensure compatibility with defined rubber compounding and vulcanization profiles.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems (Rubber Compounding)
    • ASTM D3182 (Rubber Mixing Procedures)
    • REACH Annex XVII restrictions for rubber chemicals
    • Chinese GB/T 19250 standards for synthetic rubber compounds

    Typical usage ratio

    • 0.5–3% by additive mass, depending on target rubber formulation and degree of accelerator sulfur content; formulation optimized through process validation in industrial-scale compounding lines.

    Downstream process integration

    • Direct incorporation during the synthesis of vulcanization accelerators, with subsequent integration into masterbatch mixes prior to extrusion, molding, or calendaring steps in rubber goods manufacturing.

    Final product types

    • Technical rubber additives (thio-functional accelerators)
    • Automotive and industrial rubber components
    • Chemically crosslinked elastomeric seals and gaskets

    5. Specialty Solvent Intermediate for Electronics Processing

    In high-purity electronics manufacturing, cyclopentanethiol is converted into niche thiol-based solvents and etching intermediates for the cleaning, patterning, or surface modification of semiconductors and precious metal films. Its low volatility and sulfur functionality enable controlled chemical reactivity, supporting strict purity and residue requirements essential in advanced substrate fabrication lines and microelectronics assembly plants.

    Industry compliance standards

    • SEMI C3 Chemical Specifications for Electronics
    • JEDEC JESD46 for Material Contamination Requirements
    • ISO 14644-1 (Cleanroom Environmental Standards)
    • RoHS Directive (2011/65/EU) for lead and contaminant controls

    Typical usage ratio

    • 0.02–0.2% by process bath composition; concentration optimized based on specific substrate cleaning routines, etching depth, or surface chemistry modifications calibrated with inline metrology tools.

    Downstream process integration

    • Reactive intermediate synthesis and dilution prior to batch introduction in photoresist stripping, precision cleaning, or metal etch baths within semiconductor fabrication modules.

    Final product types

    • High-purity surface modifier agents
    • Custom-formulated etching fluids for microelectronic wafers
    • Residue-free cleaning solutions for electronics substrates
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    Certification & Compliance
    More Introduction

    Cyclopentanethiol: Reliable Performance Rooted in Precision Manufacturing

    Crafting Cyclopentanethiol at Scale

    Cyclopentanethiol production reflects a balance of science and hands-on knowhow. Our facility specializes in organic sulfur compounds, and cyclopentanethiol stands as one of our cornerstone products. We approach each batch with strict attention to process controls, taking responsibility for the molecular consistency customers depend on. That comes from years spent optimizing reaction pathways, controlling temperature and moisture, and analyzing each fraction to eliminate unwanted byproducts. We do not chase shortcuts. Instead, our chemists monitor each step, whether it’s the handling of cyclopentene feedstock, the hydrogen sulfide addition, or the subsequent rectification to achieve high purity.

    Unlike traders or distributors, our experience begins at the reactor and ends at the final packing drum. The distinctive odor and reactivity of cyclopentanethiol set it apart from more common thiols, both in handling requirements and in applications. In the lab, our material consistently hits the narrow boiling range the industry calls for, keeping impurities far below the limits for organosulfur reagents.

    Understanding Cyclopentanethiol: Model, Purity, and Performance

    Our standard grade of cyclopentanethiol delivers a purity that meets or exceeds 98 percent by GC assay. The physical properties, such as boiling point near 120°C and refractive index close to 1.509 at 20°C, match published reference data, supporting both laboratory research users and larger-scale process integrators.

    Odor and volatility pose daily challenges for even the most experienced teams, yet careful engineering and exhaust management in our plant yield consistently stable results. Storage tanks, transfer lines, and filling heads all use corrosion-resistant materials for safe, controlled handling. Glass and PTFE linings, along with active odor containment, protect both operators and product integrity.

    Model consistency is not just a marketing term to us. Year after year, our chromatograms demonstrate low variance. Specifications start with purity and residual moisture, and we accept nothing less from our quality labs than rigorous testing down to the ppm level. Constant training, investment in modern GC-FID instrumentation, and a culture of accountability keep us focused on quality at every stage.

    Applications: What Sets Cyclopentanethiol Apart from Other Thiols

    Cyclopentanethiol serves as a useful building block for chemists who require selectivity in reactivity. Its five-membered ring imparts unique physical and chemical properties. Unlike open-chain thiols such as 1-pentanethiol or 2-methylpropanethiol, cyclopentanethiol provides steric and electronic effects that guide reaction outcomes in different ways.

