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Coniferyl Alcohol

    • Product Name Coniferyl Alcohol
    • Alias 3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-ol
    • Einecs 208-038-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    867703

    Cas Number 458-35-5
    Molecular Formula C10H12O3
    Molecular Weight 180.2 g/mol
    Iupac Name 4-hydroxy-3-methoxycinnamyl alcohol
    Appearance White to off-white crystalline solid
    Melting Point 90-95 °C
    Boiling Point 345 °C
    Solubility In Water Slightly soluble
    Density 1.18 g/cm³
    Pubchem Cid 8587
    Smiles COC1=CC=C(C=C1O)C=CCO
    Flash Point 184 °C
    Refractive Index 1.585

    As an accredited Coniferyl Alcohol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Coniferyl Alcohol is typically supplied in a 25g amber glass bottle, labeled with product details, hazard warnings, and manufacturer information.
    Shipping Coniferyl Alcohol is shipped in tightly sealed containers made of glass or compatible plastic to prevent contamination and evaporation. It should be stored and transported in a cool, dry, well-ventilated area, away from heat, moisture, and direct sunlight. Proper labeling and adherence to relevant chemical transport regulations are required.
    Storage Coniferyl alcohol should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and direct sunlight. Keep the container tightly closed and protected from moisture. Store separately from oxidizing agents and strong acids. Proper labeling and secure storage are essential to prevent accidental exposure or contamination. Follow all relevant safety guidelines and regulations for chemical storage.
    Application of Coniferyl Alcohol

    Applications of Coniferyl Alcohol in Industrial Manufacturing

    Coniferyl alcohol is a key biochemical building block used in specialized sectors of industrial manufacturing, especially for advanced organic synthesis, fine chemicals, and high-value biochemical intermediates. Below are the major downstream applications where coniferyl alcohol is used as a functional ingredient or intermediate, supplied directly to industry under stringent manufacturing protocols.

    1. Lignin-Based Resin Production

    Industrial manufacturers use coniferyl alcohol as a primary precursor in the synthesis of lignin-based phenolic resins. These resins provide enhanced mechanical properties and eco-friendly composition for plywood, laminates, and moulded components. Resin plants incorporate coniferyl derivatives during initial polymerization with formaldehyde under alkaline conditions. Careful control over the phenol-to-aldehyde-to-coniferyl alcohol ratio enables tuning of curing speed and final rigidity, meeting strict physical property requirements for construction and engineered wood products.

    Industry compliance standards

    • EN 13986:2004+A1:2015 (Wood-based panels for construction)
    • ASTM D5055 (Laminated veneer lumber)
    • ISO 9001:2015 (Quality management in chemical processing)
    • OSHA 1910.1200 (Hazard communication for raw chemical handling)

    Typical usage ratio

    • 5–15% coniferyl alcohol in the monomer mixture, adjusted to polymer molecular weight requirements and final application mechanical standards.

    Downstream process integration

    • Operators dose coniferyl alcohol into the resin reactor during the initial condensation stage with phenol and formaldehyde.

    Final product types

    • Plywood adhesives
    • Exterior structural panels
    • Laminated wood beams
    • Moulded building blocks

    2. Synthesis of Flavonoid Compounds for Nutraceuticals

    In the nutraceutical industry, coniferyl alcohol serves as a core precursor for the synthesis of natural flavonoids through biocatalytic and chemo-enzymatic routes. Advanced manufacturers use it to produce intermediates like naringenin and catechins for functional foods and dietary supplements. The process involves oxidation and rearrangement of coniferyl alcohol under controlled pH and enzymatic conditions, with meticulous monitoring of by-product formation to ensure food-grade purity.

    Industry compliance standards

    • USP-NF (United States Pharmacopeia – Nutraceutical Ingredients)
    • 21 CFR Part 111 (cGMPs for Dietary Supplements)
    • EFSA Food Additive & Ingredient Approvals
    • ISO 22000:2018 (Food Safety Management Systems)

    Typical usage ratio

    • Starting molar ratio varies from 1:2 to 1:5 (coniferyl alcohol to enzyme/co-factor), depending on the specific flavonoid target and process kinetics.

    Downstream process integration

    • Utilized in specialized bioreactors during the initial substrate loading stage; adjusted for conversion rates above 95% for nutraceutical-grade output.

