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HS Code |
122105 |
| Name | Caffeine |
| Chemical Formula | C8H10N4O2 |
| Molecular Weight | 194.19 g/mol |
| Appearance | white, odorless, crystalline solid |
| Melting Point | 238 °C |
| Solubility In Water | 2.17 g/100 mL at 25 °C |
| Cas Number | 58-08-2 |
| Boiling Point | 178 °C (sublimes) |
| Density | 1.23 g/cm³ |
| Common Sources | coffee, tea, soft drinks, energy drinks, chocolate |
| Iupac Name | 1,3,7-Trimethylpurine-2,6-dione |
| Pka | 14.0 |
| Bioavailability | 99% (oral) |
| Metabolism | liver (cytochrome P450 1A2) |
| Half Life | 3-5 hours (varies by individual) |
As an accredited Caffeine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White, opaque plastic bottle labeled "Caffeine, 100g" with chemical formula, hazard symbols, safety instructions, manufacturer details, and batch number. |
| Shipping | Caffeine is typically shipped as a solid powder or in tablet form, packaged in airtight, moisture-proof containers to prevent degradation. It should be labeled appropriately, indicating it is a chemical substance. Follow local and international regulations. Store and transport in a cool, dry place, away from incompatible substances and direct sunlight. |
| Storage | Caffeine should be stored in a tightly sealed container, protected from light and moisture, at room temperature (15–25°C or 59–77°F). Keep it away from incompatible substances, such as strong oxidizing agents. Store it in a cool, dry, well-ventilated area, clearly labeled, and out of reach of unauthorized personnel to ensure chemical stability and safety. |
Applications of Caffeine in Industrial ManufacturingCaffeine serves as a specialized functional ingredient across multiple regulated industrial sectors, supported by recognized compliance frameworks and stringent quality systems. As a chemical raw material manufacturer with decades of production experience, we supply high-purity caffeine for use in tightly controlled downstream applications that demand precise formulation and industry certification. Below, we detail several major deployment scenarios, highlighting key compliance standards, formulation guidance, process integration points, and representative finished goods. 1. Formulated Energy BeveragesEnergy drink manufacturers require strictly compliant caffeine inputs to deliver products with reliable energizing effect, predictable sensory profile, and fully documented traceability. The ingredient must comply with local and international food safety frameworks, and addition rates must align with jurisdictional limits for total caffeine in beverages. Industrial batch production introduces caffeine during the liquid blending or syrup compounding stage for precise dispersion and homogeneity, supporting downstream bottling, pasteurization, and shelf stability. Finished goods span carbonated energy drinks, still energy beverages, and pre-mixed energy shots, delivered in various packaging formats for global markets. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Pharmaceutical Tablet and Capsule FormulationCaffeine acts as a stimulant active and adjuvant in multiple oral solid dosage forms, supporting alertness and reducing drowsiness. The excipient grade supplied for pharmaceutical use complies with pharmacopeial requirements and GMP manufacturing standards, accompanied by a complete documentation suite and repeatable particle size, impurity, and microbiological control. Manufacturers integrate caffeine during API dry blending or direct compression, with downstream processes ensuring accurate content uniformity, dissolution rate, and stability as validated through in-process and finished product QC. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Functional Confectionery ManufacturingFood-grade caffeine is utilized by manufacturers of functional chewing gum, candies, and lozenges designed to deliver controlled stimulant effect in convenient on-the-go formats. Producers integrate precisely weighed caffeine during the syrup or gum base mixing phase, necessitating rapid, uniform inclusion to prevent hot spots and ensure batch homogeneity. Regulatory limits for the confectionery segment require careful compliance, and process validation uses finished product sampling and HPLC or UPLC for release testing. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Personal Care and Cosmetic PreparationsSpecialty cosmetic manufacturers incorporate caffeine in skin care and scalp preparations for purported stimulating and soothing benefits when delivered through topical application. Entry forms include solutions, dispersions, and micronized powders, often standardized for cosmetic use, with ingredient traceability and absence of residual solvents. Caffeine enters the emulsion or batch concentrate stage and must remain stable under pH and temperature conditions typical for high-throughput filling and storage. Downstream quality control validates both composition and finished product potency, supporting a range of innovative consumer cosmetic formats. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Veterinary Pharmaceuticals and Feed SupplementsVeterinary pharmaceutical manufacturers use pharmaceutical-grade caffeine as a component of respiratory and circulatory stimulants administered to companion animals and livestock under strict veterinary regulations. Additions occur under prescription or controlled feed protocols, requiring reliable documentation of purity and origin. Formulators incorporate caffeine as an active during premix or solution compounding, followed by dispensing into dose-controlled forms. Quality attributes must pass pharmacopoeia and veterinary-specific monographs, and finished goods require precise labelling, stability, and safety assessments to pass regulatory registration. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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Competitive Caffeine prices that fit your budget—flexible terms and customized quotes for every order.
