Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Cetrimide

    • Product Name Cetrimide
    • Alias Cetramide
    • Einecs 200-175-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    331087

    Chemical Name Cetrimide
    Other Names Cetyltrimethylammonium bromide
    Cas Number 1119-97-7
    Molecular Formula C17H38BrN
    Molar Mass 364.39 g/mol
    Appearance White or almost white powder
    Solubility In Water Freely soluble
    Melting Point 242-250°C
    Ph Range 6.0 to 8.0 (1% aqueous solution)
    Application Antiseptic and disinfectant

    As an accredited Cetrimide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cetrimide is packaged in a white, opaque plastic bottle with a secure screw cap, labeled 500g, featuring safety and handling information.
    Shipping Cetrimide should be shipped in tightly sealed containers, protected from light, moisture, and heat. It must be clearly labeled and packaged according to local and international regulations for hazardous chemicals. Ensure proper documentation accompanies the shipment, and handle with care to prevent leaks or spills during transit.
    Storage Cetrimide should be stored in a tightly closed container, protected from light and moisture. Keep it at room temperature, ideally between 15°C and 30°C (59°F and 86°F). Store away from incompatible substances like acids and oxidizing agents. Ensure the storage area is well-ventilated, and keep the chemical out of reach of children and unauthorized personnel.
    Application of Cetrimide

    Applications of Cetrimide in Industrial Manufacturing

    Cetrimide serves as a widely recognized quaternary ammonium compound, engineered for professional use in multiple downstream industries requiring controlled antimicrobial action and surfactant properties. As a primary manufacturer, we maintain high batch-to-batch consistency to support reliable process integration at scale in regulated environments.

    1. Pharmaceutical Disinfectants and Antiseptics

    Pharmaceutical formulators incorporate Cetrimide primarily in topical and instrument disinfectant products, capitalizing on its effective bactericidal action against Gram-positive and Gram-negative organisms. Production adheres to precise documentation of formulation concentration to ensure both microbial efficacy and user safety, with strict segregation from actives sensitive to cationic surfactants. Quality assurance teams monitor both raw material identity and analytical conformance to pharmacopoeial requirements throughout blending, filtration, and packaging steps. Automated dosing controls maintain product uniformity at volume.

    Industry compliance standards

    • United States Pharmacopeia (USP) monograph
    • European Pharmacopoeia (Ph. Eur.)
    • Good Manufacturing Practice (GMP) guidelines
    • Shared equipment cleaning protocols (FDA 21 CFR 211.67)

    Typical usage ratio

    • 0.1%–1.0% by weight for bulk antiseptic solutions, adjusted based on spectrum testing
    • Lower end for skin disinfectants, higher end validated for surgical instrument immersion

    Downstream process integration

    • Formulated during aqueous solution phase in jacketed mixing vessels
    • Metered as a concentrated solution to final batch by peristaltic pumps
    • Filtration pre-filling to remove particulate contaminants
    • Finished product sterilized or filtered before bottling

    Final product types

    • Hospital-grade topical antiseptics
    • Preoperative skin cleaners
    • Instrument soaking solutions
    • Disinfectant wipes for clinical use

    2. Veterinary Antimicrobial Formulations

    Veterinary manufacturers utilize Cetrimide for broad-spectrum wound washes and animal care solutions. Their processes align with veterinary pharmacopoeias, ensuring the absence of cytotoxic byproducts when used in animal healthcare. Production teams dose the compound via inline blending units to guarantee even distribution and documented batch traceability. Formulators test every lot with in vitro microbial reduction and skin irritation assays, mandating rigorous in-process quality checks before packaging for veterinary clinics and farms.

    Industry compliance standards

    • Veterinary Pharmacopoeia of the People’s Republic of China (VPPRC)
    • British Veterinary Pharmacopoeia (BVP)
    • ISO 9001:2015-certified animal drug manufacturing
    • Hazard Analysis and Critical Control Point (HACCP) procedures for animal health products

    Typical usage ratio

    • 0.05%–0.5% for wound wash and animal shampoo solutions
    • Adjust based on species, animal weight, and veterinary toxicology guidelines

    Downstream process integration

    • Added post-purification to avoid interaction with nutrients or excipients
    • Combined with emollients and fragrance at cold-blending stage
    • Batch mixing with automated agitation in stainless steel tanks
    • Quality control sampling for microbial challenge testing

