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HS Code |
623206 |
| Cas Number | 124-48-1 |
| Iupac Name | Chlorodibromomethane |
| Molecular Formula | CHBr2Cl |
| Molar Mass | 242.28 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Density | 2.522 g/cm³ |
| Melting Point | -57.2 °C |
| Boiling Point | 119.5 °C |
| Solubility In Water | 2.6 g/L (20 °C) |
| Vapor Pressure | 15.6 mmHg (25 °C) |
| Refractive Index | 1.545 (20 °C) |
| Flash Point | None (non-flammable) |
| Odor | Sweet, ether-like |
As an accredited Chlorodibromomethane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Chlorodibromomethane is packaged in a 500 mL amber glass bottle with a tightly sealed cap and clear hazard labeling. |
| Shipping | Chlorodibromomethane should be shipped in tightly sealed containers, kept cool, dry, and well-ventilated, away from heat, sparks, or open flames. It is classified as a hazardous material; handle with care and follow all pertinent regulations for transportation, including proper labeling and documentation. Use appropriate protective equipment during handling and shipping. |
| Storage | Chlorodibromomethane should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat sources, flames, and direct sunlight. It should be kept away from incompatible substances such as strong oxidizers. Storage areas must be equipped to prevent spillage and environmental contamination, with secondary containment recommended for larger quantities. Handle using appropriate chemical safety procedures. |
Applications of Chlorodibromomethane in Industrial ManufacturingAs a direct manufacturer, we supply chlorodibromomethane for highly specialized industrial markets. We focus exclusively on critical downstream applications where this compound delivers proven value, ensuring compliance, quality integration, and formulation precision throughout the process chain. The following examples reflect its real-world industrial roles across several key sectors. 1. Pharmaceutical Synthesis of Active IntermediatesPharmaceutical process developers use chlorodibromomethane in the controlled halogenation of specific organic intermediates, supporting the stepwise construction of complex molecular structures. Its selective reactivity allows for the targeted introduction of bromine and chlorine atoms in small molecule manufacture during active pharmaceutical ingredient (API) synthesis, particularly when alternative halogenation reagents show lower yield or greater byproduct formation. Consistent material purity and batch traceability are essential for protecting downstream production control. Industry compliance standards
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2. Laboratory Reagent for Bromination in Analytical ChemistryAnalytical laboratories rely on chlorodibromomethane as a standard brominating agent for specific GC/MS applications, especially when determining trace organic compounds in complex matrices. Its high purity and reliable handling make it suitable for quantitative derivatization, as required in environmental analysis or pharmaceutical residual testing. Laboratory managers select this reagent to maintain method validation consistency under regulated procedures. Industry compliance standards
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3. Synthesis of Agrochemical IntermediatesFormulators in crop protection chemical manufacturing introduce chlorodibromomethane as a halogen source in the synthesis of regulated pesticide intermediates. Its precision within bromomethylation and chlorination steps allows agrochemical synthesis engineers to produce intermediates with targeted substitution patterns, ensuring batch reproducibility and regulatory conformity for further processing into formulated end-use products. Industry compliance standards
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4. Disinfection By-Product Research and Utilities Process MonitoringProcess engineers and water research labs use chlorodibromomethane as a calibration standard and reference compound when monitoring regulated disinfection by-products (DBPs) in municipal water treatment operations. Its presence in controlled spiking studies supports validation of analytical instrumentation and ensures routine analysis aligns with international drinking water specifications—an essential requirement for public health and environmental safety teams. Industry compliance standards
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Manufacturing Chlorodibromomethane (CDBM) is no sideline operation; it calls for knowledge built on decades of chemical processing, respect for trace impurities, and a commitment to delivering what our end-users actually need. Each year, specialists in our facility work with metric tons of this colorless liquid, aiming for the narrow target set by regulatory and technical requirements—not only for purity, but for handling, traceability, and stability in shipment. Professionals in chemical and analytical fields recognize Chlorodibromomethane by its CAS number 124-48-1, known for a distinct set of features within the broader class of halomethanes. More importantly, the work put into refining, blending, and packaging CDBM at scale determines whether users in the field can trust it for their demanding applications.
Chlorodibromomethane rarely stays out of scientific reports about water analysis and method validation. Each batch rolling off our line is scrutinized with gas chromatography, usually showing assay values above 99.5% by weight. Our process consistently minimizes levels of related halogenated contaminants—difficult work since brominated byproducts can form during manufacturing steps if moisture, heat, or contact with lower-purity glassware intervene. Those who have worked closely in chemical plants know quality hinges on strict controls and a willingness to rework non-conforming material, not just paperwork. The slight, sweet odor, even at low concentrations, signals the right product but can't replace a certificate of analysis. Viscosity, density, and refractive index all get checked batch-by-batch. CDBM leaves our facility clear, with almost imperceptible color even in glass ampoules or drums, because any tint hints at heavier impurities.
