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HS Code |
926817 |
| Chemical Name | Choline Citrate |
| Molecular Formula | C8H18NO8 |
| Molecular Weight | 271.23 g/mol |
| Appearance | White crystalline powder |
| Solubility | Highly soluble in water |
| Cas Number | 77-91-8 |
| Taste | Slightly salty and sour |
| Ph | Approximately 3.5–4.5 (1% solution in water) |
| Odor | Odorless |
| Storage Conditions | Store in a cool, dry place, tightly closed |
| Stability | Stable under recommended storage conditions |
| Uses | Nutritional supplement, source of choline |
| Melting Point | Decomposes before melting |
| Synonyms | 2-Hydroxyethyl(trimethyl)ammonium citrate |
| Source | Synthetic or plant-based |
As an accredited Choline Citrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White plastic bottle, 500 grams. Labeled “Choline Citrate,” with hazard symbols, batch number, expiry date, and manufacturer details. Sealed cap. |
| Shipping | Choline Citrate is shipped in tightly-sealed, clearly labeled containers to prevent moisture absorption and contamination. Packaging complies with relevant regulations, ensuring safe transit. The product is typically transported in fiber drums, plastic containers, or bags. It should be kept dry, cool, and away from incompatible substances during shipping and storage. |
| Storage | Choline Citrate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from direct sunlight and sources of heat or ignition. It should be kept away from incompatible substances such as strong oxidizing agents. Proper labeling and handling procedures must be followed to prevent contamination and ensure safety during storage. |
Applications of Choline Citrate in Industrial ManufacturingWe directly supply choline citrate to manufacturers across key downstream sectors where this raw material delivers tangible formulation and process advantages. This section outlines the principal industrial scenarios where choline citrate demonstrates consistent and compliant performance, based on established end-use standards and real-world production methods. 1. Infant Formula ProductionInfant formula manufacturers incorporate choline citrate as a critical nutrient source to support cognitive and physiological development in newborns and infants. Its high bioavailability, compared with inorganic forms, allows precise control over fortification levels without introducing chloride load. Quality departments monitor its integration to ensure batch uniformity and trace nutrient stability through shelf life evaluations, as required by infant formula regulators worldwide. Industry compliance standards
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2. Functional Food and Beverage FortificationFunctional beverage and meal-replacement manufacturers use choline citrate to deliver scientifically substantiated cognitive and metabolic health claims targeting adults and seniors. Its taste-neutral profile and high solubility allow seamless incorporation into ready-to-drink products, powdered drink mixes, nutrition bars, and meal shakes, while maintaining a clean label and declared ingredient transparency. Production teams track its addition to ensure bioactive integrity during pasteurization and shelf-life processing. Industry compliance standards
Typical usage ratio
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3. Animal Feed Premix ManufacturingIn the animal nutrition sector, choline citrate supplies a highly bioavailable form of choline to premix manufacturers, offering enhanced stability and lower risk of dusting compared to choline chloride. Formulators choose citrate salt versions in sensitive compounded feeds or where chloride content must be minimized, such as poultry starter diets and aquafeed for larval stages. Quality managers verify input conformity to ensure nutrient guarantee levels align with label claims and regulatory requirements. Industry compliance standards
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4. Parenteral Nutrition (IV Solutions) CompoundingCholine citrate acts as a controlled choline donor in the compounding of parenteral nutrition (PN) solutions, particularly in neonatal and critical care formulations where rapid and reliable systemic absorption is required and strict chloride load limits apply. Hospital and contract compounding pharmacies rely on pharmaceutical-grade material, conforming to injection safety standards, with each lot traceable back through full GMP production. Industry compliance standards
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5. Pharmaceutical Tablet and Capsule FormulationsPharmaceutical and nutraceutical factories use choline citrate as an active ingredient in cognitive health, liver support, and prenatal supplement products. Its low hygroscopicity compared to other choline sources allows stable direct compression and encapsulation even in high-speed production environments. Analytical QC tracks both content and stability in tablets and capsule fill for batch release and regulatory registration. Industry compliance standards
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6. Oral Liquid Nutraceutical ManufacturingProducers of oral liquid supplements incorporate choline citrate for fast-absorption choline delivery in adult and pediatric applications. Its high aqueous solubility allows for stable inclusion at label-declared doses, with integration parameters closely monitored to prevent precipitation or flavor imbalance during bottling and thermal stabilization. Regulatory compliance teams validate constituent levels to match supplement facts and ensure compliance with food supplement declarations. Industry compliance standards
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Competitive Choline Citrate prices that fit your budget—flexible terms and customized quotes for every order.
