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Cyclohexanecarboxylic Acid Ethyl Ester

    • Product Name Cyclohexanecarboxylic Acid Ethyl Ester
    • Alias Ethyl cyclohexanecarboxylate
    • Einecs 202-251-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    479952

    Cas Number 831-13-6
    Molecular Formula C9H16O2
    Molecular Weight 156.22 g/mol
    Appearance Colorless liquid
    Boiling Point 210-212°C
    Melting Point -24°C
    Density 0.957 g/mL at 25°C
    Refractive Index 1.444-1.447
    Flash Point 91°C
    Solubility In Water Insoluble
    Odor Characteristic ester odor
    Purity Typically ≥98%
    Synonyms Ethyl cyclohexanecarboxylate
    Storage Temperature Store at room temperature
    Applications Used in flavors, fragrances, and as an intermediate in organic synthesis

    As an accredited Cyclohexanecarboxylic Acid Ethyl Ester factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 mL amber glass bottle with airtight cap, labeled "Cyclohexanecarboxylic Acid Ethyl Ester," includes hazard symbols and safety instructions.
    Shipping Cyclohexanecarboxylic Acid Ethyl Ester should be shipped in tightly sealed containers to prevent leakage and evaporation. Store and transport it in a cool, dry, and well-ventilated area, away from heat or open flames. Follow all relevant regulations for flammable liquids, and include appropriate hazard and identification labels on packaging.
    Storage Cyclohexanecarboxylic Acid Ethyl Ester should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep away from incompatible substances such as strong oxidizing agents and acids. Store at room temperature and ensure proper labeling. Avoid prolonged exposure to air and moisture to maintain chemical stability.
    Application of Cyclohexanecarboxylic Acid Ethyl Ester

    Applications of Cyclohexanecarboxylic Acid Ethyl Ester in Industrial Manufacturing

    Cyclohexanecarboxylic Acid Ethyl Ester serves as a specialized intermediate in multiple industrial sectors. Our proprietary production methods enable stable supply with consistent purity, supporting advanced manufacturing requirements. Detailed below are the main downstream sectors and precise application specifics for each scenario.

    1. Fragrance Ingredient Synthesis in Fine Chemical Manufacturing

    The ester’s stable structure and low volatility make it a reliable intermediate for the synthesis of complex aroma chemicals. Manufacturers utilize it for building high-value fragrance molecules, especially those requiring cycloaliphatic features, due to its compatibility with multi-step reactions and tolerance under common Grignard and Friedel–Crafts conditions. Typical processes incorporate it into reaction chains post-nitration or hydrogenation to preserve olfactory qualities and batch consistency throughout scale-up.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association)
    • OECD SIDS for fragrance material safety
    • REACH Annex XVII for restricted substances
    • SCCS Notes of Guidance (for cosmetic fragrance applications)

    Typical usage ratio

    • As an intermediate: 2–8% molar equivalent in synthesis batches
    • Adjusted based on target functionalization and yield optimization

    Downstream process integration

    • Employed after primary cyclization or hydrogenation steps
    • Reacted with alcohols or phenols to create esterified fragrance cores

    Final product types

    • Key notes for fine perfumes
    • Functional fragrances for detergent or home care products
    • Non-toxic fragrance additives for personal care

    2. Pharmaceutical Intermediate for API Synthesis

    Pharmaceutical manufacturers select this ester for constructing cycloaliphatic moieties in specialty APIs. Its use enables controlled introduction of ester groups, key for prodrug strategies and modification of pharmacokinetic profiles. Production facilities directly integrate this compound during esterification stages when synthesizing non-aromatic backbone drugs, maintaining GMP control and traceability over each critical step.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP) as per ICH Q7
    • EU Directive 2011/62/EU (Falsified Medicines Directive)
    • USP–NF requirements for intermediates
    • Controlled substance precursor monitoring where regionally required

    Typical usage ratio

    • Intermediate input: 5–20% stoichiometric ratio per reaction protocol
    • Ratio set according to desired final API yield and impurity profile

    Downstream process integration

    • Esterification step prior to hydrolysis or amidation in API synthesis
    • Integrated into continuous flow or batch reactor setups

    Final product types

    • Cycloaliphatic active pharmaceutical ingredients
    • Prodrug precursors for improved solubility and bioavailability
    • Intermediate building blocks for custom fine chemicals

    3. Resin Monomer Precursor in Polymer Manufacturing

    Cyclohexanecarboxylic Acid Ethyl Ester is widely used as a chain-modifying precursor for specialty polyesters and alkyd resins. Polymeric applications value its ability to introduce controlled cycloaliphatic rigidity, increasing the resulting resin’s gloss, weathering resistance, and compatibility with flexible coatings. Integration occurs in prepolymer stages where controlling the acid to ester ratio is critical for polymer molecular weight and final film properties.