    Final product types

    • Flavonoid additives (naringenin, catechin)
    • Antioxidant tablets and capsules
    • Functional gummies and powders
    • Enriched beverages

    3. Vanillin Synthesis for Food and Fragrance Industries

    Many food and flavor manufacturers use coniferyl alcohol as an intermediate in the biotransformation route for vanillin. In controlled fermentation systems, coniferyl alcohol undergoes oxidative cleavage, yielding vanillin that meets global food additive standards. This method allows for "natural origin" labeling and traceability, especially valued in premium confectionery and beverage applications. Quality teams monitor each batch for compliance with food grade purity limits, minimizing residual precursors and by-products.

    Industry compliance standards

    • FCC (Food Chemicals Codex – Vanillin)
    • EU Regulation (EC) No 1334/2008 (Food flavorings)
    • ISO 14034 (Environmental management for biotechnological process)
    • FSSC 22000 (Food Safety System Certification)

    Typical usage ratio

    • 1:1.2 molar input (coniferyl alcohol:fermentation catalyst), with fine-tuning for fermentation yield and downstream purification requirements.

    Downstream process integration

    • Dosed into fermentation vessels as the key initial substrate, followed by aqueous work-up and aroma purification stages.

    Final product types

    • Vanillin flavoring agents
    • Bakery ingredient blends
    • Perfume bases
    • Premium ice cream inclusions

    4. Phytochemical Synthesis in Research-Grade Fine Chemicals

    Coniferyl alcohol is integral to the preparation of reference phytochemicals for pharmaceutical R&D and analytical laboratories. Researchers use it for small-scale synthesis of lignans and coumarins, running tightly controlled reactions to ensure structural integrity and reproducibility. The substance enters the synthesis at the alkene functionalization stage, demanding anhydrous, inert conditions and traceability in accordance with laboratory quality management frameworks. These high-purity derivatives support assay validation and bioactivity testing in regulated environments.

    Industry compliance standards

    • ISO/IEC 17025:2017 (Testing and calibration laboratories)
    • IUPAC Analytical Chemistry Validation Protocols
    • GLP (Good Laboratory Practice, OECD Series on Principles)
    • Ph. Eur. 10.0 (European Pharmacopoeia for analytical standards)

    Typical usage ratio

    • 10–50 mmol scale per batch, precisely calculated according to synthetic requirements for the target structure.

    Downstream process integration

    • Charged as a primary reactant in the first step of lignan or coumarin synthesis, followed by multi-step purification and structural validation.

    Final product types

    • Lignan analytical standards
    • Coumarin reference materials
    • Bioactive screening compounds
    • Method validation kits for research labs

    5. Polymer Additive Manufacturing for Coatings

    Producers of specialty coatings and biodegradable packaging integrate coniferyl alcohol-based oligomers into polymer formulations to modulate hydrophobicity and crosslink density. Factories blend this ingredient with acrylate or polyurethane precursors in melt or solution processes, directly influencing curing rate and final flexural strength. Regular QC checks verify integration at targeted polymer chain positions, adhering to industry-specific environmental and user safety standards.

    Industry compliance standards

    • REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals, EU)
    • RoHS 3 Directive 2015/863/EU (Restriction of Hazardous Substances)
    • ISO 12944 (Paints and varnishes – Corrosion protection of steel structures)
    • FDA 21 CFR 175.300 (Resinous and polymeric coatings in food contact)

    Typical usage ratio

    • 2–8% by polymer mass, determined after pilot-scale film thickness and mechanical property validation.

    Downstream process integration

    • Added post-polymerization as a modifier during the blending stage, or in situ during controlled polymer chain propagation.

    Final product types

    • Bioresin-based can coatings
    • Bio-polymer packaging films
    • Specialty surface sealants
    • Water-resistant protective layers
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    Certification & Compliance
    More Introduction

    Coniferyl Alcohol: From Lignin Science to Practical Innovation

    Understanding Coniferyl Alcohol’s Origins

    Sourcing and producing coniferyl alcohol has always meant digging deep into nature's toolkit, and understanding how plants put together their cell walls. As a chemical manufacturer, our work borrows a page from that natural process. We look at how softwood trees, especially conifers, use coniferyl alcohol as a building block in their lignin structure. Replicating this in the lab, we learn a lot about what makes this molecule special—reactivity, purity, and consistency. Experience in fermentation, separation, and laboratory synthesis shapes the product we bring out to the market. Every batch reflects precise control over temperature, pressure, and feedstock selection, which in turn influences the crystal structure and chemical behavior of the final product.

    Technical Details and Specifications

    Coniferyl alcohol, with its chemical structure rooted in the cinnamyl alcohol family, carries a hydroxyl and a methoxy group that set it apart. Our manufacturing process achieves a product purity upwards of 98%, which is the benchmark for advanced research and downstream applications. The crystalline, pale white powder is engineered for both solubility and stability. Melting point ranges consistently between 78°C and 80°C, confirming the product’s reliability during storage and subsequent processing. Water content registers below 0.5%, a crucial spec for those who depend on reaction predictability. Our labs conduct repeated HPLC and NMR analyses to ensure each lot matches these specifications, minimizing variability and satisfying strict regulations in customer protocols.