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Our facility has produced caffeine for decades, adapting our processes to the evolving needs of food and pharmaceutical customers. Caffeine’s crisp, bitter taste and stimulating properties make it an essential ingredient across countless energy drinks, soft beverages, and over-the-counter medications. As a chemical manufacturer, we handle raw caffeine synthesis from start to finish, watching closely over every stage, from the crystallization of the ultrapure form to the careful drying and packaging in high-barrier materials. This hands-on manufacturing approach produces caffeine with consistent qualities: bright white, free-flowing crystals, odorless but with unmistakable profile. We believe that direct oversight brings reliable outcomes that customers trust every batch.
Industry users rarely get to see this side of caffeine’s journey. They rely on the familiarity of their finished products, but the foundation traces back through rigorous checks. Caffeine splits into two broad models in the market: anhydrous (water-free) and monohydrate (crystal chemically bound with water). On our line, most output leaves as anhydrous caffeine, prized for its stability, higher purity, and accurate dosing in sensitive applications. Energy drink producers count on it to dissolve quickly and blend evenly. In pharmaceutical settings—tablets, caplets, or pain relief combos—measured anhydrous caffeine combines predictably with other actives. That consistent solubility matters when a production halt over clumping or off-spec potency can cost hours of downtime and lost batches.
Caffeine usually starts from a plant extract or, in our case, from a synthetic process. Decaffeinated coffee production produces much of the world’s supply, but synthetic routes—what we operate—strip away organic impurities that natural extracts introduce. Purer input means fewer headaches down the process, especially for pharmaceutical buyers facing strict regulations.
Our manufacturing runs on validated GMP (Good Manufacturing Practice) lines. Each lot undergoes HPLC (High-Performance Liquid Chromatography) analysis, confirming purity above 99.5%. We reject material showing trace residues, off-colors, or moisture outside tight bounds, because even small deviations risk product recalls in the field. Our QC team, experienced from years on the floor, recognizes base trends in particle size, solubility, and reactivity—factors that influence how caffeine handles under high-speed blending or tabletting. That expertise helps us tweak drying times, adjust grinding settings, and adopt new process controls, keeping downstream partners running smoothly.
People know caffeine for the jolt it brings in a morning cup of coffee, but our customers seek a technical ingredient. Beverage makers use caffeine to enhance flavor, sharpen alertness, and provide “kick.” Pharmaceutical clients prize its synergy in pain relievers, where caffeine speeds absorption and boosts the effect of analgesics. We’ve supported new formula launches, troubleshooting foaming issues when energy syrup mixers struggled to dissolve cheaper grades, and helping accuracy in blister packs where exact weight matters for each tablet.
Caffeine does more than just stimulate—it plays a functional role in food and pharma formulation. Large international drink brands test each batch, demanding a quick-dissolving grade that prevents cloudy bottoms or unappealing sediment. In our plant, we invested in milling technology that generates a specific particle distribution. Too coarse, and the powder settles. Too fine, and static cling gums up mixing equipment. We measure particle size strictly before release, so even industrial blenders working at three shifts can keep up production with fewer stoppages. Pharmaceutical lines require even tighter quality—batch-to-batch consistency in uniformity, verified by our finished product HPLC trace.
