Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

(+)-Camphanic Acid Chloride

    • Product Name (+)-Camphanic Acid Chloride
    • Alias (+)-Camphanyl chloride
    • Einecs 205-940-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    996487

    Product Name (+)-Camphanic Acid Chloride
    Cas Number 1461-72-9
    Molecular Formula C10H15ClO2
    Molecular Weight 202.68 g/mol
    Appearance White to off-white solid
    Melting Point 69-71°C
    Boiling Point 120-122°C at 10 mmHg
    Specific Rotation +44° (c=1, CHCl3)
    Density 1.144 g/cm³
    Solubility Reacts with water, soluble in organic solvents
    Purity Typically ≥98%
    Synonyms Endo-(+)-Borneol-10-carbonyl chloride
    Iupac Name (1R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2-carbonyl chloride
    Storage Conditions Store under inert atmosphere, at 2-8°C
    Refractive Index n20/D 1.483

    As an accredited (+)-Camphanic Acid Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing (+)-Camphanic Acid Chloride, 5g, packaged in an amber glass bottle with screw cap, featuring hazard and chemical identification labels.
    Shipping (+)-Camphanic Acid Chloride is shipped in tightly sealed containers under cool, dry conditions, protected from moisture and light. It is packaged according to hazardous material regulations, with appropriate labeling for corrosive substances. Transportation follows local and international safety guidelines to ensure safe handling and delivery to the recipient.
    Storage (+)-Camphanic Acid Chloride should be stored in a tightly sealed container under an inert atmosphere, such as nitrogen or argon, to prevent hydrolysis and degradation. Keep it in a cool, dry place away from moisture, light, and incompatible substances such as strong bases and oxidizers. Recommended storage is at 2–8 °C and within a well-ventilated chemical storage cabinet.
    Application of (+)-Camphanic Acid Chloride

    Applications of (+)-Camphanic Acid Chloride in Industrial Manufacturing

    As a direct manufacturer specializing in high-purity (+)-Camphanic Acid Chloride, we supply this chiral reagent to a focused range of downstream industries with proven, compliant applications. We have outlined key application scenarios below, detailing relevant regulatory guidance, dosage strategies, integration in modern manufacturing, and the types of products our industrial clients produce using this material.

    1. Chiral Auxiliary in Pharmaceutical API Synthesis

    Pharmaceutical developers and contract synthesis companies rely on (+)-Camphanic Acid Chloride as an enantiomerically pure chiral auxiliary in the asymmetric synthesis routes for active pharmaceutical ingredients, especially during the preparation of intermediates for anti-infective or anticancer agents. The compound is introduced early in the route, conferring critical stereoselectivity during key transformations, followed by its later removal to afford enantioenriched intermediates. The downstream process and compliance documentation must reflect the stringent controls required at every stage of cGMP manufacturing.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • U.S. FDA 21 CFR Part 210/211 (cGMP for Finished Pharmaceuticals)
    • European Pharmacopoeia monographs relating to chiral precursors

    Typical usage ratio

    • Usage commonly ranges from 1.1 to 1.3 molar equivalents per target substrate, depending on substrate reactivity and scale, with further adjustments based on stereoselectivity requirements and target API specifications.

    Downstream process integration

    • Introduced at the chiral auxiliary installation step immediately after precursor functionalization, followed by separation and recovery after completion of key stereocontrolled bond formations such as aldol, Michael, or Mannich reactions.

    Final product types

    • Enantiopure drug intermediates for cephalosporin antibiotics
    • Stereodefined intermediates for oncology molecules
    • Final APIs where chiral purity is mandated

    2. Stereoselective Synthesis of Agrochemical Intermediates

    Manufacturers in the agrochemical industry integrate (+)-Camphanic Acid Chloride for the preparation of chiral intermediates used in crop protection agents, especially for selective herbicides and insecticides. These processes demand enantiocontrol during esterification or amide-bond formation steps, ensuring agrochemical actives achieve the necessary bioactivity and regulatory profile. This step is crucial for meeting environmental and product safety registrations worldwide.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems for Agrochemical Production
    • FAO Specification on Technical Grade Active Ingredients
    • EPA Pesticide Registration Standard (U.S.)

    Typical usage ratio

    • Addition rates of 1 to 1.2 molar equivalents per substrate are typical, although ratios are fine-tuned depending on the targeted selectivity and scale-up efficiency.

    Downstream process integration

    • Utilized in the stereoselective blocking group installation preceding key transformations in heterocyclic or ester-forming steps, subsequently removed after final chiral integrity assessment prior to downstream active formulation.