    Our customers in the flavors and fragrance industry appreciate cyclopentanethiol for its recognizable sulfur profile, but they demand a product where off-notes and trace impurities remain low enough not to influence complex aroma formulations. In pharmaceutical synthesis, the cyclic nature of this thiol brings reaction possibilities not readily accessible with linear analogs. Medicinal chemists sometimes leverage cyclopentanethiol for the introduction of unique sulfur functionalities or for ring-opening transformations.

    Chemical manufacturers like ourselves see cyclopentanethiol step into process chemistry as a controlled sulfur source. Its moderate volatility simplifies dosing in batch reactors and feeds into flow chemistry applications with precise metering. Where other sulfur donors might contribute excess reactivity or unwanted side reactions, cyclopentanethiol gives a measured response in nucleophilic substitution, addition to activated olefins, or the preparation of intermediates for agrochemical actives.

    Real-World Insights: Feedback from Downstream Users

    We maintain close relationships with formulators, R&D chemists, and industrial engineers. Over years of feedback collection, some recurring themes keep surfacing. Small-scale users value our light and moisture-protected packaging, which preserves sample quality from the moment it leaves the drum to the final use. Larger buyers highlight the value in working with a team that knows the intricacies of the supply chain, from vessel selection to customs documentation for high-risk sulfur products.

    Several clients have told us pricing stability matters as much as purity. That’s not because they disregard quality, but because interruptions in their own supply chain cause more harm than marginal purity drops ever could. Our internal logistics staff tracks regulatory changes affecting dangerous goods, and we stay ahead of shifts in transportation laws to keep shipments punctual and compliant.

    Some users in the R&D space prefer our glass ampoule packaging for research volumes, citing lower risk of contamination. Others in continuous process environments go for our stainless-steel drums and custom containers, knowing we provide real data on cleanout protocols and drum life expectancy. For sensitive applications, they often request batch certificates, origin declarations, and impurity profiles, all of which come straight from our own analytical documentation, not generic templates.

    The Challenge of Odor and Safety: No Substitute for Experience

    Cyclopentanethiol’s strong odor cannot be ignored or covered up with technical jargon. We deal with it directly in plant operations and outbound shipments. Every new operator learns about safe handling through real examples, such as managing vapor losses during transfers or responding to minor leaks. That knowledge does not appear on any digital data sheet or brochure.

    The pungency of cyclopentanethiol sometimes limits its adoption outside professional labs. Yet, for many formulations, nothing else delivers the same chemical character. Strict attention to transfer protocols, ventilation rates, and personal protective equipment keeps our incident rate low. We document spills, investigate root causes, and refine standard operating procedures to limit community impact and maintain our environmental track record.

    We also participate in regional emergency response training and share data with local authorities. It is not just about compliance; as the producer, the burden rests on us to keep our staff, neighbors, and clients safe from both acute exposure and chronic risks. Experience in this area helps us work with customers to develop safe operational guidelines tailored to their scale and context.

    Choosing Between Cyclopentanethiol and Other Sulfur Compounds

    Industrial chemists face a landscape full of competing sulfur reagents. Cyclohexanethiol, 1-butanethiol, isopropanethiol—each brings different boiling points, reactivity, and handling nuances. Cyclopentanethiol strikes a middle ground in terms of volatility and ease of separation. Some applications require the bulkier structure of cyclohexanethiol, or the higher volatility of butanethiol when rapid evaporation is needed. Cyclopentanethiol, with its cyclic backbone, often gets picked for reactions needing stable, ring-based nucleophiles and for processes favoring compounds less prone to decomposition.

    Customers sometimes ask why they cannot simply substitute a structurally similar thiol. Our answer always comes from direct trial data and years of bench-scale testing. Prototyping a new agrochemical or designing a fragrance often produces markedly different outcomes depending on the sulfur donor used. For some derivatives, cyclopentanethiol gives higher yields or lower byproduct formation, especially in processes relying on subtle electronic effects of the ring. That difference means fewer downstream purification steps, shorter campaign times, and ultimately lower cost at scale.

    From Sourcing to Delivery: The Reality of Global Cyclopentanethiol Supply

    We have watched global trade constraints shift over the last decade, influencing both the supply of precursors and the regulatory burden on hazardous shipments. Cyclopentanethiol sits at a crossroads: its synthesis uses cyclopentene and hydrogen sulfide, both highly regulated, both in demand for other chemical processes. We devote resources to strengthening supplier relationships for raw materials and qualifying backup vendors in stable regions, so disruptions do not cascade downstream.

    Transporting finished cyclopentanethiol worldwide challenges even experienced teams. Some ports increase restrictions or add inspection steps without warning. Documentation for sulfur compounds grows more complex each year, with environmental requirements, classification changes, and new product stewardship codes added regularly. Because we operate our own supply chain, we adapt quickly to these changes, whether by changing drum types, adding new liner materials, or reworking our customs filings.