    Final product types

    • Veterinary skin cleansers
    • Livestock wound irrigation solutions
    • Antiseptic animal shampoos
    • Pre-surgical antiseptic sprays for pets

    3. Industrial Cleaning Compounds

    In industrial hygiene sector, cleaning compound manufacturers select Cetrimide for factory floor, equipment, and touch-surface disinfectants where strong surfactancy and microbial reduction are mandatory. Engineering and R&D departments routinely trial blends at varied hardness levels to validate foaming and wetting efficiency. Downstream processors employ recirculating tanks and automated dosing skids to maintain consistent Cetrimide dispersion, while in-house labs conduct ATP bioluminescence tests on finished batches to meet customer sanitation protocols.

    Industry compliance standards

    • OECD Guidelines for chemical safety in cleaning agents
    • EN 1276 for bactericidal activity of disinfectants
    • REACH registration for industrial chemicals
    • ISO 14001 for environmental management during production

    Typical usage ratio

    • 0.5%–2.0% in concentrated cleaning/degreasing fluids
    • Higher ratios required for high-organic-load environments

    Downstream process integration

    • Pre-blend with nonionic surfactants in high-shear mixers
    • Dosed via PLC-controlled pumps for continuous batch production
    • Quality verification by surface residue and microbial presence monitoring
    • Packaged into drums, canisters, or spray units based on end-user requirements

    Final product types

    • Floor and hard-surface disinfectant liquids
    • Equipment cleaning foams for food processing
    • Industrial sanitary wipes
    • Non-foaming machine detergents

    4. Personal Care and Cosmetic Preservative Systems

    Producers in haircare and skincare integrate Cetrimide primarily as a mild preservative and conditioning adjuvant in rinse-off formulations. R&D teams strictly control its inclusion during post-emulsification stages, maintaining clarity and stability in finished batches. Regulatory specialists ensure compliance with restricted use limits per global cosmetic directives, while in-process checks assess partitioning to avoid skin sensitivity and ensure shelf-life targets. Packaging lines test consistency at-scale, with full traceability back to raw stock acceptance.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 Cosmetic Products Regulation
    • U.S. FDA Title 21 CFR 720.4 (Cosmetics ingredient declaration)
    • ASEAN Cosmetic Directive
    • IFRA Code of Practice (incidental leave-on risk management)

    Typical usage ratio

    • 0.05%–0.2% for shampoos and conditioners
    • Up to 0.5% in specialty skin cleansers, strictly limited per regional regulations

    Downstream process integration

    • Added in controlled temperature conditions after emulsification
    • Homogenization in vacuum mixers to prevent air entrapment and ensure phase compatibility
    • Stability checked by accelerated aging and microbial preservation tests
    • Final filling operated under laminar flow to mitigate post-blend microbial ingress

    Final product types

    • Anti-dandruff shampoos
    • Conditioners for scalp care
    • Medicated liquid soaps
    • Preserved hair rinse systems

    5. Laboratory Microbiological Media Additives

    Microbiological diagnostics manufacturers employ Cetrimide to prepare selective agar and broth media for Pseudomonas aeruginosa and other non-fermenting Gram-negative bacteria. Cleanroom teams manage high-purity blending environments to prevent interference during colony isolation or susceptibility testing. Formulators calibrate inclusion rates precisely, avoiding inhibitory levels for target strains, with QA documenting every lot number and shelf-life for pharmaceutical or hospital microbiology labs. Technical support guides customer validation for sensitivity and selectivity as part of commercialization packages.

    Industry compliance standards

    • ISO 11133 for microbiological media preparation
    • CLSI M22 standards for QC of culture media
    • European Pharmacopoeia (Pseudomonas test for non-sterile products)
    • GLP (Good Laboratory Practice) documentation for traceability

    Typical usage ratio

    • 0.1–0.3 g/L in Cetrimide agar or broth formulations
    • Ratio fine-tuned based on strain and clinical testing application

    Downstream process integration

    • Blended post-sterilization once base media cools below 50°C, to prevent decomposition
    • Homogenized for even distribution, then dispensed in sterile Petri dishes or test tubes
    • Media batch coded and QC tested for selective growth and sensitivity
    • Packaged for hospital, pharmaceutical, and research laboratory clients