    Industry compliance standards

    • ISO 9001 for quality management
    • ASTM D3029/D704 for polyester and alkyd resin specifications
    • EHEDG Guidelines (for food-contact resins, if applicable)

    Typical usage ratio

    • Monomer charge: 3–15% by weight of total acid/ester content
    • Ratio selected based on polymer type (thermoset vs. thermoplastic)

    Downstream process integration

    • Co-charged with diols and polyacids in transesterification reactors
    • Used in melt polymerization before final chain extension

    Final product types

    • Architectural and industrial coatings
    • Flexible packaging films
    • Adhesive binders requiring enhanced aging stability

    4. Agrochemical Building Block for Ester-Linked Herbicides

    In agrochemicals, the ester’s cycloaliphatic core enables synthesis of high-stability compounds used in modern herbicide formulations. The structure resists environmental degradation, providing longer residual activity on crops. Production facilities utilize it during final coupling reactions, attaching functionalized side chains under strict batch controls, meeting regulatory maximum residue limits for finished products.

    Industry compliance standards

    • FAO/WHO JMPR pesticide specifications
    • OECD Guidelines for Testing of Chemicals
    • ISO 17025 laboratory accreditation for process QC
    • EU Regulation (EC) No 1107/2009 on plant protection products

    Typical usage ratio

    • Active intermediate loading: 7–15% on total active content basis
    • Adjusted based on target molecule and application spectrum

    Downstream process integration

    • Condensation reaction with heterocyclic or aromatic amines
    • Post-synthesis purification and granulation for formulated products

    Final product types

    • Ester-based pre-emergent and post-emergent herbicides
    • Controlled-release agrochemical granules
    • Non-volatile selective weed control agents
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    Certification & Compliance
    More Introduction

    Cyclohexanecarboxylic Acid Ethyl Ester: Practical Insights from the Manufacturer’s Bench

    Getting to Know Cyclohexanecarboxylic Acid Ethyl Ester in Daily Manufacturing Practice

    Plenty of chemicals pass through our tanks and reactors, but Cyclohexanecarboxylic Acid Ethyl Ester stands out in its role across industries as a versatile intermediate. We’ve walked thousands of liters through distillation columns, tested fractions coming through the glass reactor, and watched as organic synthesis demands pushed product expectations higher every year. This compound shows up in flavor creation, specialty chemical formulation, and even among active pharmaceutical ingredients. Its CAS number—though recorded for identification—matters less to the lot operator than purity, reliable supply, and application know-how.

    Understanding Specifications—By the Numbers, but Not by Numbers Alone

    Let’s be real about specs. Cyclohexanecarboxylic Acid Ethyl Ester usually appears as a clear, colorless liquid when produced under good conditions. Odor comes mildly fruity—sometimes reminiscent of pear, a hint that gets noticed during quality control checks more than most people think. We control purity with GC, regularly above 99 percent for specialty orders. Impurities usually land below 0.5 percent, a figure based on tight, consistent column operation rather than pure chance or theoretical batch claims.

    Water content can cause headaches down the line, so we work with less than 0.2 percent moisture, measured by Karl Fischer titration. Maintaining this low moisture lets customers avoid surprises during downstream applications, like side reactions or slowed kinetics. Boiling point sits close to 227°C under normal conditions, and this number is not trivial. Accurate distillation gives better product, cleaner downstream synthesis, and fewer customer complaints.

    Density and refractive index might seem like dry numbers, but in real daily checks, watching for outliers saves time before batches hit the filling line. Our results typically run at a density around 0.98 g/cm3 at 20°C, and a refractive index of roughly 1.4490. Though some overseas suppliers claim wild ranges, hard in-process readings nail down an honest shipment, not just paperwork compliance.

    Usage: On the Ground, On the Line, On the Lab Bench

    Cyclohexanecarboxylic Acid Ethyl Ester finds regular usage in flavors and fragrances. Small-scale artisan operations want consistent notes for fruit flavors, whereas big fragrance producers need predictable properties in every drum. Every batch we move down the line faces both sensory and analytical checks, since aroma compounds require both subtlety and chemical reproducibility. We’ve seen how even trace residual solvents or process impurities can skew a finished formulation—customers notice, and so do their clients.

    Pharmaceutical manufacturers sometimes value this ester as a precursor or building block. We’ve handled requests for GMP-level production and know the importance of batch documentation and traceability back to a single reactor run. The pharma world tolerates no ambiguity, so meeting their needs pushes us to higher verification standards, not just “typical” commercial purity.

    In fine chemicals and research, the ester’s role varies based on target molecules, but we often hear from R&D labs pushing boundaries. Flexibility and openness about process data allow us to serve researchers looking to modify routes or shift yield curves. We work closely, offering real production insights on handling, storage, and reaction compatibility—since everyone in the lab wants to know if this ester throws off by-product traps or complicates downstream purification.