Users familiar with EPA Method 551.1 or those in environmental labs immediately recognize CDBM as an essential standard for testing volatile organic compounds in drinking water and soils. It carries a reputation for robust chemical stability under standard laboratory fridge storage, meaning users don’t lose material even if a vial is kept for several weeks. Environmental technicians analyzing trihalomethanes turn to our CDBM as part of calibration routines, trusting that what’s stamped on the bottle matches what’s inside. Research labs in university settings as well as private industry sometimes use CDBM as a dense, non-flammable extraction solvent. The density of just under 2.5 g/cm³ makes it distinct; it easily sinks beneath aqueous phases without mixing, supporting reaction separations and trace enrichment. Nobody interested in reliable chromatography work skips over the importance of inert container linings—years of experience have shown trace reaction with steel caps or leaching from plastic can undermine even a careful analytical run.
Those who have worked hands-on in water quality fieldwork or analytical reference labs have faced headaches from less-than-optimal halomethanes: loss of sample integrity, evaporation from poorly sealed vials, or breakage during cold shipment. Planning shipments of Chlorodibromomethane involves more than just packing glass safely. Our production teams reinforce the need for cold-chain transport with humidity control. A single batch exposed to excess light or temperature swings can show elevated dibromoacetic acid byproducts, and experienced users will spot this by smell or through careful baseline measurement. Safety practices matter—a drop on the skin deserves immediate attention, and repeated inhalation in confined spaces is never taken lightly. Seasoned chemists know the difference between textbook handling and the discipline needed when managing halogenated chemicals at scale.
Among the halomethane family, Chlorodibromomethane stands out specifically because of the balance between its relatively moderate volatility and higher density, paired with a much lower reactivity compared to iodomethanes or chloroform. Workers in the plant observe that brominated halomethanes demand more stringent venting systems since their vapors can accumulate quickly in low-lying areas. Unlike tribromomethane (bromoform), which brings heavier environmental restrictions and higher persistence, CDBM usually breaks down more predictably under UV light, simplifying waste management steps at the user’s lab. Chloroform, which is still found in some extraction protocols, poses greater toxicity risks and carries tighter legal controls, making CDBM a preferred choice for those balancing performance and compliance. Our end-users bring up fewer pain points related to solvent loss or sample decomposition when CDBM comes from lot-verified production runs, a direct reflection on how supplier diligence translates into fewer failed analyses.
Raw material sourcing keeps changing as governments and upstream chemical producers set new restrictions. Experienced manufacturers know these pressures are not theory—they hit bottom lines and timelines. With global R&D spending favoring green chemistry, bromine stocks—sourced mainly by extraction from brine or as a byproduct of potash—run into periodic shortages when regulations or extraction costs spike. As a manufacturer, we’ve learned to hedge against these swings by securing long-term deals and diversifying regional supply bases. There’s no shortcut for process discipline: batch yields, residence time, and material flow all get constant review. Because CDBM shares manufacturing equipment with other halomethanes or specialty chemicals, rigorous cleaning and purge cycles become a necessity. We've refined these steps so that even trace quantities of polychlorinated byproducts fail to show up in routine gas chromatography checks. The challenge never lets up—delivering high-purity CDBM means adapting as regulations, analytical standards, and market expectations shift year to year.
Our production teams see firsthand the downstream effects when water authorities or remote testing sites lack access to pure reference compounds. Projects aimed at monitoring trihalomethane contamination in public water can grind to a halt with a missed delivery or inconsistent lot quality. Production teams carry out accelerated aging tests to ensure each shipment withstands seasonal temperature variation and long-haul transit, since some field outposts lack full refrigeration capability. We’ve fielded direct calls from public health specialists requesting guidance on storage, thawing, and vial integrity after rough handling. Those on the ground want more than a spec sheet—they want the confidence that comes from a relationship with the actual manufacturer, able to troubleshoot logistics and analytical pain points based on experience instead of guesswork.
Conversations with regulatory auditors and lab procurement managers shape how we design, fill, and seal Chlorodibromomethane lots. Documentation demands continue to grow: traceability from bromine drum to finished bottle, barcoding, and chain-of-custody checks. End-users testing for drinking water by EPA or EU regulatory standards look for more than purity sheets—they ask about historical contamination, batch history, and analytical support. Our staff participate in roundtable audits and proficiency tests, giving honest feedback on storage durability, evaporation rates, or headspace compatibility. The true value in our operation shows up in quieter metrics: lower customer complaint rates, fewer emergency replacement shipments, and feedback loops from field technicians, not just procurement officers.
