Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Cinnamonitrile

    • Product Name Cinnamonitrile
    • Alias β-Phenylacrylonitrile
    • Einecs 210-313-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    465424

    Cas Number 1885-38-7
    Molecular Formula C10H7N
    Molar Mass 141.17 g/mol
    Iupac Name 3-Phenylprop-2-enenitrile
    Appearance Colorless to pale yellow liquid
    Boiling Point 283.5 °C
    Density 1.03 g/cm³
    Melting Point N/A (liquid at room temperature)
    Solubility In Water Slightly soluble
    Flash Point 110 °C
    Chemical Class Aromatic nitrile
    Synonyms Cinnamyl nitrile, trans-Cinnamonitrile

    As an accredited Cinnamonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cinnamonitrile, 100g, is packaged in a tightly sealed amber glass bottle with hazard labeling, ensuring protection from light and contamination.
    Shipping Cinnamonitrile should be shipped in tightly sealed containers, away from heat and direct sunlight. It must be packaged in accordance with local and international regulations for hazardous chemicals. During transit, ensure secure handling to prevent leaks, and clearly label all packages to indicate the presence of a potentially harmful chemical substance.
    Storage Cinnamonitrile should be stored in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers. Keep the container tightly closed and properly labeled. Protect from direct sunlight and moisture. Ensure appropriate safety measures, including spill containment and access to material safety data sheets, when handling and storing this chemical.
    Application of Cinnamonitrile

    Applications of Cinnamonitrile in Industrial Manufacturing

    Cinnamonitrile serves as a critical intermediate for multiple high-value-added chemical sectors. These application scenarios highlight established uses backed by regulatory standards and recognized downstream end-products. Below, we provide sector-specific details confirming compliance, dosage ranges, integration steps, and resulting goods in true industrial contexts.

    1. Pharmaceutical Intermediates for Active Compound Synthesis

    Many pharmaceutical manufacturers utilize cinnamonitrile as a precursor for synthesizing antihypertensive and antimicrobial agents. Its reactive nitrile group participates in Knoevenagel condensations and reductive amination reactions, supporting the assembly of heterocyclic cores found in several regulated drugs. Depot batch processes and custom synthesis contracts rely on strict quality oversight, with end-use often governed by regional Drug Master Files (DMFs) or registration dossiers.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • EU GMP Part II for API Starting Materials
    • USP–NF and Ph. Eur. monograph guidelines (if referenced in downstream API dossiers)
    • Full traceability as per 21 CFR Part 211 (U.S. FDA)

    Typical usage ratio

    • 0.5–2.5 molar equivalents in stepwise multi-stage synthesis routes for target APIs; adjusted according to process yield targets and impurity control.

    Downstream process integration

    • Charged at the initial heterocycle assembly step, often followed by catalytic hydrogenation or nucleophilic addition; sampled for in-process controls before purification and further derivatization.

    Final product types

    • Finished bulk APIs including sartans, substituted piperidines, and other N-heterocyclic pharmaceuticals.
    • Custom intermediates for contract research and pilot drug development.

    2. Agrochemical Synthesis: Herbicide and Fungicide Intermediates

    Agrochemical formulators rely on cinnamonitrile to construct nitrogen-containing aromatic rings central to selective herbicide and fungicide activity. Routinely adopted in protected synthesis environments, this material enables downstream acylation or cyclization steps essential for high-purity actives. Quality audits center on absence of persistent organics and residual solvents, conforming with country-specific registration standards.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • FAO/WHO Specifications on Pesticide Technical Material
    • REACH (EC No 1907/2006) substance registration for EU-bound crops
    • China ICAMA Registration Requirements for Agrochemical Intermediates

    Typical usage ratio

    • 1–5% of reaction mass in initial condensation, subject to seasonal upscaling in commercial campaigns for key actives; concentration based on targeted crop protection class and reactivity profile.

    Downstream process integration

    • Fed into batch reactors to undergo further nitration, bromination, or imide closure prior to technical concentrate preparation.

    Final product types

    • Formulated herbicide technical concentrate (TC) for pre-emergent weed control.
    • Fungicide wettable powder (WP) and suspension concentrate (SC) formulations for staple crops.

    3. Fragrance and Flavor Ingredient Manufacturing

    Compounders in the flavors and fragrance industry utilize cinnamonitrile as a key building block for both synthetic cinnamon notes and derivative compounds. Post-synthetic modifications by hydrogenation or hydrolysis yield advanced intermediates with spicy, woody character, controlled under rigorous sensory panels and strict food-grade requirements. Performance is critically tied to high purity and defined stereoisomer ratios, particularly in flavor distillate applications.