    Final product types

    • Cetrimide agar plates
    • Selectively inhibitory broths for clinical samples
    • Ready-to-use test tubes for pathogen screening
    • Clinical diagnostic panels for Gram-negative rods
    Free Quote

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    Certification & Compliance
    More Introduction

    Cetrimide: Consistent Quality for Reliable Applications

    Growing Demand Meets Reliable Consistency

    Years of careful production practice shape our Cetrimide into what modern customers actually rely on. In this industry, experience shows that success follows those who never compromise on purity and batch uniformity. From our own manufacturing lines, we commit to that kind of discipline, because even small lapses in process create cascading problems for users down the supply chain. Whether poured into a hospital bottle or blended in a pharmaceutical batch, Cetrimide must deliver consistent results.

    Cetrimide USP: What We Bring to the Table

    Our Cetrimide carries clear-cut specifications because real-world work calls for predictability. On every production run, our team tests for appearance, assay, pH range, and moisture content. The model primarily produced is standard grade, crystalline, and meets widely recognized pharmacopeial standards, including USP. You can trust the white to off-white free-flowing powder to dissolve without fuss, leaving no residue that interferes in formulations.

    Every shipment undergoes identity confirmation using IR spectroscopy, so trace differences never slip by. Close control over ammonium salts and related impurities limits off-odors or variable reactivity, two issues our technical customers often flag from competitors’ off-spec material. That close attention comes from actual past experience—customers return when their process yields don’t dip from batch to batch, and we guard that with in-process checkpoints, not just final batch tests.

    Proven Outcomes in Numerous Use Cases

    Our own facility’s batch records show who relies most on Cetrimide: hospitals, clinics, pharmaceutical formulators, and cosmetics manufacturers. The bulk goes into antiseptic creams, mouthwashes, and surgical scrubs due to Cetrimide’s broad antimicrobial action against Gram-positive and Gram-negative bacteria. Formulation scientists want a surfactant-dispersant that doesn’t push up irritation levels or interact with active pharmaceutical agents. Years of experience supplying major domestic and export customers taught us which impurity levels trigger failed tests or customer complaints—they rarely result from our in-house product, because we screen for those from the start.

    In pharmaceutical environments, even minor contaminants impact shelf stability and compliance. This is why the Cetrimide we supply goes through moisture balancing to keep hygroscopicity controlled. Excess water content triggers caking, makes powders sticky, and can compromise finished product stability—if you’ve ever handled a stuck-together lot on the packing line, you know how costly that can get. Careful drying and moisture testing at every critical point prevents those headaches.

    Laboratories who rely on Cetrimide in diagnostic media don’t want false positives or fluctuating growth suppression profiles. The antimicrobial action should come from the intended concentration, not unknown trace byproducts or careless mixing. Our standardized blending and mixing tanks make sure that each shipment delivers the declared percentage of active quaternary ammonium compound—not just on the COA, but verified in real-use conditions.

    Real Differences from Other Products—Built Through Practice

    Users often compare Cetrimide to other quaternary ammonium compounds—sometimes Benzalkonium Chloride or Chlorhexidine. The differences run far deeper than just label claims. Benzalkonium Chloride stirs faster in water, but our own R&D testing shows Cetrimide outperforms it in maintaining clarity and microbial kill in buffered personal care products. Our long-term customers in cosmetics prefer Cetrimide when product feel and clarity matter most; it creates a more agreeable texture and scent, especially after storage under variable conditions.

    Chlorhexidine serves as a strong alternative in surgical scrubs, but many formulators report it creates brown precipitates over time and restricts coloring options. By contrast, our Cetrimide batches, standardized for color and absence of heavy metals, create a transparent base for tinted creams and gels. This advantage comes directly from process-level controls backed with real-world technical support—we solve issues on the line, not only in the lab.

    Shelf-life matters, too. Shelf-life extension tests in our own storage rooms show that Cetrimide, when produced and handled with attention to pH and moisture, maintains antimicrobial activity well beyond the minimum declared period. This reliability is specifically relevant for hospitals that rotate stock on a quarterly basis, where expired antiseptics can’t be tolerated. Each shipment leaves with data-backed stability results, not broad claims—because we’ve watched what happens when hospitals run short from a spoiled lot.