    Final product types

    • Chiral intermediates for sulfonylurea and triazole herbicides
    • Enantioenriched precursors for pyrethroid insecticides
    • Building blocks for regulatory-compliant fungicide actives

    3. Chiral Resolving Agents in Fine Chemical Research and Production

    Fine chemical manufacturers and research laboratories utilize (+)-Camphanic Acid Chloride as a chiral resolving agent in the preparation and isolation of optically pure compounds, particularly during salt or ester formation to separate racemic mixtures by crystallization or chromatography. This step is essential for the production of specialty compounds, flavors, and fragrance intermediates that require optical purity, as well as for analytical standards in laboratories.

    Industry compliance standards

    • ISO 17025:2017 for Laboratory Testing and Calibration
    • REACH SVHC and GHS labeling for specialty chemicals in the EU
    • IFRA Standards for Fragrance Ingredient Handling

    Typical usage ratio

    • Generally 1:1 molar ratio with racemic base compound; excess may be applied to drive crystallization where separation efficiency is critical for yield or purity.

    Downstream process integration

    • Introduced to racemic mixtures during resolving agent-ester or amide formation steps, followed by selective crystallization and chromatographic purification to obtain the desired enantiomer, then hydrolysis to recover the pure product.

    Final product types

    • Optically pure specialty amines and acids
    • Stereopure intermediates for advanced research compounds
    • Precursors for high-value aroma chemicals

    4. Synthesis of Chiral Polymers and Functional Materials

    Producers of advanced functional materials and chiral polymers apply (+)-Camphanic Acid Chloride as a stereochemical imprinting agent during polymerization or the synthesis of monomer units. The targeted introduction of defined chirality enhances the performance of components in optical, electronic, or asymmetric catalysis applications. Process controllers and R&D teams closely monitor this integration, as control over polymer tacticity and chiral center configurations directly impacts downstream applications in optoelectronics and separation membranes.

    Industry compliance standards

    • ISO 9001:2015 for Polymer and Advanced Material Production
    • RoHS Directive for Electrical and Electronic Equipment (EU)
    • ASTM D638 for Polymer Mechanical Property Testing

    Typical usage ratio

    • Standard loading is 0.5 to 1.0 equivalents per polymerizable monomer, tailored by desired chiral induction strength and end-use mechanical or optical property targets.

    Downstream process integration

    • Incorporated during monomer modification or pre-polymerization activation, removed or retained depending on post-polymerization treatment and application requirements.

    Final product types

    • Chiral stationary phases for chromatography
    • Specialty polymer membranes for enantioselective separations
    • Chiral optoelectronic device components
    Free Quote

    Competitive (+)-Camphanic Acid Chloride prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    (+)-Camphanic Acid Chloride: Direct from Factory

    A Closer Look at Camphanic Acid Chloride

    Manufacturing specialty chemicals brings a unique perspective to understanding the journey from raw material sourcing to precise molecular transformations. At our facility, (+)-Camphanic acid chloride stands out as a refined specialty intermediate synthesized from natural camphor derivatives. Decades of hands-on production and process improvement have led to a product recognized for its consistency and performance in pharmaceutical, agrochemical, and fine chemical applications. From the plant floor to the final packaging line, every batch draws on this history of refinement that comes with doing the work ourselves—without dependence on reselling third-party inventories or transient bulk stocks.

    Model and Specifications Rooted in Manufacturing Experience

    Unlike generics that change hands without oversight, our specification process roots itself in on-site experience. The colorless to slightly pale liquid is produced under tightly controlled conditions, with every step logged and traced. Purity levels routinely reach >98% by HPLC, minimizing unwanted byproducts that can complicate downstream transformations. The specific optical rotation, following [α]D yields, consistently stays within a predefined narrow window, validated each batch with in-house chiral chromatography methods. Moisture levels and acid values are monitored at multiple points using Karl Fischer and potentiometric titration; solvents and residual reagents are controlled below industry detection limits. Every technical tweak in synthesis and purification reflects years of scale-up optimization rather than third-party simplification. This close oversight ensures not only a carefully curated chemical profile but also the reliability needed for regulated industries.

    Application Examples—From Building Blocks to End-Use Synthesis

    The utility of (+)-Camphanic acid chloride starts with its role as a chiral auxiliary and protecting group, particularly valued for its sterically demanding camphanyl moiety. Our chemists have worked alongside innovators in peptide, carbohydrate, and nucleoside modifications where the configuration integrity can define the nature of final biological activity. In asymmetric synthesis, it finds repeated use to induce stereoselectivity in target molecule construction—helping guide difficult reactions toward high enantiomeric excesses. Processing teams frequently leverage it in esterification and amidation reactions that transform high-value intermediates. When a contract client seeks scale-up support for a new active pharmaceutical ingredient, our bench-to-bulk knowledge with camphanic acid chloride often makes the difference. The transition from research to consistent commercial output relies on having access to a trustworthy source—something trading companies can’t easily deliver.