Over the last twenty years, investment has gone into marrying legacy glassware techniques—hugely important for controlling small reaction runs—with modern computer-controlled reactors. Automation supports routine production, but seasoned operators remain critical for troubleshooting oddball result spikes, seasonal humidity swings, or the notorious “sticking phase” that sometimes plagues halomethane washes. Investing in leakproof seals, vacuum transfer equipment, and rigorous maintenance offers a real return: less off-spec product, safer working conditions, and fewer surprises for end-users. The scale of production never excuses a lapse; even one oxidized batch means a costly rerun and a wait for the next procurement cycle. Plant operations and R&D teams keep a running dialogue on how slight changes in reaction time, pH, or bromine quality produce measurable effects down the line, especially in tight-margin contract work.
Notifications start in the plant before any drums or ampoules depart: shippers reinforce boxes, insulate inner packaging, and document lot numbers to support global chemical databases. Once CDBM containers reach user sites, many teams discover the benefit of our proprietary liner construction—resistant to both volatilization and leaching, based on field experience with broken seals or frozen containers. We encourage direct feedback; queries about temperature excursions during customs clearance, minor cloudiness in returned vials, or alternate packaging formats often drive next-generation updates. Users in tropical or high-altitude locations especially note the importance of per-shipment cold-chain audits. Analytical teams often ask us about the best practices gleaned from years of shipping to challenging destinations.
Growing pressure from global agencies directs questions at both the environmental persistence and the occupational exposure risks related to Chlorodibromomethane. We have responded by pushing for greater process containment, routine monitoring of effluent streams, and in-house development of remediation procedures using synthetically derived reducing agents. What used to be simple drum storage now includes spill containment, secondary labeling, and compatibility risk reviews—borne out of on-site inspections and unexpected field incidents. Health and safety teams conduct walk-throughs after every major campaign, noting even small evaporative losses or packaging inconsistencies. No matter what the market demands, no lot of CDBM is ever released without documented compliance with both local and international chemical safety protocols.
Researchers in emerging fields—think atmospheric chemistry, laser spectroscopy, or advanced materials—sometimes push for higher purity or alternative stabilizer packages. We engage directly, discussing target impurity profiles, supply chain reliability, or shelf-life expectations. Years of direct engagement show that early communication on these points prevents costly redesigns. Researchers value openness about test results, including data on trace iodo- or unreacted brominated species. Even the smallest research purchases get tracked with the same rigor as bulk industrial shipments. Updates get circulated if a process tweak or improved detection method alters impurity identification. Chemists working out new analytical protocols benefit from talking with an actual manufacturer, not just a reseller quoting stock numbers from a catalog.
Incidents don’t announce themselves before they happen. Veteran operations staff remember the plant outage that resulted from a single misread pressure gauge mid-synthesis; production halted until the system cleared and every critical-control loop passed review. Learning from such events leads to real changes, like adding redundant pressure sensors, reinforced containment areas, and adjusted training for every new operator. Industry veterans know half-measures don’t last. We field questions on accident response and relay practical firsthand experience—no sanitized compliance boilerplate here—because it saves others from the same pitfalls. Open discussion on near-misses and manufacturing tweaks goes right back into SOP revisions and technician workshops, so both plant and field personnel see fewer disruptions and less downtime.
Technical support shouldn’t stop at shipment tracking numbers or warranty coverage. End-users sometimes uncover unreported incompatibilities with new glassware, changes in analytical column coatings, or persistent static charge with synthetic vial plugs. We encourage direct calls and open technical case notes, exchanging troubleshooting stories and best-practice recommendations without hiding behind generic support scripts. When new analytical regulations target previously unreported contaminants or storage conditions, updates move directly to user advisories, not buried in the fine print. Frontline lab technicians, QA auditors, and purchasing managers bring up unexpected technical hurdles, and direct manufacturer dialogue closes the gap faster than routed emails. This feedback cycle—documented, transparent, and routine—drives how we update formulations, introduce packaging tweaks, or redesign storage protocols, making a real difference downstream.
The past decade saw more collaboration with downstream R&D groups, instrument manufacturers, and reference labs, prompted by increasingly specific customer requirements. Modern analytical practices now demand even tighter impurity limits, better solvent compatibility, and longer shelf lives. Our plant teams collect and collate this feedback, running controlled experiments to validate new packaging films or container shapes. It isn’t simply about marketing “better” product; it’s about addressing pain points our customers discover in actual working conditions. This approach brought measurable drops in spoilage, fewer customer complaints, and more consistent lab performance. Trust builds on honesty, consistency, and a willingness to improve, not on empty claims.
Long experience in specialty chemical manufacturing reveals that reliability comes from genuine engagement, not just process know-how. Supplying Chlorodibromomethane involves steady investment in improved techniques, honest feedback from users, and careful attention to evolving market expectations. No marketing gloss can substitute for producer accountability—field failures, interruptions, or discrepancies get handled by people who know every facet of the production and delivery cycle. Over years, commitment to transparency, process discipline, and genuine two-way communication has fostered steady relationships with analytical labs, regulatory agencies, and specialty research teams. Users trust not just a molecule, but a process—and people—dedicated to delivering value with every batch.