    Major Differences from Other Esters—Beyond the Similar-Sounding Names

    Several customers still confuse Cyclohexanecarboxylic Acid Ethyl Ester with linear chain esters, such as Ethyl Hexanoate or Ethyl Caproate, simply because the names sound similar and both relate loosely to “fruity” odors. In the reactor, though, the story couldn’t be more different. Ring structure in the cyclohexane core steers reactivity in a different direction: stability in harsh process conditions, steric effects in synthesis, and a unique volatility profile that fits certain applications and not others.

    Linear esters might give lighter, more straightforward notes in flavoring and evaporate more readily, but they can’t withstand higher temperatures without noticeable breakdown. Cyclohexanecarboxylic Acid Ethyl Ester holds up under extended heating—critical for some fragrance and specialty chemical syntheses where flash-off or degradation becomes a risk. This resilience also means longer shelf life in real-world warehouse conditions, especially in less-than-perfect climate control.

    Solubility patterns differ. While both linear and cyclic esters dissolve in alcohols and non-polar solvents, cyclohexane-based esters avoid instability in water-rich systems better than some of their counterparts. That matters to product formulators aiming for emulsion stability or layering several performance additives in a single bottle.

    From our own production troubleshooting, we see Cyclohexanecarboxylic Acid Ethyl Ester remains friendlier in storage than many straight-chain esters. It resists hydrolysis longer, especially in regions with hot, humid summer months. Shipments headed for tropical climates often receive extra attention—liners, drums, and labeling to prevent accidental contamination.

    Product Handling: What Manufacturing Really Teaches You

    Anyone can recite MSDS guidelines, but until you’ve stood next to a 3,000-liter batch after a night shift, you don’t truly understand the importance of careful product transfer and documentation. Cyclohexanecarboxylic Acid Ethyl Ester must stay dry from synthesis through to customer intake. Well-trained operators check line purges before bulk transfer. We tag every valve and make double certain inert gas blanketing remains active during storage. Oxygen exposure means slow degradation, off notes in fragrance work, and, in pharmaceutical contexts, batch rejection. These details might not show up in all marketing brochures but matter every day on the shop floor.

    Packaging typically goes into HDPE drums or IBCs, rigorously cleaned and checked for any points of weakness or residual contaminants. Our warehouse staff tracks shipment temperature and humidity because out-of-spec storage can affect not just current but future orders, as shelf stability affects long-term business reputation more than the marketing buzzword “quality” ever could.

    Our loading operators and drivers have all been through on-the-ground safety drills, with regular live training sessions. Incidents on the road or at a customer site affect everyone, from the most senior plant engineer to the newest packer—eventually, word gets around if loads are not prepared with care.

    Why Consistent Quality Demands Attention and Investment

    We’ve worked hard to bring analytical equipment onsite, so every batch gets its full round of GC and IR checks instead of being farmed out to a third-party tester. Speed, accuracy, and transparency keep us close to real-world problems. Copy-pasting a certificate of analysis or turning a blind eye when a result skates just inside spec is not our style.

    With Cyclohexanecarboxylic Acid Ethyl Ester, color and clarity often flag up upstream process problems well before a major failure hits yield or performance. A slight yellowing in a batch told us once that a heat exchanger had fouled up—the fix not only kept the customer order on track but prevented scrapped inventory from spiraling into a bigger loss.

    Sourcing raw materials to match our production quality makes or breaks many campaigns. Synthetic cyclohexanecarboxylic acid from reputable plants cuts down on unexpected impurities and reduces batch reworks. Batch failures become rare events, not routine. In nearly two decades of experience, we’ve noticed markets are less forgiving than they used to be—every off-batch carries a real cost.

    Traceability increasingly matters as more customers seek assurance about every step in the chain. Gone are the days when “country of origin” ticked enough boxes. Now, accurate, stepwise records track each raw material drum through synthesis, purification, packaging, and distribution.

    Challenges in the Current Global Environment

    Over the last few years, global trade upheavals and tighter regulatory standards have shifted the way people think about chemical sourcing. Cyclohexanecarboxylic Acid Ethyl Ester hasn’t been immune to shipping delays, packaging shortages, or new environmental rules. Our production crew responded by modifying schedules to prioritize essential compounds and by qualifying alternative suppliers for raw materials, all with frequent, direct communication with customers about progress and changes.

    Increased environmental consciousness has also forced us to review waste streams, solvent choices, and energy usage during ester synthesis. We invested in energy recovery from distillation, reducing steam loads and cooling water use. These smaller steps matter deeply—not only for compliance but for lasting relationships with both global customers and local neighbors. Our plant’s emissions dropped substantially, and while cyclohexane-based esters are not among the most notorious for environmental risk, no one here takes their handling lightly.