    This acid chloride’s unique structure, based on naturally occurring camphor, also makes it especially attractive where renewable or biobased sourcing enters the equation. As regulatory pressure increases on synthetic chemical inputs, the fact we manage raw material traceability matters more each year. Seasonality in camphor supply, variation in natural product composition, and environmental concerns about waste handling all filter directly into our decisions on production planning and process design. The practical know-how gained in handling, storage, and downstream processing allows us to suggest optimal conditions for maintaining reactivity—right down to preferred solvents, temperature, and handling precautions. Such specificity only surfaces on the factory floor, and we are always ready to share practical knowledge with customers integrating this product into sensitive processes.

    Comparing with Other Acid Chlorides—Key Production Insights

    Many laboratory and industrial users compare camphanic acid chloride against general-purpose acid chlorides like acetyl, benzoyl, or pivaloyl chloride when they evaluate new synthetic strategies. The real distinctions come out in production, not just paperwork: the camphanic derivative carries pronounced steric bulk, delivering exceptional selectivity for challenging chemistries. Our team’s first-hand observations highlight how its reactivity profile avoids the over-activation or side reactions sometimes caused by less hindered analogues. The optical activity imparts a layer of control critical to modern chiral chemistry, while the crystalline or oil-like form encourages safer, less volatile operation than more reactive or fume-prone options.

    From a chemical plant’s view, handling inorganic chlorides and hydrogen chloride gas often causes corrosion, off-gassing, and operator concerns. Over years of continuous production, we modified reactor design and ventilation strategy to safely accommodate camphanic acid chloride’s unique volatility and reactive characteristics. This led to improved yield, more reliable in-process monitoring, and process waste minimization. Smaller operations or traders lacking such background may overlook these process nuances, risking inconsistent product performance and safety hazards. Our people take personal pride in supporting customer technical teams with this sort of deep practical advice—because we see the results of these small decisions every day.

    Quality Takes More Than Certificates

    Industry certifications carry importance, but our production staff puts trust in continuous in-process checks and seasoned quality assurance. Each container of camphanic acid chloride is tagged with real batch production data, stability information, and retention samples pulled from every run. We test not just the active ingredient, but also closely monitor for any trace contaminants—especially organic acids, solvent residues, or hydrolysis products known to degrade product usability and safety. Instead of relying solely on post-shipment complaint resolution, we investigate and resolve subtle changes in starting material, equipment clean-out, or local humidity well before they could affect final delivery. This investment into hands-on quality management, guided by direct responsibility, sets our product apart in practice, not just specification.

    Feedback from our clients shapes our improvement cycle. Medicinal chemists developing new lead compounds share insights about reactivity in non-standard solvents and cross-coupling reactions. Process engineers running multikilogram reactions note packaging preferences and flow rates suited to automated feeding. Pharmaceutical QA teams with heightened regulatory demands outline proof points for traceability and stability. Only by integrating these real-world accounts do we evolve beyond static data sheets—offering both documentation and deep operational support that meets today’s industry expectations and anticipates tomorrow’s hurdles. This feedback loop forms a foundation for consistent, reliable supply chains, especially when market conditions shift or new applications emerge unexpectedly.

    Process Safety and Practical Storage

    No chemical with acid chloride functionality gets managed casually. Our facility layout, material transfer procedures, and waste gas abatement all reflect experience accumulated through countless batches of camphanic acid chloride. We understand the difference between theoretical hazard controls and those that work after years of repeated operation under all seasons. Packaging choices reflect what works against moisture ingress, light exposure, and trace acid formation—mapped against shelf-life studies performed in tandem with our internal and client-run stability trials. Customers scaling up new routes or adjusting storage strategies benefit from these lessons; often, a conversation with a process operator saves days of troubleshooting and prevents costly mishaps. Such value arises only from living the production process—not from reading regulatory checklists.

    Environmental Responsibility Is Grounded in Practice

    The global push for greener chemistry becomes tangible in a facility-minded approach. Camphanic acid chloride’s heritage as a derivative of biobased camphor means our production team pays special attention to solvent recycling, byproduct valorization, and water treatment. Over time, process intensification reduced our use of auxiliary chemicals and streamlined energy consumption. We monitor both solid and liquid waste streams, selecting handling options guided by practical outcomes and compliance with local and international environmental standards. Rather than marketing hype, our sustainability initiatives live in the audits performed by both our own team and visiting partner companies—closing the loop between environmental theory and daily plant operation.