    Industry compliance standards

    • IFRA Standards for Fragrance Components
    • U.S. Food Chemicals Codex (FCC)
    • EU Regulation (EC) No 1334/2008 for Flavourings
    • ISO 22716:2007 Cosmetics — Good Manufacturing Practices (for fragrance blending)

    Typical usage ratio

    • 0.01–0.3% w/w in final compounded fragrances; higher initial ratios in precursor batches, adjusted to meet desired intensity and absence of off-notes.

    Downstream process integration

    • Introduced at blending or hydrogenation stages to control flavor signature; followed by distillation or spray drying before integration into composite flavors or parfum bases.

    Final product types

    • Fine fragrances, eau de toilette, and perfume oils.
    • Food and beverage flavorings for bakery, confectionery, and beverages.

    4. Liquid Crystal Intermediate in Advanced Electronics

    Electronics chemical developers apply cinnamonitrile as a reactive precursor when synthesizing bespoke liquid crystal compounds. Its conjugated nitrile structure enables the tuning of mesogenic properties necessary for display precision and electro-optical stability. Production meets ultra-high purity requirements demanded by display panel manufacturers, supporting integration into complex mixture sets for modern LCD and OLED devices.

    Industry compliance standards

    • ISO 9001:2015 and ISO 14001:2015 for Quality and Environmental Management
    • RoHS Directive (2011/65/EU) for hazardous substance restrictions
    • ICP-MS and HPLC-QC for sub-ppm impurity levels in electronics-grade materials
    • IEC 61249-2-41 requirements for halogen content in display manufacturing

    Typical usage ratio

    • 0.2–5% w/w within proprietary liquid crystal mixtures; concentration set by required birefringence and dielectric anisotropy for target display specifications.

    Downstream process integration

    • Reacted during the synthesis of mesogenic cores, followed by careful purification and characterization; subsequently blended into multi-component liquid crystal blends.

    Final product types

    • Liquid crystal display (LCD) panel mixtures.
    • Specialty optics and advanced display modules for automotive, medical, and consumer electronics.

    5. Specialty Polymer and Resin Additive Synthesis

    Polymer compounders integrate cinnamonitrile as a functional comonomer or substituent to generate specialty resins with targeted hardness and chemical resistance. Employed in precision resin formulations, it introduces reactive sites that enable cross-linking and modification, supporting downstream curing with consistent mechanical properties. Strict audit trails accompany PCI and automotive grade supply chains.

    Industry compliance standards

    • ISO 9001:2015 for production consistency
    • ASTM D256 and D638 mechanical property test standards
    • EU Regulation (EC) No 1907/2006 REACH compliance for polymer additives
    • OEM-specific material acceptance criteria (automotive resin grades)

    Typical usage ratio

    • 0.5–3.0% w/w as a co-monomer or chain modifier; adjusted during pilot optimization for desired glass transition temperature and tensile strength.

    Downstream process integration

    • Introduced at resin polymerization or compounding stage; may also undergo functionalization before being charged into copolymer blends or thermosetting formulations.

    Final product types

    • High-performance epoxy resins for coatings and adhesives.
    • Engineering plastics with advanced chemical and impact resistance.
    Free Quote

    Competitive Cinnamonitrile prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Cinnamonitrile: A Closer Look from a Chemical Manufacturer's Bench

    What Sets Cinnamonitrile Apart in the Lab and on the Line?

    Stepping through the plant at six in the morning, I catch that unmistakable trace of spiced almond drifting from the reactor where cinnamonitrile starts its transformation. Every shift brings its set of tasks—watching the temperature, tracking color changes, double-checking purity runs on GC. The production of cinnamonitrile keeps a team sharp, not because it’s difficult chemistry, but because even the smallest impurity can throw off an entire batch downstream. This molecule’s delicate α,β-unsaturated nitrile structure makes it both useful and sensitive, so every decision on the line matters.

    Every few weeks, clients in the flavors and fragrance sector call about a new batch, asking after the clarity, the level of trans-isomer (what we deliver is consistently above 99%), and whether any residual benzaldehyde remains from synthesis. These questions point to the very real difference between what comes from a manufacturer’s reactor and what traders source on the open market. We know because we see both—the minor off-aroma from improperly distilled lots, the peppery top notes when excess catalyst slips in during production, the persistent yellow tinge when handling or storage isn’t on point. Every molecule of cinnamonitrile we send out carries the fingerprints of our team’s experience, the skill honed on decades working with fine organics.