    Some customers have switched to us from dealers when they grew weary of variable quality or unreliable import schedules. Direct purchase from the manufacturer does not simply mean a better price; it gives transparency on batch history, full documentation, and real accountability in the event of an issue. Strong supply chain partnerships have helped us keep quality high and delays low, even as regional disruptions have become more common.

    Quality And Environmental Responsibility: Keeping Standards High

    We hold our cyclopentanethiol to international benchmarks, using constant internal and third-party audits to track quality and compliance. Internal training covers not only product specs but also safety culture and environmental stewardship. Hazardous waste handling tied to sulfur chemistry draws special scrutiny. Regulatory bodies audit processes regularly, and we keep detailed documentation to track the fate of each shipment and batch by batch.

    Our location near major industrial corridors helps us minimize overall transport distance, reducing risk and environmental load compared to long-haul routes through multiple logistics providers. We also engineer in facility upgrades to lower overall emissions—installing advanced scrubbers, refining tank farm layouts, and switching to closed-loop vapor recovery. The ongoing investment in these areas demonstrates real-world commitment, not simply aspirational greenwashing.

    Some of our customers require detailed lifecycle analyses or sustainability disclosures for procurement. We support these requests, delivering specific data: raw material origin, energy consumption for each process step, and carbon emissions tracking. Meeting and exceeding regulatory standards protects our license to operate and allows downstream users to meet their own compliance targets, providing mutual benefit rather than shifting the burden down the chain.

    Research and Product Development: Supporting Innovation in Sulfur Chemistry

    Each year brings new requests from R&D centers asking about custom batches or novel derivatives. Some want enrichment with isotopically labeled sulfur, others request ultralow impurity variants, and a few ask for stabilized blends for specialty synthesis. Success here comes from real collaboration—not just opening a catalogue, but working through experimental failures, unexpected equipment fouling, or new clean-in-place routines for reactor prep.

    Development work never offers quick wins. Experience with cyclopentanethiol tells us what filtering aids to use, how to handle high-purity distillation under inert atmospheres, and when to switch from batch to continuous operation for better control. We lend this experience to research teams taking on new processes, helping them troubleshoot and plan pilot-scale campaigns with confidence.

    Some innovations have arisen directly from customer collaboration. We’ve been asked to supply custom blends, coordinate test shipments under expedited regulatory review, or provide technical data on long-term stability that only a hands-on manufacturer can generate. These projects build trust and allow both sides to push into new product spaces, without sacrificing reliability or regulatory compliance.

    Future Directions and Industry Challenges

    Looking forward, the demands on cyclopentanethiol and related products will not let up. Environmental policies, raw material availability, and new applications in pharma, crop science, or electronics shape our investment in plant upgrades and process innovation. Customers increasingly request supply chain transparency, greener production methods, and detailed safety data. Meeting these expectations means ongoing investment in both people and technology: energy-efficient reactors, digital batch tracking, and expanded process simulation.

    We live in a world more aware of chemical impacts and regulatory scrutiny. That doesn’t discourage us; it motivates measured innovation and solid planning at every level. By delivering a consistent supply of high-quality cyclopentanethiol, we support customers who depend on stable reagents for their own breakthroughs. This ongoing partnership with end users, rooted in expertise rather than marketing spin, keeps us improving batch after batch.

    Working with the Manufacturer: Direct, Transparent Support

    Choosing a direct source for cyclopentanethiol simplifies many challenges. Customers gain a reliable partner for complex technical issues rather than a faceless supplier. We take calls about drum compatibility, disposal practices, emergency offloads, or about scaling a small-sample result to production drums. It comes with a commitment—a willingness to help troubleshoot and a readiness to own both mistakes and successes.

    Direct links between us as the manufacturer and customers in the field foster trust, shared knowledge, and mutual improvement. Clear communication—about changes in spec, shifts in feedstock purity, or potential delays—prevents surprises and builds long-term relationships. This transparency draws repeat business from those who value the peace of mind only firsthand experience provides.

    Final Thoughts: Why Our Cyclopentanethiol Earns Trust

    Our foundation has always rested on technical expertise and practical reliability. Every drum or ampoule carries the weight of our commitment to doing things properly—from raw material selection to waste treatment, from odorous offgassing to end-use application support. We do not weave generic claims about versatility or efficiency; the feedback and loyalty from customers demonstrate our value.

    Cyclopentanethiol, with its specific chemical profile and real handling demands, deserves respect in both how it’s made and how it is put to use. Drawing from decades of manufacturing experience, continual investment in process improvements, and a culture rooted in real-world accountability, our approach focuses on facts, measured innovation, and enduring service to the chemical community.