    Specifics from Our Production Floor—No Rushed Shortcuts

    Every stage in our facility targets risk points we’ve found in years of large-batch production. Raw material suppliers must pass regular audits; if their certificate of analysis misses our requirements, we investigate before any goods enter our blending tanks. Staff check for color, clarity, and foreign odor. This approach prevents the headaches that come from troubleshooting flake-outs six months after delivery.

    Mixing and crystallization run at controlled temperatures—a step we dialed in through trial and error, to prevent caking and color drift that used to occur with old equipment. Automated drying and sieving deliver a fine grade, so your finished product flows smoothly into powder fillers or dissolves fast for liquid batching.

    Microbial control inside our plant doesn’t just happen in the cleanrooms; it starts in how warehouses are organized, airflow patterns, and segregation of high-allergen ingredients from quaternary ammonium products. These controls matter most in the rainy season, when ambient humidity rises and fungistatic activity needs extra assurance. Only regularly recalibrated equipment makes the difference between a flawless batch and one that generates unnecessary customer support calls.

    Practical Applications Outside Medicine

    Cetrimide’s use stretches well beyond medical antiseptics. Formulators in veterinary care and agriculture favor its rapid action against mastitis-causing bacteria or as a cleaning aid in dairies. Our technical team fields frequent requests for application advice in veterinary wound cleansers; Cetrimide delivers antimicrobial coverage while causing less stinging or tissue irritation compared to older iodine or phenol-based alternatives.

    Detergent manufacturers come to us seeking a cationic surfactant that pairs with anionic and nonionic systems, especially in fabric conditioners and stain removal prewashes. During scale-up, our process team demonstrates how to integrate Cetrimide powder into continuous production lines without hazardous dust plumes. Handling guidelines and technical guidance come straight from actual production troubleshooting, not just from the literature.

    Our R&D work shows that Cetrimide’s cationic base improves dispersibility of active agents in water–alcohol blends, vital in hand sanitizers and topical sprays. Compared to alternative cationics, its skin feel rates better with our in-house testing group, who provide feedback after repeated washing cycles. For wound wash solutions, its low irritancy matches with published clinical data and matches our internal observations after years of providing samples to hospitals and clinics.

    Lessons Learned From User Feedback

    Clients prefer predictable products over flashy marketing. Sites that use our Cetrimide have shared how deviations in granule size or trace ionic impurities led to batch rejections—sometimes costing more than the original raw material order. Because of these frank reports, we tightened controls over granule sizing and overlay grading to more closely match process needs. Our batch records track each adjustment, and we push these lessons back into production meetings.

    Pharmaceutical and cosmetic clients demand traceability for regulatory audits. They want to see a clear lineage from raw input to final packaging, not just a signed COA. Our production tracking not only meets those expectations but allows us to resolve queries fast if an issue appears. Technical files are never buried in the back office; each batch’s critical data gets logged electronically and archived by trained staff.

    Routine customer audits keep our practices honest. Visitors walk through mixing, drying, and sampling stations, reviewing cleaning records and environmental logs. Their questions often turn up small details that matter, such as filter mesh size or packaging liner thickness. These encounters develop trust, since they can see where their product comes from—not a distant warehouse, but a facility dedicated to operational transparency.

    Improvements Guided by Experience, Not Only Data

    We learned over many seasons that paperwork rarely solves the root problem; hands-on process changes do. Years ago, powder caking during monsoon season sometimes slowed output. Instead of just raising quality specs, we improved plant climate control to hold humidity below target levels. Production staff provided suggestions that led to better sealed packaging with double linings—a real upgrade that cut down complaints from bulk buyers in humid regions.

    Feedback from the field led to upgraded documentation: standardized batch protocols now include color, particle size, and flow properties data for each production run. Auditors, both local and international, appreciate that our records match what they find during floor walkthroughs. This reduces tension during regulatory reviews and speeds up client product release checks.

    Last year, changes in regulatory requirements for impurity profiles led us to refine our in-process sampling and detection methods, not just at the final stage. This allowed a quicker response to any sign of impurity drift, which we caught early in a single batch before it went to packing. That capacity for improvement comes only from experience on the manufacturing floor and fast communication between QA and production teams.