    Shaping Research and Industrial Use

    Chemists and product developers turn to coniferyl alcohol for its versatility. In biomaterials research, the compound serves as a reference standard to unravel the lignification process, supporting breakthroughs in sustainable papermaking and bio-composites. In flavors and fragrances, its subtle, plant-derived aroma underpins the creation of true-to-nature synthetics. Enzymology labs use coniferyl alcohol to screen laccases and peroxidases, building newer enzyme cocktails for eco-friendly pulp bleaching and textile processing.

    Several industrial clients ask about coniferyl alcohol for its role in constructing higher-value vanillin and other aromatic aldehydes. Our process enables scalable access to this rare phenolic, bridging the gap between milligrams for research and kilograms for pilot production. Every shipment rests on a lot-specific certificate of analysis, which tracks chemical fingerprinting from sourcing through finished goods—crucial for audit trails and troubleshooting in regulated sectors, including pharmaceuticals.

    What Makes Our Coniferyl Alcohol Different

    Years of processing and feedback from diverse industries have reshaped how we think about quality. We don’t just supply a commodity; we deliver a high-purity biochemical precisely calibrated for predictable results. Much of our clientele works in fields where one minor impurity can derail an entire batch—be it in industrial fermentation, biopolymer formation, or enzymatic assays. Our production lines integrate in-house developed purification routines. These do more than filter out foreign matter; they cut down on isomers and degradation products, ensuring that every container meets the purity and performance profile demanded by cutting-edge labs.

    Compared to standard grades often pushed through less controlled channels, our coniferyl alcohol undergoes additional layers of synthetic optimization and analytical scrutiny. We handpick batches that meet not just published specifications, but also internal markers for moisture stability, shelf-life, and photoreactivity. This speaks directly to the needs of those experimenting with stress-testing new materials, developing analytical reference standards, or searching for a robust base compound for value-added chemical synthesis.

    Real-World Feedback: Direct From Our Clients

    Over the last decade, feedback from both small research teams and larger pilot operations has shaped the molecule’s reputation. Several institutes focused on lignin valorization consistently note that our product takes less time to dissolve, with fewer problems during scale-up. Food and flavor developers emphasize the reduction in off-notes and improved aroma balance when starting with a high-purity coniferyl alcohol. Technical partners experimenting with oxidative coupling appreciate that side-product formation stays minimal, thanks to a tighter distribution of starting material.

    We’ve watched novel applications emerge, particularly in the pharmaceutical segment, where coniferyl alcohol derivatives serve as lead compounds. In polyphenol research, labs running multi-step syntheses from coniferyl alcohol often share that process losses dip when the input chemical comes precisely characterized. Not only does this trim costs—it also accelerates product launch timelines by cutting back on QC bottlenecks.

    Solving Industry Challenges With Careful Production

    Meeting industry demand challenges more than raw production capacity. Weaves of global supply chain uncertainty, shifts in environmental legislation, and rising analytical standards keep us vigilant. Unlike materials with looser documentation or origin uncertainty, our coniferyl alcohol backs every shipment with traceability, from initial plant source or synthetic pathway through purification and packaging. This full line-of-sight answers questions during regulatory checks, helping clients avoid customs or registration hurdles.

    Another challenge that returns year after year involves batch-to-batch consistency. Small impurities, or even slight shifts in physical texture, can cause issues in process development and regulatory submissions. To tackle this, in addition to NMR and GC-MS monitoring, we maintain a retained sample archive for every lot. In practice, this means that long-term projects—such as government-funded studies or clinical projects—never face setbacks due to source inconsistency. Our aim: to become an extension of the research workflow rather than just a supplier.

    Building for Environmental and Regulatory Needs

    Green chemistry pressures drive both changes in production and client expectations. Sourcing choices reflect a balance between plant-derived precursors and synthetic alternatives, with each route tuned for atom economy and waste reduction. Process solvents undergo recycling, so we keep secondary waste streams to a minimum. Where feasible, we support chain-of-custody reporting, important for eco-certifications and sustainable manufacturing claims.

    For customers facing increasingly intricate compliance regimes, product documentation becomes an asset. We respond to requests for regulatory support—not just by attaching a generic data sheet, but by producing full composition breakdowns, impurity profiles, and if needed, REACH or RoHS covering letters. This proactive support creates value downstream, since many customers later face audit requests or product stewardship reviews where details matter.