    Supply chain auditors walk the production floor with a different set of questions than before. Robust batch tracking, complaint resolution logs, and operational transparency have never seemed more relevant. Our insistence on above-board reporting often means handling more paperwork and increased scrutiny—still, nobody in the control room wants to be on the receiving end of a recall, especially if it could be traced to a controllable process step.

    Customer Experience: Working Together Toward Better End Products

    Over years, customer requirements shaped our production rhythm for Cyclohexanecarboxylic Acid Ethyl Ester. Big batch runs for established brands, small lots for development labs, rush orders for an unplanned campaign—we’ve done all of these. What stands out is how success follows conversations, not just specifications. Customers report reduced need for in-house purification when sourcing from us, a point we track closely in returned data and feedback. That means fewer headaches for production chemists and fewer hours wasted on repeat chromatography, distillation, or filtration steps.

    Many new inquiries arrive from start-ups just getting off the ground, sometimes through word-of-mouth, sometimes from public presentations at trade events. They want as much candid input as possible. Our sales staff, all with plant floor experience, take pride in discussing pitfalls as openly as possibilities—real data, practical workarounds, and creative formulations. No one wants to sell a batch if it means trouble downstream; we prosper only when customers do.

    Comparison: Experience with Similar Specialty Esters

    Experience draws sharp lines between Cyclohexanecarboxylic Acid Ethyl Ester and similar-sounding products. For example, Ethyl Benzoate, a popular aromatic ester, brings a strong, distinctly floral scent but lacks the hydrolytic stability of our cyclohexane derivative. Several research clients learned this after wrestling with unwanted transesterification during scale-up. In our lab, such differences come to light quickly—one remains stable toward alkaline hydrolysis; the other does not.

    Ethyl Cyclohexanecarboxylate also holds a place in polymer chemistry as a monomer or plasticizer, but Cyclohexanecarboxylic Acid Ethyl Ester rarely substitutes directly without adaptation. Each molecule, though similar at a glance, answers differently to polymerization conditions and thermal stress. The lesson is clear after decades in production; one must think beyond name or CAS to real-world function.

    We also field requests comparing our product with methyl esters. Ethyl esters, including Cyclohexanecarboxylic Acid Ethyl Ester, offer a friendlier scent profile for most aromatics and show better volatility curves in controlled-release formulations. The methyl analogues, on the other hand, often come with sharper, more volatile characteristics, which might interfere with the intended effect in fragrance or slow-release drug products.

    Our team encourages on-site testing whenever possible—we routinely send kilogram samples rather than just paperwork, because customer lab validation often catches subtleties not seen by numbers alone. Color hold, evaporation rate during processing, and sensory impressions measure up differently on different production lines or in distinct environments. We get these reports returned directly to the process crew, who often suggest tweaks for future batches. This feedback loop shortens lead times on new application trials and keeps everyone moving together.

    Future Directions and Solutions for Ongoing Challenges

    Our plant isn’t standing still. Digital process monitoring steps in where handwritten logs used to dominate. Realtime data on pressure, temperature, and flow allows for early adjustments—a bleed valve stuck open no longer ruins a full batch before someone notices. Investment in online GC gives us the confidence to guarantee tighter spec variation and alert customers far sooner about potential hiccups.

    As regulations tighten and buyers grow more discerning, we’re doubling efforts to anticipate trace impurity requirements—for both flavor/fragrance and pharma grades. Filtering, polishing, and even new column resins all feature in the research budget for the year ahead. Regular supplier audits and secondary sourcing agreements strengthen our grip on upstream quality, particularly during times of shipping bottlenecks or raw input volatility.

    We’re also exploring packaging changes. Customers in hot climates saw unexpected minor hydrolysis when using recycled plastic drums lacking robust liners. We responded with targeted upgrades, switching to multilayered, virgin-HDPE drums, and improving venting protocols to control internal humidity and pressure swings. These incremental improvements build resilience, not just for us, but for everyone downstream. It’s these kinds of plant-floor learnings, often born of troubleshooting a real complaint, that make all the difference—long after spec sheets are filed away.

    Working With Us: Partnership Beyond Solo Transactions

    Making Cyclohexanecarboxylic Acid Ethyl Ester is more than reaching a listed specification—it’s a conversation every day between chemical realities, customer ambitions, and changing global markets. We invest in our people, process controls, and supply network not just to meet orders but to keep adapting. As we see new uses and stricter norms emerging, our job means offering honest, practical guidance and standing with you if troubleshooting is needed. One learns over time in this business that success is earned batch by batch, run by run, through both the routine and the unexpected.

    Anyone ready to discuss next steps will find us straightforward, attentive, and deeply interested in long-term solutions. From pilot drums to major contract manufacturing, we know from experience that clear advice and diligent process attention shape better results—for both sides of the deal.