    Safety in Handling: Real-World Guidance

    In any manufacturing facility, practical safety procedures matter more than overlong safety sheets. Cetrimide isn’t classified as hazardous for transport, but our crew follows strict guidelines to prevent skin and eye contact—direct experience taught us that minor exposure, especially on open wounds, causes discomfort. All material handlers receive refresher training and know where eye wash and hand rinse stations sit on the production floor.

    Spill response plans don’t exist just for compliance. They come from real incidents—minor, but illuminating—where small, unnoticed spills created slippery patches. Updated cleanliness checklists now include extra sweeps and spot checks around blending zones. Packed shipments use tamper-evident closures to build another layer of assurance between our plant and the client’s warehouse, which cuts down on supply chain headaches and keeps product usable to the last scooped gram.

    Environmental Considerations Shaping Operations

    Communities and regulators pay attention to effluent, so our plant runs regular audits on wastewater for quaternary ammonium levels. Trade effluent handling systems neutralize Cetrimide before release, using chemical precipitation and filtration—learned the hard way after an early incident led to a regulatory fine. Those lessons led to solid environmental protocols, shared openly with local authorities and clients who want proof their supply partners play by the rules.

    Sourcing Cetrimide ingredients with minimized environmental footprint makes a difference. We work with upstream suppliers to choose inputs with trackable, responsible sourcing histories. Our own packaging materials moved to more recyclable outer drums and carton liners after a series of customer discussions about waste volumes, especially from export markets where disposal options may be limited.

    Meeting Market Shifts Through In-House R&D

    Formulators push for more creative end uses. We channel their requests into trial batches—personal care wipes, pet cleansers, agricultural sprays, and more. Each new project draws on our staff’s collected experience with blending, emulsification, and dispersibility challenges, especially as regulatory and customer expectations keep rising.

    Cross-functional teams—drawn from production, QA, packaging, and R&D—bring fresh solutions when routine tweaks don’t cut it. For example, during the recent global push for lower residuals in finished biocidal products, the technical team reformulated Cetrimide’s secondary processing to further reduce ionic byproduct residues. This not only addressed new compliance benchmarks but brought in a wave of interest from customers who previously hesitated to switch suppliers.

    Test batches often go out to loyal customers for live feedback. In one recent cycle, a major cosmetic formulator described better lather and softer after-feel after using an upgraded lot. Those insights move directly into full-scale production, closing the loop between customer and plant floor.

    Forward Focus: The Value of Adaptable Manufacturing

    Markets change, and standards keep rising. We prepare for tougher regulations and new end-use profiles. The flexibility to adapt quickly—by internal agreement, not months of paperwork—means our Cetrimide stays competitive and safe. Technical staff meet quarterly to exchange ideas and review data from customer returns, audit trails, and field complaints. This approach keeps improvements continuous and practical.

    Adapting plant practices to meet tighter regulatory thresholds made sense when new requirements rolled out for heavy metals in the product matrix. Rapid, plant-wide implementation occurred because every line worker contributes experience and solutions. This team culture ensures each container meets agreed standards, while allowing room for incremental improvement in purity and performance.

    Supply chain resilience also requires attention. Several years ago, our region faced raw material shortages due to disrupted transport. That episode taught us to pre-qualify not only A-list suppliers, but fallback sources as well, maintaining buffer stocks even in quiet months. These practices shield regular customers from price volatility and unfulfilled shipments, which can affect downstream businesses and, in medical settings, even patient care.

    Without Distributors—Direct Manufacturer Relationships Matter

    Direct line between buyer and producer is more than a slogan. In our experience, the toughest technical questions, urgent packing fixes, and custom compliance audits only get solved in real time by direct communication. Since we control every section of the Cetrimide supply chain—from sourcing to delivery—we provide answers that distributors often cannot. Regular clients value quick response to sample requests and technical clarifications.

    Maintaining that direct connection prevents common problems such as product substitutions, batch blending, and confusing labeling that sometimes occur in layered distribution channels. Customers return not just for product, but for consultation, process optimization, and practical troubleshooting. Our technical support draws on full batch histories and development records, not generic answers.

    Relying on Real-World Experience

    Years in the field shape how we make and support Cetrimide, not marketing copy or lab claims. By connecting the dots between customer concerns, handling improvements, and ongoing technical tweaks, we deliver a product that keeps pace with changing needs and raised expectations. Each batch bears the weight of years of cumulative feedback and the continuous drive toward practical excellence in manufacturing.