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Producing choline citrate carries more weight and responsibility than many outside the industry would guess. Our experience in the field has made one fact clear: not every choline salt suits every need, and the careful balance of choline with citric acid unlocks unique benefits that many manufacturers, feed formulators, and health supplement creators now depend on.
We manufacture choline citrate as a crystalline, highly water-soluble powder. The appearance matters. Consistency in particle size and color signals quality at every step of the process, from blending to final packaging. Inconsistent batches can ruin automatic dosing and complicate inspection. That’s why our technical team inspects every batch before release, not just relying on analytical tools but by using production experience to spot any deviations early. With every shipment, we build on direct feedback from our partners, making adjustments that stem from years spent on the floor with hands on the product.
Choline itself is one of those nutrients that frequently goes unrecognized until its absence causes headaches. In animal and human nutrition, choline provides crucial methyl groups for metabolic processes, helps with lipid transport, and supports nervous system health. In practical terms, farmers and feed manufacturers see direct benefits in growth rates, egg production, and litter quality when choline reaches proper levels in livestock diets. Less often discussed is the way choline draws value in personal healthcare and infant nutrition—where purity, safety, and reliable supply chain security play just as important a role as the nutritional science behind it.
Unlike choline chloride, commonly paired with chloride ions, choline citrate introduces a citrate group from citric acid. This composition translates into improved palatability and reduced corrosiveness, which manufacturers appreciate during equipment maintenance and process troubleshooting. Handling choline chloride can corrode feed mixers and metal bins, sometimes leading to production shutdowns or recurring costs for replacement parts. The less-aggressive citrate salt offers a practical answer where investors ask us about protecting their hardware, not just their animals or end customers.
We supply choline citrate in grades targeted for specific uses: nutritional supplements, food and beverage fortification, and animal feed. Though the chemical composition remains the same——choline hydrogen citrate, often written chemically as C8H20NO8——we differentiate by purity and moisture content, since these parameters tie directly to how our customers use the material. In our plant, we monitor both parameters throughout the process, drawing on thorough records and digital traceability systems that allow us to trace any batch through every stage of production.
One distinction with our choline citrate lies in its physical properties. The powder dissolves rapidly in water, forming a clear, neutral-tasting solution. Human supplement companies appreciate this, as it allows for easy blending into syrups, beverages, and tablet pre-mixes without leaving residue or clumping that would mar finished goods. In the animal nutrition sector, this easy dispersal means farmers can add choline citrate to water systems for flock or herd delivery, reducing mixing times and minimizing labor costs.
Our choline citrate meets established standards for heavy metals and microbial contamination. Every few months, we dedicate team meetings to reviewing these procedures, not out of regulatory obligation but because shortcomings here would directly affect our own brand’s reputation in key export markets. Over the years, we’ve seen the way a single contaminated batch can close off trade to entire regions, costing jobs and threatening long-standing partnerships. These experiences push us to maintain conservative limits, invest in qualified personnel, and double-check even when there isn’t an immediate crisis.
Chemical manufacturing doesn’t leave room for shortcuts. With choline citrate, the key stages run from the precise reaction of choline base with citric acid, through careful crystallization and gentle drying, to minimal exposure to environmental moisture. If humidity rises too high at any point, product can clump or degrade, leading to batch rejection. Our facility runs dehumidification across sensitive zones. The cost for environmental controls may seem high up front but we saw major reductions in customer complaints about caking once we committed to this approach.
Packing presents its own challenges. Unlike some “bulk” commodities, choline citrate packs for both food and feed applications. Some companies try for a one-size-fits-all packaging method, but our experience has shown that feedgrade and foodgrade customers want clear differentiation. Our food and nutraceutical clients expect packaging in double-lined, food-contact grade bags, while animal feed partners value strong, puncture-resistant sacks that stand up to rough handling. Listening directly to their needs has helped us avoid spoilage, off-odors, or breakage during shipping and storage.
Most customers entering the market for the first time find themselves comparing choline citrate with the more prevalent choline chloride or choline bitartrate. Here’s how these materials diverge in the realities of manufacturing and usage:
Over the past decade, choline citrate has found its way into an increasingly wide variety of applications. In industrial animal agriculture, it quickly became favored for applications in hatcheries and grow-out farms. Field trials in broiler chickens have shown less dust in feed bins and easier cleaning of water lines. With our steady supply chain, producers rely on regular deliveries, knowing batch-to-batch variation won’t surprise them.
In the personal health realm, our material enters direct compression tablets and liquid supplements. Supplement formulators highlight several advantages: our choline citrate does not cake during storage, meaning longer shelf life and easier large-scale mixing. Manufacturing teams, often under pressure to release new product lines on tight deadlines, have shared that the powder’s consistent moisture levels help them hit production targets for pressing tablets or bottling.