    Customers working in environmentally conscious industries often share their audits and improvement suggestions directly. These interactions drive us to trial new reagents, re-run wash cycles, and upgrade monitoring tools as soon as real benefit appears in waste minimization or product recovery. Our readiness to adapt comes from understanding the lifecycle of camphanic acid chloride: from the forests producing camphor, through complex synthesis steps, to the handling of every outgoing drum or tank—each node in the chain faces scrutiny and improvement. Traders and outsourcing-based suppliers rarely address these aspects with the same depth because direct process accountability never touches their door.

    Supporting Customer Innovation from Process to Market

    Innovation in fine chemicals and life science manufacturing depends on intermediates that enable new routes, higher yields, or tougher quality control. Our work with (+)-Camphanic acid chloride illustrates how hands-on chemical production links to downstream process gains. For years, R&D teams have relied on our technical staff for advice on protecting group strategies, racemization prevention, and scale-up troubleshooting. Our technical support draws on actual plant production statistics and an archive of case studies reflecting both successes and unexpected snags. This database, shared with permission, aids not only established customers but also new market entrants navigating complex chemical transformations for the first time.

    Time after time, small molecule synthesis projects push process limits—reaction times, solvent compatibilities, color stability, and filtration efficiency. We measure each variable not just for regulatory compliance but for bottom-line reliability: will this lot perform on the kilo scale as it did in the flask? Does storage time affect the reaction profile for a specific peptide? Our warehouse, QA lab, and pilot plant feed these answers into a shared knowledge base that tracks more than numbers—real user experience filters every technical recommendation. This is the heartbeat of a manufacturer’s pride: seeing people solve real problems by integrating our product into their work, then coming back to tell us what took them further and what direction we could grow next.

    Addressing Market Volatility and Global Supply Chains

    Fluctuations in raw material pricing, freight dislocation, and policy updates affect every specialty chemical over time. Our operational roots anchor us through cycles when others scramble to secure short-term alternatives. Sourcing camphor directly, vetting supply chains for transparency, and maintaining stocks built around historical demand all come from manufacturing experience—not from spreadsheets supplied by upstream traders. As global import regulations tighten, our established protocols for customs compliance, product documentation, and safety recordkeeping protect both our production schedules and customer timelines.

    Recent years have underlined the importance of robust local networks paired with global outlook. We maintain relationships with transport partners familiar with the quirks of shipping moisture-sensitive acid chlorides. Our staff trains with emergency response exercises based on actual incidents, not just simulations, so they can handle temperature excursions and leaks if they ever happen in a truck or port warehouse. Track-and-trace, digital labeling, and online documentation portals all facilitate faster communication; these steps come from people who know how frustrating delays and lost batches can be. Customers buying acid chloride from us trust the product to arrive safely and as expected regardless of external market stress—earned through decades of meeting real-world challenges head-on.

    Long-Term Perspective Powers Sustainable Partnerships

    Strategic partnership grows from mutual reliability rather than transactional convenience. As a chemical manufacturer, we see long-term repeat customers as the foundation of sustained growth, not one-time deals. The full process understanding gained by investing in dedicated production equipment, training, and support staff transfers to every ton shipped. This perspective supports honest conversation about future forecasts, cooperative adaptation when new regulatory or formulation challenges arise, and shared investment in next-generation chemical solutions. Purchasing camphanic acid chloride from a plant operator brings with it trusted advice, fast feedback cycles, and opportunities for process integration at the earliest design stages.

    For customers developing new synthetic routes, product launches, or alternative active ingredients, early engagement with the manufacturer creates options that would be invisible on the open market. Our technical and operational leadership team frequently shares pilot data, risk analysis, and alternatives to optimize economics or improve robustness against seasonal swings or policy shifts. The resulting partnerships lead to a stronger ecosystem for all involved—product reliability, shared environmental stewardship, and joint problem solving.

    Moving Forward—Supporting Excellence in Specialty Chemicals

    Every drum of (+)-Camphanic acid chloride that leaves our loading dock reflects collaboration between plant operators, technical teams, quality assurance, and end users. Our commitment stems from the hard-earned lessons of producing, packaging, and shipping a specialty chemical where details matter. Whether as a chiral auxiliary in an advanced pharmaceutical route or as a protecting group in a new industrial process, the work of hands-on manufacturing makes the difference between routine supply and genuine reliability. As both global markets and specialty applications continue to evolve, our experience roots innovation in the realities of everyday production, helping partners—both established and new—build success on a foundation of tangible quality and shared expertise.