Plenty of newcomers have entered the market—guarana extracts, yerba mate, and synthetic analogues. Some offer similar effects in beverages or preworkout powders. What sets caffeine apart comes down to regulatory familiarity, dose control, and safety data. Global health agencies have studied caffeine inside and out, setting clear upper limits and outlining restrictions. That gives beverage companies and pharmaceutical houses a solid foundation: formulas built with standardized, anhydrous caffeine face less regulatory friction and fewer surprises in labeling or toxicology review. The safety profile of caffeine stands unlike newer, untested extracts facing changing guidance around allergens, contaminants, or unknown metabolites.
As a manufacturer, we’ve fielded requests to swap caffeine for novel extracts. Our team runs side-by-side trials, tracking dissolution, color, and activity. Despite the hype, guarana brings inconsistent potency—we see variability between crops, seasonal changes, and persistent sap-like aromas. Synthetic analogues drift farther, sometimes triggering regulatory pushback or unexpected side effects in early testing. Caffeine, by contrast, offers purchasers the comfort of traceability. Each drum issued from our plant carries batch records, HPLC certification, and full documentation for audits. Whether used in branded drinks or national OTC pain relievers, partners rely on stable compositions season after season.
We supply caffeine as a crystalline, colorless powder. Most lots read above 99.5% on HPLC purity—a practical cutpoint for both beverage blending and pharmaceutical classes. Moisture readings stay under 0.5%, since water promotes caking and degrades active content during storage. Packaging matters, especially for high-humidity regions; we use sealed, food-grade liners around fiber drums to prevent uptake and contamination during transit or warehousing.
Our shipping team knows what happens to poorly packed caffeine. Open bins attract odor or moisture, moodling product performance. We advise customers new to the material—never store open drums near chemicals or on low warehouse pallets. Simple steps keep solubility and flow properties in peak form, translating to fewer rejected units in manufacturing. For very fine granulation needs, we use custom air-milling setups, getting particle sizes tailored for rapid wetting in beverage pre-mixes. A pharmaceutical buyer may request micron-size crystals; our millers adjust screens and vacuum feeders so each delivery meets that demand, with particle counts confirmed pre-shipment.
The market sees shifts in demand. Regulatory authorities in some regions review ingredient sourcing and labeling closely, especially for products targeting children or the supplement trade. Our plant runs regular cross-checks on raw material sources—verifying no undeclared plant alkaloids slip into synthetic caffeine runs. We’ve heard from partners about batch recalls elsewhere triggered by cross-contamination. Our method—isolated process lines, frequent swab tests, and third-party audits—delivers assurance that no unexpected substances ride along with our finished powder.
Dosing remains another challenge downstream. Too much caffeine in the blend, and labeled foods or beverages run afoul of regional limits. Too little, and users complain of weak effects. For several customers, especially co-packers juggling multiple products, we’ve supported dosing verification by sharing detailed purity data. Providing this information enables accurate, repeatable mixing recipes. Sometimes, new startups approach us after inconsistent results using resold or unknown caffeine. Visibility into actual purity, particle profile, and drying time helps them reboot production lines for more stable yields.
Caffeine’s stability forms the backbone of our product strategy. Heat, light, and humidity shake the quality of natural extracts but rarely trouble our synthetic caffeine, packaged and shipped under rigorous controls. Even so, no product lasts forever. We help partners manage stock rotation and optimal dosing, consulting on packaging solutions that delay degradation and maintain potency even in tough climates. Small details—like lining choice for 25kg drums—hold up under cross-country shipping. We recommend working with manufacturing partners who share this attention to post-delivery product care.