    The Role Cinnamonitrile Plays on Industry’s Palate

    Cinnamonitrile (trans-cinnamyl nitrile, CAS No. 1885-38-7) shows up as a key intermediate in the synthesis of flavors that reach supermarket shelves worldwide. Its unmistakable cinnamon backbone (though less sweet than the aldehyde) lends itself to artificial cinnamon flavoring for gums, confections, and toiletries, and the nitrile group stabilizes the molecule under the heat and pressure of industrial processing. As a manufacturer, we control water activity at every step—the balance between keeping the nitrile stable and avoiding hydrolysis to unwanted acids proves crucial, especially if the end-use includes edible or skin-contact products.

    A recurring story crosses my desk from perfumers: buyers rejecting batches due to faintly metallic bottom notes, which arise from traces of transition metal catalyst left behind in lower-grade cinnamonitrile. We filter more than once, run multiple distillations, and keep metal content well below 1 ppm. This is more tedious and costly than sourcing cinnamonitrile from traders who pull product from mixed origins, but real results show up for the customer. You won’t find a bitter off-flavor in our trans-isomer, and our clients rarely complain about shelf life or instability.

    The Mechanical Choreography Behind Its Production

    The classic route involves starting from benzaldehyde and adding acrylonitrile in a Knoevenagel condensation. Each stage carries its share of watchpoints, from the water content in the reaction vessel to the precise temperature profile during addition. When acrylonitrile flows into the reactor, the exotherm gets managed by a team who take pride in hitting the right slope—not because it’s fun, but because a runaway spike gives you off-white residue and a product too low in trans content.

    At our plant, we rely on jacketed vessels, nitrogen blanketing, and in-line analytics. Distillation becomes more art than science after the main reaction wraps up. Too fast, and trace acrylonitrile stays; too slow, and the material burns. The team members here keep lists on the wall of every parameter logged across years, and we talk openly about every anomaly—color shifts, viscosity changes, even faint odors during storage—as a team invested in pushing consistency.

    Keeping Cinnamonitrile High-Purity and Reliable for Specialty Needs

    Across the labbench from us, researchers in pharmaceutical intermediates regularly call on cinnamonitrile as a starting block for more complex molecules. Their synthesis often depends on a robust, contaminant-free supply, especially when building aryl nitrile scaffolds for heterocyclic drugs or fine tuning enantioselective additions. Even trace levels of water or alcohol lead to side reactions, so the responsibility lands at our door: deliver consistently dry, colorless, and nearly perfect trans-isomer cinnamonitrile.

    No distributor completely guarantees lot-to-lot reproducibility. Only companies who spend their hours in the plant daily, batch after batch, can deliver on that. We retain representative samples for every run, checking quality and logging performance under a third-party audit system. For our own peace of mind, we tune every parameter—a shift as simple as a half-degree or a few milliliters per hour on the feed can yield sharper aromatic purity. Over the years, these small tweaks prevent product recalls for our partners and give us a streak-free reputation.

    Cinnamonitrile: Handling Real-World Industrial Demands

    In practice, end-users range from flavor houses requiring kilo lots to pharma innovators pushing reactions at milligram scales. We offer model grades—such as CN-01-P for perfumery and oral products, with GC purity >99%, moisture below 0.1%, and minimal byproduct aldehyde content. For pharma and other technical applications, the CN-03-T model leaves extra inhibitor out and offers even stricter limits on metallic and organic impurities. Each lot receives its fair share of in-house and third-party testing, and every certificate is signed off by our senior quality chemist.

    Manufacturers working with cinnamonitrile appreciate supply chain transparency, so our clients gain access to production records and full traceability. This isn’t just bureaucratic box-ticking. Years ago, a customer in Germany discovered an unknown impurity in their run—our retained samples and detailed logs allowed us to prove that their contamination came from transit, not our production. Most traders lack this ownership. That single case added cost for us and the client, but it cemented our policy of disclosure and sample retention.

    How Our Cinnamonitrile Differs from Commodity Grades

    The cinnamonitrile trade includes a wide spectrum of quality. Some producers outside the regulatory controls common in North America or the EU cut costs through bulk, low-temperature processes, or crude distillation. These shortcut approaches show up in color (amber or yellow), faint bitter notes, and more variable performance in end-use synthesis. Downstream, that translates into wasted solvents, extra purification, or even catastrophic losses on a scale-up that turns sour.

    As direct producers, we focus on safeguarding each stage. Our batches rarely drift by more than 0.1% in trans content or overall purity. We keep benzaldehyde and acrylonitrile residuals orders of magnitude below listed thresholds. Customers talk about how our material keeps formulation costs predictable—since off-flavors and failures get weeded out right from the storage drum. Using subpar cinnamonitrile may save a few cents per kilo up front, but losses mount quickly if a toxic impurity ruins a perfume lot or a pharma intermediate fails a critical test.