Mothers and pediatricians searching for safe forms of choline for infant formula prioritized purity and traceability, particularly in regions where food scandals have eroded trust. Our production records and open door auditing policy allow third-party verification for any client or regulator. We arrange yearly walkthroughs for representatives from partner companies as well as food safety officials, not just because we are required but because we have seen alliances form based on demonstrated transparency.
Anyone in manufacturing long enough develops a sense for pinpointing quality failures before they escalate. With choline citrate, our most critical time runs from drying to packing. Workers have found that even minor fluctuations in room humidity or slightly off-target particle size can result in material that cakes or fails to flow, complicating everything from automated filling to customer mixing downstream. For this reason, the team runs regular manual checks as a supplement to our real-time process controls, and we empower our operators to flag suspect batches with no penalty. Pride in product quality grows when team members see their vigilance rewarded with zero returns or complaints from loyal clients.
Counterfeit products and supply chain substitution threaten nearly every chemical manufacturer today. We have had customers return with stories of ‘off-spec’ choline citrate supplied by traders who didn’t know the difference between animal and food grade, leading to failed product launches or costly recalls. We engraved unique batch numbers and invisible security tags into our packaging not just to set us apart, but to make sure clients receive what they ordered, made by the team they trust.
Few appreciate the full range of stressors affecting the choline supply chain in recent years. Raw choline base and citric acid, both subject to global crop cycles, face pricing and availability swings. Anytime raw material prices jump, opportunistic traders swoop in, hoping to make quick deals at the expense of reliability. Our practice leans toward longer-term sourcing contracts with vetted suppliers. In years where yields dip, this keeps prices more stable for our end users.
Energy costs influence more of our bottom line than many anticipate. The drying steps for choline citrate eat significant electricity. We reinvested efficiency savings from improved air management and waste heat recovery back into training and quality monitoring. Unlike commodity players who seek only cost cuts, we found that a focus on durability and long-term trust pays dividends in repeat business.
Shipping pharmaceuticals and nutrients worldwide brings risks beyond just paperwork. Mishandling in transit, unexpected customs inspections, or delays at ports can degrade quality and sow uncertainty. Our experience with direct-to-client shipment tracking, frequent temperature checks, and responsive interventions means fewer surprises. Several clients told us that the difference between a successful launch and a failed one came down to how we managed short-notice logistical challenges.
Over time, our technical partnerships with leading food and feed scientists have driven steady improvements in choline citrate. In pilot projects for early-stage clinical nutrition companies, the flexibility of our manufacturing line let us supply specialized particle sizes or blends for research batches. We invited customer teams to run trials at our bench-scale mixers, sharing best practices learned from hundreds of industrial launches. Several innovations that stuck in the marketplace—such as multipurpose choline formulations—were born from hands-on sessions between our R&D chemists and customer process engineers.
We share technical data openly when customers face a challenge. Whether it’s solubility concerns in new beverage applications or compatibility with novel excipients, our support begins at the formulation stage. Several nutraceutical brands credit our extended support network for helping navigate tricky regulatory submissions in new countries or for adapting documentation as science and standards shift. Our factory personnel know the real-world importance of old-fashioned accessibility: direct phone support or video walkthroughs can solve small issues before they turn into recalls or line shutdowns.
Doing business as a direct manufacturer means more than just moving product. We keep our focus on reliability, safety, and transparent communication. Our direct engagement with regulatory agencies, multilayered quality systems, and real-time process monitoring provide security beyond numbers on a certificate. As scrutiny grows in the nutrition and feed additive fields, our philosophy ties back to doing things the right way, not just the most profitable way. Every batch of choline citrate leaving our facility reflects not just our skill but a working partnership with every customer who lives with the outcomes.
At every stage of growth in the choline citrate market, our experience has shown that small details—moisture, particle size, packaging choices, raw material consistency—accumulate into big outcomes. Companies that treat those details as afterthoughts find themselves chasing after problems that could have been prevented. By focusing on the details from start to finish, we deliver a product that stands up to real-world challenges—whether in a high-throughput animal feed operation in Brazil, a nutraceutical tablet line in Europe, or a clinical nutrition facility in Southeast Asia.
We see choline citrate continuing to grow as both industries and consumers search for nutrient forms that balance safety, ease of use, and dependability. Experience on the ground shows every improvement counts, and every problem solved earns lasting customer trust. As science uncovers more about the role of choline in health and productivity, and as equipment design evolves to accommodate new nutrient forms, our manufacturing approach will keep adapting, always rooted in lessons learned at the intersection of chemistry, practical usage, and customer feedback.