Direct manufacturing offers clear advantages over buying caffeine from resellers or brokers. Our technical teams field real-world questions—how to resolve caking in large silos, the best particle size for instant beverage mixes, or how to validate caffeine content in regulatory filings. This feedback shapes process improvements: slower crystal drying cycles, new filtration to capture fines, or custom blending for hard-to-dissolve mixes. Our plant’s documentation gives partners peace of mind at each handoff, streamlining compliance checks and speeding up new product launches.
Manufacturing on-site provides access to technical support and adaptation. Some clients require smaller lots, rapidly delivered with tight specification adherence for sensitive R&D runs. Others scale up, needing thousand-kilo deliveries every week. Our scheduling team balances these requirements, tracking lot genealogy, and anticipating periodic process adjustments. Rather than relying on word-of-mouth quality or generic samples from untraceable sources, our model supports audits, visitor tours, and direct communication on technical concerns. Most partners keep coming back for this transparency and readiness to tackle manufacturing snags head-on.
Real-world challenges frequently arise with caffeine. Bulk delivery in humid climates, storage next to odor-producing products, and inadvertent blending errors cause trouble for the unwary. From years handling caffeine in industrial quantities, we’ve built a set of workable solves. For instance, we run loading lines in a low-humidity cleanroom area, extending product shelf life by keeping moisture out at the bottleneck. Our packaging employs triple-layer lining, giving extra insurance for ocean or long-haul truck shipments.
In manufacturing environments, static control matters. Small changes in the grind can create flow problems, stalling high-speed lines. We work closely with maintenance leads, monitoring feedback on feed rates and downtime. Quick response—sometimes sending a fresh lot on the next truck—keeps production on track, minimizing loss. Knowing that each shipment traces back directly to our quality team gives clients the confidence to fix problems quickly.
Accuracy in specification reporting is critical. Some customers have described issues when purchasing caffeine labeled at “pharmaceutical grade” but traced to repackaged feed or food supply material. In these cases, certificates seldom match the traceability or test history our facility provides. Years of audit experience have shaped our release criteria: every drum ships with COA and complete documentation, and our logs stretch back for multiple years of lot history—details that matter for regulated customers or brand-sensitive partners facing random inspections or product challenges.
Trends come and go in food and beverage innovation, but caffeine’s security as an approved, well-studied, and reliable stimulant remains. Companies worldwide rely on a deep regulatory acceptance and thorough substance characterization, giving them surety in both development and mass production. The synthetic, manufacturer-direct approach adds another level of control, reducing risks tied to otherwise variable botanicals or unpredictable third-party sources. From the standpoint of quality, consistency, and data support, few ingredients match caffeine’s standing.
Our technical, operations, and support staff stay available for customer questions and ongoing technical improvement. Whether optimizing an energy drink run, troubleshooting a new tabletting process, or working through changing regulatory needs in a new market, years of hands-on production feed the insight and problem-solving needed across applications. We treat caffeine not as a commodity but as a precision ingredient—anchored in scientific test data, client feedback, and continuous investment in process stability.
Sweeping consumer expectations about transparency and traceability raise the bar for every ingredient supplier. Our caffeine products reflect that shift. From on-site validation labs to robust tracking of every raw input, we respond with openness and validated scientific practices. While other ingredients encounter controversy or shifting legal ground, caffeine’s compliance profile and test history stand strong, winning trust from major brands and small beverage innovators alike.
As we look to future growth areas—lower-dose formulations for children’s products, clean-label opportunities in natural energy sets, or smart packaging to preserve freshness—the core foundation of manufacturer control lets us adapt quickly. Customers bring fresh technical puzzles; our staff draws on years of hands-on know-how to resolve them without sacrificing throughput or shipment timelines. From regulatory submissions to day-to-day supplier support, direct experience in caffeine manufacturing gives our confidence that the material not only meets, but anticipates industry need.
Caffeine’s status as a vital stimulant ingredient results from years of trust—built batch by batch, truckload by truckload, and product launch by product launch. As a long-term manufacturer, we believe our commitment to quality, technical expertise, and transparent communication continues that legacy in every shipment that leaves our plant.