    Tuning Coniferyl Alcohol to Application Needs

    Customers working in advanced materials often ask for a tailored approach—sometimes for higher-purity, sometimes for specific particle sizes for optimized dissolution. Our development labs have responded by piloting small-batch customizations alongside the main production run. Scale-up testing, reactivities, and storage trials become part of our service, so customers get what’s required without months of hard negotiation or switching to new products.

    Research collaborations have also led us to investigate crystal structure variants and polymorphs, since these impact reactivity for certain biopolymer and fermentation projects. Providing options—such as differing hydration states or micronized forms—means researchers carry out experiments with the right starting materials, instead of reworking protocols or losing weeks of development time.

    What Sets Coniferyl Alcohol Apart From Similar Compounds

    Structurally, coniferyl alcohol is closely related to sinapyl alcohol and p-coumaryl alcohol. Many clients come to us for clarity on why one would serve better than another. In the lignin biosynthesis pathway, coniferyl alcohol forms guaiacyl units, making it the dominant monomer for softwoods. This leads to downstream differences in the polymers and degradation products obtained during chemical pulping or advanced oxidative breakdown. Choosing the right monolignol matters: you see distinct performance in enzymatic study outputs, resistance to fungal breakdown, and final polymer mechanical properties.

    From a practical perspective, coniferyl alcohol’s melting point, solubility, and oxidation profile make it more manageable on the benchtop than bulkier or less stable relatives. For oxidation reactions, it tends to form well-defined quinone methide intermediates, easing kinetic studies and facilitating targeted derivatization. This advantage carries across into practical flavor, fragrance, and pigment synthesis, granting process control and cleaner separation in final steps.

    Other phenylpropanoids—such as ferulic acid, eugenol, or cinnamyl alcohol—offer different reactivity patterns. Customers wanting rapid oxidation or free-radical polymerization learn that coniferyl alcohol’s methoxy substitution modulates these pathways. Trials in our application labs routinely reveal lower side-product rates during peroxidase-driven biosynthetic mimics, sharpening results in both yield and analyte identification.

    Laboratory Insights and Lessons Over the Years

    Our teams have navigated every wrinkle—from solubility issues during large-volume synthesis to scale-up quirks that smaller labs often miss. We’ve learned that controlled temperature ramps and careful management of oxidative atmosphere protect coniferyl alcohol’s integrity. Routine attention keeps the product from forming resinous byproducts or losing activity before it reaches the customer.

    Long-term experience shows that product performance in the field correlates tightly with production discipline. Research teams testing new enzymes report higher reproducibility when coniferyl alcohol starts in a cleaned and inert-packed bottle. Anecdotal but recurring, we’ve even had flavor chemists say they build product launch timelines presuming our coniferyl alcohol arrives to spec, since reformulations due to off-product mean expensive test panels and lost market timing.

    Client Relationships and Ongoing Improvement

    Over the years, the conversation with customers has shifted from “What’s the price per kilogram?” to “How does your coniferyl alcohol perform in this challenging process?” We answer with documentation, technical data, and an openness to problem-solving. Clients facing new regulations come for detailed impurity profiles and get into discussions about crystal morphology. Others developing bio-based adhesives want supply reliability above all else, especially when governmental policies squeeze global logistics.

    We listen when research teams struggle to clean up reactions, and adjust our synthesis route if it improves the downstream process—even if it means taking a step back in the short term for a stronger long-term relationship. Trust, built from consistently clean and reliable chemistry, forms the basis for repeat business. Developers launching new papers, patents, or products give us early notice of tight deadlines, secure in knowing that close coordination remains possible.

    Moving Forward with Coniferyl Alcohol

    Pressure grows every year to push science along faster, with fewer errors and lower environmental impact. As regulations tighten and as research grows increasingly complex, coniferyl alcohol stands as a trusted backbone for chemists, engineers, and analysts who can’t afford surprise results. We remain dedicated to developing the product in response to field-tested needs, grounded in decades of experience and real-world feedback.

    Through pilot plant upgrades, laboratory investments, and ongoing staff training, we keep pace with the demands of modern, data-driven research. Supply reliability, technical transparency, and a willingness to collaborate shape our everyday approach. From early-stage R&D labs to high-throughput pilot production, we focus on making coniferyl alcohol a problem-solver instead of just another chemical in the catalog.

    Open communication and continuous improvement keep us connected to the needs of scientists and innovators worldwide. Ultimately, we see coniferyl alcohol as both a product and a dialogue—a partnership that invites new breakthroughs, supports rigorous research, and helps sustainable industries to flourish.