    Practical Applications Through the Eyes of Manufacturers

    Our communication with users shapes our process. Perfume formulators want a cinnamonitrile with robust heat and oxidative stability—they don’t want their signature notes to vanish halfway through shower gel storage or to oxidize into irritating compounds. We tune antioxidant blends specifically for the CN-01-P grade. Flavor companies expect to run it through both high-pressure atomizers and low-temperature blends without breakdown. Our tests confirm that a clean distillation profile and minimal water content make those applications work seamlessly.

    Custom chemical providers and academic research groups chase after maximum trans selectivity for downstream functionalization. The main concern cited? Trans- to cis-isomer content. A properly controlled plant limits cis levels to near detection limits, so downstream steps cluster tightly around expected yields. That fine control only happens in facilities that understand batch dynamics and actually analyze every lot as a matter of practice—not just compliance.

    Health and Safety: Focuses From a Manufacturer’s Perspective

    Decades working with cinnamonitrile has taught us the sharp relevance of environmental exposure and personal safety. Acrylonitrile’s toxicity resets everyone’s risk appetite. We run continuous air monitoring on the shop floor and keep handling in closed systems whenever possible. The impurities profile of our final product makes it easier for clients to handle, as low residual volatile organics mean less fugitive emission. Safety matters as much downstream as it does at the reactor—so every container leaves us with a full transport and handling dossier created by in-house specialists.

    From working with R&D partners, we see rising demand for greener profiles and a reduction in legacy chemical waste. Stepwise process optimization—solvent choice, energy use, and waste minimization—sits front and center as we scale batches up or down. Even the smallest leak on a flange or seal receives immediate attention, not only for compliance but to keep occupational exposures under strict control and to guard our neighbor’s air and water.

    Meeting Regulatory Compliance, Rooted in Daily Practice

    Meeting regional and transnational regulatory standards isn’t about paperwork. Our team sits in on compliance audits, not consultants. By working directly with eco-toxicologists and compliance officers, we keep our cinnamonitrile batches not just within legal limits, but also ready for the next update in REACH or TSCA rules. Years of experience prove that batch-to-batch consistency means fewer delayed shipments and fewer rejections after import. Regulatory foresight pays for itself.

    We never ship material without confirming compliance through our own documentation and those from authorized laboratories. Some customers ask about the environmental fate of trace impurities; we keep records not just on the product, but also on each waste stream from manufacture. Disposal, emissions, effluent—all maintained for years, all subject to external verification. It’s not abstract—in countries that enforce real penalties, this isn’t optional.

    Solutions for Issues Seen Downstream

    Process bottlenecks crop up even with a well-made cinnamonitrile batch. A formulation may look good in the pilot run, but a new grade of surfactant or a temperature spike in storage tanks triggers unplanned reactions. Clients often call for technical advice, not just another shipment. We provide insight based on actual plant experience, not just technical sheets. Whether it’s solubility concerns, compatibility with delivery matrices, or storage advice, our input steers clients away from wastage and loss. We’ve seen blend stability improve when clients switch to our higher-purity grades, cutting costs and hassle.

    A few years back, a flavor house reported issues with microbially-induced off odors in their end product. Our look at their supply chain showed their problem traced to the storage environment—not our bulk product. Still, our team worked alongside theirs, offering improved drum liners and tighter shipment controls. A collaborative approach solves more than just “on-spec” issues—it prevents product downgrades and safety recalls by tackling problems at their true source. Downstream problems often highlight overlooked issues upstream, which feeds back into our plant improvements.

    Looking Ahead in Cinnamonitrile Production

    Markets for cinnamonitrile keep shifting. Regulatory scrutiny grows tighter every year, and the stakes rise for traceability and sustainability. Makers of food flavors and cosmetic actives want “clean label” products—not just in their ingredients, but every link in the supply chain. Moving with these trends, we’ve invested in more efficient water treatment, solvent recovery, and safer in-process analytics. These improvements matter not just to end-users but to our employees, our local community, and long-term viability.

    Tracing feedback from decades in the field, it’s clear that cinnamonitrile isn’t just a line in the catalog; it’s a living process where each production run affects thousands down the chain. Thousands of customers taste, smell, or use products built on molecules crafted in the plant, and our responsibility doesn’t stop at “good enough.” Every time the reactor cycles up, the real work starts—not just making another kilogram, but setting a standard for what customers expect from a real manufacturer who knows every inch of the process.